PABPC1L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PABPC1L
Entrez Gene ID	80336
Full Name	poly(A) binding protein cytoplasmic 1 like
Synonyms	C20orf119,EPAB,PABPC1L1,dJ1069P2.3
General protein information	Preferred Names poly(A) binding protein cytoplasmic 1 like Names polyadenylate-binding protein 1-like embryonic poly(A) binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001372179.1	NP_001359108.1	polyadenylate-binding protein 1-like
NM_001124756.2	NP_001118228.1	polyadenylate-binding protein 1-like

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PABPC1L	XP_534430.2
Bos taurus (cattle)	PABPC1L	XP_002692514.2
Danio rerio (zebrafish)	pabpc1l	NP_956133.1
Eremothecium gossypii	AGOS_AGR122C	NP_986788.1
Arabidopsis thaliana (thale cress)	PAB4	NP_179916.1
Pan troglodytes (chimpanzee)	PABPC1L	XP_514668.2
Mus musculus (house mouse)	Pabpc1l	NP_001107551.1
Saccharomyces cerevisiae (baker's yeast)	PAB1	NP_011092.1
Neurospora crassa	NCU04799	XP_960425.1
Gallus gallus (chicken)	PABPC1L	XP_417367.2
Homo sapiens (human)	PABPC1L	NP_001118228.1
Rattus norvegicus (Norway rat)	Pabpc1l	XP_230831.6
Kluyveromyces lactis	KLLA0C17600g	XP_452986.1
Schizosaccharomyces pombe (fission yeast)	pabp	NP_593377.1
Magnaporthe oryzae (rice blast fungus)	MGG_09505	XP_003712237.1
Xenopus tropicalis (tropical clawed frog)	pabpc1l	NP_001005062.1

Gene Ontology
Bibliography

Related articles in PubMed

Poly(A)-binding proteins are required for translational regulation in vertebrate oocytes and early embryos.
Ozturk S, Uysal F
Reproduction, fertility, and development29(10)1890-1901(2017 Sep)

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.
Ozturk S, Sozen B, Uysal F, Bassorgun IC, Usta MF, Akkoyunlu G, Demir N
Journal of assisted reproduction and genetics33(3)335-348(2016 Mar)

Human embryonic poly(A)-binding protein (EPAB) alternative splicing is differentially regulated in human oocytes and embryos.
Guzeloglu-Kayisli O, Lalioti MD, Babayev E, Torrealday S, Karakaya C, Seli E
Molecular human reproduction20(1)59-65(2014 Jan)

Identification and characterization of human embryonic poly(A) binding protein (EPAB).
Guzeloglu-Kayisli O, Pauli S, Demir H, Lalioti MD, Sakkas D, Seli E
Molecular human reproduction14(10)581-8(2008 Oct)

Isolation of the human ePAB and ePABP2 cDNAs and analysis of the expression patterns.
Sakugawa N, Miyamoto T, Sato H, Ishikawa M, Horikawa M, Hayashi H, Ishikawa M, Sengoku K
Journal of assisted reproduction and genetics25(5)215-21(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EPAB decreased expression in in infertile men with non-obstructive azoospermia
Title: The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

Human EPAB mRNA is detected in ovaries, testes and several somatic tissues including pancreas, liver and thymus, and EPAB is the predominant poly(A) binding protein in immature (germinal vesicle) and mature (metaphase II) oocytes.
Title: Identification and characterization of human embryonic poly(A) binding protein (EPAB).

The following PABPC1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PABPC1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu32127	NM_001124756.2 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu108858	NM_001372179.1 Latest version!	Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PABPC1L ( NM_001124756.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001118228.1 Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32127
Clone ID Related Accession (Same CDS sequence)	NM_001124756.2
Accession Version	NM_001124756.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 1-like
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC418955.1, DR001377.1, EU190483.1, BX451955.2, AL109839.11, BM689138.1, BQ446831.1 and AI597906.1. On Jan 27, 2016 this sequence version replaced NM_001124756.1. Transcript Variant: This variant (1) encodes the protein. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145313 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: PMID: 18716053 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACGCCA GCGGTTCTGG CTACCCGCTT GCCTCGCTTT ACGTGGGCGA TCTGCACCCC 
GACGTGACCG AGGCCATGCT CTATGAGAAG TTCTCTCCCG CCGGCCCCAT CCTGTCCATC 
CGCGTGTGCC GCGATGTAGC CACCCGGCGC TCGCTGGGCT ACGCCTACAT CAACTTCCAG 
CAGCCCGCGG ACGCGGAGCG GGCACTGGAC ACAATGAACT TTGAGATGCT CAAAGGCCAG 
CCTATTCGCA TCATGTGGTC CCAGCGAGAC CCAGGACTTC GCAAGTCAGG TGTGGGCAAC 
ATCTTCATCA AGAACCTGGA GGACTCCATT GACAACAAGG CTTTATATGA TACCTTCTCC 
ACCTTTGGGA ACATCCTCTC TTGCAAGGTG GCGTGTGACG AGCATGGCTC CCGGGGTTTC 
GGCTTTGTCC ATTTTGAGAC CCATGAGGCC GCACAGCAGG CCATCAACAC CATGAATGGG 
ATGCTGCTGA ATGACCGCAA AGTCTTTGTG GGTCACTTCA AGTCTCGACG GGAGCGGGAG 
GCGGAGCTGG GGGCGCGGGC CCTGGAGTTC ACCAACATCT ACGTGAAGAA CCTCCCGGTG 
GATGTGGACG AGCAAGGCCT GCAGGACCTC TTCTCCCAGT TTGGGAAAAT GCTGAGTGTG 
AAGGTGATGA GGGACAACAG CGGCCACTCG CGGTGCTTTG GCTTTGTCAA CTTTGAGAAG 
CATGAGGAAG CCCAGAAGGC CGTGGTCCAT ATGAACGGGA AGGAGGTGAG CGGGCGGCTG 
CTGTACGCGG GCCGGGCCCA AAAGCGCGTG GAGCGGCAGA ATGAACTGAA GCGCAGGTTT 
GAGCAGATGA AGCAGGACCG GCTGAGGCGT TACCAGGGTG TGAACTTGTA TGTGAAGAAT 
CTGGACGACT CCATTGATGA CGACAAACTG AGGAAAGAGT TCTCTCCCTA TGGAGTAATT 
ACCAGTGCGA AGGTGATGAC AGAGGGTGGC CACAGCAAGG GGTTTGGCTT TGTGTGTTTT 
TCCTCCCCAG AAGAGGCGAC AAAGGCCGTG ACAGAGATGA ACGGGCGCAT CGTGGGCACC 
AAGCCACTCT ACGTGGCACT GGCCCAGCGC AAAGAGGAGC GGAAGGCCAT CTTGACCAAC 
CAGTACATGC AGCGCCTCTC CACCATGCGG ACCCTGAGCA ACCCCCTCCT GGGCTCCTTT 
CAGCAGCCCT CCAGCTACTT CCTGCCTGCC ATGCCCCAGC CTCCAGCCCA GGCTGCATAC 
TATGGCTGTG GCCCAGTGAC ACCCACCCAG CCTGCCCCCA GGTGGACATC CCAGCCACCT 
AGACCTTCCT GTGCCTCAAT GGTCCGGCCA CCAGTTGTGC CTCGGCGCCC CCCGGCCCAC 
ATCAGCAGTG TCAGGCAGGC CTCCACCCAG GTGCCACGCA CGGTGCCTCA TACCCAGAGA 
GTAGCCAACA TTGGTACTCA GACCACAGGA CCCAGTGGGG TAGGATGCTG TACACCAGGC 
CGGCCGCTCC TGCCGTGCAA ATGTTCCTCA GCAGCACATA GCACCTATCG GGTCCAGGAG 
CCGGCTGTGC ACATCCCAGG ACAGGAGCCC CTGACCGCGT CCATGCTGGC TGCGGCGCCC 
CTGCATGAGC AAAAGCAGAT GATTGGGGAG CGTCTCTACC CCCTTATCCA TGATGTCCAC 
ACCCAGCTGG CTGGCAAGAT CACGGGCATG CTGCTGGAGA TTGACAACTC AGAGCTGTTG 
CTCATGCTGG AGTCTCCAGA ATCCCTCCAT GCCAAGATAG ACGAGGCAGT GGCCGTGCTG 
CAGGCACACC AGGCTATGGA GCAGCCGAAG GCGTACATGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001118228.1
CDS	85..1929
Translation	MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQRVANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAMEQPKAYMH

Target ORF information:

RefSeq Version	NM_001124756.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001124756.2

ORF Insert Sequence:

ATGAACGCCA GCGGTTCTGG CTACCCGCTT GCCTCGCTTT ACGTGGGCGA TCTGCACCCC 
GACGTGACCG AGGCCATGCT CTATGAGAAG TTCTCTCCCG CCGGCCCCAT CCTGTCCATC 
CGCGTGTGCC GCGATGTAGC CACCCGGCGC TCGCTGGGCT ACGCCTACAT CAACTTCCAG 
CAGCCCGCGG ACGCGGAGCG GGCACTGGAC ACAATGAACT TTGAGATGCT CAAAGGCCAG 
CCTATTCGCA TCATGTGGTC CCAGCGAGAC CCAGGACTTC GCAAGTCAGG TGTGGGCAAC 
ATCTTCATCA AGAACCTGGA GGACTCCATT GACAACAAGG CTTTATATGA TACCTTCTCC 
ACCTTTGGGA ACATCCTCTC TTGCAAGGTG GCGTGTGACG AGCATGGCTC CCGGGGTTTC 
GGCTTTGTCC ATTTTGAGAC CCATGAGGCC GCACAGCAGG CCATCAACAC CATGAATGGG 
ATGCTGCTGA ATGACCGCAA AGTCTTTGTG GGTCACTTCA AGTCTCGACG GGAGCGGGAG 
GCGGAGCTGG GGGCGCGGGC CCTGGAGTTC ACCAACATCT ACGTGAAGAA CCTCCCGGTG 
GATGTGGACG AGCAAGGCCT GCAGGACCTC TTCTCCCAGT TTGGGAAAAT GCTGAGTGTG 
AAGGTGATGA GGGACAACAG CGGCCACTCG CGGTGCTTTG GCTTTGTCAA CTTTGAGAAG 
CATGAGGAAG CCCAGAAGGC CGTGGTCCAT ATGAACGGGA AGGAGGTGAG CGGGCGGCTG 
CTGTACGCGG GCCGGGCCCA AAAGCGCGTG GAGCGGCAGA ATGAACTGAA GCGCAGGTTT 
GAGCAGATGA AGCAGGACCG GCTGAGGCGT TACCAGGGTG TGAACTTGTA TGTGAAGAAT 
CTGGACGACT CCATTGATGA CGACAAACTG AGGAAAGAGT TCTCTCCCTA TGGAGTAATT 
ACCAGTGCGA AGGTGATGAC AGAGGGTGGC CACAGCAAGG GGTTTGGCTT TGTGTGTTTT 
TCCTCCCCAG AAGAGGCGAC AAAGGCCGTG ACAGAGATGA ACGGGCGCAT CGTGGGCACC 
AAGCCACTCT ACGTGGCACT GGCCCAGCGC AAAGAGGAGC GGAAGGCCAT CTTGACCAAC 
CAGTACATGC AGCGCCTCTC CACCATGCGG ACCCTGAGCA ACCCCCTCCT GGGCTCCTTT 
CAGCAGCCCT CCAGCTACTT CCTGCCTGCC ATGCCCCAGC CTCCAGCCCA GGCTGCATAC 
TATGGCTGTG GCCCAGTGAC ACCCACCCAG CCTGCCCCCA GGTGGACATC CCAGCCACCT 
AGACCTTCCT GTGCCTCAAT GGTCCGGCCA CCAGTTGTGC CTCGGCGCCC CCCGGCCCAC 
ATCAGCAGTG TCAGGCAGGC CTCCACCCAG GTGCCACGCA CGGTGCCTCA TACCCAGAGA 
GTAGCCAACA TTGGTACTCA GACCACAGGA CCCAGTGGGG TAGGATGCTG TACACCAGGC 
CGGCCGCTCC TGCCGTGCAA ATGTTCCTCA GCAGCACATA GCACCTATCG GGTCCAGGAG 
CCGGCTGTGC ACATCCCAGG ACAGGAGCCC CTGACCGCGT CCATGCTGGC TGCGGCGCCC 
CTGCATGAGC AAAAGCAGAT GATTGGGGAG CGTCTCTACC CCCTTATCCA TGATGTCCAC 
ACCCAGCTGG CTGGCAAGAT CACGGGCATG CTGCTGGAGA TTGACAACTC AGAGCTGTTG 
CTCATGCTGG AGTCTCCAGA ATCCCTCCAT GCCAAGATAG ACGAGGCAGT GGCCGTGCTG 
CAGGCACACC AGGCTATGGA GCAGCCGAAG GCGTACATGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PABPC1L ( NM_001372179.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001359108.1 Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu108858
Clone ID Related Accession (Same CDS sequence)	NM_001372179.1
Accession Version	NM_001372179.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein 1-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL008725.1 and AL109839.11. Transcript Variant: This variant (7) encodes the protein. This variant is abundantly expressed in human oocytes. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAACGCCA GCGGTTCTGG CTACCCGCTT GCCTCGCTTT ACGTGGGCGA TCTGCACCCC 
GACGTGACCG AGGCCATGCT CTATGAGAAG TTCTCTCCCG CCGGCCCCAT CCTGTCCATC 
CGCGTGTGCC GCGATGTAGC CACCCGGCGC TCGCTGGGCT ACGCCTACAT CAACTTCCAG 
CAGCCCGCGG ACGCGGAGCG GGCACTGGAC ACAATGAACT TTGAGATGCT CAAAGGCCAG 
CCTATTCGCA TCATGTGGTC CCAGCGAGAC CCAGGACTTC GCAAGTCAGG TGTGGGCAAC 
ATCTTCATCA AGAACCTGGA GGACTCCATT GACAACAAGG CTTTATATGA TACCTTCTCC 
ACCTTTGGGA ACATCCTCTC TTGCAAGGTG GCGTGTGACG AGCATGGCTC CCGGGGTTTC 
GGCTTTGTCC ATTTTGAGAC CCATGAGGCC GCACAGCAGG CCATCAACAC CATGAATGGG 
ATGCTGCTGA ATGACCGCAA AGTCTTTGTG GGTCACTTCA AGTCTCGACG GGAGCGGGAG 
GCGGAGCTGG GGGCGCGGGC CCTGGAGTTC ACCAACATCT ACGTGAAGAA CCTCCCGGTG 
GATGTGGACG AGCAAGGCCT GCAGGACCTC TTCTCCCAGT TTGGGAAAAT GCTGAGTGTG 
AAGGTGATGA GGGACAACAG CGGCCACTCG CGGTGCTTTG GCTTTGTCAA CTTTGAGAAG 
CATGAGGAAG CCCAGAAGGC CGTGGTCCAT ATGAACGGGA AGGAGGTGAG CGGGCGGCTG 
CTGTACGCGG GCCGGGCCCA AAAGCGCGTG GAGCGGCAGA ATGAACTGAA GCGCAGGTTT 
GAGCAGATGA AGCAGGACCG GCTGAGGCGT TACCAGGGTG TGAACTTGTA TGTGAAGAAT 
CTGGACGACT CCATTGATGA CGACAAACTG AGGAAAGAGT TCTCTCCCTA TGGAGTAATT 
ACCAGTGCGA AGGTGATGAC AGAGGGTGGC CACAGCAAGG GGTTTGGCTT TGTGTGTTTT 
TCCTCCCCAG AAGAGGCGAC AAAGGCCGTG ACAGAGATGA ACGGGCGCAT CGTGGGCACC 
AAGCCACTCT ACGTGGCACT GGCCCAGCGC AAAGAGGAGC GGAAGGCCAT CTTGACCAAC 
CAGTACATGC AGCGCCTCTC CACCATGCGG ACCCTGAGCA ACCCCCTCCT GGGCTCCTTT 
CAGCAGCCCT CCAGCTACTT CCTGCCTGCC ATGCCCCAGC CTCCAGCCCA GGCTGCATAC 
TATGGCTGTG GCCCAGTGAC ACCCACCCAG CCTGCCCCCA GGTGGACATC CCAGCCACCT 
AGACCTTCCT CTGCCTACCC TCCAGGTGCC TCAATGGTCC GGCCACCAGT TGTGCCTCGG 
CGCCCCCCGG CCCACATCAG CAGTGTCAGG CAGGCCTCCA CCCAGGTGCC ACGCACGGTG 
CCTCATACCC AGAGAGTAGC CAACATTGGT ACTCAGACCA CAGGACCCAG TGGGGTAGGA 
TGCTGTACAC CAGGCCGGCC GCTCCTGCCG TGCAAATGTT CCTCAGCAGC ACATAGCACC 
TATCGGGTCC AGGAGCCGGC TGTGCACATC CCAGGACAGG AGCCCCTGAC CGCGTCCATG 
CTGGCTGCGG CGCCCCTGCA TGAGCAAAAG CAGATGATTG GGGAGCGTCT CTACCCCCTT 
ATCCATGATG TCCACACCCA GCTGGCTGGC AAGATCACGG GCATGCTGCT GGAGATTGAC 
AACTCAGAGC TGTTGCTCAT GCTGGAGTCT CCAGAATCCC TCCATGCCAA GATAGACGAG 
GCAGTGGCCG TGCTGCAGGC ACACCAGGCT ATGGAGCAGC CGAAGGCGTA CATGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001359108.1
CDS	85..1944
Translation	MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGCGPVTPTQPAPRWTSQPPRPSSAYPPGASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQRVANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAMEQPKAYMH

Target ORF information:

RefSeq Version	NM_001372179.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein cytoplasmic 1 like (PABPC1L), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001372179.1

ORF Insert Sequence:

ATGAACGCCA GCGGTTCTGG CTACCCGCTT GCCTCGCTTT ACGTGGGCGA TCTGCACCCC 
GACGTGACCG AGGCCATGCT CTATGAGAAG TTCTCTCCCG CCGGCCCCAT CCTGTCCATC 
CGCGTGTGCC GCGATGTAGC CACCCGGCGC TCGCTGGGCT ACGCCTACAT CAACTTCCAG 
CAGCCCGCGG ACGCGGAGCG GGCACTGGAC ACAATGAACT TTGAGATGCT CAAAGGCCAG 
CCTATTCGCA TCATGTGGTC CCAGCGAGAC CCAGGACTTC GCAAGTCAGG TGTGGGCAAC 
ATCTTCATCA AGAACCTGGA GGACTCCATT GACAACAAGG CTTTATATGA TACCTTCTCC 
ACCTTTGGGA ACATCCTCTC TTGCAAGGTG GCGTGTGACG AGCATGGCTC CCGGGGTTTC 
GGCTTTGTCC ATTTTGAGAC CCATGAGGCC GCACAGCAGG CCATCAACAC CATGAATGGG 
ATGCTGCTGA ATGACCGCAA AGTCTTTGTG GGTCACTTCA AGTCTCGACG GGAGCGGGAG 
GCGGAGCTGG GGGCGCGGGC CCTGGAGTTC ACCAACATCT ACGTGAAGAA CCTCCCGGTG 
GATGTGGACG AGCAAGGCCT GCAGGACCTC TTCTCCCAGT TTGGGAAAAT GCTGAGTGTG 
AAGGTGATGA GGGACAACAG CGGCCACTCG CGGTGCTTTG GCTTTGTCAA CTTTGAGAAG 
CATGAGGAAG CCCAGAAGGC CGTGGTCCAT ATGAACGGGA AGGAGGTGAG CGGGCGGCTG 
CTGTACGCGG GCCGGGCCCA AAAGCGCGTG GAGCGGCAGA ATGAACTGAA GCGCAGGTTT 
GAGCAGATGA AGCAGGACCG GCTGAGGCGT TACCAGGGTG TGAACTTGTA TGTGAAGAAT 
CTGGACGACT CCATTGATGA CGACAAACTG AGGAAAGAGT TCTCTCCCTA TGGAGTAATT 
ACCAGTGCGA AGGTGATGAC AGAGGGTGGC CACAGCAAGG GGTTTGGCTT TGTGTGTTTT 
TCCTCCCCAG AAGAGGCGAC AAAGGCCGTG ACAGAGATGA ACGGGCGCAT CGTGGGCACC 
AAGCCACTCT ACGTGGCACT GGCCCAGCGC AAAGAGGAGC GGAAGGCCAT CTTGACCAAC 
CAGTACATGC AGCGCCTCTC CACCATGCGG ACCCTGAGCA ACCCCCTCCT GGGCTCCTTT 
CAGCAGCCCT CCAGCTACTT CCTGCCTGCC ATGCCCCAGC CTCCAGCCCA GGCTGCATAC 
TATGGCTGTG GCCCAGTGAC ACCCACCCAG CCTGCCCCCA GGTGGACATC CCAGCCACCT 
AGACCTTCCT CTGCCTACCC TCCAGGTGCC TCAATGGTCC GGCCACCAGT TGTGCCTCGG 
CGCCCCCCGG CCCACATCAG CAGTGTCAGG CAGGCCTCCA CCCAGGTGCC ACGCACGGTG 
CCTCATACCC AGAGAGTAGC CAACATTGGT ACTCAGACCA CAGGACCCAG TGGGGTAGGA 
TGCTGTACAC CAGGCCGGCC GCTCCTGCCG TGCAAATGTT CCTCAGCAGC ACATAGCACC 
TATCGGGTCC AGGAGCCGGC TGTGCACATC CCAGGACAGG AGCCCCTGAC CGCGTCCATG 
CTGGCTGCGG CGCCCCTGCA TGAGCAAAAG CAGATGATTG GGGAGCGTCT CTACCCCCTT 
ATCCATGATG TCCACACCCA GCTGGCTGGC AAGATCACGG GCATGCTGCT GGAGATTGAC 
AACTCAGAGC TGTTGCTCAT GCTGGAGTCT CCAGAATCCC TCCATGCCAA GATAGACGAG 
GCAGTGGCCG TGCTGCAGGC ACACCAGGCT ATGGAGCAGC CGAAGGCGTA CATGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Poly(A)-binding proteins are required for translational regulation in vertebrate oocytes and early embryos.
Reproduction, fertility, and development29(10)1890-1901(2017 Sep)
Ozturk S,Uysal F

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.
Journal of assisted reproduction and genetics33(3)335-348(2016 Mar)
Ozturk S,Sozen B,Uysal F,Bassorgun IC,Usta MF,Akkoyunlu G,Demir N

Human embryonic poly(A)-binding protein (EPAB) alternative splicing is differentially regulated in human oocytes and embryos.
Molecular human reproduction20(1)59-65(2014 Jan)
Guzeloglu-Kayisli O,Lalioti MD,Babayev E,Torrealday S,Karakaya C,Seli E

Identification and characterization of human embryonic poly(A) binding protein (EPAB).
Molecular human reproduction14(10)581-8(2008 Oct)
Guzeloglu-Kayisli O,Pauli S,Demir H,Lalioti MD,Sakkas D,Seli E

Isolation of the human ePAB and ePABP2 cDNAs and analysis of the expression patterns.
Journal of assisted reproduction and genetics25(5)215-21(2008 May)
Sakugawa N,Miyamoto T,Sato H,Ishikawa M,Horikawa M,Hayashi H,Ishikawa M,Sengoku K

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PABPC1L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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