UBXN6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UBXN6
Entrez Gene ID	80700
Full Name	UBX domain protein 6
Synonyms	UBXD1,UBXDC2
General protein information	Preferred Names UBX domain protein 6 Names UBX domain-containing protein 6 CTB-50L17.16 UBX domain containing 1 UBX domain-containing 2 UBX domain-containing protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Disorder MIM:	611946

mRNA and Protein(s)

mRNA	Protein	Name
NM_025241.2	NP_079517.1	UBX domain-containing protein 6 isoform 1
NM_001171091.1	NP_001164562.1	UBX domain-containing protein 6 isoform 2
XM_017027325.1	XP_016882814.1	UBX domain-containing protein 6 isoform X1
NM_001171091.2	NP_001164562.1	UBX domain-containing protein 6 isoform 2
NM_025241.3	NP_079517.1	UBX domain-containing protein 6 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	UBXN6	XP_005633113.1
Drosophila melanogaster (fruit fly)	Gint3	NP_611356.1
Xenopus tropicalis (tropical clawed frog)	ubxn6	NP_001005818.1
Homo sapiens (human)	UBXN6	NP_079517.1
Mus musculus (house mouse)	Ubxn6	NP_077752.1
Caenorhabditis elegans (roundworm)	ubxn-6	NP_500648.2
Pan troglodytes (chimpanzee)	UBXN6	XP_001138764.1
	UBXN6	XP_001102137.1
Bos taurus (cattle)	UBXN6	NP_001039451.1
Danio rerio (zebrafish)	ubxn6	NP_001038245.1
Rattus norvegicus (Norway rat)	Ubxn6	NP_001102282.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006391	XP_316424.3
Gallus gallus (chicken)	UBXN6	XP_001232670.1

Gene Ontology
Bibliography

Related articles in PubMed

VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.
Guo X, Qi X
Biochimica et biophysica acta1863(2)552-559(2017 Feb)

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
Papadopoulos C, Kirchner P, Bug M, Grum D, Koerver L, Schulze N, Poehler R, Dressler A, Fengler S, Arhzaouy K, Lux V, Ehrmann M, Weihl CC, Meyer H
The EMBO journal36(2)135-150(2017 01)

The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97.
Trusch F, Matena A, Vuk M, Koerver L, Kn?velsrud H, Freemont PS, Meyer H, Bayer P
The Journal of biological chemistry290(49)29414-27(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Upon damage, p97 translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA, and the deubiquitinating enzyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response.
Title: VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.

UBXD1-N intercalates into the p97-ND1 interface, thereby modulating interdomain communication of p97 domains and its activity with relevance for disease pathogenesis
Title: The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97.

Data indicate that endosomal trafficking of CAV1 depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP-UBXD1.
Title: Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase.

UBXD1 modulates the trafficking of ERGIC-53-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53.
Title: Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.

Data show that expression of VCP mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 transport at the limiting membrane of enlarged endosomes in cultured cells.
Title: Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations.

The following UBXN6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UBXN6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09321	NM_025241.3 Latest version!	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$184.50-$258.30 $369.00
OHu09413	NM_001171091.2 Latest version!	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu88734	XM_017027325.1 Latest version!	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu09413	NM_001171091.1	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu09321	NM_025241.2	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$184.50-$258.30 $369.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UBXN6 ( NM_025241.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_079517.1 Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09321
Clone ID Related Accession (Same CDS sequence)	NM_025241.2 , NM_025241.3
Accession Version	NM_025241.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1326bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	UBX domain-containing protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM764980.1, BC008288.1 and BC007414.2. On Jan 13, 2010 this sequence version replaced NM_025241.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.400219.1, SRR1163655.68538.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427 [ECO:0000348] ##Evidence-Data-END##

ATGAAGAAAT TCTTTCAGGA GTTCAAGGCC GACATCAAGT TCAAGAGCGC GGGACCCGGT 
CAGAAGCTCA AAGAGTCCGT GGGGGAAAAG GCCCACAAAG AGAAGCCCAA CCAGCCAGCC 
CCCAGGCCGC CCCGCCAGGG ACCCACCAAT GAGGCACAGA TGGCAGCCGC TGCCGCCCTA 
GCCCGGCTGG AGCAGAAGCA GTCCCGGGCC TGGGGCCCCA CATCGCAGGA CACCATCCGA 
AACCAGGTGA GAAAGGAACT TCAAGCCGAA GCCACCGTCA GCGGGAGCCC CGAGGCCCCA 
GGGACCAACG TGGTATCTGA GCCCAGAGAG GAAGGCTCTG CCCACCTGGC TGTGCCTGGC 
GTGTACTTCA CCTGTCCGCT CACTGGGGCC ACCCTGAGGA AGGACCAGCG GGACGCCTGC 
ATCAAGGAGG CCATTCTCTT GCACTTCTCC ACCGACCCAG TGGCCGCCTC CATCATGAAG 
ATCTACACGT TCAACAAAGA CCAGGACCGG GTGAAGCTGG GTGTGGACAC CATTGCCAAG 
TACCTGGACA ACATCCACCT GCACCCCGAG GAGGAGAAGT ACCGGAAGAT CAAGCTGCAG 
AACAAGGTGT TTCAGGAGCG CATTAACTGC CTGGAAGGGA CCCACGAGTT TTTTGAGGCC 
ATTGGGTTCC AGAAGGTGTT GCTTCCCGCC CAGGATCAGG AGGACCCCGA GGAGTTCTAC 
GTGCTGAGCG AGACCACCTT GGCCCAGCCC CAGAGCCTGG AGAGGCACAA GGAACAGCTG 
CTGGCTGCGG AGCCCGTGCG CGCCAAGCTG GACAGGCAGC GCCGCGTCTT CCAGCCCTCG 
CCCCTGGCCT CGCAGTTCGA ACTGCCTGGG GACTTCTTCA ACCTCACAGC AGAGGAGATC 
AAGCGGGAGC AGAGGCTCAG GTCCGAGGCG GTGGAGCGGC TGAGCGTGCT GCGGACCAAG 
GCCATGCGGG AGAAGGAGGA GCAGCGGGGG CTGCGCAAGT ACAACTACAC GCTGCTGCGC 
GTGCGCCTCC CCGATGGCTG CCTCCTGCAG GGCACTTTCT ACGCTCGGGA GCGGCTGGGG 
GCGGTGTACG GGTTCGTCCG GGAGGCCCTG CAGAGCGACT GGCTGCCTTT TGAGCTGCTG 
GCCTCGGGAG GGCAGAAGCT GTCCGAGGAC GAGAACCTGG CCTTGAACGA GTGCGGGCTG 
GTGCCCTCTG CCCTCCTGAC CTTCTCGTGG GACATGGCTG TGCTGGAGGA CATCAAGGCC 
GCGGGGGCCG AGCCGGACTC CATCCTGAAA CCCGAGCTCC TGTCAGCCAT CGAGAAGCTC 
TTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079517.1
CDS	98..1423
Translation	MKKFFQEFKADIKFKSAGPGQKLKESVGEKAHKEKPNQPAPRPPRQGPTNEAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL

Target ORF information:

RefSeq Version	NM_025241.2
Organism	Homo sapiens(human)
Definition	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025241.2

ORF Insert Sequence:

ATGAAGAAAT TCTTTCAGGA GTTCAAGGCC GACATCAAGT TCAAGAGCGC GGGACCCGGT 
CAGAAGCTCA AAGAGTCCGT GGGGGAAAAG GCCCACAAAG AGAAGCCCAA CCAGCCAGCC 
CCCAGGCCGC CCCGCCAGGG ACCCACCAAT GAGGCACAGA TGGCAGCCGC TGCCGCCCTA 
GCCCGGCTGG AGCAGAAGCA GTCCCGGGCC TGGGGCCCCA CATCGCAGGA CACCATCCGA 
AACCAGGTGA GAAAGGAACT TCAAGCCGAA GCCACCGTCA GCGGGAGCCC CGAGGCCCCA 
GGGACCAACG TGGTATCTGA GCCCAGAGAG GAAGGCTCTG CCCACCTGGC TGTGCCTGGC 
GTGTACTTCA CCTGTCCGCT CACTGGGGCC ACCCTGAGGA AGGACCAGCG GGACGCCTGC 
ATCAAGGAGG CCATTCTCTT GCACTTCTCC ACCGACCCAG TGGCCGCCTC CATCATGAAG 
ATCTACACGT TCAACAAAGA CCAGGACCGG GTGAAGCTGG GTGTGGACAC CATTGCCAAG 
TACCTGGACA ACATCCACCT GCACCCCGAG GAGGAGAAGT ACCGGAAGAT CAAGCTGCAG 
AACAAGGTGT TTCAGGAGCG CATTAACTGC CTGGAAGGGA CCCACGAGTT TTTTGAGGCC 
ATTGGGTTCC AGAAGGTGTT GCTTCCCGCC CAGGATCAGG AGGACCCCGA GGAGTTCTAC 
GTGCTGAGCG AGACCACCTT GGCCCAGCCC CAGAGCCTGG AGAGGCACAA GGAACAGCTG 
CTGGCTGCGG AGCCCGTGCG CGCCAAGCTG GACAGGCAGC GCCGCGTCTT CCAGCCCTCG 
CCCCTGGCCT CGCAGTTCGA ACTGCCTGGG GACTTCTTCA ACCTCACAGC AGAGGAGATC 
AAGCGGGAGC AGAGGCTCAG GTCCGAGGCG GTGGAGCGGC TGAGCGTGCT GCGGACCAAG 
GCCATGCGGG AGAAGGAGGA GCAGCGGGGG CTGCGCAAGT ACAACTACAC GCTGCTGCGC 
GTGCGCCTCC CCGATGGCTG CCTCCTGCAG GGCACTTTCT ACGCTCGGGA GCGGCTGGGG 
GCGGTGTACG GGTTCGTCCG GGAGGCCCTG CAGAGCGACT GGCTGCCTTT TGAGCTGCTG 
GCCTCGGGAG GGCAGAAGCT GTCCGAGGAC GAGAACCTGG CCTTGAACGA GTGCGGGCTG 
GTGCCCTCTG CCCTCCTGAC CTTCTCGTGG GACATGGCTG TGCTGGAGGA CATCAAGGCC 
GCGGGGGCCG AGCCGGACTC CATCCTGAAA CCCGAGCTCC TGTCAGCCAT CGAGAAGCTC 
TTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBXN6 ( NM_025241.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079517.1 Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09321
Clone ID Related Accession (Same CDS sequence)	NM_025241.2 , NM_025241.3
Accession Version	NM_025241.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1326bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	UBX domain-containing protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM764980.1, BC008288.1 and BC007414.2. On Nov 23, 2018 this sequence version replaced NM_025241.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.278027.1, SRR1163655.68538.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301281.11/ ENSP00000301281.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGAAAT TCTTTCAGGA GTTCAAGGCC GACATCAAGT TCAAGAGCGC GGGACCCGGT 
CAGAAGCTCA AAGAGTCCGT GGGGGAAAAG GCCCACAAAG AGAAGCCCAA CCAGCCAGCC 
CCCAGGCCGC CCCGCCAGGG ACCCACCAAT GAGGCACAGA TGGCAGCCGC TGCCGCCCTA 
GCCCGGCTGG AGCAGAAGCA GTCCCGGGCC TGGGGCCCCA CATCGCAGGA CACCATCCGA 
AACCAGGTGA GAAAGGAACT TCAAGCCGAA GCCACCGTCA GCGGGAGCCC CGAGGCCCCA 
GGGACCAACG TGGTATCTGA GCCCAGAGAG GAAGGCTCTG CCCACCTGGC TGTGCCTGGC 
GTGTACTTCA CCTGTCCGCT CACTGGGGCC ACCCTGAGGA AGGACCAGCG GGACGCCTGC 
ATCAAGGAGG CCATTCTCTT GCACTTCTCC ACCGACCCAG TGGCCGCCTC CATCATGAAG 
ATCTACACGT TCAACAAAGA CCAGGACCGG GTGAAGCTGG GTGTGGACAC CATTGCCAAG 
TACCTGGACA ACATCCACCT GCACCCCGAG GAGGAGAAGT ACCGGAAGAT CAAGCTGCAG 
AACAAGGTGT TTCAGGAGCG CATTAACTGC CTGGAAGGGA CCCACGAGTT TTTTGAGGCC 
ATTGGGTTCC AGAAGGTGTT GCTTCCCGCC CAGGATCAGG AGGACCCCGA GGAGTTCTAC 
GTGCTGAGCG AGACCACCTT GGCCCAGCCC CAGAGCCTGG AGAGGCACAA GGAACAGCTG 
CTGGCTGCGG AGCCCGTGCG CGCCAAGCTG GACAGGCAGC GCCGCGTCTT CCAGCCCTCG 
CCCCTGGCCT CGCAGTTCGA ACTGCCTGGG GACTTCTTCA ACCTCACAGC AGAGGAGATC 
AAGCGGGAGC AGAGGCTCAG GTCCGAGGCG GTGGAGCGGC TGAGCGTGCT GCGGACCAAG 
GCCATGCGGG AGAAGGAGGA GCAGCGGGGG CTGCGCAAGT ACAACTACAC GCTGCTGCGC 
GTGCGCCTCC CCGATGGCTG CCTCCTGCAG GGCACTTTCT ACGCTCGGGA GCGGCTGGGG 
GCGGTGTACG GGTTCGTCCG GGAGGCCCTG CAGAGCGACT GGCTGCCTTT TGAGCTGCTG 
GCCTCGGGAG GGCAGAAGCT GTCCGAGGAC GAGAACCTGG CCTTGAACGA GTGCGGGCTG 
GTGCCCTCTG CCCTCCTGAC CTTCTCGTGG GACATGGCTG TGCTGGAGGA CATCAAGGCC 
GCGGGGGCCG AGCCGGACTC CATCCTGAAA CCCGAGCTCC TGTCAGCCAT CGAGAAGCTC 
TTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079517.1
CDS	98..1423
Translation	MKKFFQEFKADIKFKSAGPGQKLKESVGEKAHKEKPNQPAPRPPRQGPTNEAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL

Target ORF information:

RefSeq Version	NM_025241.3
Organism	Homo sapiens(human)
Definition	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025241.3

ORF Insert Sequence:

ATGAAGAAAT TCTTTCAGGA GTTCAAGGCC GACATCAAGT TCAAGAGCGC GGGACCCGGT 
CAGAAGCTCA AAGAGTCCGT GGGGGAAAAG GCCCACAAAG AGAAGCCCAA CCAGCCAGCC 
CCCAGGCCGC CCCGCCAGGG ACCCACCAAT GAGGCACAGA TGGCAGCCGC TGCCGCCCTA 
GCCCGGCTGG AGCAGAAGCA GTCCCGGGCC TGGGGCCCCA CATCGCAGGA CACCATCCGA 
AACCAGGTGA GAAAGGAACT TCAAGCCGAA GCCACCGTCA GCGGGAGCCC CGAGGCCCCA 
GGGACCAACG TGGTATCTGA GCCCAGAGAG GAAGGCTCTG CCCACCTGGC TGTGCCTGGC 
GTGTACTTCA CCTGTCCGCT CACTGGGGCC ACCCTGAGGA AGGACCAGCG GGACGCCTGC 
ATCAAGGAGG CCATTCTCTT GCACTTCTCC ACCGACCCAG TGGCCGCCTC CATCATGAAG 
ATCTACACGT TCAACAAAGA CCAGGACCGG GTGAAGCTGG GTGTGGACAC CATTGCCAAG 
TACCTGGACA ACATCCACCT GCACCCCGAG GAGGAGAAGT ACCGGAAGAT CAAGCTGCAG 
AACAAGGTGT TTCAGGAGCG CATTAACTGC CTGGAAGGGA CCCACGAGTT TTTTGAGGCC 
ATTGGGTTCC AGAAGGTGTT GCTTCCCGCC CAGGATCAGG AGGACCCCGA GGAGTTCTAC 
GTGCTGAGCG AGACCACCTT GGCCCAGCCC CAGAGCCTGG AGAGGCACAA GGAACAGCTG 
CTGGCTGCGG AGCCCGTGCG CGCCAAGCTG GACAGGCAGC GCCGCGTCTT CCAGCCCTCG 
CCCCTGGCCT CGCAGTTCGA ACTGCCTGGG GACTTCTTCA ACCTCACAGC AGAGGAGATC 
AAGCGGGAGC AGAGGCTCAG GTCCGAGGCG GTGGAGCGGC TGAGCGTGCT GCGGACCAAG 
GCCATGCGGG AGAAGGAGGA GCAGCGGGGG CTGCGCAAGT ACAACTACAC GCTGCTGCGC 
GTGCGCCTCC CCGATGGCTG CCTCCTGCAG GGCACTTTCT ACGCTCGGGA GCGGCTGGGG 
GCGGTGTACG GGTTCGTCCG GGAGGCCCTG CAGAGCGACT GGCTGCCTTT TGAGCTGCTG 
GCCTCGGGAG GGCAGAAGCT GTCCGAGGAC GAGAACCTGG CCTTGAACGA GTGCGGGCTG 
GTGCCCTCTG CCCTCCTGAC CTTCTCGTGG GACATGGCTG TGCTGGAGGA CATCAAGGCC 
GCGGGGGCCG AGCCGGACTC CATCCTGAAA CCCGAGCTCC TGTCAGCCAT CGAGAAGCTC 
TTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBXN6 ( NM_001171091.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001164562.1 Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09413
Clone ID Related Accession (Same CDS sequence)	NM_001171091.1 , NM_001171091.2
Accession Version	NM_001171091.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	UBX domain-containing protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008288.1, AF272894.1 and BC007414.2. Transcript Variant: This variant (2) has an alternate 5' exon, resulting in a downstream in-frame AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter than isoform 1 at the N-terminus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008288.1, AF272894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCG CTGCCGCCCT AGCCCGGCTG GAGCAGAAGC AGTCCCGGGC CTGGGGCCCC 
ACATCGCAGG ACACCATCCG AAACCAGGTG AGAAAGGAAC TTCAAGCCGA AGCCACCGTC 
AGCGGGAGCC CCGAGGCCCC AGGGACCAAC GTGGTATCTG AGCCCAGAGA GGAAGGCTCT 
GCCCACCTGG CTGTGCCTGG CGTGTACTTC ACCTGTCCGC TCACTGGGGC CACCCTGAGG 
AAGGACCAGC GGGACGCCTG CATCAAGGAG GCCATTCTCT TGCACTTCTC CACCGACCCA 
GTGGCCGCCT CCATCATGAA GATCTACACG TTCAACAAAG ACCAGGACCG GGTGAAGCTG 
GGTGTGGACA CCATTGCCAA GTACCTGGAC AACATCCACC TGCACCCCGA GGAGGAGAAG 
TACCGGAAGA TCAAGCTGCA GAACAAGGTG TTTCAGGAGC GCATTAACTG CCTGGAAGGG 
ACCCACGAGT TTTTTGAGGC CATTGGGTTC CAGAAGGTGT TGCTTCCCGC CCAGGATCAG 
GAGGACCCCG AGGAGTTCTA CGTGCTGAGC GAGACCACCT TGGCCCAGCC CCAGAGCCTG 
GAGAGGCACA AGGAACAGCT GCTGGCTGCG GAGCCCGTGC GCGCCAAGCT GGACAGGCAG 
CGCCGCGTCT TCCAGCCCTC GCCCCTGGCC TCGCAGTTCG AACTGCCTGG GGACTTCTTC 
AACCTCACAG CAGAGGAGAT CAAGCGGGAG CAGAGGCTCA GGTCCGAGGC GGTGGAGCGG 
CTGAGCGTGC TGCGGACCAA GGCCATGCGG GAGAAGGAGG AGCAGCGGGG GCTGCGCAAG 
TACAACTACA CGCTGCTGCG CGTGCGCCTC CCCGATGGCT GCCTCCTGCA GGGCACTTTC 
TACGCTCGGG AGCGGCTGGG GGCGGTGTAC GGGTTCGTCC GGGAGGCCCT GCAGAGCGAC 
TGGCTGCCTT TTGAGCTGCT GGCCTCGGGA GGGCAGAAGC TGTCCGAGGA CGAGAACCTG 
GCCTTGAACG AGTGCGGGCT GGTGCCCTCT GCCCTCCTGA CCTTCTCGTG GGACATGGCT 
GTGCTGGAGG ACATCAAGGC CGCGGGGGCC GAGCCGGACT CCATCCTGAA ACCCGAGCTC 
CTGTCAGCCA TCGAGAAGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001164562.1
CDS	155..1321
Translation	MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL

Target ORF information:

RefSeq Version	NM_001171091.1
Organism	Homo sapiens(human)
Definition	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001171091.1

ORF Insert Sequence:

ATGGCAGCCG CTGCCGCCCT AGCCCGGCTG GAGCAGAAGC AGTCCCGGGC CTGGGGCCCC 
ACATCGCAGG ACACCATCCG AAACCAGGTG AGAAAGGAAC TTCAAGCCGA AGCCACCGTC 
AGCGGGAGCC CCGAGGCCCC AGGGACCAAC GTGGTATCTG AGCCCAGAGA GGAAGGCTCT 
GCCCACCTGG CTGTGCCTGG CGTGTACTTC ACCTGTCCGC TCACTGGGGC CACCCTGAGG 
AAGGACCAGC GGGACGCCTG CATCAAGGAG GCCATTCTCT TGCACTTCTC CACCGACCCA 
GTGGCCGCCT CCATCATGAA GATCTACACG TTCAACAAAG ACCAGGACCG GGTGAAGCTG 
GGTGTGGACA CCATTGCCAA GTACCTGGAC AACATCCACC TGCACCCCGA GGAGGAGAAG 
TACCGGAAGA TCAAGCTGCA GAACAAGGTG TTTCAGGAGC GCATTAACTG CCTGGAAGGG 
ACCCACGAGT TTTTTGAGGC CATTGGGTTC CAGAAGGTGT TGCTTCCCGC CCAGGATCAG 
GAGGACCCCG AGGAGTTCTA CGTGCTGAGC GAGACCACCT TGGCCCAGCC CCAGAGCCTG 
GAGAGGCACA AGGAACAGCT GCTGGCTGCG GAGCCCGTGC GCGCCAAGCT GGACAGGCAG 
CGCCGCGTCT TCCAGCCCTC GCCCCTGGCC TCGCAGTTCG AACTGCCTGG GGACTTCTTC 
AACCTCACAG CAGAGGAGAT CAAGCGGGAG CAGAGGCTCA GGTCCGAGGC GGTGGAGCGG 
CTGAGCGTGC TGCGGACCAA GGCCATGCGG GAGAAGGAGG AGCAGCGGGG GCTGCGCAAG 
TACAACTACA CGCTGCTGCG CGTGCGCCTC CCCGATGGCT GCCTCCTGCA GGGCACTTTC 
TACGCTCGGG AGCGGCTGGG GGCGGTGTAC GGGTTCGTCC GGGAGGCCCT GCAGAGCGAC 
TGGCTGCCTT TTGAGCTGCT GGCCTCGGGA GGGCAGAAGC TGTCCGAGGA CGAGAACCTG 
GCCTTGAACG AGTGCGGGCT GGTGCCCTCT GCCCTCCTGA CCTTCTCGTG GGACATGGCT 
GTGCTGGAGG ACATCAAGGC CGCGGGGGCC GAGCCGGACT CCATCCTGAA ACCCGAGCTC 
CTGTCAGCCA TCGAGAAGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBXN6 ( NM_001171091.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001164562.1 Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.

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CloneID	OHu09413
Clone ID Related Accession (Same CDS sequence)	NM_001171091.1 , NM_001171091.2
Accession Version	NM_001171091.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	UBX domain-containing protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC011498.7, BC008288.1, AF272894.1 and BC007414.2. On Jun 1, 2019 this sequence version replaced NM_001171091.1. Transcript Variant: This variant (2) has an alternate 5' exon, resulting in a downstream in-frame AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter than isoform 1 at the N-terminus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF272894.1, BC008288.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCG CTGCCGCCCT AGCCCGGCTG GAGCAGAAGC AGTCCCGGGC CTGGGGCCCC 
ACATCGCAGG ACACCATCCG AAACCAGGTG AGAAAGGAAC TTCAAGCCGA AGCCACCGTC 
AGCGGGAGCC CCGAGGCCCC AGGGACCAAC GTGGTATCTG AGCCCAGAGA GGAAGGCTCT 
GCCCACCTGG CTGTGCCTGG CGTGTACTTC ACCTGTCCGC TCACTGGGGC CACCCTGAGG 
AAGGACCAGC GGGACGCCTG CATCAAGGAG GCCATTCTCT TGCACTTCTC CACCGACCCA 
GTGGCCGCCT CCATCATGAA GATCTACACG TTCAACAAAG ACCAGGACCG GGTGAAGCTG 
GGTGTGGACA CCATTGCCAA GTACCTGGAC AACATCCACC TGCACCCCGA GGAGGAGAAG 
TACCGGAAGA TCAAGCTGCA GAACAAGGTG TTTCAGGAGC GCATTAACTG CCTGGAAGGG 
ACCCACGAGT TTTTTGAGGC CATTGGGTTC CAGAAGGTGT TGCTTCCCGC CCAGGATCAG 
GAGGACCCCG AGGAGTTCTA CGTGCTGAGC GAGACCACCT TGGCCCAGCC CCAGAGCCTG 
GAGAGGCACA AGGAACAGCT GCTGGCTGCG GAGCCCGTGC GCGCCAAGCT GGACAGGCAG 
CGCCGCGTCT TCCAGCCCTC GCCCCTGGCC TCGCAGTTCG AACTGCCTGG GGACTTCTTC 
AACCTCACAG CAGAGGAGAT CAAGCGGGAG CAGAGGCTCA GGTCCGAGGC GGTGGAGCGG 
CTGAGCGTGC TGCGGACCAA GGCCATGCGG GAGAAGGAGG AGCAGCGGGG GCTGCGCAAG 
TACAACTACA CGCTGCTGCG CGTGCGCCTC CCCGATGGCT GCCTCCTGCA GGGCACTTTC 
TACGCTCGGG AGCGGCTGGG GGCGGTGTAC GGGTTCGTCC GGGAGGCCCT GCAGAGCGAC 
TGGCTGCCTT TTGAGCTGCT GGCCTCGGGA GGGCAGAAGC TGTCCGAGGA CGAGAACCTG 
GCCTTGAACG AGTGCGGGCT GGTGCCCTCT GCCCTCCTGA CCTTCTCGTG GGACATGGCT 
GTGCTGGAGG ACATCAAGGC CGCGGGGGCC GAGCCGGACT CCATCCTGAA ACCCGAGCTC 
CTGTCAGCCA TCGAGAAGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001164562.1
CDS	158..1324
Translation	MAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL

Target ORF information:

RefSeq Version	NM_001171091.2
Organism	Homo sapiens(human)
Definition	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001171091.2

ORF Insert Sequence:

ATGGCAGCCG CTGCCGCCCT AGCCCGGCTG GAGCAGAAGC AGTCCCGGGC CTGGGGCCCC 
ACATCGCAGG ACACCATCCG AAACCAGGTG AGAAAGGAAC TTCAAGCCGA AGCCACCGTC 
AGCGGGAGCC CCGAGGCCCC AGGGACCAAC GTGGTATCTG AGCCCAGAGA GGAAGGCTCT 
GCCCACCTGG CTGTGCCTGG CGTGTACTTC ACCTGTCCGC TCACTGGGGC CACCCTGAGG 
AAGGACCAGC GGGACGCCTG CATCAAGGAG GCCATTCTCT TGCACTTCTC CACCGACCCA 
GTGGCCGCCT CCATCATGAA GATCTACACG TTCAACAAAG ACCAGGACCG GGTGAAGCTG 
GGTGTGGACA CCATTGCCAA GTACCTGGAC AACATCCACC TGCACCCCGA GGAGGAGAAG 
TACCGGAAGA TCAAGCTGCA GAACAAGGTG TTTCAGGAGC GCATTAACTG CCTGGAAGGG 
ACCCACGAGT TTTTTGAGGC CATTGGGTTC CAGAAGGTGT TGCTTCCCGC CCAGGATCAG 
GAGGACCCCG AGGAGTTCTA CGTGCTGAGC GAGACCACCT TGGCCCAGCC CCAGAGCCTG 
GAGAGGCACA AGGAACAGCT GCTGGCTGCG GAGCCCGTGC GCGCCAAGCT GGACAGGCAG 
CGCCGCGTCT TCCAGCCCTC GCCCCTGGCC TCGCAGTTCG AACTGCCTGG GGACTTCTTC 
AACCTCACAG CAGAGGAGAT CAAGCGGGAG CAGAGGCTCA GGTCCGAGGC GGTGGAGCGG 
CTGAGCGTGC TGCGGACCAA GGCCATGCGG GAGAAGGAGG AGCAGCGGGG GCTGCGCAAG 
TACAACTACA CGCTGCTGCG CGTGCGCCTC CCCGATGGCT GCCTCCTGCA GGGCACTTTC 
TACGCTCGGG AGCGGCTGGG GGCGGTGTAC GGGTTCGTCC GGGAGGCCCT GCAGAGCGAC 
TGGCTGCCTT TTGAGCTGCT GGCCTCGGGA GGGCAGAAGC TGTCCGAGGA CGAGAACCTG 
GCCTTGAACG AGTGCGGGCT GGTGCCCTCT GCCCTCCTGA CCTTCTCGTG GGACATGGCT 
GTGCTGGAGG ACATCAAGGC CGCGGGGGCC GAGCCGGACT CCATCCTGAA ACCCGAGCTC 
CTGTCAGCCA TCGAGAAGCT CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBXN6 ( XM_017027325.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882814.1 Homo sapiens UBX domain protein 6 (UBXN6), transcript variant X1, mRNA.

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CloneID	OHu88734
Clone ID Related Accession (Same CDS sequence)	XM_017027325.1
Accession Version	XM_017027325.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	UBX domain-containing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCTGTC TCCAATCGAG AGGTGCACTC GTCGCCCTGG CAACGGAGTC CGGAAGAACC 
ACAGAGACGC GGCTCCAGCG TACAGAGCGG CCGCCCTGGG CCAGCAAGGC ACCGAGCGCT 
AGAGAGGCAC GTCTAGTCGA TTGTCACGTG GCAGGCCAGG GGAAGGCGGG ACTTCCGGCG 
GCGAGGGAAA AGGCCCACAA AGAGAAGCCC AACCAGCCAG CCCCCAGGCC GCCCCGCCAG 
GGACCCACCA ATGAGGCACA GATGGCAGCC GCTGCCGCCC TAGCCCGGCT GGAGCAGAAG 
CAGTCCCGGG CCTGGGGCCC CACATCGCAG GACACCATCC GAAACCAGGT GAGAAAGGAA 
CTTCAAGCCG AAGCCACCGT CAGCGGGAGC CCCGAGGCCC CAGGGACCAA CGTGGTATCT 
GAGCCCAGAG AGGAAGGCTC TGCCCACCTG GCTGTGCCTG GCGTGTACTT CACCTGTCCG 
CTCACTGGGG CCACCCTGAG GAAGGACCAG CGGGACGCCT GCATCAAGGA GGCCATTCTC 
TTGCACTTCT CCACCGACCC AGTGGCCGCC TCCATCATGA AGATCTACAC GTTCAACAAA 
GACCAGGACC GGGTGAAGCT GGGTGTGGAC ACCATTGCCA AGTACCTGGA CAACATCCAC 
CTGCACCCCG AGGAGGAGAA GTACCGGAAG ATCAAGCTGC AGAACAAGGT GTTTCAGGAG 
CGCATTAACT GCCTGGAAGG GACCCACGAG TTTTTTGAGG CCATTGGGTT CCAGAAGGTG 
TTGCTTCCCG CCCAGGATCA GGAGGACCCC GAGGAGTTCT ACGTGCTGAG CGAGACCACC 
TTGGCCCAGC CCCAGAGCCT GGAGAGGCAC AAGGAACAGC TGCTGGCTGC GGAGCCCGTG 
CGCGCCAAGC TGGACAGGCA GCGCCGCGTC TTCCAGCCCT CGCCCCTGGC CTCGCAGTTC 
GAACTGCCTG GGGACTTCTT CAACCTCACA GCAGAGGAGA TCAAGCGGGA GCAGAGGCTC 
AGGTCCGAGG CGGTGGAGCG GCTGAGCGTG CTGCGGACCA AGGCCATGCG GGAGAAGGAG 
GAGCAGCGGG GGCTGCGCAA GTACAACTAC ACGCTGCTGC GCGTGCGCCT CCCCGATGGC 
TGCCTCCTGC AGGGCACTTT CTACGCTCGG GAGCGGCTGG GGGCGGTGTA CGGGTTCGTC 
CGGGAGGCCC TGCAGAGCGA CTGGCTGCCT TTTGAGCTGC TGGCCTCGGG AGGGCAGAAG 
CTGTCCGAGG ACGAGAACCT GGCCTTGAAC GAGTGCGGGC TGGTGCCCTC TGCCCTCCTG 
ACCTTCTCGT GGGACATGGC TGTGCTGGAG GACATCAAGG CCGCGGGGGC CGAGCCGGAC 
TCCATCCTGA AACCCGAGCT CCTGTCAGCC ATCGAGAAGC TCTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882814.1
CDS	427..1854
Translation	MPCLQSRGALVALATESGRTTETRLQRTERPPWASKAPSAREARLVDCHVAGQGKAGLPAAREKAHKEKPNQPAPRPPRQGPTNEAQMAAAAALARLEQKQSRAWGPTSQDTIRNQVRKELQAEATVSGSPEAPGTNVVSEPREEGSAHLAVPGVYFTCPLTGATLRKDQRDACIKEAILLHFSTDPVAASIMKIYTFNKDQDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQKVLLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQFELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDGCLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQKLSEDENLALNECGLVPSALLTFSWDMAVLEDIKAAGAEPDSILKPELLSAIEKLL

Target ORF information:

RefSeq Version	XM_017027325.1
Organism	Homo sapiens(human)
Definition	Homo sapiens UBX domain protein 6 (UBXN6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027325.1

ORF Insert Sequence:

ATGCCCTGTC TCCAATCGAG AGGTGCACTC GTCGCCCTGG CAACGGAGTC CGGAAGAACC 
ACAGAGACGC GGCTCCAGCG TACAGAGCGG CCGCCCTGGG CCAGCAAGGC ACCGAGCGCT 
AGAGAGGCAC GTCTAGTCGA TTGTCACGTG GCAGGCCAGG GGAAGGCGGG ACTTCCGGCG 
GCGAGGGAAA AGGCCCACAA AGAGAAGCCC AACCAGCCAG CCCCCAGGCC GCCCCGCCAG 
GGACCCACCA ATGAGGCACA GATGGCAGCC GCTGCCGCCC TAGCCCGGCT GGAGCAGAAG 
CAGTCCCGGG CCTGGGGCCC CACATCGCAG GACACCATCC GAAACCAGGT GAGAAAGGAA 
CTTCAAGCCG AAGCCACCGT CAGCGGGAGC CCCGAGGCCC CAGGGACCAA CGTGGTATCT 
GAGCCCAGAG AGGAAGGCTC TGCCCACCTG GCTGTGCCTG GCGTGTACTT CACCTGTCCG 
CTCACTGGGG CCACCCTGAG GAAGGACCAG CGGGACGCCT GCATCAAGGA GGCCATTCTC 
TTGCACTTCT CCACCGACCC AGTGGCCGCC TCCATCATGA AGATCTACAC GTTCAACAAA 
GACCAGGACC GGGTGAAGCT GGGTGTGGAC ACCATTGCCA AGTACCTGGA CAACATCCAC 
CTGCACCCCG AGGAGGAGAA GTACCGGAAG ATCAAGCTGC AGAACAAGGT GTTTCAGGAG 
CGCATTAACT GCCTGGAAGG GACCCACGAG TTTTTTGAGG CCATTGGGTT CCAGAAGGTG 
TTGCTTCCCG CCCAGGATCA GGAGGACCCC GAGGAGTTCT ACGTGCTGAG CGAGACCACC 
TTGGCCCAGC CCCAGAGCCT GGAGAGGCAC AAGGAACAGC TGCTGGCTGC GGAGCCCGTG 
CGCGCCAAGC TGGACAGGCA GCGCCGCGTC TTCCAGCCCT CGCCCCTGGC CTCGCAGTTC 
GAACTGCCTG GGGACTTCTT CAACCTCACA GCAGAGGAGA TCAAGCGGGA GCAGAGGCTC 
AGGTCCGAGG CGGTGGAGCG GCTGAGCGTG CTGCGGACCA AGGCCATGCG GGAGAAGGAG 
GAGCAGCGGG GGCTGCGCAA GTACAACTAC ACGCTGCTGC GCGTGCGCCT CCCCGATGGC 
TGCCTCCTGC AGGGCACTTT CTACGCTCGG GAGCGGCTGG GGGCGGTGTA CGGGTTCGTC 
CGGGAGGCCC TGCAGAGCGA CTGGCTGCCT TTTGAGCTGC TGGCCTCGGG AGGGCAGAAG 
CTGTCCGAGG ACGAGAACCT GGCCTTGAAC GAGTGCGGGC TGGTGCCCTC TGCCCTCCTG 
ACCTTCTCGT GGGACATGGC TGTGCTGGAG GACATCAAGG CCGCGGGGGC CGAGCCGGAC 
TCCATCCTGA AACCCGAGCT CCTGTCAGCC ATCGAGAAGC TCTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.
Biochimica et biophysica acta1863(2)552-559(2017 Feb)
Guo X,Qi X

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
The EMBO journal36(2)135-150(2017 01)
Papadopoulos C,Kirchner P,Bug M,Grum D,Koerver L,Schulze N,Poehler R,Dressler A,Fengler S,Arhzaouy K,Lux V,Ehrmann M,Weihl CC,Meyer H

The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97.
The Journal of biological chemistry290(49)29414-27(2015 Dec)
Trusch F,Matena A,Vuk M,Koerver L,Kn?velsrud H,Freemont PS,Meyer H,Bayer P

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UBXN6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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