EFHC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EFHC2
Entrez Gene ID	80258
Full Name	EF-hand domain containing 2
Synonyms	MRX74,dJ1158H2.1
General protein information	Preferred Names EF-hand domain containing 2 Names EF-hand domain-containing family member C2 EF-hand domain (C-terminal) containing 2 mental retardation, X-linked 74
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.3
Summary	This gene encodes a protein which contains three DM10 domains and three calcium-binding EF-hand motifs. A related protein is encoded by a gene on chromosome 6. It has been suggested that both proteins are involved in the development of epilepsy (PMID: 15258581, 16112844) and that this gene may be associated with fear recognition in individuals with Turner syndrome. [provided by RefSeq, Aug 2011].
Disorder MIM:	300817

mRNA and Protein(s)

mRNA	Protein	Name
XM_024452453.1	XP_024308221.1	EF-hand domain-containing family member C2 isoform X1
XM_006724562.2	XP_006724625.1	EF-hand domain-containing family member C2 isoform X2
NM_025184.3	NP_079460.2	EF-hand domain-containing family member C2
NM_025184.4	NP_079460.2	EF-hand domain-containing family member C2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Efhc2	NP_083192.2
Danio rerio (zebrafish)	efhc2	NP_001032472.1
Bos taurus (cattle)	EFHC2	XP_002700247.1
Gallus gallus (chicken)	EFHC2	NP_001032918.1
Drosophila melanogaster (fruit fly)	Efhc1.1	NP_573075.1
Homo sapiens (human)	EFHC2	NP_079460.2
	LOC709087	XP_001097580.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003339	XP_558349.4
Pan troglodytes (chimpanzee)	EFHC2	XP_003317486.1
Rattus norvegicus (Norway rat)	Efhc2	NP_001100422.1
Xenopus tropicalis (tropical clawed frog)	efhc2	NP_001136133.1
Canis lupus familiaris (dog)	EFHC2	XP_005641323.1
Drosophila melanogaster (fruit fly)	Efhc1.2	NP_611459.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits.
Jia B, Huang L, Chen Y, Liu S, Chen C, Xiong K, Song L, Zhou Y, Yang X, Zhong M
Journal of genetics96(6)1015-1020(2017 Dec)

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

No relation between EFHC2 gene polymorphism and Idiopathic generalized epilepsy.
Berrin T, Hikmet Y, G?l?en V, Ferda B, Erdal B, Ece O
African health sciences15(4)1204-10(2015 Dec)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.
Startin CM, Fiorentini C, de Haan M, Skuse DH
PloS one10(6)e0131604(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In our series of 96 IGE patients and 96 healthy controls, there was no relation between S430Y polymorphism in EFHC2 gene and IGE presence.
Title: No relation between EFHC2 gene polymorphism and Idiopathic generalized epilepsy.

EFHC2 variation at SNP rs7055196 is associated with social cognitive abilities in males
Title: Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.

This study found that the association between a variant in EFHC2 with the processing of fear and social threat and harm reduction.
Title: Preliminary evidence of association between EFHC2, a gene implicated in fear recognition, and harm avoidance.

Observational study of gene-disease association. (HuGE Navigator)
Title: EFHC2 SNP rs7055196 is not associated with fear recognition in 45,X Turner syndrome.

EFHC2 shows genealogy and extended LD consistent with directional selection. This novel QTL may influence social cognition in the general population and in autism.
Title: Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome.

The following EFHC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EFHC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19450	NM_025184.4 Latest version!	Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu54037	XM_006724562.2 Latest version!	Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu106284	XM_024452453.1 Latest version!	Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu19450	NM_025184.3	Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EFHC2 ( NM_025184.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079460.2 Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.

Price & Availability↑

CloneID	OHu19450
Clone ID Related Accession (Same CDS sequence)	NM_025184.3 , NM_025184.4
Accession Version	NM_025184.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	EF-hand domain-containing family member C2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC331145.1, BC031039.1, AK026254.1 and AL359744.17. This sequence is a reference standard in the RefSeqGene project. On Jun 9, 2007 this sequence version replaced NM_025184.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.185818.1, SRR1803615.108399.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCTGC CTCTGCTGCC GGGCAACAGC TTCAACCGCA ACGTGGGAAA GGAGAAGTTT 
CACAAATCCC AACATTGGGG CTTTTGCAAC AATGTTATGA TGTTGGTGAG TGATGAAAAG 
CCTGGAATAG GTGGAGAACC ACTTCTGGGG CAAAAGATAA AGCCTAAATG TAGCATATAT 
CCTAAAGGAG ATGGAAGTGA TGTACCATCA TGGGTAGCCT TTGATAAACA GGTATTATCT 
TTTGATGCCT ATTTGGAAGA GGAAGTACTT GATAAAAGCC AAACCAACTA CAGAATAAGA 
TACTATAAAA TCTACTTCTA CCCTGAAGAT GACACAATTC AAGTAAATGA ACCAGAGGTG 
AAAAATAGTG GATTACTTCA AGGGACTTCT ATCCGGCGTC ATCGGATTAC TCTTCCGCCT 
CCTGATGAGG ATCAGTTTTA TACTGTGTAT CATTTTAATG TCGGCACAGA GGTTGTCTTC 
TATGGCCGGA CATTCAAGAT TTATGACTGT GATGCATTCA CAAGAAACTT TTTGAGGAAA 
ATAGGGGTCA AAGTGAATCC CCCAGTGCAA TGTCCAGAAG ATCCTTACAT GAAGATTCGG 
AGAGAGGTTG TAGAACACGT AGAGCCCTTA CGTCCCTACG AATCCCTCGA CACCCTGAAA 
CAGTTCCTCC AGTATCATGG CAAGATTTTG TGTTTCTTCT GCCTGTGGGA TGACTCAGTC 
TCAATGTTTG GAGACCGTAG AGAACTCATC CTGCATTACT TCTTGTGTGA TGATACTATT 
GAAATCAAAG AATTGCTTCC ACACAGCTCA GGCCGAGATG CTCTAAAAAT GTTCCTCCGG 
AGGAGTAAGC TACCCAAGAA TTGCCCACCT AGAGTCTATC AACCAGGCCA GATAACAGAT 
CGAGCAGTTC TCAATTCATA TGGTGACTTT ATAAAGAACC AAGCGGATGG CTACCTGTTC 
GATAGATATA AGCTAGGAAA AGTAGACCAA GAGTTTTACA AAGATAGTGA CCTGTCCCTA 
GGAGTCACCA TCAATGTGTG GGGAAGAAAA GTGCTCCTTT ATGACTGTGA TGAATTTACG 
AAGTCTTATT ATAAGTCTAA ATATGGAATT GAGAACTTTA CCTCAGTTTC ATGCAAGCCT 
CCTTCTCCTC CTCCAAAAAT AGAAAGGAAA TTTCCACCTT ACAACGGTTT TGGTTCTGAA 
GAGGATTCTC TCCGTAACTG CATAGACCTC AAGCCCACAC CTCATCGGAG GAACTTCAAG 
AAGTTTATGG AAAAAGACAG CTATGGCTCC AAAAGCAATA TACTCCGTTT TTTTGCAAAA 
CTAGTCACAG ACAAATGTGT TGACTTGGAC AGGATGTTTG TTATTTCATA TTATCTCGGT 
GATGACACCA TTTCAGTGTT TGAACCTATA GAGAGGAATT CAGGAATTGC TGGTGGGATG 
TTCTTGAAAA GAAGTCGCGT TAAGAAGCCT GGACAAGAAG TCTTTAAAAG TGAACTATCT 
GAATATATCA AGGCCGAGGA GCTGTACATT GGAGTCACGG TGAATGTGAA TGGTTACCTA 
TTTCGTTTGC TCAATGCTGA TGAGTATACC TTAAACTACA TGGAGCAGAA TACAGATAAG 
TATCCTTTCA GTAACCTCAA ACTTGCCCTA CAAAAGCTGA AGCAAGAAGA AGGAAAATCC 
AGAGAGCTCA AGCAGGTATT TAAAGCTGCT GACTCTAAGC ACACAAATAT GGTGGATTAT 
AATACATTCA GAGACATATT GATGTCTTTG ACTGTTGGAA ACCTTGCAGA GCAAGAATTT 
GTAACCATTG CACGTCACTA CCGTGTGCCT GAGGGCACAT GTTCAGATAT GGATTTCTTA 
ATCGCACTGG CCCACGAAAA GTTCAAGAAA AATATGTTTG AGAATTTCGA CACTTTCATT 
TATTCCTGTG TGTATGAAGA TCGAGAAAAA AAAAATGTAT TACCCACCAA AGACATTAAA 
AGGCTGTGCA AATCCTCCAG ATTACCTTTG AGTGATGATC TTCTAGAATC CTTATTGTCA 
AGGTTTGAAG ACAGTGAAAA ACAAATAGAT TATAAGTCAT TTTTCTCTGC CCTGAACTGG 
AGAAAGAATC CAGTGCCTGA ATTGCAACCA GCATCATACC TTAAAGAGAG ATGTGAAGAT 
GTTTGGCTTG GTATGCCATC ACCTATTCCT GCGAAATACA TTGACTACTG GACCTTTTTG 
AAGGACGCGT TTGGCTTAGA GGAGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079460.2
CDS	91..2340
Translation	MALPLLPGNSFNRNVGKEKFHKSQHWGFCNNVMMLVSDEKPGIGGEPLLGQKIKPKCSIYPKGDGSDVPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIRYYKIYFYPEDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVFYGRTFKIYDCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPYESLDTLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDTFIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSALNWRKNPVPELQPASYLKERCEDVWLGMPSPIPAKYIDYWTFLKDAFGLEEE

Target ORF information:

RefSeq Version	NM_025184.3
Organism	Homo sapiens(human)
Definition	Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025184.3

ORF Insert Sequence:

ATGGCCCTGC CTCTGCTGCC GGGCAACAGC TTCAACCGCA ACGTGGGAAA GGAGAAGTTT 
CACAAATCCC AACATTGGGG CTTTTGCAAC AATGTTATGA TGTTGGTGAG TGATGAAAAG 
CCTGGAATAG GTGGAGAACC ACTTCTGGGG CAAAAGATAA AGCCTAAATG TAGCATATAT 
CCTAAAGGAG ATGGAAGTGA TGTACCATCA TGGGTAGCCT TTGATAAACA GGTATTATCT 
TTTGATGCCT ATTTGGAAGA GGAAGTACTT GATAAAAGCC AAACCAACTA CAGAATAAGA 
TACTATAAAA TCTACTTCTA CCCTGAAGAT GACACAATTC AAGTAAATGA ACCAGAGGTG 
AAAAATAGTG GATTACTTCA AGGGACTTCT ATCCGGCGTC ATCGGATTAC TCTTCCGCCT 
CCTGATGAGG ATCAGTTTTA TACTGTGTAT CATTTTAATG TCGGCACAGA GGTTGTCTTC 
TATGGCCGGA CATTCAAGAT TTATGACTGT GATGCATTCA CAAGAAACTT TTTGAGGAAA 
ATAGGGGTCA AAGTGAATCC CCCAGTGCAA TGTCCAGAAG ATCCTTACAT GAAGATTCGG 
AGAGAGGTTG TAGAACACGT AGAGCCCTTA CGTCCCTACG AATCCCTCGA CACCCTGAAA 
CAGTTCCTCC AGTATCATGG CAAGATTTTG TGTTTCTTCT GCCTGTGGGA TGACTCAGTC 
TCAATGTTTG GAGACCGTAG AGAACTCATC CTGCATTACT TCTTGTGTGA TGATACTATT 
GAAATCAAAG AATTGCTTCC ACACAGCTCA GGCCGAGATG CTCTAAAAAT GTTCCTCCGG 
AGGAGTAAGC TACCCAAGAA TTGCCCACCT AGAGTCTATC AACCAGGCCA GATAACAGAT 
CGAGCAGTTC TCAATTCATA TGGTGACTTT ATAAAGAACC AAGCGGATGG CTACCTGTTC 
GATAGATATA AGCTAGGAAA AGTAGACCAA GAGTTTTACA AAGATAGTGA CCTGTCCCTA 
GGAGTCACCA TCAATGTGTG GGGAAGAAAA GTGCTCCTTT ATGACTGTGA TGAATTTACG 
AAGTCTTATT ATAAGTCTAA ATATGGAATT GAGAACTTTA CCTCAGTTTC ATGCAAGCCT 
CCTTCTCCTC CTCCAAAAAT AGAAAGGAAA TTTCCACCTT ACAACGGTTT TGGTTCTGAA 
GAGGATTCTC TCCGTAACTG CATAGACCTC AAGCCCACAC CTCATCGGAG GAACTTCAAG 
AAGTTTATGG AAAAAGACAG CTATGGCTCC AAAAGCAATA TACTCCGTTT TTTTGCAAAA 
CTAGTCACAG ACAAATGTGT TGACTTGGAC AGGATGTTTG TTATTTCATA TTATCTCGGT 
GATGACACCA TTTCAGTGTT TGAACCTATA GAGAGGAATT CAGGAATTGC TGGTGGGATG 
TTCTTGAAAA GAAGTCGCGT TAAGAAGCCT GGACAAGAAG TCTTTAAAAG TGAACTATCT 
GAATATATCA AGGCCGAGGA GCTGTACATT GGAGTCACGG TGAATGTGAA TGGTTACCTA 
TTTCGTTTGC TCAATGCTGA TGAGTATACC TTAAACTACA TGGAGCAGAA TACAGATAAG 
TATCCTTTCA GTAACCTCAA ACTTGCCCTA CAAAAGCTGA AGCAAGAAGA AGGAAAATCC 
AGAGAGCTCA AGCAGGTATT TAAAGCTGCT GACTCTAAGC ACACAAATAT GGTGGATTAT 
AATACATTCA GAGACATATT GATGTCTTTG ACTGTTGGAA ACCTTGCAGA GCAAGAATTT 
GTAACCATTG CACGTCACTA CCGTGTGCCT GAGGGCACAT GTTCAGATAT GGATTTCTTA 
ATCGCACTGG CCCACGAAAA GTTCAAGAAA AATATGTTTG AGAATTTCGA CACTTTCATT 
TATTCCTGTG TGTATGAAGA TCGAGAAAAA AAAAATGTAT TACCCACCAA AGACATTAAA 
AGGCTGTGCA AATCCTCCAG ATTACCTTTG AGTGATGATC TTCTAGAATC CTTATTGTCA 
AGGTTTGAAG ACAGTGAAAA ACAAATAGAT TATAAGTCAT TTTTCTCTGC CCTGAACTGG 
AGAAAGAATC CAGTGCCTGA ATTGCAACCA GCATCATACC TTAAAGAGAG ATGTGAAGAT 
GTTTGGCTTG GTATGCCATC ACCTATTCCT GCGAAATACA TTGACTACTG GACCTTTTTG 
AAGGACGCGT TTGGCTTAGA GGAGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EFHC2 ( NM_025184.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_079460.2 Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.

Price & Availability↑

CloneID	OHu19450
Clone ID Related Accession (Same CDS sequence)	NM_025184.3 , NM_025184.4
Accession Version	NM_025184.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	EF-hand domain-containing family member C2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC018719.4, AL133344.28 and AL359744.17. On Nov 23, 2018 this sequence version replaced NM_025184.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031039.1, SRR1803617.185818.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000420999.2/ ENSP00000404232.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCCTGC CTCTGCTGCC GGGCAACAGC TTCAACCGCA ACGTGGGAAA GGAGAAGTTT 
CACAAATCCC AACATTGGGG CTTTTGCAAC AATGTTATGA TGTTGGTGAG TGATGAAAAG 
CCTGGAATAG GTGGAGAACC ACTTCTGGGG CAAAAGATAA AGCCTAAATG TAGCATATAT 
CCTAAAGGAG ATGGAAGTGA TGTACCATCA TGGGTAGCCT TTGATAAACA GGTATTATCT 
TTTGATGCCT ATTTGGAAGA GGAAGTACTT GATAAAAGCC AAACCAACTA CAGAATAAGA 
TACTATAAAA TCTACTTCTA CCCTGAAGAT GACACAATTC AAGTAAATGA ACCAGAGGTG 
AAAAATAGTG GATTACTTCA AGGGACTTCT ATCCGGCGTC ATCGGATTAC TCTTCCGCCT 
CCTGATGAGG ATCAGTTTTA TACTGTGTAT CATTTTAATG TCGGCACAGA GGTTGTCTTC 
TATGGCCGGA CATTCAAGAT TTATGACTGT GATGCATTCA CAAGAAACTT TTTGAGGAAA 
ATAGGGGTCA AAGTGAATCC CCCAGTGCAA TGTCCAGAAG ATCCTTACAT GAAGATTCGG 
AGAGAGGTTG TAGAACACGT AGAGCCCTTA CGTCCCTACG AATCCCTCGA CACCCTGAAA 
CAGTTCCTCC AGTATCATGG CAAGATTTTG TGTTTCTTCT GCCTGTGGGA TGACTCAGTC 
TCAATGTTTG GAGACCGTAG AGAACTCATC CTGCATTACT TCTTGTGTGA TGATACTATT 
GAAATCAAAG AATTGCTTCC ACACAGCTCA GGCCGAGATG CTCTAAAAAT GTTCCTCCGG 
AGGAGTAAGC TACCCAAGAA TTGCCCACCT AGAGTCTATC AACCAGGCCA GATAACAGAT 
CGAGCAGTTC TCAATTCATA TGGTGACTTT ATAAAGAACC AAGCGGATGG CTACCTGTTC 
GATAGATATA AGCTAGGAAA AGTAGACCAA GAGTTTTACA AAGATAGTGA CCTGTCCCTA 
GGAGTCACCA TCAATGTGTG GGGAAGAAAA GTGCTCCTTT ATGACTGTGA TGAATTTACG 
AAGTCTTATT ATAAGTCTAA ATATGGAATT GAGAACTTTA CCTCAGTTTC ATGCAAGCCT 
CCTTCTCCTC CTCCAAAAAT AGAAAGGAAA TTTCCACCTT ACAACGGTTT TGGTTCTGAA 
GAGGATTCTC TCCGTAACTG CATAGACCTC AAGCCCACAC CTCATCGGAG GAACTTCAAG 
AAGTTTATGG AAAAAGACAG CTATGGCTCC AAAAGCAATA TACTCCGTTT TTTTGCAAAA 
CTAGTCACAG ACAAATGTGT TGACTTGGAC AGGATGTTTG TTATTTCATA TTATCTCGGT 
GATGACACCA TTTCAGTGTT TGAACCTATA GAGAGGAATT CAGGAATTGC TGGTGGGATG 
TTCTTGAAAA GAAGTCGCGT TAAGAAGCCT GGACAAGAAG TCTTTAAAAG TGAACTATCT 
GAATATATCA AGGCCGAGGA GCTGTACATT GGAGTCACGG TGAATGTGAA TGGTTACCTA 
TTTCGTTTGC TCAATGCTGA TGAGTATACC TTAAACTACA TGGAGCAGAA TACAGATAAG 
TATCCTTTCA GTAACCTCAA ACTTGCCCTA CAAAAGCTGA AGCAAGAAGA AGGAAAATCC 
AGAGAGCTCA AGCAGGTATT TAAAGCTGCT GACTCTAAGC ACACAAATAT GGTGGATTAT 
AATACATTCA GAGACATATT GATGTCTTTG ACTGTTGGAA ACCTTGCAGA GCAAGAATTT 
GTAACCATTG CACGTCACTA CCGTGTGCCT GAGGGCACAT GTTCAGATAT GGATTTCTTA 
ATCGCACTGG CCCACGAAAA GTTCAAGAAA AATATGTTTG AGAATTTCGA CACTTTCATT 
TATTCCTGTG TGTATGAAGA TCGAGAAAAA AAAAATGTAT TACCCACCAA AGACATTAAA 
AGGCTGTGCA AATCCTCCAG ATTACCTTTG AGTGATGATC TTCTAGAATC CTTATTGTCA 
AGGTTTGAAG ACAGTGAAAA ACAAATAGAT TATAAGTCAT TTTTCTCTGC CCTGAACTGG 
AGAAAGAATC CAGTGCCTGA ATTGCAACCA GCATCATACC TTAAAGAGAG ATGTGAAGAT 
GTTTGGCTTG GTATGCCATC ACCTATTCCT GCGAAATACA TTGACTACTG GACCTTTTTG 
AAGGACGCGT TTGGCTTAGA GGAGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079460.2
CDS	85..2334
Translation	MALPLLPGNSFNRNVGKEKFHKSQHWGFCNNVMMLVSDEKPGIGGEPLLGQKIKPKCSIYPKGDGSDVPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIRYYKIYFYPEDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVFYGRTFKIYDCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPYESLDTLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDTFIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSALNWRKNPVPELQPASYLKERCEDVWLGMPSPIPAKYIDYWTFLKDAFGLEEE

Target ORF information:

RefSeq Version	NM_025184.4
Organism	Homo sapiens(human)
Definition	Homo sapiens EF-hand domain containing 2 (EFHC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025184.4

ORF Insert Sequence:

ATGGCCCTGC CTCTGCTGCC GGGCAACAGC TTCAACCGCA ACGTGGGAAA GGAGAAGTTT 
CACAAATCCC AACATTGGGG CTTTTGCAAC AATGTTATGA TGTTGGTGAG TGATGAAAAG 
CCTGGAATAG GTGGAGAACC ACTTCTGGGG CAAAAGATAA AGCCTAAATG TAGCATATAT 
CCTAAAGGAG ATGGAAGTGA TGTACCATCA TGGGTAGCCT TTGATAAACA GGTATTATCT 
TTTGATGCCT ATTTGGAAGA GGAAGTACTT GATAAAAGCC AAACCAACTA CAGAATAAGA 
TACTATAAAA TCTACTTCTA CCCTGAAGAT GACACAATTC AAGTAAATGA ACCAGAGGTG 
AAAAATAGTG GATTACTTCA AGGGACTTCT ATCCGGCGTC ATCGGATTAC TCTTCCGCCT 
CCTGATGAGG ATCAGTTTTA TACTGTGTAT CATTTTAATG TCGGCACAGA GGTTGTCTTC 
TATGGCCGGA CATTCAAGAT TTATGACTGT GATGCATTCA CAAGAAACTT TTTGAGGAAA 
ATAGGGGTCA AAGTGAATCC CCCAGTGCAA TGTCCAGAAG ATCCTTACAT GAAGATTCGG 
AGAGAGGTTG TAGAACACGT AGAGCCCTTA CGTCCCTACG AATCCCTCGA CACCCTGAAA 
CAGTTCCTCC AGTATCATGG CAAGATTTTG TGTTTCTTCT GCCTGTGGGA TGACTCAGTC 
TCAATGTTTG GAGACCGTAG AGAACTCATC CTGCATTACT TCTTGTGTGA TGATACTATT 
GAAATCAAAG AATTGCTTCC ACACAGCTCA GGCCGAGATG CTCTAAAAAT GTTCCTCCGG 
AGGAGTAAGC TACCCAAGAA TTGCCCACCT AGAGTCTATC AACCAGGCCA GATAACAGAT 
CGAGCAGTTC TCAATTCATA TGGTGACTTT ATAAAGAACC AAGCGGATGG CTACCTGTTC 
GATAGATATA AGCTAGGAAA AGTAGACCAA GAGTTTTACA AAGATAGTGA CCTGTCCCTA 
GGAGTCACCA TCAATGTGTG GGGAAGAAAA GTGCTCCTTT ATGACTGTGA TGAATTTACG 
AAGTCTTATT ATAAGTCTAA ATATGGAATT GAGAACTTTA CCTCAGTTTC ATGCAAGCCT 
CCTTCTCCTC CTCCAAAAAT AGAAAGGAAA TTTCCACCTT ACAACGGTTT TGGTTCTGAA 
GAGGATTCTC TCCGTAACTG CATAGACCTC AAGCCCACAC CTCATCGGAG GAACTTCAAG 
AAGTTTATGG AAAAAGACAG CTATGGCTCC AAAAGCAATA TACTCCGTTT TTTTGCAAAA 
CTAGTCACAG ACAAATGTGT TGACTTGGAC AGGATGTTTG TTATTTCATA TTATCTCGGT 
GATGACACCA TTTCAGTGTT TGAACCTATA GAGAGGAATT CAGGAATTGC TGGTGGGATG 
TTCTTGAAAA GAAGTCGCGT TAAGAAGCCT GGACAAGAAG TCTTTAAAAG TGAACTATCT 
GAATATATCA AGGCCGAGGA GCTGTACATT GGAGTCACGG TGAATGTGAA TGGTTACCTA 
TTTCGTTTGC TCAATGCTGA TGAGTATACC TTAAACTACA TGGAGCAGAA TACAGATAAG 
TATCCTTTCA GTAACCTCAA ACTTGCCCTA CAAAAGCTGA AGCAAGAAGA AGGAAAATCC 
AGAGAGCTCA AGCAGGTATT TAAAGCTGCT GACTCTAAGC ACACAAATAT GGTGGATTAT 
AATACATTCA GAGACATATT GATGTCTTTG ACTGTTGGAA ACCTTGCAGA GCAAGAATTT 
GTAACCATTG CACGTCACTA CCGTGTGCCT GAGGGCACAT GTTCAGATAT GGATTTCTTA 
ATCGCACTGG CCCACGAAAA GTTCAAGAAA AATATGTTTG AGAATTTCGA CACTTTCATT 
TATTCCTGTG TGTATGAAGA TCGAGAAAAA AAAAATGTAT TACCCACCAA AGACATTAAA 
AGGCTGTGCA AATCCTCCAG ATTACCTTTG AGTGATGATC TTCTAGAATC CTTATTGTCA 
AGGTTTGAAG ACAGTGAAAA ACAAATAGAT TATAAGTCAT TTTTCTCTGC CCTGAACTGG 
AGAAAGAATC CAGTGCCTGA ATTGCAACCA GCATCATACC TTAAAGAGAG ATGTGAAGAT 
GTTTGGCTTG GTATGCCATC ACCTATTCCT GCGAAATACA TTGACTACTG GACCTTTTTG 
AAGGACGCGT TTGGCTTAGA GGAGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EFHC2 ( XM_006724562.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006724625.1 Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X3, mRNA.

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CloneID	OHu54037
Clone ID Related Accession (Same CDS sequence)	XM_006724562.2
Accession Version	XM_006724562.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1662bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	EF-hand domain-containing family member C2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006724562.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGATTC GGAGAGAGGT TGTAGAACAC GTAGAGCCCT TACGTCCCTA CGAATCCCTC 
GACACCCTGA AACAGTTCCT CCAGTATCAT GGCAAGATTT TGTGTTTCTT CTGCCTGTGG 
GATGACTCAG TCTCAATGTT TGGAGACCGT AGAGAACTCA TCCTGCATTA CTTCTTGTGT 
GATGATACTA TTGAAATCAA AGAATTGCTT CCACACAGCT CAGGCCGAGA TGCTCTAAAA 
ATGTTCCTCC GGAGGAGTAA GCTACCCAAG AATTGCCCAC CTAGAGTCTA TCAACCAGGC 
CAGATAACAG ATCGAGCAGT TCTCAATTCA TATGGTGACT TTATAAAGAA CCAAGCGGAT 
GGCTACCTGT TCGATAGATA TAAGCTAGGA AAAGTAGACC AAGAGTTTTA CAAAGATAGT 
GACCTGTCCC TAGGAGTCAC CATCAATGTG TGGGGAAGAA AAGTGCTCCT TTATGACTGT 
GATGAATTTA CGAAGTCTTA TTATAAGTCT AAATATGGAA TTGAGAACTT TACCTCAGTT 
TCATGCAAGC CTCCTTCTCC TCCTCCAAAA ATAGAAAGGA AATTTCCACC TTACAACGGT 
TTTGGTTCTG AAGAGGATTC TCTCCGTAAC TGCATAGACC TCAAGCCCAC ACCTCATCGG 
AGGAACTTCA AGAAGTTTAT GGAAAAAGAC AGCTATGGCT CCAAAAGCAA TATACTCCGT 
TTTTTTGCAA AACTAGTCAC AGACAAATGT GTTGACTTGG ACAGGATGTT TGTTATTTCA 
TATTATCTCG GTGATGACAC CATTTCAGTG TTTGAACCTA TAGAGAGGAA TTCAGGAATT 
GCTGGTGGGA TGTTCTTGAA AAGAAGTCGC GTTAAGAAGC CTGGACAAGA AGTCTTTAAA 
AGTGAACTAT CTGAATATAT CAAGGCCGAG GAGCTGTACA TTGGAGTCAC GGTGAATGTG 
AATGGTTACC TATTTCGTTT GCTCAATGCT GATGAGTATA CCTTAAACTA CATGGAGCAG 
AATACAGATA AGTATCCTTT CAGTAACCTC AAACTTGCCC TACAAAAGCT GAAGCAAGAA 
GAAGGAAAAT CCAGAGAGCT CAAGCAGGTA TTTAAAGCTG CTGACTCTAA GCACACAAAT 
ATGGTGGATT ATAATACATT CAGAGACATA TTGATGTCTT TGACTGTTGG AAACCTTGCA 
GAGCAAGAAT TTGTAACCAT TGCACGTCAC TACCGTGTGC CTGAGGGCAC ATGTTCAGAT 
ATGGATTTCT TAATCGCACT GGCCCACGAA AAGTTCAAGA AAAATATGTT TGAGAATTTC 
GACACTTTCA TTTATTCCTG TGTGTATGAA GATCGAGAAA AAAAAAATGT ATTACCCACC 
AAAGACATTA AAAGGCTGTG CAAATCCTCC AGATTACCTT TGAGTGATGA TCTTCTAGAA 
TCCTTATTGT CAAGGTTTGA AGACAGTGAA AAACAAATAG ATTATAAGTC ATTTTTCTCT 
GCCCTGAACT GGAGAAAGAA TCCAGTGCCT GAATTGCAAC CAGCATCATA CCTTAAAGAG 
AGATGTGAAG ATGTTTGGCT TGGTATGCCA TCACCTATTC CTGCGAAATA CATTGACTAC 
TGGACCTTTT TGAAGGACGC GTTTGGCTTA GAGGAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006724625.1
CDS	392..2053
Translation	MKIRREVVEHVEPLRPYESLDTLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDTFIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSALNWRKNPVPELQPASYLKERCEDVWLGMPSPIPAKYIDYWTFLKDAFGLEEE

Target ORF information:

RefSeq Version	XM_006724562.2
Organism	Homo sapiens(human)
Definition	Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006724562.2

ORF Insert Sequence:

ATGAAGATTC GGAGAGAGGT TGTAGAACAC GTAGAGCCCT TACGTCCCTA CGAATCCCTC 
GACACCCTGA AACAGTTCCT CCAGTATCAT GGCAAGATTT TGTGTTTCTT CTGCCTGTGG 
GATGACTCAG TCTCAATGTT TGGAGACCGT AGAGAACTCA TCCTGCATTA CTTCTTGTGT 
GATGATACTA TTGAAATCAA AGAATTGCTT CCACACAGCT CAGGCCGAGA TGCTCTAAAA 
ATGTTCCTCC GGAGGAGTAA GCTACCCAAG AATTGCCCAC CTAGAGTCTA TCAACCAGGC 
CAGATAACAG ATCGAGCAGT TCTCAATTCA TATGGTGACT TTATAAAGAA CCAAGCGGAT 
GGCTACCTGT TCGATAGATA TAAGCTAGGA AAAGTAGACC AAGAGTTTTA CAAAGATAGT 
GACCTGTCCC TAGGAGTCAC CATCAATGTG TGGGGAAGAA AAGTGCTCCT TTATGACTGT 
GATGAATTTA CGAAGTCTTA TTATAAGTCT AAATATGGAA TTGAGAACTT TACCTCAGTT 
TCATGCAAGC CTCCTTCTCC TCCTCCAAAA ATAGAAAGGA AATTTCCACC TTACAACGGT 
TTTGGTTCTG AAGAGGATTC TCTCCGTAAC TGCATAGACC TCAAGCCCAC ACCTCATCGG 
AGGAACTTCA AGAAGTTTAT GGAAAAAGAC AGCTATGGCT CCAAAAGCAA TATACTCCGT 
TTTTTTGCAA AACTAGTCAC AGACAAATGT GTTGACTTGG ACAGGATGTT TGTTATTTCA 
TATTATCTCG GTGATGACAC CATTTCAGTG TTTGAACCTA TAGAGAGGAA TTCAGGAATT 
GCTGGTGGGA TGTTCTTGAA AAGAAGTCGC GTTAAGAAGC CTGGACAAGA AGTCTTTAAA 
AGTGAACTAT CTGAATATAT CAAGGCCGAG GAGCTGTACA TTGGAGTCAC GGTGAATGTG 
AATGGTTACC TATTTCGTTT GCTCAATGCT GATGAGTATA CCTTAAACTA CATGGAGCAG 
AATACAGATA AGTATCCTTT CAGTAACCTC AAACTTGCCC TACAAAAGCT GAAGCAAGAA 
GAAGGAAAAT CCAGAGAGCT CAAGCAGGTA TTTAAAGCTG CTGACTCTAA GCACACAAAT 
ATGGTGGATT ATAATACATT CAGAGACATA TTGATGTCTT TGACTGTTGG AAACCTTGCA 
GAGCAAGAAT TTGTAACCAT TGCACGTCAC TACCGTGTGC CTGAGGGCAC ATGTTCAGAT 
ATGGATTTCT TAATCGCACT GGCCCACGAA AAGTTCAAGA AAAATATGTT TGAGAATTTC 
GACACTTTCA TTTATTCCTG TGTGTATGAA GATCGAGAAA AAAAAAATGT ATTACCCACC 
AAAGACATTA AAAGGCTGTG CAAATCCTCC AGATTACCTT TGAGTGATGA TCTTCTAGAA 
TCCTTATTGT CAAGGTTTGA AGACAGTGAA AAACAAATAG ATTATAAGTC ATTTTTCTCT 
GCCCTGAACT GGAGAAAGAA TCCAGTGCCT GAATTGCAAC CAGCATCATA CCTTAAAGAG 
AGATGTGAAG ATGTTTGGCT TGGTATGCCA TCACCTATTC CTGCGAAATA CATTGACTAC 
TGGACCTTTT TGAAGGACGC GTTTGGCTTA GAGGAGGAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EFHC2 ( XM_024452453.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308221.1 Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu106284
Clone ID Related Accession (Same CDS sequence)	XM_024452453.1
Accession Version	XM_024452453.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	EF-hand domain-containing family member C2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTTGG TGAGTGATGA AAAGCCTGGA ATAGGTGGAG AACCACTTCT GGGGCAAAAG 
ATAAAGCCTA AATGTAGCAT ATATCCTAAA GGAGATGGAA GTGATGTACC ATCATGGGTA 
GCCTTTGATA AACAGGTATT ATCTTTTGAT GCCTATTTGG AAGAGGAAGT ACTTGATAAA 
AGCCAAACCA ACTACAGAAT AAGATACTAT AAAATCTACT TCTACCCTGA AGATGACACA 
ATTCAAGTAA ATGAACCAGA GGTGAAAAAT AGTGGATTAC TTCAAGGGAC TTCTATCCGG 
CGTCATCGGA TTACTCTTCC GCCTCCTGAT GAGGATCAGT TTTATACTGT GTATCATTTT 
AATGTCGGCA CAGAGGTTGT CTTCTATGGC CGGACATTCA AGATTTATGA CTGTGATGCA 
TTCACAAGAA ACTTTTTGAG GAAAATAGGG GTCAAAGTGA ATCCCCCAGT GCAATGTCCA 
GAAGATCCTT ACATGAAGAT TCGGAGAGAG GTTGTAGAAC ACGTAGAGCC CTTACGTCCC 
TACGAATCCC TCGACACCCT GAAACAGTTC CTCCAGTATC ATGGCAAGAT TTTGTGTTTC 
TTCTGCCTGT GGGATGACTC AGTCTCAATG TTTGGAGACC GTAGAGAACT CATCCTGCAT 
TACTTCTTGT GTGATGATAC TATTGAAATC AAAGAATTGC TTCCACACAG CTCAGGCCGA 
GATGCTCTAA AAATGTTCCT CCGGAGGAGT AAGCTACCCA AGAATTGCCC ACCTAGAGTC 
TATCAACCAG GCCAGATAAC AGATCGAGCA GTTCTCAATT CATATGGTGA CTTTATAAAG 
AACCAAGCGG ATGGCTACCT GTTCGATAGA TATAAGCTAG GAAAAGTAGA CCAAGAGTTT 
TACAAAGATA GTGACCTGTC CCTAGGAGTC ACCATCAATG TGTGGGGAAG AAAAGTGCTC 
CTTTATGACT GTGATGAATT TACGAAGTCT TATTATAAGT CTAAATATGG AATTGAGAAC 
TTTACCTCAG TTTCATGCAA GCCTCCTTCT CCTCCTCCAA AAATAGAAAG GAAATTTCCA 
CCTTACAACG GTTTTGGTTC TGAAGAGGAT TCTCTCCGTA ACTGCATAGA CCTCAAGCCC 
ACACCTCATC GGAGGAACTT CAAGAAGTTT ATGGAAAAAG ACAGCTATGG CTCCAAAAGC 
AATATACTCC GTTTTTTTGC AAAACTAGTC ACAGACAAAT GTGTTGACTT GGACAGGATG 
TTTGTTATTT CATATTATCT CGGTGATGAC ACCATTTCAG TGTTTGAACC TATAGAGAGG 
AATTCAGGAA TTGCTGGTGG GATGTTCTTG AAAAGAAGTC GCGTTAAGAA GCCTGGACAA 
GAAGTCTTTA AAAGTGAACT ATCTGAATAT ATCAAGGCCG AGGAGCTGTA CATTGGAGTC 
ACGGTGAATG TGAATGGTTA CCTATTTCGT TTGCTCAATG CTGATGAGTA TACCTTAAAC 
TACATGGAGC AGAATACAGA TAAGTATCCT TTCAGTAACC TCAAACTTGC CCTACAAAAG 
CTGAAGCAAG AAGAAGGAAA ATCCAGAGAG CTCAAGCAGG TATTTAAAGC TGCTGACTCT 
AAGCACACAA ATATGGTGGA TTATAATACA TTCAGAGACA TATTGATGTC TTTGACTGTT 
GGAAACCTTG CAGAGCAAGA ATTTGTAACC ATTGCACGTC ACTACCGTGT GCCTGAGGGC 
ACATGTTCAG ATATGGATTT CTTAATCGCA CTGGCCCACG AAAAGTTCAA GAAAAATATG 
TTTGAGAATT TCGACACTTT CATTTATTCC TGTGTGTATG AAGATCGAGA AAAAAAAAAT 
GTATTACCCA CCAAAGACAT TAAAAGGCTG TGCAAATCCT CCAGATTACC TTTGAGTGAT 
GATCTTCTAG AATCCTTATT GTCAAGGTTT GAAGACAGTG AAAAACAAAT AGATTATAAG 
TCATTTTTCT CTGCCCTGAA CTGGAGAAAG AATCCAGTGC CTGAATTGCA ACCAGCATCA 
TACCTTAAAG AGAGATGTGA AGATGTTTGG CTTGGTATGC CATCACCTAT TCCTGCGAAA 
TACATTGACT ACTGGACCTT TTTGAAGGAC GCGTTTGGCT TAGAGGAGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308221.1
CDS	162..2315
Translation	MMLVSDEKPGIGGEPLLGQKIKPKCSIYPKGDGSDVPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIRYYKIYFYPEDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVFYGRTFKIYDCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPYESLDTLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDTFIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSALNWRKNPVPELQPASYLKERCEDVWLGMPSPIPAKYIDYWTFLKDAFGLEEE

Target ORF information:

RefSeq Version	XM_024452453.1
Organism	Homo sapiens(human)
Definition	Homo sapiens EF-hand domain containing 2 (EFHC2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452453.1

ORF Insert Sequence:

ATGATGTTGG TGAGTGATGA AAAGCCTGGA ATAGGTGGAG AACCACTTCT GGGGCAAAAG 
ATAAAGCCTA AATGTAGCAT ATATCCTAAA GGAGATGGAA GTGATGTACC ATCATGGGTA 
GCCTTTGATA AACAGGTATT ATCTTTTGAT GCCTATTTGG AAGAGGAAGT ACTTGATAAA 
AGCCAAACCA ACTACAGAAT AAGATACTAT AAAATCTACT TCTACCCTGA AGATGACACA 
ATTCAAGTAA ATGAACCAGA GGTGAAAAAT AGTGGATTAC TTCAAGGGAC TTCTATCCGG 
CGTCATCGGA TTACTCTTCC GCCTCCTGAT GAGGATCAGT TTTATACTGT GTATCATTTT 
AATGTCGGCA CAGAGGTTGT CTTCTATGGC CGGACATTCA AGATTTATGA CTGTGATGCA 
TTCACAAGAA ACTTTTTGAG GAAAATAGGG GTCAAAGTGA ATCCCCCAGT GCAATGTCCA 
GAAGATCCTT ACATGAAGAT TCGGAGAGAG GTTGTAGAAC ACGTAGAGCC CTTACGTCCC 
TACGAATCCC TCGACACCCT GAAACAGTTC CTCCAGTATC ATGGCAAGAT TTTGTGTTTC 
TTCTGCCTGT GGGATGACTC AGTCTCAATG TTTGGAGACC GTAGAGAACT CATCCTGCAT 
TACTTCTTGT GTGATGATAC TATTGAAATC AAAGAATTGC TTCCACACAG CTCAGGCCGA 
GATGCTCTAA AAATGTTCCT CCGGAGGAGT AAGCTACCCA AGAATTGCCC ACCTAGAGTC 
TATCAACCAG GCCAGATAAC AGATCGAGCA GTTCTCAATT CATATGGTGA CTTTATAAAG 
AACCAAGCGG ATGGCTACCT GTTCGATAGA TATAAGCTAG GAAAAGTAGA CCAAGAGTTT 
TACAAAGATA GTGACCTGTC CCTAGGAGTC ACCATCAATG TGTGGGGAAG AAAAGTGCTC 
CTTTATGACT GTGATGAATT TACGAAGTCT TATTATAAGT CTAAATATGG AATTGAGAAC 
TTTACCTCAG TTTCATGCAA GCCTCCTTCT CCTCCTCCAA AAATAGAAAG GAAATTTCCA 
CCTTACAACG GTTTTGGTTC TGAAGAGGAT TCTCTCCGTA ACTGCATAGA CCTCAAGCCC 
ACACCTCATC GGAGGAACTT CAAGAAGTTT ATGGAAAAAG ACAGCTATGG CTCCAAAAGC 
AATATACTCC GTTTTTTTGC AAAACTAGTC ACAGACAAAT GTGTTGACTT GGACAGGATG 
TTTGTTATTT CATATTATCT CGGTGATGAC ACCATTTCAG TGTTTGAACC TATAGAGAGG 
AATTCAGGAA TTGCTGGTGG GATGTTCTTG AAAAGAAGTC GCGTTAAGAA GCCTGGACAA 
GAAGTCTTTA AAAGTGAACT ATCTGAATAT ATCAAGGCCG AGGAGCTGTA CATTGGAGTC 
ACGGTGAATG TGAATGGTTA CCTATTTCGT TTGCTCAATG CTGATGAGTA TACCTTAAAC 
TACATGGAGC AGAATACAGA TAAGTATCCT TTCAGTAACC TCAAACTTGC CCTACAAAAG 
CTGAAGCAAG AAGAAGGAAA ATCCAGAGAG CTCAAGCAGG TATTTAAAGC TGCTGACTCT 
AAGCACACAA ATATGGTGGA TTATAATACA TTCAGAGACA TATTGATGTC TTTGACTGTT 
GGAAACCTTG CAGAGCAAGA ATTTGTAACC ATTGCACGTC ACTACCGTGT GCCTGAGGGC 
ACATGTTCAG ATATGGATTT CTTAATCGCA CTGGCCCACG AAAAGTTCAA GAAAAATATG 
TTTGAGAATT TCGACACTTT CATTTATTCC TGTGTGTATG AAGATCGAGA AAAAAAAAAT 
GTATTACCCA CCAAAGACAT TAAAAGGCTG TGCAAATCCT CCAGATTACC TTTGAGTGAT 
GATCTTCTAG AATCCTTATT GTCAAGGTTT GAAGACAGTG AAAAACAAAT AGATTATAAG 
TCATTTTTCT CTGCCCTGAA CTGGAGAAAG AATCCAGTGC CTGAATTGCA ACCAGCATCA 
TACCTTAAAG AGAGATGTGA AGATGTTTGG CTTGGTATGC CATCACCTAT TCCTGCGAAA 
TACATTGACT ACTGGACCTT TTTGAAGGAC GCGTTTGGCT TAGAGGAGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits.
Journal of genetics96(6)1015-1020(2017 Dec)
Jia B,Huang L,Chen Y,Liu S,Chen C,Xiong K,Song L,Zhou Y,Yang X,Zhong M

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

No relation between EFHC2 gene polymorphism and Idiopathic generalized epilepsy.
African health sciences15(4)1204-10(2015 Dec)
Berrin T,Hikmet Y,G?l?en V,Ferda B,Erdal B,Ece O

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.
PloS one10(6)e0131604(2015)
Startin CM,Fiorentini C,de Haan M,Skuse DH

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EFHC2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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