AAAS cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AAAS
Entrez Gene ID	8086
Full Name	aladin WD repeat nucleoporin
Synonyms	AAA,AAASb,ADRACALA,ADRACALIN,ALADIN,GL003
General protein information	Preferred Names aladin WD repeat nucleoporin Names aladin Allgrove, triple-A achalasia, adrenocortical insufficiency, alacrimia
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.13
Summary	The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
Disorder MIM:	605378
Disorder Html:	Achalasia-addisonianism-alacrimia syndrome, 231550 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001173466.1	NP_001166937.1	aladin isoform 2
XM_011538780.2	XP_011537082.1	aladin isoform X2
NM_015665.6	NP_056480.1	aladin isoform 1
XM_011538778.1	XP_011537080.1	aladin isoform X1
NM_001173466.2	NP_001166937.1	aladin isoform 2
XM_011538780.1	XP_011537082.1	aladin isoform X2
NM_015665.5	NP_056480.1	aladin isoform 1
XM_011538778.2	XP_011537080.1	aladin isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	AAAS	NP_056480.1
Bos taurus (cattle)	AAAS	NP_001068737.1
Mus musculus (house mouse)	Aaas	NP_700465.2
Rattus norvegicus (Norway rat)	Aaas	NP_001100265.1
Danio rerio (zebrafish)	aaas	NP_998390.1
Oryza sativa (rice)	Os11g0132700	NP_001065665.1
Xenopus tropicalis (tropical clawed frog)	aaas	XP_002936677.1
Canis lupus familiaris (dog)	AAAS	XP_849797.3
Drosophila melanogaster (fruit fly)	CG16892	NP_572557.1
Pan troglodytes (chimpanzee)	AAAS	NP_001233360.1
Gallus gallus (chicken)	AAAS	XP_003643473.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010685	XP_311401.4
Arabidopsis thaliana (thale cress)	AT3G56900	NP_191249.2

Gene Ontology
Bibliography

Related articles in PubMed

Clinical and genetic characterisation of a series of patients with triple A syndrome.
Kurnaz E, Duminuco P, Aycan Z, Sava?-Erdeve ?, Murato?lu ?ahin N, Keskin M, Bayramo?lu E, Bonomi M, ?etinkaya S
European journal of pediatrics(2017 Dec)

Triple-A syndrome: a wide spectrum of adrenal dysfunction.
Roucher-Boulez F, Brac de la Perri?re A, Jacquez A, Chau D, Guignat L, Vial C, Morel Y, Nicolino M, Raverot G, Pugeat M
European journal of endocrinology(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that a single splicing mutation affects the AAAS transcripts and consequently the ALADIN protein structure and function.
Title: Splicing Defects in the AAAS Gene Leading to both Exon Skipping and Partial Intron Retention in a Tunisian Patient with Allgrove Syndrome.

Triple A syndrome with a novel indel mutation in the AAAS gene and delayed puberty.
Title: Triple A syndrome with a novel indel mutation in the AAAS gene and delayed puberty.

down-regulating ALADIN results in decreased oxidative stress response leading to alteration in steroidogenesis, highlighting our knock-down cell model as an important in-vitro tool for studying the adrenal phenotype in triple A syndrome
Title: Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis.

Data suggest ALADIN is involved in resistance to oxidative stress in adrenocortical cells/neurons; ALADIN knockdown down-regulates StAR (steroidogenic acute regulatory protein) and P45011beta (cytochrome P450 family 11 subfamily B polypeptide 1).
Title: Deficiency of ALADIN impairs redox homeostasis in human adrenal cells and inhibits steroidogenesis.

The compromising c.43C>A mutation is predicted to cause a p.Gln15Lys amino acid substitution in the ALADIN protein.
Title: The genetic basis of triple A (Allgrove) syndrome in a Greek family.

The following AAAS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AAAS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18022	NM_015665.6 Latest version!	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu16901	NM_001173466.2 Latest version!	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OHu61625	XM_011538778.2 Latest version!	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu61627	XM_011538780.2 Latest version!	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu16901	NM_001173466.1	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OHu61627	XM_011538780.1	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu18022	NM_015665.5	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu61625	XM_011538778.1	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AAAS ( NM_015665.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_056480.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18022
Clone ID Related Accession (Same CDS sequence)	NM_015665.6 , NM_015665.5
Accession Version	NM_015665.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	aladin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC393722.1 and AJ289857.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_015665.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.363110.1, SRR3476690.787273.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000209873.9/ ENSP00000209873.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GTGGCATTAT CCAGGGGGAG CCAGGAGCCC AGCCCCAGCT CATCACTTTC 
CATCCTTCCT TCAACAAAGG GGCCCTGCTC AGTGTGGGCT GGTCCACAGG CCGAATTGCC 
CACATCCCGC TGTACTTTGT CAATGCCCAG TTTCCACGTT TTAGCCCAGT GCTTGGGCGG 
GCCCAGGAAC CCCCTGCTGG GGGTGGAGGC TCTATTCATG ACCTGCCCCT CTTTACTGAG 
ACATCCCCAA CCTCTGCCCC TTGGGACCCT CTCCCAGGGC CACCACCTGT TCTGCCCCAC 
TCCCCACATT CCCACCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056480.1
CDS	146..1786
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNASSTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	NM_015665.6
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015665.6

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GTGGCATTAT CCAGGGGGAG CCAGGAGCCC AGCCCCAGCT CATCACTTTC 
CATCCTTCCT TCAACAAAGG GGCCCTGCTC AGTGTGGGCT GGTCCACAGG CCGAATTGCC 
CACATCCCGC TGTACTTTGT CAATGCCCAG TTTCCACGTT TTAGCCCAGT GCTTGGGCGG 
GCCCAGGAAC CCCCTGCTGG GGGTGGAGGC TCTATTCATG ACCTGCCCCT CTTTACTGAG 
ACATCCCCAA CCTCTGCCCC TTGGGACCCT CTCCCAGGGC CACCACCTGT TCTGCCCCAC 
TCCCCACATT CCCACCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( NM_001173466.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166937.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16901
Clone ID Related Accession (Same CDS sequence)	NM_001173466.1 , NM_001173466.2
Accession Version	NM_001173466.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Homo sapiens(human)
Product	aladin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC393722.1, AY237818.1, AJ289857.1 and BC000659.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY237818.1, AK293342.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGTGGCATTA TCCAGGGGGA GCCAGGAGCC 
CAGCCCCAGC TCATCACTTT CCATCCTTCC TTCAACAAAG GGGCCCTGCT CAGTGTGGGC 
TGGTCCACAG GCCGAATTGC CCACATCCCG CTGTACTTTG TCAATGCCCA GTTTCCACGT 
TTTAGCCCAG TGCTTGGGCG GGCCCAGGAA CCCCCTGCTG GGGGTGGAGG CTCTATTCAT 
GACCTGCCCC TCTTTACTGA GACATCCCCA ACCTCTGCCC CTTGGGACCC TCTCCCAGGG 
CCACCACCTG TTCTGCCCCA CTCCCCACAT TCCCACCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166937.1
CDS	164..1705
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNCTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	NM_001173466.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173466.1

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGTGGCATTA TCCAGGGGGA GCCAGGAGCC 
CAGCCCCAGC TCATCACTTT CCATCCTTCC TTCAACAAAG GGGCCCTGCT CAGTGTGGGC 
TGGTCCACAG GCCGAATTGC CCACATCCCG CTGTACTTTG TCAATGCCCA GTTTCCACGT 
TTTAGCCCAG TGCTTGGGCG GGCCCAGGAA CCCCCTGCTG GGGGTGGAGG CTCTATTCAT 
GACCTGCCCC TCTTTACTGA GACATCCCCA ACCTCTGCCC CTTGGGACCC TCTCCCAGGG 
CCACCACCTG TTCTGCCCCA CTCCCCACAT TCCCACCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( NM_001173466.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166937.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16901
Clone ID Related Accession (Same CDS sequence)	NM_001173466.1 , NM_001173466.2
Accession Version	NM_001173466.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	aladin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC393722.1, AY237818.1, AJ289857.1 and BC000659.2. On Jun 1, 2019 this sequence version replaced NM_001173466.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.506081.1, AY237818.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGTGGCATTA TCCAGGGGGA GCCAGGAGCC 
CAGCCCCAGC TCATCACTTT CCATCCTTCC TTCAACAAAG GGGCCCTGCT CAGTGTGGGC 
TGGTCCACAG GCCGAATTGC CCACATCCCG CTGTACTTTG TCAATGCCCA GTTTCCACGT 
TTTAGCCCAG TGCTTGGGCG GGCCCAGGAA CCCCCTGCTG GGGGTGGAGG CTCTATTCAT 
GACCTGCCCC TCTTTACTGA GACATCCCCA ACCTCTGCCC CTTGGGACCC TCTCCCAGGG 
CCACCACCTG TTCTGCCCCA CTCCCCACAT TCCCACCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166937.1
CDS	146..1687
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNCTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	NM_001173466.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173466.2

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGTGGCATTA TCCAGGGGGA GCCAGGAGCC 
CAGCCCCAGC TCATCACTTT CCATCCTTCC TTCAACAAAG GGGCCCTGCT CAGTGTGGGC 
TGGTCCACAG GCCGAATTGC CCACATCCCG CTGTACTTTG TCAATGCCCA GTTTCCACGT 
TTTAGCCCAG TGCTTGGGCG GGCCCAGGAA CCCCCTGCTG GGGGTGGAGG CTCTATTCAT 
GACCTGCCCC TCTTTACTGA GACATCCCCA ACCTCTGCCC CTTGGGACCC TCTCCCAGGG 
CCACCACCTG TTCTGCCCCA CTCCCCACAT TCCCACCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( NM_015665.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056480.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.

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CloneID	OHu18022
Clone ID Related Accession (Same CDS sequence)	NM_015665.6 , NM_015665.5
Accession Version	NM_015665.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	aladin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC393722.1, AJ289857.1 and BC000659.2. This sequence is a reference standard in the RefSeqGene project. On Apr 2, 2008 this sequence version replaced NM_015665.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.104593.1, SRR1163658.564357.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GTGGCATTAT CCAGGGGGAG CCAGGAGCCC AGCCCCAGCT CATCACTTTC 
CATCCTTCCT TCAACAAAGG GGCCCTGCTC AGTGTGGGCT GGTCCACAGG CCGAATTGCC 
CACATCCCGC TGTACTTTGT CAATGCCCAG TTTCCACGTT TTAGCCCAGT GCTTGGGCGG 
GCCCAGGAAC CCCCTGCTGG GGGTGGAGGC TCTATTCATG ACCTGCCCCT CTTTACTGAG 
ACATCCCCAA CCTCTGCCCC TTGGGACCCT CTCCCAGGGC CACCACCTGT TCTGCCCCAC 
TCCCCACATT CCCACCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056480.1
CDS	164..1804
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNASSTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	NM_015665.5
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015665.5

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GTGGCATTAT CCAGGGGGAG CCAGGAGCCC AGCCCCAGCT CATCACTTTC 
CATCCTTCCT TCAACAAAGG GGCCCTGCTC AGTGTGGGCT GGTCCACAGG CCGAATTGCC 
CACATCCCGC TGTACTTTGT CAATGCCCAG TTTCCACGTT TTAGCCCAGT GCTTGGGCGG 
GCCCAGGAAC CCCCTGCTGG GGGTGGAGGC TCTATTCATG ACCTGCCCCT CTTTACTGAG 
ACATCCCCAA CCTCTGCCCC TTGGGACCCT CTCCCAGGGC CACCACCTGT TCTGCCCCAC 
TCCCCACATT CCCACCTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( XM_011538778.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537080.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.

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CloneID	OHu61625
Clone ID Related Accession (Same CDS sequence)	XM_011538778.1 , XM_011538778.2
Accession Version	XM_011538778.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	aladin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GCTCCCTTCT TGCCTCCGGT TGCCTGCTCA CCTTTTCTTC TAGTGGCATT 
ATCCAGGGGG AGCCAGGAGC CCAGCCCCAG CTCATCACTT TCCATCCTTC CTTCAACAAA 
GGGGCCCTGC TCAGTGTGGG CTGGTCCACA GGCCGAATTG CCCACATCCC GCTGTACTTT 
GTCAATGCCC AGTTTCCACG TTTTAGCCCA GTGCTTGGGC GGGCCCAGGA ACCCCCTGCT 
GGGGGTGGAG GCTCTATTCA TGACCTGCCC CTCTTTACTG AGACATCCCC AACCTCTGCC 
CCTTGGGACC CTCTCCCAGG GCCACCACCT GTTCTGCCCC ACTCCCCACA TTCCCACCTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537080.1
CDS	96..1778
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNASSTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCSLLASGCLLTFSSSGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	XM_011538778.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538778.1

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GCTCCCTTCT TGCCTCCGGT TGCCTGCTCA CCTTTTCTTC TAGTGGCATT 
ATCCAGGGGG AGCCAGGAGC CCAGCCCCAG CTCATCACTT TCCATCCTTC CTTCAACAAA 
GGGGCCCTGC TCAGTGTGGG CTGGTCCACA GGCCGAATTG CCCACATCCC GCTGTACTTT 
GTCAATGCCC AGTTTCCACG TTTTAGCCCA GTGCTTGGGC GGGCCCAGGA ACCCCCTGCT 
GGGGGTGGAG GCTCTATTCA TGACCTGCCC CTCTTTACTG AGACATCCCC AACCTCTGCC 
CCTTGGGACC CTCTCCCAGG GCCACCACCT GTTCTGCCCC ACTCCCCACA TTCCCACCTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( XM_011538778.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537080.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61625
Clone ID Related Accession (Same CDS sequence)	XM_011538778.1 , XM_011538778.2
Accession Version	XM_011538778.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	aladin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011538778.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GCTCCCTTCT TGCCTCCGGT TGCCTGCTCA CCTTTTCTTC TAGTGGCATT 
ATCCAGGGGG AGCCAGGAGC CCAGCCCCAG CTCATCACTT TCCATCCTTC CTTCAACAAA 
GGGGCCCTGC TCAGTGTGGG CTGGTCCACA GGCCGAATTG CCCACATCCC GCTGTACTTT 
GTCAATGCCC AGTTTCCACG TTTTAGCCCA GTGCTTGGGC GGGCCCAGGA ACCCCCTGCT 
GGGGGTGGAG GCTCTATTCA TGACCTGCCC CTCTTTACTG AGACATCCCC AACCTCTGCC 
CCTTGGGACC CTCTCCCAGG GCCACCACCT GTTCTGCCCC ACTCCCCACA TTCCCACCTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537080.1
CDS	121..1803
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNASSTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCSLLASGCLLTFSSSGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	XM_011538778.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538778.2

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGGTCC AGCTGCTGCT TGCGTGTCTT TGCATGGCAC 
CCCCACACCA ACAAGTTTGC AGTGGCCCTG CTAGATGACT CAGTCCGTGT GTATAATGCC 
AGCAGCACCA TAGTCCCCTC CCTGAAGCAC CGGCTGCAGC GAAATGTGGC GTCTCTGGCC 
TGGAAGCCCC TTAGTGCCTC TGTCTTGGCT GTGGCCTGCC AGAGCTGCAT TCTTATCTGG 
ACCCTGGACC CTACCTCCTT GTCTACCCGA CCCTCTTCTG GCTGTGCCCA AGTGCTGTCT 
CACCCTGGGC ATACACCTGT TACCAGCTTG GCCTGGGCCC CCAGTGGGGG GCGGCTGCTC 
TCAGCTTCAC CCGTGGATGC TGCTATCCGG GTATGGGATG TCTCAACAGA GACCTGTGTC 
CCCCTTCCCT GGTTCCGAGG AGGTGGGGTG ACCAACCTGC TCTGGTCCCC AGACGGCAGC 
AAAATCCTGG CTACCACTCC TTCAGCTGTC TTTCGAGTCT GGGAGGCCCA GATGTGGACT 
TGTGAGAGGT GGCCTACTCT ATCAGGGCGC TGTCAGACTG GCTGCTGGAG CCCAGATGGC 
AGCCGACTGC TGTTCACTGT ATTGGGAGAG CCACTGATTT ACTCCCTGTC TTTTCCAGAA 
CGTTGTGGTG AGGGAAAGGG GTGCGTTGGA GGTGCAAAGT CAGCAACGAT TGTGGCAGAT 
CTGTCTGAGA CAACAATACA GACACCAGAT GGTGAGGAGA GGCTTGGGGG AGAGGCTCAC 
TCCATGGTCT GGGACCCCAG TGGGGAACGT CTGGCTGTGC TTATGAAAGG AAAGCCAAGG 
GTACAGGATG GTAAACCAGT CATCCTCCTT TTTCGCACTC GAAACAGCCC TGTGTTTGAG 
CTCCTTCCCT GCTCCCTTCT TGCCTCCGGT TGCCTGCTCA CCTTTTCTTC TAGTGGCATT 
ATCCAGGGGG AGCCAGGAGC CCAGCCCCAG CTCATCACTT TCCATCCTTC CTTCAACAAA 
GGGGCCCTGC TCAGTGTGGG CTGGTCCACA GGCCGAATTG CCCACATCCC GCTGTACTTT 
GTCAATGCCC AGTTTCCACG TTTTAGCCCA GTGCTTGGGC GGGCCCAGGA ACCCCCTGCT 
GGGGGTGGAG GCTCTATTCA TGACCTGCCC CTCTTTACTG AGACATCCCC AACCTCTGCC 
CCTTGGGACC CTCTCCCAGG GCCACCACCT GTTCTGCCCC ACTCCCCACA TTCCCACCTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( XM_011538780.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537082.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.

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CloneID	OHu61627
Clone ID Related Accession (Same CDS sequence)	XM_011538780.2 , XM_011538780.1
Accession Version	XM_011538780.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	aladin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011538780.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGCTCCCTTC TTGCCTCCGG TTGCCTGCTC 
ACCTTTTCTT CTAGTGGCAT TATCCAGGGG GAGCCAGGAG CCCAGCCCCA GCTCATCACT 
TTCCATCCTT CCTTCAACAA AGGGGCCCTG CTCAGTGTGG GCTGGTCCAC AGGCCGAATT 
GCCCACATCC CGCTGTACTT TGTCAATGCC CAGTTTCCAC GTTTTAGCCC AGTGCTTGGG 
CGGGCCCAGG AACCCCCTGC TGGGGGTGGA GGCTCTATTC ATGACCTGCC CCTCTTTACT 
GAGACATCCC CAACCTCTGC CCCTTGGGAC CCTCTCCCAG GGCCACCACC TGTTCTGCCC 
CACTCCCCAC ATTCCCACCT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537082.1
CDS	121..1704
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNCTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCSLLASGCLLTFSSSGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	XM_011538780.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538780.2

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGCTCCCTTC TTGCCTCCGG TTGCCTGCTC 
ACCTTTTCTT CTAGTGGCAT TATCCAGGGG GAGCCAGGAG CCCAGCCCCA GCTCATCACT 
TTCCATCCTT CCTTCAACAA AGGGGCCCTG CTCAGTGTGG GCTGGTCCAC AGGCCGAATT 
GCCCACATCC CGCTGTACTT TGTCAATGCC CAGTTTCCAC GTTTTAGCCC AGTGCTTGGG 
CGGGCCCAGG AACCCCCTGC TGGGGGTGGA GGCTCTATTC ATGACCTGCC CCTCTTTACT 
GAGACATCCC CAACCTCTGC CCCTTGGGAC CCTCTCCCAG GGCCACCACC TGTTCTGCCC 
CACTCCCCAC ATTCCCACCT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AAAS ( XM_011538780.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011537082.1 Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61627
Clone ID Related Accession (Same CDS sequence)	XM_011538780.2 , XM_011538780.1
Accession Version	XM_011538780.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	aladin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGCTCCCTTC TTGCCTCCGG TTGCCTGCTC 
ACCTTTTCTT CTAGTGGCAT TATCCAGGGG GAGCCAGGAG CCCAGCCCCA GCTCATCACT 
TTCCATCCTT CCTTCAACAA AGGGGCCCTG CTCAGTGTGG GCTGGTCCAC AGGCCGAATT 
GCCCACATCC CGCTGTACTT TGTCAATGCC CAGTTTCCAC GTTTTAGCCC AGTGCTTGGG 
CGGGCCCAGG AACCCCCTGC TGGGGGTGGA GGCTCTATTC ATGACCTGCC CCTCTTTACT 
GAGACATCCC CAACCTCTGC CCCTTGGGAC CCTCTCCCAG GGCCACCACC TGTTCTGCCC 
CACTCCCCAC ATTCCCACCT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011537082.1
CDS	96..1679
Translation	MCSLGLFPPPPPRGQVTLYEHNNELVTGSSYESPPPDFRGQWINLPVLQLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASGWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNCTIVPSLKHRLQRNVASLAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAIRVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKILATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPDGSRLLFTVLGEPLIYSLSFPERCGEGKGCVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGKPRVQDGKPVILLFRTRNSPVFELLPCSLLASGCLLTFSSSGIIQGEPGAQPQLITFHPSFNKGALLSVGWSTGRIAHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHSPHSHL

Target ORF information:

RefSeq Version	XM_011538780.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aladin WD repeat nucleoporin (AAAS), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538780.1

ORF Insert Sequence:

ATGTGCTCTC TGGGGTTGTT CCCTCCTCCA CCGCCTCGGG GTCAAGTCAC CCTATATGAG 
CACAATAACG AGCTGGTGAC GGGCAGTAGC TATGAGAGCC CGCCCCCCGA CTTCCGGGGC 
CAGTGGATCA ATCTTCCTGT CCTACAACTG ACAAAGGATC CCCTAAAGAC CCCTGGAAGG 
CTGGACCATG GCACAAGAAC TGCCTTCATC CATCACCGGG AGCAAGTGTG GAAGAGATGC 
ATCAACATTT GGCGTGATGT GGGCCTTTTT GGGGTGCTAA ATGAAATTGC AAACTCAGAA 
GAAGAGGTGT TTGAGTGGGT GAAGACGGCA TCCGGCTGGG CCCTGGCACT CTGTCGATGG 
GCCTCTTCCC TCCATGGGTC CCTGTTCCCC CATCTGTCTC TCAGGAGCGA AGATCTGATC 
GCTGAATTTG CCCAAGTCAC AAATTGCACC ATAGTCCCCT CCCTGAAGCA CCGGCTGCAG 
CGAAATGTGG CGTCTCTGGC CTGGAAGCCC CTTAGTGCCT CTGTCTTGGC TGTGGCCTGC 
CAGAGCTGCA TTCTTATCTG GACCCTGGAC CCTACCTCCT TGTCTACCCG ACCCTCTTCT 
GGCTGTGCCC AAGTGCTGTC TCACCCTGGG CATACACCTG TTACCAGCTT GGCCTGGGCC 
CCCAGTGGGG GGCGGCTGCT CTCAGCTTCA CCCGTGGATG CTGCTATCCG GGTATGGGAT 
GTCTCAACAG AGACCTGTGT CCCCCTTCCC TGGTTCCGAG GAGGTGGGGT GACCAACCTG 
CTCTGGTCCC CAGACGGCAG CAAAATCCTG GCTACCACTC CTTCAGCTGT CTTTCGAGTC 
TGGGAGGCCC AGATGTGGAC TTGTGAGAGG TGGCCTACTC TATCAGGGCG CTGTCAGACT 
GGCTGCTGGA GCCCAGATGG CAGCCGACTG CTGTTCACTG TATTGGGAGA GCCACTGATT 
TACTCCCTGT CTTTTCCAGA ACGTTGTGGT GAGGGAAAGG GGTGCGTTGG AGGTGCAAAG 
TCAGCAACGA TTGTGGCAGA TCTGTCTGAG ACAACAATAC AGACACCAGA TGGTGAGGAG 
AGGCTTGGGG GAGAGGCTCA CTCCATGGTC TGGGACCCCA GTGGGGAACG TCTGGCTGTG 
CTTATGAAAG GAAAGCCAAG GGTACAGGAT GGTAAACCAG TCATCCTCCT TTTTCGCACT 
CGAAACAGCC CTGTGTTTGA GCTCCTTCCC TGCTCCCTTC TTGCCTCCGG TTGCCTGCTC 
ACCTTTTCTT CTAGTGGCAT TATCCAGGGG GAGCCAGGAG CCCAGCCCCA GCTCATCACT 
TTCCATCCTT CCTTCAACAA AGGGGCCCTG CTCAGTGTGG GCTGGTCCAC AGGCCGAATT 
GCCCACATCC CGCTGTACTT TGTCAATGCC CAGTTTCCAC GTTTTAGCCC AGTGCTTGGG 
CGGGCCCAGG AACCCCCTGC TGGGGGTGGA GGCTCTATTC ATGACCTGCC CCTCTTTACT 
GAGACATCCC CAACCTCTGC CCCTTGGGAC CCTCTCCCAG GGCCACCACC TGTTCTGCCC 
CACTCCCCAC ATTCCCACCT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical and genetic characterisation of a series of patients with triple A syndrome.
European journal of pediatrics(2017 Dec)
Kurnaz E,Duminuco P,Aycan Z,Sava?-Erdeve ?,Murato?lu ?ahin N,Keskin M,Bayramo?lu E,Bonomi M,?etinkaya S

Triple-A syndrome: a wide spectrum of adrenal dysfunction.
European journal of endocrinology(2017 Dec)
Roucher-Boulez F,Brac de la Perri?re A,Jacquez A,Chau D,Guignat L,Vial C,Morel Y,Nicolino M,Raverot G,Pugeat M

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AAAS cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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