DNAJC5 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DNAJC5
Entrez Gene ID	80331
Full Name	DnaJ heat shock protein family (Hsp40) member C5
Synonyms	CLN4,CLN4B,CSP,DNAJC5A,NCL,mir-941-2,mir-941-3,mir-941-4,mir-941-5
General protein information	Preferred Names DnaJ heat shock protein family (Hsp40) member C5 Names dnaJ homolog subfamily C member 5 DnaJ (Hsp40) homolog, subfamily C, member 5 ceroid-lipofuscinosis neuronal protein 4 cysteine string protein alpha
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010].
Disorder MIM:	611203
Disorder Html:	Ceroid lipofuscinosis, neuronal, 4, Parry type, 162350 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_025219.2	NP_079495.1	dnaJ homolog subfamily C member 5
XM_011529050.1	XP_011527352.1	dnaJ homolog subfamily C member 5 isoform X1
XM_011529049.1	XP_011527351.1	dnaJ homolog subfamily C member 5 isoform X1
NM_025219.3	NP_079495.1	dnaJ homolog subfamily C member 5
XM_011529048.2	XP_011527350.1	dnaJ homolog subfamily C member 5 isoform X1
XM_011529048.1	XP_011527350.1	dnaJ homolog subfamily C member 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DNAJC5	XP_530321.2
Danio rerio (zebrafish)	dnajc5ab	XP_001338363.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007620	XP_308251.4
	DNAJC5	XP_001084014.1
Canis lupus familiaris (dog)	DNAJC5	XP_005635371.1
Bos taurus (cattle)	DNAJC5	NP_776958.2
Rattus norvegicus (Norway rat)	Dnajc5	NP_077075.1
Gallus gallus (chicken)	DNAJC5	NP_001264937.1
Homo sapiens (human)	DNAJC5	NP_079495.1
Mus musculus (house mouse)	Dnajc5	NP_058055.1
Drosophila melanogaster (fruit fly)	Csp	NP_524213.1
Danio rerio (zebrafish)	dnajc5aa	NP_001002464.1

Gene Ontology
Bibliography

Related articles in PubMed

Primary fibroblasts from CSP? mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis.
Benitez BA, Sands MS
Scientific reports7(1)6332(2017 Jul)

Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch.
Patel P, Prescott GR, Burgoyne RD, Lian LY, Morgan A
Structure (London, England : 1993)24(8)1380-1386(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Phosphorylation of CSP triggers a major conformational switch that modulates its protein interactions.
Title: Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch.

In fact, DnaJC5 overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 was intact and when tau was able to associate with this chaperone.
Title: DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.

This study demonstrated that Neuronal ceroid lipofuscinosis with DNAJC5/CSPalpha mutation has PPT1 pathology and exhibit aberrant protein palmitoylation.
Title: Neuronal ceroid lipofuscinosis with DNAJC5/CSP? mutation has PPT1 pathology and exhibit aberrant protein palmitoylation.

These results suggest that the degeneration seen in the patients with AD-ANCL reported here might be a consequence of both the early effects of CSPalpha mutations at the cellular soma.
Title: Clinically early-stage CSP? mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss.

the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.
Title: Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.

The following DNAJC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DNAJC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26667	NM_025219.3 Latest version!	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26667	XM_011529049.1 Latest version!	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26667	XM_011529050.1 Latest version!	Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26667	XM_011529048.2 Latest version!	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu26667	NM_025219.2	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26667	XM_011529048.1	Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DNAJC5 ( NM_025219.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_079495.1 Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.

Price & Availability↑

CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	NM_025219.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	dnaJ homolog subfamily C member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB452738.1, BC053642.1 and CR627461.1. This sequence is a reference standard in the RefSeqGene project. On Dec 1, 2010 this sequence version replaced NM_025219.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC053642.1, AK289585.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079495.1
CDS	234..830
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	NM_025219.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025219.2

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNAJC5 ( NM_025219.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_079495.1 Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.

Price & Availability↑

CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	NM_025219.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	dnaJ homolog subfamily C member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB452738.1, BC053642.1 and CR627461.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_025219.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC053642.1, AK289585.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000360864.9/ ENSP00000354111.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079495.1
CDS	210..806
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	NM_025219.3
Organism	Homo sapiens(human)
Definition	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025219.3

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNAJC5 ( XM_011529050.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011527352.1 Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	XM_011529050.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	dnaJ homolog subfamily C member 5 isoform X1
Comment

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527352.1
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	XM_011529050.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529050.1

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNAJC5 ( XM_011529049.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011527351.1 Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	XM_011529049.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dnaJ homolog subfamily C member 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527351.1
CDS	891..1487
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	XM_011529049.1
Organism	Homo sapiens(human)
Definition	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529049.1

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNAJC5 ( XM_011529048.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011527350.1 Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	XM_011529048.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dnaJ homolog subfamily C member 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529048.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527350.1
CDS	642..1238
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	XM_011529048.2
Organism	Homo sapiens(human)
Definition	Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 (DNAJC5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529048.2

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNAJC5 ( XM_011529048.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011527350.1 Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X1, mRNA.

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CloneID	OHu26667
Clone ID Related Accession (Same CDS sequence)	NM_025219.2 , XM_011529050.1 , XM_011529049.1 , NM_025219.3 , XM_011529048.2 , XM_011529048.1
Accession Version	XM_011529048.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	dnaJ homolog subfamily C member 5 isoform X1
Comment

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527350.1
Translation	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Target ORF information:

RefSeq Version	XM_011529048.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529048.1

ORF Insert Sequence:

ATGGCAGACC AGAGACAGCG CTCACTGTCT ACCTCTGGGG AGTCATTGTA CCACGTCCTT 
GGGTTGGACA AGAACGCAAC CTCAGATGAC ATTAAAAAGT CCTATCGGAA GCTTGCCTTG 
AAATATCACC CCGACAAGAA CCCCGACAAC CCGGAGGCCG CGGACAAGTT TAAGGAGATC 
AACAACGCGC ACGCCATCCT CACGGACGCC ACAAAAAGGA ACATCTACGA CAAGTACGGC 
TCGCTGGGTC TCTACGTGGC CGAGCAGTTT GGGGAAGAGA ACGTGAACAC CTACTTCGTG 
CTGTCCAGCT GGTGGGCCAA GGCCCTGTTT GTCTTCTGCG GCCTCCTCAC GTGCTGCTAC 
TGCTGCTGCT GTCTGTGCTG CTGCTTCAAC TGCTGCTGCG GGAAGTGTAA GCCCAAGGCG 
CCTGAAGGCG AGGAGACGGA GTTCTACGTG TCCCCCGAGG ATCTGGAGGC ACAGCTGCAG 
TCTGACGAGA GGGAGGCCAC AGACACGCCG ATCGTCATAC AGCCGGCATC CGCCACCGAG 
ACCACCCAGC TCACAGCCGA CTCCCACCCC AGCTACCACA CTGACGGGTT CAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Primary fibroblasts from CSP? mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis.
Scientific reports7(1)6332(2017 Jul)
Benitez BA,Sands MS

Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch.
Structure (London, England : 1993)24(8)1380-1386(2016 08)
Patel P,Prescott GR,Burgoyne RD,Lian LY,Morgan A

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DNAJC5 cDNA ORF clone, Homo sapiens(Human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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