ITPKC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITPKC
Entrez Gene ID	80271
Full Name	inositol-trisphosphate 3-kinase C
Synonyms	IP3-3KC,IP3KC
General protein information	Preferred Names inositol-trisphosphate 3-kinase C Names inositol-trisphosphate 3-kinase C IP3 3-kinase C IP3K C InsP 3 kinase C inositol 1,4,5-trisphosphate 3-kinase C insP 3-kinase C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.[provided by RefSeq, Sep 2009].
Disorder MIM:	606476
Disorder Html:	{Kawasaki disease, susceptibility to}, 611775 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_006723404.1	XP_006723467.1	inositol-trisphosphate 3-kinase C isoform X1
NM_025194.2	NP_079470.1	inositol-trisphosphate 3-kinase C
NM_025194.3	NP_079470.1	inositol-trisphosphate 3-kinase C
XM_017027324.1	XP_016882813.1	inositol-trisphosphate 3-kinase C isoform X1
XM_017027324.2	XP_016882813.1	inositol-trisphosphate 3-kinase C isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ITPKC	NP_001069479.1
	LOC703722	XP_001092036.1
Mus musculus (house mouse)	Itpkc	NP_853624.1
Xenopus tropicalis (tropical clawed frog)	itpkc	NP_001072256.1
Homo sapiens (human)	ITPKC	NP_079470.1
Canis lupus familiaris (dog)	ITPKC	XP_855312.2
Rattus norvegicus (Norway rat)	Itpkc	NP_835195.1
Pan troglodytes (chimpanzee)	ITPKC	XP_524271.2

Gene Ontology
Bibliography

Related articles in PubMed

ITPKC and SLC11A1 Gene Polymorphisms and Gene-Gene Interactions in Korean Patients with Kawasaki Disease.
Kim KY, Bae YS, Ji W, Shin D, Kim HS, Kim DS
Yonsei medical journal59(1)119-127(2018 Jan)

Potential association between ITPKC genetic variations and Hirschsprung disease.
Kim JH, Jung SM, Shin JG, Cheong HS, Seo JM, Kim DY, Oh JT, Kim HY, Jung K, Shin HD
Molecular biology reports44(3)307-313(2017 Jul)

Inositol-Triphosphate 3-Kinase C Mediates Inflammasome Activation and Treatment Response in Kawasaki Disease.
Alphonse MP, Duong TT, Shumitzu C, Hoang TL, McCrindle BW, Franco A, Schurmans S, Philpott DJ, Hibberd ML, Burns J, Kuijpers TW, Yeung RS
Journal of immunology (Baltimore, Md. : 1950)197(9)3481-3489(2016 Nov)

The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.
Wang W, Lou J, Zhong R, Qi YQ, Shen N, Lu XZ, Wang YJ, Zhang Q, Zou L, Duan JY, Ke JT, Miao XP, Gong FQ
Scientific reports45208(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Genetic variants of ITPKC may have a potential association with HSCR (Hirschsprung disease) susceptibility and/or developmental diseases related to enteric nervous system development.
Title: Potential association between ITPKC genetic variations and Hirschsprung disease.

this study shows that the KD-associated genetic polymorphism in inositol-triphosphate 3-kinase C (ITPKC) (rs28493229) has important functional consequences, governing ITPKC protein levels and thereby intracellular calcium, which in turn regulates NLRP3 expression and production of IL-1beta and IL-18.
Title: Inositol-Triphosphate 3-Kinase C Mediates Inflammasome Activation and Treatment Response in Kawasaki Disease.

ITPKC polymorphisms are associated with Kawasaki disease.
Title: The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.

SNP rs7251246 in ITPKC is associated with the severity of Kawasaki disease
Title: Single-nucleotide polymorphism rs7251246 in ITPKC is associated with susceptibility and coronary artery lesions in Kawasaki disease.

Our results identify a novel polymorphism for renal function and highlight the importance of ITPKC as a key molecule to regulate calcium signaling.
Title: Study of the association between ITPKC genetic polymorphisms and calcium nephrolithiasis.

The following ITPKC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITPKC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18914	NM_025194.3 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu18914	XM_006723404.1 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu88733	XM_017027324.2 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu18914	NM_025194.2	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu88733	XM_017027324.1	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITPKC ( NM_025194.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_079470.1 Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.

Price & Availability↑

CloneID	OHu18914
Clone ID Related Accession (Same CDS sequence)	XM_006723404.1 , NM_025194.2 , NM_025194.3
Accession Version	NM_025194.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC060788.1. This sequence is a reference standard in the RefSeqGene project. On Dec 20, 2003 this sequence version replaced NM_025194.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060788.1, SRR1803613.31729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079470.1
CDS	34..2085
Translation	MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

Target ORF information:

RefSeq Version	NM_025194.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025194.2

ORF Insert Sequence:

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKC ( NM_025194.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079470.1 Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.

Price & Availability↑

CloneID	OHu18914
Clone ID Related Accession (Same CDS sequence)	XM_006723404.1 , NM_025194.2 , NM_025194.3
Accession Version	NM_025194.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC060788.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_025194.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060788.1, SRR1803613.31729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263370.3/ ENSP00000263370.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079470.1
CDS	25..2076
Translation	MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

Target ORF information:

RefSeq Version	NM_025194.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025194.3

ORF Insert Sequence:

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKC ( XM_006723404.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723467.1 Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu18914
Clone ID Related Accession (Same CDS sequence)	XM_006723404.1 , NM_025194.2 , NM_025194.3
Accession Version	XM_006723404.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	inositol-trisphosphate 3-kinase C isoform X1
Comment

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006723467.1

Translation

MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

Target ORF information:

RefSeq Version	XM_006723404.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723404.1

ORF Insert Sequence:

ATGAGGCGCT GCCCGTGCCG TGGGAGCCTG AACGAGGCGG AGGCCGGGGC GCTGCCCGCG 
GCGGCCCGCA TGGGACTGGA GGCGCCGCGA GGAGGGCGGC GGCGGCAGCC GGGACAGCAG 
CGACCTGGGC CCGGCGCAGG GGCCCCGGCG GGGCGGCCGG AGGGGGGCGG GCCCTGGGCC 
CGGACAGAGG GGTCCAGCCT CCACAGCGAG CCTGAGAGGG CCGGCCTCGG GCCTGCGCCG 
GGGACAGAGA GTCCGCAGGC AGAATTCTGG ACAGACGGAC AGACTGAGCC CGCGGCAGCT 
GGCCTTGGAG TAGAGACCGA GAGGCCCAAG CAAAAGACGG AGCCAGACAG GTCCAGCCTC 
CGGACGCATC TAGAATGGAG CTGGTCAGAG CTGGAGACGA CTTGTCTTTG GACGGAGACC 
GGGACAGATG GCCTTTGGAC TGATCCGCAC AGGTCCGACC TCCAGTTTCA GCCCGAGGAG 
GCCAGCCCCT GGACACAGCC AGGGGTTCAT GGGCCCTGGA CAGAGCTGGA AACGCATGGG 
TCACAGACTC AGCCAGAGAG GGTCAAGTCC TGGGCTGATA ACCTCTGGAC CCACCAGAAC 
AGTTCCAGCC TCCAGACTCA CCCAGAAGGA GCCTGTCCCT CAAAAGAGCC AAGTGCTGAT 
GGCTCCTGGA AAGAATTGTA TACTGATGGC TCCAGGACAC AACAGGATAT TGAAGGTCCC 
TGGACAGAGC CATATACTGA TGGCTCCCAG AAAAAACAGG ATACTGAAGC AGCCAGGAAA 
CAGCCTGGCA CTGGTGGTTT CCAAATACAA CAGGATACTG ATGGCTCCTG GACACAACCT 
AGCACTGACG GTTCCCAGAC AGCACCTGGG ACAGACTGCC TCTTGGGAGA GCCTGAGGAT 
GGCCCATTAG AGGAACCAGA GCCTGGAGAA TTGCTGACTC ACCTGTACTC TCACCTGAAG 
TGTAGCCCCC TGTGCCCTGT GCCCCGCCTC ATCATTACCC CTGAGACCCC TGAGCCTGAG 
GCCCAGCCAG TGGGACCCCC CTCCCGGGTT GAGGGGGGCA GCGGCGGCTT CTCCTCTGCC 
TCTTCTTTCG ACGAGTCTGA GGATGACGTG GTGGCCGGGG GCGGAGGTGC CAGCGATCCC 
GAGGACAGGT CTGGGAGCAA ACCCTGGAAG AAGCTGAAGA CAGTTCTGAA GTATTCACCC 
TTTGTGGTCT CCTTCCGAAA ACACTACCCT TGGGTCCAGC TTTCTGGACA TGCTGGGAAC 
TTCCAGGCAG GAGAGGATGG TCGGATTCTG AAACGTTTCT GTCAGTGTGA GCAGCGCAGC 
CTGGAGCAGC TGATGAAAGA CCCGCTGCGA CCTTTCGTGC CTGCCTACTA TGGCATGGTG 
CTGCAGGATG GCCAGACCTT CAACCAGATG GAAGACCTCC TGGCTGACTT TGAGGGCCCC 
TCCATTATGG ACTGCAAGAT GGGCAGCAGG ACCTATCTGG AAGAGGAGCT AGTGAAGGCA 
CGGGAACGTC CCCGTCCCCG GAAGGACATG TATGAGAAGA TGGTGGCTGT GGACCCTGGG 
GCCCCTACCC CTGAGGAGCA TGCCCAGGGT GCAGTCACCA AGCCCCGCTA CATGCAGTGG 
AGGGAAACCA TGAGCTCCAC CTCTACCCTG GGCTTCCGGA TCGAGGGCAT CAAGAAGGCA 
GATGGGACCT GTAACACCAA CTTCAAGAAG ACGCAGGCAC TGGAGCAGGT GACAAAAGTG 
CTGGAGGACT TCGTGGATGG AGACCACGTC ATCCTGCAAA AGTACGTGGC ATGCCTAGAA 
GAACTTCGTG AAGCTCTGGA GATCTCCCCC TTCTTCAAGA CCCACGAGGT GGTAGGCAGC 
TCCCTCCTCT TCGTGCACGA CCACACCGGC CTGGCCAAGG TCTGGATGAT AGACTTCGGC 
AAGACGGTGG CCTTGCCCGA CCACCAGACG CTCAGCCACA GGCTGCCCTG GGCTGAGGGC 
AACCGTGAGG ACGGCTACCT CTGGGGCCTG GACAACATGA TCTGCCTCCT GCAGGGGCTG 
GCACAGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKC ( XM_017027324.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882813.1 Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88733
Clone ID Related Accession (Same CDS sequence)	XM_017027324.1 , XM_017027324.2
Accession Version	XM_017027324.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 36% of CDS bases ##RefSeq-Attributes-END##

ATGGCTCCCA GAAAAAACAG GATACTGAAG CAGCCAGGAA ACAGCCTGGC ACTGGTGGTT 
TCCAAATACA ACAGGATACT GATGGCTCCT GGACACAACC TAGCACTGAC GTGTAGCCCC 
CTGTGCCCTG TGCCCCGCCT CATCATTACC CCTGAGACCC CTGAGCCTGA GGCCCAGCCA 
GTGGGACCCC CCTCCCGGGT TGAGGGGGGC AGCGGCGGCT TCTCCTCTGC CTCTTCTTTC 
GACGAGTCTG AGGATGACGT GGTGGCCGGG GGCGGAGGTG CCAGCGATCC CGAGGACAGG 
TCTGGGAGCA AACCCTGGAA GAAGCTGAAG ACAGTTCTGA AGTATTCACC CTTTGTGGTC 
TCCTTCCGAA AACACTACCC TTGGGTCCAG CTTTCTGGAC ATGCTGGCAG CTGCGGAGAG 
GTTCTCTTCC TGATCCAGTT CCTGATCCTC TCATTTATTC TACCACCTTT AGGGAACTTC 
CAGGCAGGAG AGGATGGTCG GATTCTGAAA CGTTTCTGTC AGTGTGAGCA GCGCAGCCTG 
GAGCAGCTGA TGAAAGACCC GCTGCGACCT TTCGTGCCTG CCTACTATGG CATGGTGCTG 
CAGGATGGCC AGACCTTCAA CCAGATGGAA GACCTCCTGG CTGACTTTGA GGGCCCCTCC 
ATTATGGACT GCAAGATGGG CAGCAGGACC TATCTGGAAG AGGAGCTAGT GAAGGCACGG 
GAACGTCCCC GTCCCCGGAA GGACATGTAT GAGAAGATGG TGGCTGTGGA CCCTGGGGCC 
CCTACCCCTG AGGAGCATGC CCAGGGTGCA GTCACCAAGC CCCGCTACAT GCAGTGGAGG 
GAAACCATGA GCTCCACCTC TACCCTGGGC TTCCGGATCG AGGGCATCAA GAAGGCAGAT 
GGGACCTGTA ACACCAACTT CAAGAAGACG CAGGCACTGG AGCAGGTGAC AAAAGTGCTG 
GAGGACTTCG TGGATGGAGA CCACGTCATC CTGCAAAAGT ACGTGGCATG CCTAGAAGAA 
CTTCGTGAAG CTCTGGAGAT CTCCCCCTTC TTCAAGACCC ACGAGGTGGT AGGCAGCTCC 
CTCCTCTTCG TGCACGACCA CACCGGCCTG GCCAAGGTCT GGATGATAGA CTTCGGCAAG 
ACGGTGGCCT TGCCCGACCA CCAGACGCTC AGCCACAGGC TGCCCTGGGC TGAGGGCAAC 
CGTGAGGACG GCTACCTCTG GGGCCTGGAC AACATGATCT GCCTCCTGCA GGGGCTGGCA 
CAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882813.1
CDS	1..1269
Translation	MAPRKNRILKQPGNSLALVVSKYNRILMAPGHNLALTCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGSCGEVLFLIQFLILSFILPPLGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

Target ORF information:

RefSeq Version	XM_017027324.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027324.1

ORF Insert Sequence:

ATGGCTCCCA GAAAAAACAG GATACTGAAG CAGCCAGGAA ACAGCCTGGC ACTGGTGGTT 
TCCAAATACA ACAGGATACT GATGGCTCCT GGACACAACC TAGCACTGAC GTGTAGCCCC 
CTGTGCCCTG TGCCCCGCCT CATCATTACC CCTGAGACCC CTGAGCCTGA GGCCCAGCCA 
GTGGGACCCC CCTCCCGGGT TGAGGGGGGC AGCGGCGGCT TCTCCTCTGC CTCTTCTTTC 
GACGAGTCTG AGGATGACGT GGTGGCCGGG GGCGGAGGTG CCAGCGATCC CGAGGACAGG 
TCTGGGAGCA AACCCTGGAA GAAGCTGAAG ACAGTTCTGA AGTATTCACC CTTTGTGGTC 
TCCTTCCGAA AACACTACCC TTGGGTCCAG CTTTCTGGAC ATGCTGGCAG CTGCGGAGAG 
GTTCTCTTCC TGATCCAGTT CCTGATCCTC TCATTTATTC TACCACCTTT AGGGAACTTC 
CAGGCAGGAG AGGATGGTCG GATTCTGAAA CGTTTCTGTC AGTGTGAGCA GCGCAGCCTG 
GAGCAGCTGA TGAAAGACCC GCTGCGACCT TTCGTGCCTG CCTACTATGG CATGGTGCTG 
CAGGATGGCC AGACCTTCAA CCAGATGGAA GACCTCCTGG CTGACTTTGA GGGCCCCTCC 
ATTATGGACT GCAAGATGGG CAGCAGGACC TATCTGGAAG AGGAGCTAGT GAAGGCACGG 
GAACGTCCCC GTCCCCGGAA GGACATGTAT GAGAAGATGG TGGCTGTGGA CCCTGGGGCC 
CCTACCCCTG AGGAGCATGC CCAGGGTGCA GTCACCAAGC CCCGCTACAT GCAGTGGAGG 
GAAACCATGA GCTCCACCTC TACCCTGGGC TTCCGGATCG AGGGCATCAA GAAGGCAGAT 
GGGACCTGTA ACACCAACTT CAAGAAGACG CAGGCACTGG AGCAGGTGAC AAAAGTGCTG 
GAGGACTTCG TGGATGGAGA CCACGTCATC CTGCAAAAGT ACGTGGCATG CCTAGAAGAA 
CTTCGTGAAG CTCTGGAGAT CTCCCCCTTC TTCAAGACCC ACGAGGTGGT AGGCAGCTCC 
CTCCTCTTCG TGCACGACCA CACCGGCCTG GCCAAGGTCT GGATGATAGA CTTCGGCAAG 
ACGGTGGCCT TGCCCGACCA CCAGACGCTC AGCCACAGGC TGCCCTGGGC TGAGGGCAAC 
CGTGAGGACG GCTACCTCTG GGGCCTGGAC AACATGATCT GCCTCCTGCA GGGGCTGGCA 
CAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKC ( XM_017027324.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882813.1 Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88733
Clone ID Related Accession (Same CDS sequence)	XM_017027324.1 , XM_017027324.2
Accession Version	XM_017027324.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017027324.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 36% of CDS bases ##RefSeq-Attributes-END##

ATGGCTCCCA GAAAAAACAG GATACTGAAG CAGCCAGGAA ACAGCCTGGC ACTGGTGGTT 
TCCAAATACA ACAGGATACT GATGGCTCCT GGACACAACC TAGCACTGAC GTGTAGCCCC 
CTGTGCCCTG TGCCCCGCCT CATCATTACC CCTGAGACCC CTGAGCCTGA GGCCCAGCCA 
GTGGGACCCC CCTCCCGGGT TGAGGGGGGC AGCGGCGGCT TCTCCTCTGC CTCTTCTTTC 
GACGAGTCTG AGGATGACGT GGTGGCCGGG GGCGGAGGTG CCAGCGATCC CGAGGACAGG 
TCTGGGAGCA AACCCTGGAA GAAGCTGAAG ACAGTTCTGA AGTATTCACC CTTTGTGGTC 
TCCTTCCGAA AACACTACCC TTGGGTCCAG CTTTCTGGAC ATGCTGGCAG CTGCGGAGAG 
GTTCTCTTCC TGATCCAGTT CCTGATCCTC TCATTTATTC TACCACCTTT AGGGAACTTC 
CAGGCAGGAG AGGATGGTCG GATTCTGAAA CGTTTCTGTC AGTGTGAGCA GCGCAGCCTG 
GAGCAGCTGA TGAAAGACCC GCTGCGACCT TTCGTGCCTG CCTACTATGG CATGGTGCTG 
CAGGATGGCC AGACCTTCAA CCAGATGGAA GACCTCCTGG CTGACTTTGA GGGCCCCTCC 
ATTATGGACT GCAAGATGGG CAGCAGGACC TATCTGGAAG AGGAGCTAGT GAAGGCACGG 
GAACGTCCCC GTCCCCGGAA GGACATGTAT GAGAAGATGG TGGCTGTGGA CCCTGGGGCC 
CCTACCCCTG AGGAGCATGC CCAGGGTGCA GTCACCAAGC CCCGCTACAT GCAGTGGAGG 
GAAACCATGA GCTCCACCTC TACCCTGGGC TTCCGGATCG AGGGCATCAA GAAGGCAGAT 
GGGACCTGTA ACACCAACTT CAAGAAGACG CAGGCACTGG AGCAGGTGAC AAAAGTGCTG 
GAGGACTTCG TGGATGGAGA CCACGTCATC CTGCAAAAGT ACGTGGCATG CCTAGAAGAA 
CTTCGTGAAG CTCTGGAGAT CTCCCCCTTC TTCAAGACCC ACGAGGTGGT AGGCAGCTCC 
CTCCTCTTCG TGCACGACCA CACCGGCCTG GCCAAGGTCT GGATGATAGA CTTCGGCAAG 
ACGGTGGCCT TGCCCGACCA CCAGACGCTC AGCCACAGGC TGCCCTGGGC TGAGGGCAAC 
CGTGAGGACG GCTACCTCTG GGGCCTGGAC AACATGATCT GCCTCCTGCA GGGGCTGGCA 
CAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882813.1
CDS	1..1269
Translation	MAPRKNRILKQPGNSLALVVSKYNRILMAPGHNLALTCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGSCGEVLFLIQFLILSFILPPLGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQS

Target ORF information:

RefSeq Version	XM_017027324.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase C (ITPKC), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027324.2

ORF Insert Sequence:

ATGGCTCCCA GAAAAAACAG GATACTGAAG CAGCCAGGAA ACAGCCTGGC ACTGGTGGTT 
TCCAAATACA ACAGGATACT GATGGCTCCT GGACACAACC TAGCACTGAC GTGTAGCCCC 
CTGTGCCCTG TGCCCCGCCT CATCATTACC CCTGAGACCC CTGAGCCTGA GGCCCAGCCA 
GTGGGACCCC CCTCCCGGGT TGAGGGGGGC AGCGGCGGCT TCTCCTCTGC CTCTTCTTTC 
GACGAGTCTG AGGATGACGT GGTGGCCGGG GGCGGAGGTG CCAGCGATCC CGAGGACAGG 
TCTGGGAGCA AACCCTGGAA GAAGCTGAAG ACAGTTCTGA AGTATTCACC CTTTGTGGTC 
TCCTTCCGAA AACACTACCC TTGGGTCCAG CTTTCTGGAC ATGCTGGCAG CTGCGGAGAG 
GTTCTCTTCC TGATCCAGTT CCTGATCCTC TCATTTATTC TACCACCTTT AGGGAACTTC 
CAGGCAGGAG AGGATGGTCG GATTCTGAAA CGTTTCTGTC AGTGTGAGCA GCGCAGCCTG 
GAGCAGCTGA TGAAAGACCC GCTGCGACCT TTCGTGCCTG CCTACTATGG CATGGTGCTG 
CAGGATGGCC AGACCTTCAA CCAGATGGAA GACCTCCTGG CTGACTTTGA GGGCCCCTCC 
ATTATGGACT GCAAGATGGG CAGCAGGACC TATCTGGAAG AGGAGCTAGT GAAGGCACGG 
GAACGTCCCC GTCCCCGGAA GGACATGTAT GAGAAGATGG TGGCTGTGGA CCCTGGGGCC 
CCTACCCCTG AGGAGCATGC CCAGGGTGCA GTCACCAAGC CCCGCTACAT GCAGTGGAGG 
GAAACCATGA GCTCCACCTC TACCCTGGGC TTCCGGATCG AGGGCATCAA GAAGGCAGAT 
GGGACCTGTA ACACCAACTT CAAGAAGACG CAGGCACTGG AGCAGGTGAC AAAAGTGCTG 
GAGGACTTCG TGGATGGAGA CCACGTCATC CTGCAAAAGT ACGTGGCATG CCTAGAAGAA 
CTTCGTGAAG CTCTGGAGAT CTCCCCCTTC TTCAAGACCC ACGAGGTGGT AGGCAGCTCC 
CTCCTCTTCG TGCACGACCA CACCGGCCTG GCCAAGGTCT GGATGATAGA CTTCGGCAAG 
ACGGTGGCCT TGCCCGACCA CCAGACGCTC AGCCACAGGC TGCCCTGGGC TGAGGGCAAC 
CGTGAGGACG GCTACCTCTG GGGCCTGGAC AACATGATCT GCCTCCTGCA GGGGCTGGCA 
CAGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ITPKC and SLC11A1 Gene Polymorphisms and Gene-Gene Interactions in Korean Patients with Kawasaki Disease.
Yonsei medical journal59(1)119-127(2018 Jan)
Kim KY,Bae YS,Ji W,Shin D,Kim HS,Kim DS

Potential association between ITPKC genetic variations and Hirschsprung disease.
Molecular biology reports44(3)307-313(2017 Jul)
Kim JH,Jung SM,Shin JG,Cheong HS,Seo JM,Kim DY,Oh JT,Kim HY,Jung K,Shin HD

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The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.
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ITPKC cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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