EEPD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EEPD1
Entrez Gene ID	80820
Full Name	endonuclease/exonuclease/phosphatase family domain containing 1
Synonyms	HSPC107
General protein information	Preferred Names endonuclease/exonuclease/phosphatase family domain containing 1 Names endonuclease/exonuclease/phosphatase family domain-containing protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p14.2
Disorder MIM:	617192

mRNA and Protein(s)

mRNA	Protein	Name
XM_017012657.1	XP_016868146.1	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X1
XM_017012658.1	XP_016868147.1	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X2
NM_030636.2	NP_085139.2	endonuclease/exonuclease/phosphatase family domain-containing protein 1
NM_030636.3	NP_085139.2	endonuclease/exonuclease/phosphatase family domain-containing protein 1
XM_017012657.2	XP_016868146.1	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X1
XM_017012658.2	XP_016868147.1	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X2

Pathways from BioSystems

Homologies

	EEPD1	XP_001103689.1
Homo sapiens (human)	EEPD1	NP_085139.2
Mus musculus (house mouse)	Eepd1	NP_080465.3
Pan troglodytes (chimpanzee)	EEPD1	XP_001169567.2
Canis lupus familiaris (dog)	EEPD1	XP_865627.3
Rattus norvegicus (Norway rat)	Eepd1	NP_001014110.1
Bos taurus (cattle)	EEPD1	NP_001029581.1
Gallus gallus (chicken)	EEPD1	XP_418838.2
Danio rerio (zebrafish)	eepd1	NP_991322.1
Xenopus tropicalis (tropical clawed frog)	LOC100127792	NP_001106580.1

Gene Ontology
Bibliography

Related articles in PubMed

The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
Hromas R, Kim HS, Sidhu G, Williamson E, Jaiswal A, Totterdale TA, Nole J, Lee SH, Nickoloff JA, Kong KY
Breast cancer research : BCR19(1)122(2017 Nov)

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.
Nelson JK, Koenis DS, Scheij S, Cook EC, Moeton M, Santos A, Lobaccaro JA, Baron S, Zelcer N
Arteriosclerosis, thrombosis, and vascular biology37(3)423-432(2017 Mar)

Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA
The Journal of biological chemistry292(7)2795-2804(2017 02)

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA
PLoS genetics11(12)e1005675(2015 Dec)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EEPD1 is a novel LXR-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1.
Title: EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.

EEPD1 performs a gatekeeper function for replication fork repair by mediating the fork cleavage that permits initiation of HR-mediated repair and restart of stressed forks
Title: Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.

These data demonstrate that genome stability during replication stress is maintained by EEPD1, which initiates HR and inhibits cNHEJ and MMEJ.
Title: EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following EEPD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EEPD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04472	NM_030636.3 Latest version!	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu97524	XM_017012657.2 Latest version!	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu97525	XM_017012658.2 Latest version!	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu04472	NM_030636.2	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu97524	XM_017012657.1	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu97525	XM_017012658.1	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EEPD1 ( NM_030636.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_085139.2 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.

Price & Availability↑

CloneID	OHu04472
Clone ID Related Accession (Same CDS sequence)	NM_030636.2 , NM_030636.3
Accession Version	NM_030636.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN998549.1, AK027386.1 and AC007327.1. On or before Sep 25, 2007 this sequence version replaced XM_001132789.1, XM_001129581.1, NM_030636.1. ##Evidence-Data-START## Transcript exon combination :: AK027386.1, AB051493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG TTCTGCACGG AGCTAAACCA GCCGACCCTG 
CCCAACATCC GCAAGTGGAA GGGGCCCCGG GGATGCTGGA AGGCTGTTGT TGCTGAGAAG 
CCCTCGAGTC AGCTCCAGAA GGGAGCTGGG TATGCAGGAT TCCTATGGGA CGCGGCTGCC 
GGCATGGAGC TGAGAGACGC GGGTTCACAG GAGAGCTCGC CAAGCAACGG GCACGGGAAG 
CTGGCGGGCC CCAGCCCATA CCTCGGGAGG TTCAAGGTGG GAAGTCACGA CCTGACCCTT 
GTTAACCTTC ACCTGGCAGC CCTGACCCTC CTGGGGAGCG AGAATCCCAG CAAGAATCAC 
AGTGATGGCC ACCGGTTGGC GAGCTTTGCA CAGACCCTAC AGGAAACCCT GAAAGGAGAA 
AAGGATGTCA TTATCTTAGG GGATTTTGGC CAAGGGCCAG ACAGCAATGA CTATGATATC 
CTGAGGAAAG AAAAGTTCCA CCACCTGATC CCCGCGCACA CCTTCACCAA CATCAGCACC 
AAGAACCCTC AAGGCTCGAA GTCTCTGGAC AACATCTGGA TCAGTAAAAG CTTAAAGAAG 
GTTTTCACAG GTCACTGGGC TGTGGTGAGA GAAGGCCTCA CGAACCCTTG GATTCCGGAT 
AACTGGTCTT GGGGCGGGGT GGCTTCTGAA CACTGCCCAG TGCTAGCCGA GTTCTACACT 
GAAAAGGACT GGAGCAAGAA GGATGCCCCT CGGAACGGCA GCGGGGTGGC CTTGGAGCGA 
AGTGAAGCCA ACATCAAGCA CGAGCGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_085139.2
CDS	641..2350
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDWSKKDAPRNGSGVALERSEANIKHER

Target ORF information:

RefSeq Version	NM_030636.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030636.2

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG TTCTGCACGG AGCTAAACCA GCCGACCCTG 
CCCAACATCC GCAAGTGGAA GGGGCCCCGG GGATGCTGGA AGGCTGTTGT TGCTGAGAAG 
CCCTCGAGTC AGCTCCAGAA GGGAGCTGGG TATGCAGGAT TCCTATGGGA CGCGGCTGCC 
GGCATGGAGC TGAGAGACGC GGGTTCACAG GAGAGCTCGC CAAGCAACGG GCACGGGAAG 
CTGGCGGGCC CCAGCCCATA CCTCGGGAGG TTCAAGGTGG GAAGTCACGA CCTGACCCTT 
GTTAACCTTC ACCTGGCAGC CCTGACCCTC CTGGGGAGCG AGAATCCCAG CAAGAATCAC 
AGTGATGGCC ACCGGTTGGC GAGCTTTGCA CAGACCCTAC AGGAAACCCT GAAAGGAGAA 
AAGGATGTCA TTATCTTAGG GGATTTTGGC CAAGGGCCAG ACAGCAATGA CTATGATATC 
CTGAGGAAAG AAAAGTTCCA CCACCTGATC CCCGCGCACA CCTTCACCAA CATCAGCACC 
AAGAACCCTC AAGGCTCGAA GTCTCTGGAC AACATCTGGA TCAGTAAAAG CTTAAAGAAG 
GTTTTCACAG GTCACTGGGC TGTGGTGAGA GAAGGCCTCA CGAACCCTTG GATTCCGGAT 
AACTGGTCTT GGGGCGGGGT GGCTTCTGAA CACTGCCCAG TGCTAGCCGA GTTCTACACT 
GAAAAGGACT GGAGCAAGAA GGATGCCCCT CGGAACGGCA GCGGGGTGGC CTTGGAGCGA 
AGTGAAGCCA ACATCAAGCA CGAGCGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EEPD1 ( NM_030636.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_085139.2 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.

Price & Availability↑

CloneID	OHu04472
Clone ID Related Accession (Same CDS sequence)	NM_030636.2 , NM_030636.3
Accession Version	NM_030636.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN998549.1, AK027386.1 and AC007327.1. On Nov 22, 2018 this sequence version replaced NM_030636.2. ##Evidence-Data-START## Transcript exon combination :: AK027386.1, AB051493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000242108.9/ ENSP00000242108.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG TTCTGCACGG AGCTAAACCA GCCGACCCTG 
CCCAACATCC GCAAGTGGAA GGGGCCCCGG GGATGCTGGA AGGCTGTTGT TGCTGAGAAG 
CCCTCGAGTC AGCTCCAGAA GGGAGCTGGG TATGCAGGAT TCCTATGGGA CGCGGCTGCC 
GGCATGGAGC TGAGAGACGC GGGTTCACAG GAGAGCTCGC CAAGCAACGG GCACGGGAAG 
CTGGCGGGCC CCAGCCCATA CCTCGGGAGG TTCAAGGTGG GAAGTCACGA CCTGACCCTT 
GTTAACCTTC ACCTGGCAGC CCTGACCCTC CTGGGGAGCG AGAATCCCAG CAAGAATCAC 
AGTGATGGCC ACCGGTTGGC GAGCTTTGCA CAGACCCTAC AGGAAACCCT GAAAGGAGAA 
AAGGATGTCA TTATCTTAGG GGATTTTGGC CAAGGGCCAG ACAGCAATGA CTATGATATC 
CTGAGGAAAG AAAAGTTCCA CCACCTGATC CCCGCGCACA CCTTCACCAA CATCAGCACC 
AAGAACCCTC AAGGCTCGAA GTCTCTGGAC AACATCTGGA TCAGTAAAAG CTTAAAGAAG 
GTTTTCACAG GTCACTGGGC TGTGGTGAGA GAAGGCCTCA CGAACCCTTG GATTCCGGAT 
AACTGGTCTT GGGGCGGGGT GGCTTCTGAA CACTGCCCAG TGCTAGCCGA GTTCTACACT 
GAAAAGGACT GGAGCAAGAA GGATGCCCCT CGGAACGGCA GCGGGGTGGC CTTGGAGCGA 
AGTGAAGCCA ACATCAAGCA CGAGCGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_085139.2
CDS	614..2323
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDWSKKDAPRNGSGVALERSEANIKHER

Target ORF information:

RefSeq Version	NM_030636.3
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030636.3

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG TTCTGCACGG AGCTAAACCA GCCGACCCTG 
CCCAACATCC GCAAGTGGAA GGGGCCCCGG GGATGCTGGA AGGCTGTTGT TGCTGAGAAG 
CCCTCGAGTC AGCTCCAGAA GGGAGCTGGG TATGCAGGAT TCCTATGGGA CGCGGCTGCC 
GGCATGGAGC TGAGAGACGC GGGTTCACAG GAGAGCTCGC CAAGCAACGG GCACGGGAAG 
CTGGCGGGCC CCAGCCCATA CCTCGGGAGG TTCAAGGTGG GAAGTCACGA CCTGACCCTT 
GTTAACCTTC ACCTGGCAGC CCTGACCCTC CTGGGGAGCG AGAATCCCAG CAAGAATCAC 
AGTGATGGCC ACCGGTTGGC GAGCTTTGCA CAGACCCTAC AGGAAACCCT GAAAGGAGAA 
AAGGATGTCA TTATCTTAGG GGATTTTGGC CAAGGGCCAG ACAGCAATGA CTATGATATC 
CTGAGGAAAG AAAAGTTCCA CCACCTGATC CCCGCGCACA CCTTCACCAA CATCAGCACC 
AAGAACCCTC AAGGCTCGAA GTCTCTGGAC AACATCTGGA TCAGTAAAAG CTTAAAGAAG 
GTTTTCACAG GTCACTGGGC TGTGGTGAGA GAAGGCCTCA CGAACCCTTG GATTCCGGAT 
AACTGGTCTT GGGGCGGGGT GGCTTCTGAA CACTGCCCAG TGCTAGCCGA GTTCTACACT 
GAAAAGGACT GGAGCAAGAA GGATGCCCCT CGGAACGGCA GCGGGGTGGC CTTGGAGCGA 
AGTGAAGCCA ACATCAAGCA CGAGCGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EEPD1 ( XM_017012657.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868146.1 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu97524
Clone ID Related Accession (Same CDS sequence)	XM_017012657.1 , XM_017012657.2
Accession Version	XM_017012657.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGGT CTGCAGTATC ATTTCTGAAG 
TCAGGGAGAC CACCAACCCA CCAGGAGGAA CGAACAACTC CACACGCGCC GCCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868146.1
CDS	719..1678
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENRSAVSFLKSGRPPTHQEERTTPHAPPL

Target ORF information:

RefSeq Version	XM_017012657.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012657.1

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGGT CTGCAGTATC ATTTCTGAAG 
TCAGGGAGAC CACCAACCCA CCAGGAGGAA CGAACAACTC CACACGCGCC GCCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EEPD1 ( XM_017012657.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868146.1 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu97524
Clone ID Related Accession (Same CDS sequence)	XM_017012657.1 , XM_017012657.2
Accession Version	XM_017012657.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017012657.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGGT CTGCAGTATC ATTTCTGAAG 
TCAGGGAGAC CACCAACCCA CCAGGAGGAA CGAACAACTC CACACGCGCC GCCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868146.1
CDS	616..1575
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENRSAVSFLKSGRPPTHQEERTTPHAPPL

Target ORF information:

RefSeq Version	XM_017012657.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012657.2

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGGT CTGCAGTATC ATTTCTGAAG 
TCAGGGAGAC CACCAACCCA CCAGGAGGAA CGAACAACTC CACACGCGCC GCCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EEPD1 ( XM_017012658.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868147.1 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu97525
Clone ID Related Accession (Same CDS sequence)	XM_017012658.1 , XM_017012658.2
Accession Version	XM_017012658.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG GCTACTACTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868147.1
CDS	719..1666
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKATTED

Target ORF information:

RefSeq Version	XM_017012658.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012658.1

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG GCTACTACTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EEPD1 ( XM_017012658.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868147.1 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu97525
Clone ID Related Accession (Same CDS sequence)	XM_017012658.1 , XM_017012658.2
Accession Version	XM_017012658.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017012658.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG GCTACTACTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868147.1
CDS	616..1563
Translation	MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKATTED

Target ORF information:

RefSeq Version	XM_017012658.2
Organism	Homo sapiens(human)
Definition	Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 (EEPD1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012658.2

ORF Insert Sequence:

ATGGGGAGCA CCCTGGGCTG CCACCGCTCC ATCCCCAGGG ACCCCTCGGA CCTGTCCCAT 
AGCCGCAAGT TCAGCGCAGC CTGTAACTTC AGCAACATTC TAGTGAATCA GGAGCGGCTC 
AACATCAACA CTGCCACGGA GGAGGAGCTG ATGACCCTGC CTGGGGTGAC GCGTGCCGTG 
GCACGCAGCA TCGTGGAGTA CCGAGAGTAT ATCGGTGGCT TCAAGAAGGT GGAGGACCTG 
GCATTGGTCA GTGGTGTAGG CGCCACCAAG CTGGAGCAGG TCAAGTTTGA GATCTGTGTG 
AGCAGCAAGG GCAGCTCAGC GCAGCACTCT CCCAGTTCCC TGCGGCGGGA CCTGCTAGCG 
GAGCAGCAGC CTCACCACCT GGCCACAGCT GTGCCCCTCA CCCCACGTGT TAACATCAAC 
ACAGCCACCC CGGCCCAGCT CATGAGCGTG CGAGGCCTCT CGGAGAAAAT GGCCCTCAGC 
ATCGTGGACT TCCGCCGTGA GCATGGGCCC TTTCGCAGCG TTGAGGACCT AGTGAGGATG 
GATGGTATCA ATGCCGCCTT CCTGGACAGG ATCCGGCACC AGGTGTTTGC TGAGAGGTCC 
AGGCCCCCAT CCACCCACAC GAACGGGGGA CTGACCTTCA CCGCCAAGCC TCACCCGAGC 
CCCACTTCCC TGAGCCTGCA GAGTGAGGAC CTGGACCTGC CGCCAGGGGG GCCCACCCAG 
ATTATCTCCA CTCGGCCGTC CGTGGAGGCC TTTGGAGGCA CAAGGGATGG GAGGCCTGTG 
CTGAGGCTGG CCACCTGGAA CTTGCAGGGC TGTTCCGTGG AGAAGGCCAA CAACCCCGGG 
GTGCGAGAGG TGGTGTGCAT GACACTCCTG GAAAACAGCA TCAAGCTTCT AGCTGTGCAA 
GAACTGCTTG ACAGAGAGGC CTTGGAAAAG GCTACTACTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
Breast cancer research : BCR19(1)122(2017 Nov)
Hromas R,Kim HS,Sidhu G,Williamson E,Jaiswal A,Totterdale TA,Nole J,Lee SH,Nickoloff JA,Kong KY

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.
Arteriosclerosis, thrombosis, and vascular biology37(3)423-432(2017 Mar)
Nelson JK,Koenis DS,Scheij S,Cook EC,Moeton M,Santos A,Lobaccaro JA,Baron S,Zelcer N

Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.
The Journal of biological chemistry292(7)2795-2804(2017 02)
Kim HS,Nickoloff JA,Wu Y,Williamson EA,Sidhu GS,Reinert BL,Jaiswal AS,Srinivasan G,Patel B,Kong K,Burma S,Lee SH,Hromas RA

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
PLoS genetics11(12)e1005675(2015 Dec)
Wu Y,Lee SH,Williamson EA,Reinert BL,Cho JH,Xia F,Jaiswal AS,Srinivasan G,Patel B,Brantley A,Zhou D,Shao L,Pathak R,Hauer-Jensen M,Singh S,Kong K,Wu X,Kim HS,Beissbarth T,Gaedcke J,Burma S,Nickoloff JA,Hromas RA

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

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EEPD1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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