Gene Symbol | TAF15 |
Entrez Gene ID | 8148 |
Full Name | TATA-box binding protein associated factor 15 |
Synonyms | Npl3,RBP56,TAF2N,TAFII68 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]. |
Disorder MIM: | |
Disorder Html: | Chondrosarcoma, extraskeletal myxoid, 612237 (1) |