Gene Symbol | LHX3 |
Entrez Gene ID | 8022 |
Full Name | LIM homeobox 3 |
Synonyms | CPHD3,LIM3,M2-LHX3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of a large family of proteins which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene cause combined pituitary hormone deficiency 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]. |
Disorder MIM: | |
Disorder Html: | Pituitary hormone deficiency, combined, 3, 221750 (3) |