CCDC170 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCDC170
Entrez Gene ID	80129
Full Name	coiled-coil domain containing 170
Synonyms	C6orf97,bA282P11.1
General protein information	Preferred Names coiled-coil domain containing 170 Names coiled-coil domain-containing protein 170
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q25.1
Summary	The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found. [provided by RefSeq, May 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_025059.3	NP_079335.2	coiled-coil domain-containing protein 170
XM_011536148.2	XP_011534450.1	coiled-coil domain-containing protein 170 isoform X2
NM_025059.4	NP_079335.2	coiled-coil domain-containing protein 170
XM_011536147.2	XP_011534449.1	coiled-coil domain-containing protein 170 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCDC170	NP_079335.2
Mus musculus (house mouse)	Ccdc170	NP_001182601.1
Xenopus tropicalis (tropical clawed frog)	ccdc170	XP_002936421.2
Bos taurus (cattle)	CCDC170	XP_005211117.1
Rattus norvegicus (Norway rat)	Ccdc170	XP_214760.4
Drosophila melanogaster (fruit fly)	CG43338	NP_724119.1
Gallus gallus (chicken)	C6ORF97	XP_004935685.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007734	XP_317785.3
Pan troglodytes (chimpanzee)	CCDC170	XP_527540.3
	LOC712320	XP_001101266.2
Canis lupus familiaris (dog)	CCDC170	XP_005615574.1
Danio rerio (zebrafish)	ccdc170	XP_003200359.2

Gene Ontology
Bibliography

Related articles in PubMed

The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network.
Jiang P, Li Y, Poleshko A, Medvedeva V, Baulina N, Zhang Y, Zhou Y, Slater CM, Pellegrin T, Wasserman J, Lindy M, Efimov A, Daly M, Katz RA, Chen X
EBioMedicine2228-43(2017 Aug)

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J, Wang Q, Hopper JL, Southey MC, Broeks A, Schmidt MK, Lophatananon A, Muir K, Beckmann MW, Fasching PA, Dos-Santos-Silva I, Peto J, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Gu?nel P, Truong T, Bojesen SE, Flyger H, Gonz?lez-Neira A, Perez JI, Anton-Culver H, Eunjung L, Arndt V, Brenner H, Meindl A, Schmutzler RK, Brauch H, Hamann U, Aittom?ki K, Blomqvist C, Ito H, Matsuo K, Bogdanova N, D?rk T, Lindblom A, Margolin S, Kosma VM, Mannermaa A, Tseng CC, Wu AH, Lambrechts D, Wildiers H, Chang-Claude J, Rudolph A, Peterlongo P, Radice P, Olson JE, Giles GG, Milne RL, Haiman CA, Henderson BE, Goldberg MS, Teo SH, Yip CH, Nord S, Borresen-Dale AL, Kristensen V, Long J, Zheng W, Pylk?s K, Winqvist R, Andrulis IL, Knight JA, Devilee P, Seynaeve C, Figueroa J, Sherman ME, Czene K, Darabi H, Hollestelle A, van den Ouweland AM, Humphreys K, Gao YT, Shu XO, Cox A, Cross SS, Blot W, Cai Q, Ghoussaini M, Perkins BJ, Shah M, Choi JY, Kang D, Lee SC, Hartman M, Kabisch M, Torres D, Jakubowska A, Lubinski J, Brennan P, Sangrajrang S, Ambrosone CB, Toland AE, Shen CY, Wu PE, Orr N, Swerdlow A, McGuffog L, Healey S, Lee A, Kapuscinski M, John EM, Terry MB, Daly MB, Goldgar DE, Buys SS, Janavicius R, Tihomirova L, Tung N, Dorfling CM, van Rensburg EJ, Neuhausen SL, Ejlertsen B, Hansen TV, Osorio A, Benitez J, Rando R, Weitzel JN, Bonanni B, Peissel B, Manoukian S, Papi L, Ottini L, Konstantopoulou I, Apostolou P, Garber J, Rashid MU, Frost D, , Izatt L, Ellis S, Godwin AK, Arnold N, Niederacher D, Rhiem K, Bogdanova-Markov N, Sagne C, Stoppa-Lyonnet D, Damiola F, , Sinilnikova OM, Mazoyer S, Isaacs C, Claes KB, De Leeneer K, de la Hoya M, Caldes T, Nevanlinna H, Khan S, Mensenkamp AR, , Hooning MJ, Rookus MA, Kwong A, Olah E, Diez O, Brunet J, Pujana MA, Gronwald J, Huzarski T, Barkardottir RB, Laframboise R, Soucy P, Montagna M, Agata S, Teixeira MR, , Park SK, Lindor N, Couch FJ, Tischkowitz M, Foretova L, Vijai J, Offit K, Singer CF, Rappaport C, Phelan CM, Greene MH, Mai PL, Rennert G, Imyanitov EN, Hulick PJ, Phillips KA, Piedmonte M, Mulligan AM, Glendon G, Bojesen A, Thomassen M, Caligo MA, Yoon SY, Friedman E, Laitman Y, Borg A, von Wachenfeldt A, Ehrencrona H, Rantala J, Olopade OI, Ganz PA, Nussbaum RL, Gayther SA, Nathanson KL, Domchek SM, Arun BK, Mitchell G, Karlan BY, Lester J, Maskarinec G, Woolcott C, Scott C, Stone J, Apicella C, Tamimi R, Luben R, Khaw KT, Helland ?, Haakensen V, Dowsett M, Pharoah PD, Simard J, Hall P, Garc?a-Closas M, Vachon C, Chenevix-Trench G, Antoniou AC, Easton DF, Edwards SL
Nature genetics48(4)374-86(2016 Apr)

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.
Mullin BH, Walsh JP, Zheng HF, Brown SJ, Surdulescu GL, Curtis C, Breen G, Dudbridge F, Richards JB, Spector TD, Wilson SG
BMC genomics17136(2016 Feb)

C6ORF97-ESR1 breast cancer susceptibility locus: influence on progression and survival in breast cancer patients.
Yamamoto-Ibusuki M, Yamamoto Y, Fujiwara S, Sueta A, Yamamoto S, Hayashi M, Tomiguchi M, Takeshita T, Iwase H
European journal of human genetics : EJHG23(7)949-56(2015 Jul)

Current evidence on the association between rs3757318 of C6orf97 and breast cancer risk: a meta-analysis.
Hong Y, Chen XQ, Li JY, Liu C, Shen N, Zhu BB, Gong J, Chen W
Asian Pacific journal of cancer prevention : APJCP15(19)8051-5(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis]
Title: Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

Genetic variation at the WLS and CCDC170/ESR1 loci were found to be significantly associated with bone mineral density
Title: Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.

Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients.
Title: C6ORF97-ESR1 breast cancer susceptibility locus: influence on progression and survival in breast cancer patients.

ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers
Title: Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.

Variation in rs3757318 of C6orf97 is associated with breast cancer risk.
Title: Current evidence on the association between rs3757318 of C6orf97 and breast cancer risk: a meta-analysis.

The following CCDC170 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCDC170 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23146	NM_025059.4 Latest version!	Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu72576	XM_011536148.2 Latest version!	Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu72575	XM_011536147.2 Latest version!	Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu23146	NM_025059.3	Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCDC170 ( NM_025059.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079335.2 Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.

Price & Availability↑

CloneID	OHu23146
Clone ID Related Accession (Same CDS sequence)	NM_025059.3 , NM_025059.4
Accession Version	NM_025059.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2148bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 170
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB232703.1, BC060803.1, AK225330.1 and AL359494.17. This sequence is a reference standard in the RefSeqGene project. On Jan 22, 2009 this sequence version replaced NM_025059.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035003.2, SRR1803616.68769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCCTGG ACTGCACCAG CCATATCGCG CTGGGTGCCG CTTCGCCAGC GCCCGAGGAA 
ACTTACGATC ATCTTTCGGA AGTCCCGGTC ACGCGGGAGC AGTTAAACCA CTATCGGAAT 
GTGGCTCAAA ATGCTCGAAG TGAACTTGCA GCAACTTTGG TCAAATTTGA ATGTGCTCAG 
TCTGAGCTTC AAGACCTCCG ATCCAAGATG CTTTCTAAAG AAGTCTCCTG TCAAGAACTG 
AAAGCTGAAA TGGAGAGCTA CAAGGAAAAC AATGCCAGAA AATCATCTCT CCTTACCTCT 
TTGAGAGACA GAGTTCAGGA ACTAGAAGAA GAATCAGCAG CACTTTCCAC TTCTAAAATC 
AGAACAGAAA TCACAGCTCA CGCTGCAATC AAGGAGAACC AGGAATTAAA GAAGAAAGTT 
GTAGAGTTAA ATGAAAAATT ACAAAAGTGT TCAAAAGAAA ATGAGGAGAA TAAGAAACAA 
GTTTCAAAGA ATTGCAGGAA ACATGAGGAA TTTCTGACTC AACTGCGTGA CTGCTTGGAT 
CCAGATGAGA GGAATGACAA GGCATCAGAT GAAGATTTAA TTTTAAAGCT TAGAGACCTG 
CGCAAAGAAA ATGAATTCGT GAAAGGACAA ATTGTTATTC TTGAAGAGAC TATAAATGTC 
CATGAGATGG AAGCAAAAGC TAGCAGAGAA ACGATCATGA GGCTGGCTTC AGAAGTCAAC 
AGAGAGCAGA AAAAAGCTGC CTCCTGTACT GAAGAGAAAG AGAAGCTGAA CCAGGACCTG 
CTCAGTGCTG TAGAAGCAAA AGAAGCTCTT GAAAGGGAAG TTAAGATCTT CCAAGAAAGG 
CTGCTTGCTG GCCAGCAGGT CTGGGATGCC TCAAAGCAGG AAGTGAGCCT CCTGAAGAAA 
AGCTCTTCTG AGTTGGAGAA GAGTTTGAAG GCCAGTCAGG ATGCAGTCAC AACCTCACAA 
AGCCAGTACT TCTCATTTAG GGAGAAAATC GCAGCCCTCC TTAGGGGCAG ATTGAGCATG 
ACTGGGTCCA CTGAGGACAC CATTTTGGAG AAGATTCGAG AAATGGACAG CCGGGAAGAA 
AGCAGGGACC GGATGGTCTC CCAGCTTGAA GCCCAAATAT CTGAGCTTGT TGAACAGTTG 
GGAAAGGAGT CTGGGTTTCA CCAGAAAGCT CTCCAGAGGG CCCAGAAAGC AGAGAATATG 
TTGGAGACTC TTCAGGGTCA GCTGACACAC CTGGAGGCAG AGCTGGTTTC TGGAGGTGTT 
TTGCGAGACA ACTTGAATTT TGAGAAACAA AAATATCTTA AATTTCTGGA TCAGCTTTCT 
CAGAAAATGA AGTTGGACCA GATGGCTGCC GAACTTGGCT TTGACATGCG GCTGGACGTG 
GTTTTAGCTC GAACAGAGCA GCTGGTTCGT CTTGAGAGCA ATGCAGTCAT TGAGAACAAG 
ACCATTGCCC ACAATTTGCA GAGAAAGCTA AAGACACAGA AAGAGAGACT GGAGAGCAAA 
GAATTACACA TGAGCCTCCT CCGGCAGAAA ATAGCCCAGC TGGAGGAGGA GAAGCAGGCA 
CGCACGGCCT TGGTGGTTGA GAGGGACAAC GCGCATCTTA CCATCAGGAA CTTGCAGAAG 
AAGGTGGAGA GGCTGCAGAA AGAGCTGAAC ACGTGTCGAG ACTTGCACAC CGAGCTCAAA 
GCCAAACTGG CCGACACCAA TGAACTGAAG ATTAAAACTT TGGAACAGAC TAAAGCCATT 
GAAGATCTAA ACAAATCCAG AGACCAACTG GAGAAGATGA AGGAGAAAGC TGAGAAAAAG 
CTCATGTCTG TCAAGTCAGA ACTGGATACC ACAGAACATG AGGCTAAGGA GAATAAAGAA 
AGGGCCAGAA ACATGATAGA AGTGGTAACC AGTGAAATGA AGACACTAAA AAAATCTCTG 
GAAGAAGCAG AAAAGAGAGA AAAGCAGCTG GCAGACTTCA GGGAGGTGGT GTCGCAGATG 
CTAGGCTTGA ACGTGACCAG CCTTGCTCTT CCTGATTATG AAATCATCAA GTGTCTTGAA 
AGATTGGTCC ATTCACATCA GCATCACTTT GTTACCTGTG CCTGCCTCAA AGATGTGACT 
ACTGGGCAAG AGAGGCACCC ACAAGGCCAT TTACAGCTTC TTCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079335.2
CDS	90..2237
Translation	MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH

Target ORF information:

RefSeq Version	NM_025059.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025059.3

ORF Insert Sequence:

ATGAGCCTGG ACTGCACCAG CCATATCGCG CTGGGTGCCG CTTCGCCAGC GCCCGAGGAA 
ACTTACGATC ATCTTTCGGA AGTCCCGGTC ACGCGGGAGC AGTTAAACCA CTATCGGAAT 
GTGGCTCAAA ATGCTCGAAG TGAACTTGCA GCAACTTTGG TCAAATTTGA ATGTGCTCAG 
TCTGAGCTTC AAGACCTCCG ATCCAAGATG CTTTCTAAAG AAGTCTCCTG TCAAGAACTG 
AAAGCTGAAA TGGAGAGCTA CAAGGAAAAC AATGCCAGAA AATCATCTCT CCTTACCTCT 
TTGAGAGACA GAGTTCAGGA ACTAGAAGAA GAATCAGCAG CACTTTCCAC TTCTAAAATC 
AGAACAGAAA TCACAGCTCA CGCTGCAATC AAGGAGAACC AGGAATTAAA GAAGAAAGTT 
GTAGAGTTAA ATGAAAAATT ACAAAAGTGT TCAAAAGAAA ATGAGGAGAA TAAGAAACAA 
GTTTCAAAGA ATTGCAGGAA ACATGAGGAA TTTCTGACTC AACTGCGTGA CTGCTTGGAT 
CCAGATGAGA GGAATGACAA GGCATCAGAT GAAGATTTAA TTTTAAAGCT TAGAGACCTG 
CGCAAAGAAA ATGAATTCGT GAAAGGACAA ATTGTTATTC TTGAAGAGAC TATAAATGTC 
CATGAGATGG AAGCAAAAGC TAGCAGAGAA ACGATCATGA GGCTGGCTTC AGAAGTCAAC 
AGAGAGCAGA AAAAAGCTGC CTCCTGTACT GAAGAGAAAG AGAAGCTGAA CCAGGACCTG 
CTCAGTGCTG TAGAAGCAAA AGAAGCTCTT GAAAGGGAAG TTAAGATCTT CCAAGAAAGG 
CTGCTTGCTG GCCAGCAGGT CTGGGATGCC TCAAAGCAGG AAGTGAGCCT CCTGAAGAAA 
AGCTCTTCTG AGTTGGAGAA GAGTTTGAAG GCCAGTCAGG ATGCAGTCAC AACCTCACAA 
AGCCAGTACT TCTCATTTAG GGAGAAAATC GCAGCCCTCC TTAGGGGCAG ATTGAGCATG 
ACTGGGTCCA CTGAGGACAC CATTTTGGAG AAGATTCGAG AAATGGACAG CCGGGAAGAA 
AGCAGGGACC GGATGGTCTC CCAGCTTGAA GCCCAAATAT CTGAGCTTGT TGAACAGTTG 
GGAAAGGAGT CTGGGTTTCA CCAGAAAGCT CTCCAGAGGG CCCAGAAAGC AGAGAATATG 
TTGGAGACTC TTCAGGGTCA GCTGACACAC CTGGAGGCAG AGCTGGTTTC TGGAGGTGTT 
TTGCGAGACA ACTTGAATTT TGAGAAACAA AAATATCTTA AATTTCTGGA TCAGCTTTCT 
CAGAAAATGA AGTTGGACCA GATGGCTGCC GAACTTGGCT TTGACATGCG GCTGGACGTG 
GTTTTAGCTC GAACAGAGCA GCTGGTTCGT CTTGAGAGCA ATGCAGTCAT TGAGAACAAG 
ACCATTGCCC ACAATTTGCA GAGAAAGCTA AAGACACAGA AAGAGAGACT GGAGAGCAAA 
GAATTACACA TGAGCCTCCT CCGGCAGAAA ATAGCCCAGC TGGAGGAGGA GAAGCAGGCA 
CGCACGGCCT TGGTGGTTGA GAGGGACAAC GCGCATCTTA CCATCAGGAA CTTGCAGAAG 
AAGGTGGAGA GGCTGCAGAA AGAGCTGAAC ACGTGTCGAG ACTTGCACAC CGAGCTCAAA 
GCCAAACTGG CCGACACCAA TGAACTGAAG ATTAAAACTT TGGAACAGAC TAAAGCCATT 
GAAGATCTAA ACAAATCCAG AGACCAACTG GAGAAGATGA AGGAGAAAGC TGAGAAAAAG 
CTCATGTCTG TCAAGTCAGA ACTGGATACC ACAGAACATG AGGCTAAGGA GAATAAAGAA 
AGGGCCAGAA ACATGATAGA AGTGGTAACC AGTGAAATGA AGACACTAAA AAAATCTCTG 
GAAGAAGCAG AAAAGAGAGA AAAGCAGCTG GCAGACTTCA GGGAGGTGGT GTCGCAGATG 
CTAGGCTTGA ACGTGACCAG CCTTGCTCTT CCTGATTATG AAATCATCAA GTGTCTTGAA 
AGATTGGTCC ATTCACATCA GCATCACTTT GTTACCTGTG CCTGCCTCAA AGATGTGACT 
ACTGGGCAAG AGAGGCACCC ACAAGGCCAT TTACAGCTTC TTCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC170 ( NM_025059.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_079335.2 Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.

Price & Availability↑

CloneID	OHu23146
Clone ID Related Accession (Same CDS sequence)	NM_025059.3 , NM_025059.4
Accession Version	NM_025059.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2148bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 170
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL590543.8, DB232703.1, BC060803.1, AK225330.1 and AL359494.17. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_025059.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035003.2, SRR1803616.68769.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000239374.8/ ENSP00000239374.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCCTGG ACTGCACCAG CCATATCGCG CTGGGTGCCG CTTCGCCAGC GCCCGAGGAA 
ACTTACGATC ATCTTTCGGA AGTCCCGGTC ACGCGGGAGC AGTTAAACCA CTATCGGAAT 
GTGGCTCAAA ATGCTCGAAG TGAACTTGCA GCAACTTTGG TCAAATTTGA ATGTGCTCAG 
TCTGAGCTTC AAGACCTCCG ATCCAAGATG CTTTCTAAAG AAGTCTCCTG TCAAGAACTG 
AAAGCTGAAA TGGAGAGCTA CAAGGAAAAC AATGCCAGAA AATCATCTCT CCTTACCTCT 
TTGAGAGACA GAGTTCAGGA ACTAGAAGAA GAATCAGCAG CACTTTCCAC TTCTAAAATC 
AGAACAGAAA TCACAGCTCA CGCTGCAATC AAGGAGAACC AGGAATTAAA GAAGAAAGTT 
GTAGAGTTAA ATGAAAAATT ACAAAAGTGT TCAAAAGAAA ATGAGGAGAA TAAGAAACAA 
GTTTCAAAGA ATTGCAGGAA ACATGAGGAA TTTCTGACTC AACTGCGTGA CTGCTTGGAT 
CCAGATGAGA GGAATGACAA GGCATCAGAT GAAGATTTAA TTTTAAAGCT TAGAGACCTG 
CGCAAAGAAA ATGAATTCGT GAAAGGACAA ATTGTTATTC TTGAAGAGAC TATAAATGTC 
CATGAGATGG AAGCAAAAGC TAGCAGAGAA ACGATCATGA GGCTGGCTTC AGAAGTCAAC 
AGAGAGCAGA AAAAAGCTGC CTCCTGTACT GAAGAGAAAG AGAAGCTGAA CCAGGACCTG 
CTCAGTGCTG TAGAAGCAAA AGAAGCTCTT GAAAGGGAAG TTAAGATCTT CCAAGAAAGG 
CTGCTTGCTG GCCAGCAGGT CTGGGATGCC TCAAAGCAGG AAGTGAGCCT CCTGAAGAAA 
AGCTCTTCTG AGTTGGAGAA GAGTTTGAAG GCCAGTCAGG ATGCAGTCAC AACCTCACAA 
AGCCAGTACT TCTCATTTAG GGAGAAAATC GCAGCCCTCC TTAGGGGCAG ATTGAGCATG 
ACTGGGTCCA CTGAGGACAC CATTTTGGAG AAGATTCGAG AAATGGACAG CCGGGAAGAA 
AGCAGGGACC GGATGGTCTC CCAGCTTGAA GCCCAAATAT CTGAGCTTGT TGAACAGTTG 
GGAAAGGAGT CTGGGTTTCA CCAGAAAGCT CTCCAGAGGG CCCAGAAAGC AGAGAATATG 
TTGGAGACTC TTCAGGGTCA GCTGACACAC CTGGAGGCAG AGCTGGTTTC TGGAGGTGTT 
TTGCGAGACA ACTTGAATTT TGAGAAACAA AAATATCTTA AATTTCTGGA TCAGCTTTCT 
CAGAAAATGA AGTTGGACCA GATGGCTGCC GAACTTGGCT TTGACATGCG GCTGGACGTG 
GTTTTAGCTC GAACAGAGCA GCTGGTTCGT CTTGAGAGCA ATGCAGTCAT TGAGAACAAG 
ACCATTGCCC ACAATTTGCA GAGAAAGCTA AAGACACAGA AAGAGAGACT GGAGAGCAAA 
GAATTACACA TGAGCCTCCT CCGGCAGAAA ATAGCCCAGC TGGAGGAGGA GAAGCAGGCA 
CGCACGGCCT TGGTGGTTGA GAGGGACAAC GCGCATCTTA CCATCAGGAA CTTGCAGAAG 
AAGGTGGAGA GGCTGCAGAA AGAGCTGAAC ACGTGTCGAG ACTTGCACAC CGAGCTCAAA 
GCCAAACTGG CCGACACCAA TGAACTGAAG ATTAAAACTT TGGAACAGAC TAAAGCCATT 
GAAGATCTAA ACAAATCCAG AGACCAACTG GAGAAGATGA AGGAGAAAGC TGAGAAAAAG 
CTCATGTCTG TCAAGTCAGA ACTGGATACC ACAGAACATG AGGCTAAGGA GAATAAAGAA 
AGGGCCAGAA ACATGATAGA AGTGGTAACC AGTGAAATGA AGACACTAAA AAAATCTCTG 
GAAGAAGCAG AAAAGAGAGA AAAGCAGCTG GCAGACTTCA GGGAGGTGGT GTCGCAGATG 
CTAGGCTTGA ACGTGACCAG CCTTGCTCTT CCTGATTATG AAATCATCAA GTGTCTTGAA 
AGATTGGTCC ATTCACATCA GCATCACTTT GTTACCTGTG CCTGCCTCAA AGATGTGACT 
ACTGGGCAAG AGAGGCACCC ACAAGGCCAT TTACAGCTTC TTCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079335.2
CDS	113..2260
Translation	MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH

Target ORF information:

RefSeq Version	NM_025059.4
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 170 (CCDC170), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025059.4

ORF Insert Sequence:

ATGAGCCTGG ACTGCACCAG CCATATCGCG CTGGGTGCCG CTTCGCCAGC GCCCGAGGAA 
ACTTACGATC ATCTTTCGGA AGTCCCGGTC ACGCGGGAGC AGTTAAACCA CTATCGGAAT 
GTGGCTCAAA ATGCTCGAAG TGAACTTGCA GCAACTTTGG TCAAATTTGA ATGTGCTCAG 
TCTGAGCTTC AAGACCTCCG ATCCAAGATG CTTTCTAAAG AAGTCTCCTG TCAAGAACTG 
AAAGCTGAAA TGGAGAGCTA CAAGGAAAAC AATGCCAGAA AATCATCTCT CCTTACCTCT 
TTGAGAGACA GAGTTCAGGA ACTAGAAGAA GAATCAGCAG CACTTTCCAC TTCTAAAATC 
AGAACAGAAA TCACAGCTCA CGCTGCAATC AAGGAGAACC AGGAATTAAA GAAGAAAGTT 
GTAGAGTTAA ATGAAAAATT ACAAAAGTGT TCAAAAGAAA ATGAGGAGAA TAAGAAACAA 
GTTTCAAAGA ATTGCAGGAA ACATGAGGAA TTTCTGACTC AACTGCGTGA CTGCTTGGAT 
CCAGATGAGA GGAATGACAA GGCATCAGAT GAAGATTTAA TTTTAAAGCT TAGAGACCTG 
CGCAAAGAAA ATGAATTCGT GAAAGGACAA ATTGTTATTC TTGAAGAGAC TATAAATGTC 
CATGAGATGG AAGCAAAAGC TAGCAGAGAA ACGATCATGA GGCTGGCTTC AGAAGTCAAC 
AGAGAGCAGA AAAAAGCTGC CTCCTGTACT GAAGAGAAAG AGAAGCTGAA CCAGGACCTG 
CTCAGTGCTG TAGAAGCAAA AGAAGCTCTT GAAAGGGAAG TTAAGATCTT CCAAGAAAGG 
CTGCTTGCTG GCCAGCAGGT CTGGGATGCC TCAAAGCAGG AAGTGAGCCT CCTGAAGAAA 
AGCTCTTCTG AGTTGGAGAA GAGTTTGAAG GCCAGTCAGG ATGCAGTCAC AACCTCACAA 
AGCCAGTACT TCTCATTTAG GGAGAAAATC GCAGCCCTCC TTAGGGGCAG ATTGAGCATG 
ACTGGGTCCA CTGAGGACAC CATTTTGGAG AAGATTCGAG AAATGGACAG CCGGGAAGAA 
AGCAGGGACC GGATGGTCTC CCAGCTTGAA GCCCAAATAT CTGAGCTTGT TGAACAGTTG 
GGAAAGGAGT CTGGGTTTCA CCAGAAAGCT CTCCAGAGGG CCCAGAAAGC AGAGAATATG 
TTGGAGACTC TTCAGGGTCA GCTGACACAC CTGGAGGCAG AGCTGGTTTC TGGAGGTGTT 
TTGCGAGACA ACTTGAATTT TGAGAAACAA AAATATCTTA AATTTCTGGA TCAGCTTTCT 
CAGAAAATGA AGTTGGACCA GATGGCTGCC GAACTTGGCT TTGACATGCG GCTGGACGTG 
GTTTTAGCTC GAACAGAGCA GCTGGTTCGT CTTGAGAGCA ATGCAGTCAT TGAGAACAAG 
ACCATTGCCC ACAATTTGCA GAGAAAGCTA AAGACACAGA AAGAGAGACT GGAGAGCAAA 
GAATTACACA TGAGCCTCCT CCGGCAGAAA ATAGCCCAGC TGGAGGAGGA GAAGCAGGCA 
CGCACGGCCT TGGTGGTTGA GAGGGACAAC GCGCATCTTA CCATCAGGAA CTTGCAGAAG 
AAGGTGGAGA GGCTGCAGAA AGAGCTGAAC ACGTGTCGAG ACTTGCACAC CGAGCTCAAA 
GCCAAACTGG CCGACACCAA TGAACTGAAG ATTAAAACTT TGGAACAGAC TAAAGCCATT 
GAAGATCTAA ACAAATCCAG AGACCAACTG GAGAAGATGA AGGAGAAAGC TGAGAAAAAG 
CTCATGTCTG TCAAGTCAGA ACTGGATACC ACAGAACATG AGGCTAAGGA GAATAAAGAA 
AGGGCCAGAA ACATGATAGA AGTGGTAACC AGTGAAATGA AGACACTAAA AAAATCTCTG 
GAAGAAGCAG AAAAGAGAGA AAAGCAGCTG GCAGACTTCA GGGAGGTGGT GTCGCAGATG 
CTAGGCTTGA ACGTGACCAG CCTTGCTCTT CCTGATTATG AAATCATCAA GTGTCTTGAA 
AGATTGGTCC ATTCACATCA GCATCACTTT GTTACCTGTG CCTGCCTCAA AGATGTGACT 
ACTGGGCAAG AGAGGCACCC ACAAGGCCAT TTACAGCTTC TTCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC170 ( XM_011536148.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534450.1 Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu72576
Clone ID Related Accession (Same CDS sequence)	XM_011536148.2
Accession Version	XM_011536148.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1965bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 170 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536148.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTCAGA TGGAAACAGG ACCAGAGGGT TCAGTCTGCA GCCCACAGGC CAAACCCACC 
AAATCTGCTC TGCAGGAAAC TTACGATCAT CTTTCGGAAG TCCCGGTCAC GCGGGAGCAG 
TTAAACCACT ATCGGAATGT GGCTCAAAAT GCTCGAAGTG AACTTGCAGC AACTTTGGTC 
AAATTTGAAT GTGCTCAGTC TGAGCTTCAA GACCTCCGAT CCAAGATGCT TTCTAAAGAA 
GTCTCCTGTC AAGAACTGAA AGCTGAAATG GAGAGCTACA AGGAAAACAA TGCCAGAAAA 
TCATCTCTCC TTACCTCTTT GAGAGACAGA GTTCAGGAAC TAGAAGAAGA ATCAGCAGCA 
CTTTCCACTT CTAAAATCAG AACAGAAATC ACAGCTCACG CTGCAATCAA GGAGAACCAG 
GAATTAAAGA AGAAAGTTGT AGAGTTAAAT GAAAAATTAC AAAAGTGTTC AAAAGAAAAT 
GAGGAGAATA AGAAACAAGT TTCAAAGAAT TGCAGGAAAC ATGAGGAATT TCTGACTCAA 
CTGCGTGACT GCTTGGATCC AGATGAGAGG AATGACAAGG CATCAGATGA AGATTTAATT 
TTAAAGCTTA GAGACCTGCG CAAAGAAAAT GAATTCGTGA AAGGACAAAT TGTTATTCTT 
GAAGAGACTA TAAATGTCCA TGAGATGGAA GCAAAAGCTA GCAGAGAAAC GATCATGAGG 
CTGGCTTCAG AAGTCAACAG AGAGCAGAAA AAAGCTGCCT CCTGTACTGA AGAGAAAGAG 
AAGCTGAACC AGGACCTGCT CAGTGCTGTA GAAGCAAAAG AAGCTCTTGA AAGGGAAGTT 
AAGATCTTCC AAGAAAGGCT GCTTGCTGGC CAGCAGGTCT GGGATGCCTC AAAGCAGGAA 
GTGAGCCTCC TGAAGAAAAG CTCTTCTGAG TTGGAGAAGA GTTTGAAGGC CAGTCAGGAT 
GCAGTCACAA CCTCACAAAG CCAGTACTTC TCATTTAGGG AGAAAATCGC AGCCCTCCTT 
AGGGGCAGAT TGAGCATGAC TGGGTCCACT GAGGACACCA TTTTGGAGAA GATTCGAGAA 
ATGGACAGCC GGGAAGAAAG CAGGGACCGG TATCTTAAAT TTCTGGATCA GCTTTCTCAG 
AAAATGAAGT TGGACCAGAT GGCTGCCGAA CTTGGCTTTG ACATGCGGCT GGACGTGGTT 
TTAGCTCGAA CAGAGCAGCT GGTTCGTCTT GAGAGCAATG CAGTCATTGA GAACAAGACC 
ATTGCCCACA ATTTGCAGAG AAAGCTAAAG ACACAGAAAG AGAGACTGGA GAGCAAAGAA 
TTACACATGA GCCTCCTCCG GCAGAAAATA GCCCAGCTGG AGGAGGAGAA GCAGGCACGC 
ACGGCCTTGG TGGTTGAGAG GGACAACGCG CATCTTACCA TCAGGAACTT GCAGAAGAAG 
GTGGAGAGGC TGCAGAAAGA GCTGAACACG TGTCGAGACT TGCACACCGA GCTCAAAGCC 
AAACTGGCCG ACACCAATGA ACTGAAGATT AAAACTTTGG AACAGACTAA AGCCATTGAA 
GATCTAAACA AATCCAGAGA CCAACTGGAG AAGATGAAGG AGAAAGCTGA GAAAAAGCTC 
ATGTCTGTCA AGTCAGAACT GGATACCACA GAACATGAGG CTAAGGAGAA TAAAGAAAGG 
GCCAGAAACA TGATAGAAGT GGTAACCAGT GAAATGAAGA CACTAAAAAA ATCTCTGGAA 
GAAGCAGAAA AGAGAGAAAA GCAGCTGGCA GACTTCAGGG AGGTGGTGTC GCAGATGCTA 
GGCTTGAACG TGACCAGCCT TGCTCTTCCT GATTATGAAA TCATCAAGTG TCTTGAAAGA 
TTGGTCCATT CACATCAGCA TCACTTTGTT ACCTGTGCCT GCCTCAAAGA TGTGACTACT 
GGGCAAGAGA GGCACCCACA AGGCCATTTA CAGCTTCTTC ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534450.1
CDS	113..2077
Translation	MSQMETGPEGSVCSPQAKPTKSALQETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH

Target ORF information:

RefSeq Version	XM_011536148.2
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011536148.2

ORF Insert Sequence:

ATGAGTCAGA TGGAAACAGG ACCAGAGGGT TCAGTCTGCA GCCCACAGGC CAAACCCACC 
AAATCTGCTC TGCAGGAAAC TTACGATCAT CTTTCGGAAG TCCCGGTCAC GCGGGAGCAG 
TTAAACCACT ATCGGAATGT GGCTCAAAAT GCTCGAAGTG AACTTGCAGC AACTTTGGTC 
AAATTTGAAT GTGCTCAGTC TGAGCTTCAA GACCTCCGAT CCAAGATGCT TTCTAAAGAA 
GTCTCCTGTC AAGAACTGAA AGCTGAAATG GAGAGCTACA AGGAAAACAA TGCCAGAAAA 
TCATCTCTCC TTACCTCTTT GAGAGACAGA GTTCAGGAAC TAGAAGAAGA ATCAGCAGCA 
CTTTCCACTT CTAAAATCAG AACAGAAATC ACAGCTCACG CTGCAATCAA GGAGAACCAG 
GAATTAAAGA AGAAAGTTGT AGAGTTAAAT GAAAAATTAC AAAAGTGTTC AAAAGAAAAT 
GAGGAGAATA AGAAACAAGT TTCAAAGAAT TGCAGGAAAC ATGAGGAATT TCTGACTCAA 
CTGCGTGACT GCTTGGATCC AGATGAGAGG AATGACAAGG CATCAGATGA AGATTTAATT 
TTAAAGCTTA GAGACCTGCG CAAAGAAAAT GAATTCGTGA AAGGACAAAT TGTTATTCTT 
GAAGAGACTA TAAATGTCCA TGAGATGGAA GCAAAAGCTA GCAGAGAAAC GATCATGAGG 
CTGGCTTCAG AAGTCAACAG AGAGCAGAAA AAAGCTGCCT CCTGTACTGA AGAGAAAGAG 
AAGCTGAACC AGGACCTGCT CAGTGCTGTA GAAGCAAAAG AAGCTCTTGA AAGGGAAGTT 
AAGATCTTCC AAGAAAGGCT GCTTGCTGGC CAGCAGGTCT GGGATGCCTC AAAGCAGGAA 
GTGAGCCTCC TGAAGAAAAG CTCTTCTGAG TTGGAGAAGA GTTTGAAGGC CAGTCAGGAT 
GCAGTCACAA CCTCACAAAG CCAGTACTTC TCATTTAGGG AGAAAATCGC AGCCCTCCTT 
AGGGGCAGAT TGAGCATGAC TGGGTCCACT GAGGACACCA TTTTGGAGAA GATTCGAGAA 
ATGGACAGCC GGGAAGAAAG CAGGGACCGG TATCTTAAAT TTCTGGATCA GCTTTCTCAG 
AAAATGAAGT TGGACCAGAT GGCTGCCGAA CTTGGCTTTG ACATGCGGCT GGACGTGGTT 
TTAGCTCGAA CAGAGCAGCT GGTTCGTCTT GAGAGCAATG CAGTCATTGA GAACAAGACC 
ATTGCCCACA ATTTGCAGAG AAAGCTAAAG ACACAGAAAG AGAGACTGGA GAGCAAAGAA 
TTACACATGA GCCTCCTCCG GCAGAAAATA GCCCAGCTGG AGGAGGAGAA GCAGGCACGC 
ACGGCCTTGG TGGTTGAGAG GGACAACGCG CATCTTACCA TCAGGAACTT GCAGAAGAAG 
GTGGAGAGGC TGCAGAAAGA GCTGAACACG TGTCGAGACT TGCACACCGA GCTCAAAGCC 
AAACTGGCCG ACACCAATGA ACTGAAGATT AAAACTTTGG AACAGACTAA AGCCATTGAA 
GATCTAAACA AATCCAGAGA CCAACTGGAG AAGATGAAGG AGAAAGCTGA GAAAAAGCTC 
ATGTCTGTCA AGTCAGAACT GGATACCACA GAACATGAGG CTAAGGAGAA TAAAGAAAGG 
GCCAGAAACA TGATAGAAGT GGTAACCAGT GAAATGAAGA CACTAAAAAA ATCTCTGGAA 
GAAGCAGAAA AGAGAGAAAA GCAGCTGGCA GACTTCAGGG AGGTGGTGTC GCAGATGCTA 
GGCTTGAACG TGACCAGCCT TGCTCTTCCT GATTATGAAA TCATCAAGTG TCTTGAAAGA 
TTGGTCCATT CACATCAGCA TCACTTTGTT ACCTGTGCCT GCCTCAAAGA TGTGACTACT 
GGGCAAGAGA GGCACCCACA AGGCCATTTA CAGCTTCTTC ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCDC170 ( XM_011536147.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534449.1 Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu72575
Clone ID Related Accession (Same CDS sequence)	XM_011536147.2
Accession Version	XM_011536147.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	coiled-coil domain-containing protein 170 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536147.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTCAGA TGGAAACAGG ACCAGAGGGT TCAGTCTGCA GCCCACAGGC CAAACCCACC 
AAATCTGCTC TGCAGGAAAC TTACGATCAT CTTTCGGAAG TCCCGGTCAC GCGGGAGCAG 
TTAAACCACT ATCGGAATGT GGCTCAAAAT GCTCGAAGTG AACTTGCAGC AACTTTGGTC 
AAATTTGAAT GTGCTCAGTC TGAGCTTCAA GACCTCCGAT CCAAGATGCT TTCTAAAGAA 
GTCTCCTGTC AAGAACTGAA AGCTGAAATG GAGAGCTACA AGGAAAACAA TGCCAGAAAA 
TCATCTCTCC TTACCTCTTT GAGAGACAGA GTTCAGGAAC TAGAAGAAGA ATCAGCAGCA 
CTTTCCACTT CTAAAATCAG AACAGAAATC ACAGCTCACG CTGCAATCAA GGAGAACCAG 
GAATTAAAGA AGAAAGTTGT AGAGTTAAAT GAAAAATTAC AAAAGTGTTC AAAAGAAAAT 
GAGGAGAATA AGAAACAAGT TTCAAAGAAT TGCAGGAAAC ATGAGGAATT TCTGACTCAA 
CTGCGTGACT GCTTGGATCC AGATGAGAGG AATGACAAGG CATCAGATGA AGATTTAATT 
TTAAAGCTTA GAGACCTGCG CAAAGAAAAT GAATTCGTGA AAGGACAAAT TGTTATTCTT 
GAAGAGACTA TAAATGTCCA TGAGATGGAA GCAAAAGCTA GCAGAGAAAC GATCATGAGG 
CTGGCTTCAG AAGTCAACAG AGAGCAGAAA AAAGCTGCCT CCTGTACTGA AGAGAAAGAG 
AAGCTGAACC AGGACCTGCT CAGTGCTGTA GAAGCAAAAG AAGCTCTTGA AAGGGAAGTT 
AAGATCTTCC AAGAAAGGCT GCTTGCTGGC CAGCAGGTCT GGGATGCCTC AAAGCAGGAA 
GTGAGCCTCC TGAAGAAAAG CTCTTCTGAG TTGGAGAAGA GTTTGAAGGC CAGTCAGGAT 
GCAGTCACAA CCTCACAAAG CCAGTACTTC TCATTTAGGG AGAAAATCGC AGCCCTCCTT 
AGGGGCAGAT TGAGCATGAC TGGGTCCACT GAGGACACCA TTTTGGAGAA GATTCGAGAA 
ATGGACAGCC GGGAAGAAAG CAGGGACCGG ATGGTCTCCC AGCTTGAAGC CCAAATATCT 
GAGCTTGTTG AACAGTTGGG AAAGGAGTCT GGGTTTCACC AGAAAGCTCT CCAGAGGGCC 
CAGAAAGCAG AGAATATGTT GGAGACTCTT CAGGGTCAGC TGACACACCT GGAGGCAGAG 
CTGGTTTCTG GAGGTGTTTT GCGAGACAAC TTGAATTTTG AGAAACAAAA ATATCTTAAA 
TTTCTGGATC AGCTTTCTCA GAAAATGAAG TTGGACCAGA TGGCTGCCGA ACTTGGCTTT 
GACATGCGGC TGGACGTGGT TTTAGCTCGA ACAGAGCAGC TGGTTCGTCT TGAGAGCAAT 
GCAGTCATTG AGAACAAGAC CATTGCCCAC AATTTGCAGA GAAAGCTAAA GACACAGAAA 
GAGAGACTGG AGAGCAAAGA ATTACACATG AGCCTCCTCC GGCAGAAAAT AGCCCAGCTG 
GAGGAGGAGA AGCAGGCACG CACGGCCTTG GTGGTTGAGA GGGACAACGC GCATCTTACC 
ATCAGGAACT TGCAGAAGAA GGTGGAGAGG CTGCAGAAAG AGCTGAACAC GTGTCGAGAC 
TTGCACACCG AGCTCAAAGC CAAACTGGCC GACACCAATG AACTGAAGAT TAAAACTTTG 
GAACAGACTA AAGCCATTGA AGATCTAAAC AAATCCAGAG ACCAACTGGA GAAGATGAAG 
GAGAAAGCTG AGAAAAAGCT CATGTCTGTC AAGTCAGAAC TGGATACCAC AGAACATGAG 
GCTAAGGAGA ATAAAGAAAG GGCCAGAAAC ATGATAGAAG TGGTAACCAG TGAAATGAAG 
ACACTAAAAA AATCTCTGGA AGAAGCAGAA AAGAGAGAAA AGCAGCTGGC AGACTTCAGG 
GAGGTGGTGT CGCAGATGCT AGGCTTGAAC GTGACCAGCC TTGCTCTTCC TGATTATGAA 
ATCATCAAGT GTCTTGAAAG ATTGGTCCAT TCACATCAGC ATCACTTTGT TACCTGTGCC 
TGCCTCAAAG ATGTGACTAC TGGGCAAGAG AGGCACCCAC AAGGCCATTT ACAGCTTCTT 
CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534449.1
CDS	110..2275
Translation	MSQMETGPEGSVCSPQAKPTKSALQETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH

Target ORF information:

RefSeq Version	XM_011536147.2
Organism	Homo sapiens(human)
Definition	Homo sapiens coiled-coil domain containing 170 (CCDC170), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011536147.2

ORF Insert Sequence:

ATGAGTCAGA TGGAAACAGG ACCAGAGGGT TCAGTCTGCA GCCCACAGGC CAAACCCACC 
AAATCTGCTC TGCAGGAAAC TTACGATCAT CTTTCGGAAG TCCCGGTCAC GCGGGAGCAG 
TTAAACCACT ATCGGAATGT GGCTCAAAAT GCTCGAAGTG AACTTGCAGC AACTTTGGTC 
AAATTTGAAT GTGCTCAGTC TGAGCTTCAA GACCTCCGAT CCAAGATGCT TTCTAAAGAA 
GTCTCCTGTC AAGAACTGAA AGCTGAAATG GAGAGCTACA AGGAAAACAA TGCCAGAAAA 
TCATCTCTCC TTACCTCTTT GAGAGACAGA GTTCAGGAAC TAGAAGAAGA ATCAGCAGCA 
CTTTCCACTT CTAAAATCAG AACAGAAATC ACAGCTCACG CTGCAATCAA GGAGAACCAG 
GAATTAAAGA AGAAAGTTGT AGAGTTAAAT GAAAAATTAC AAAAGTGTTC AAAAGAAAAT 
GAGGAGAATA AGAAACAAGT TTCAAAGAAT TGCAGGAAAC ATGAGGAATT TCTGACTCAA 
CTGCGTGACT GCTTGGATCC AGATGAGAGG AATGACAAGG CATCAGATGA AGATTTAATT 
TTAAAGCTTA GAGACCTGCG CAAAGAAAAT GAATTCGTGA AAGGACAAAT TGTTATTCTT 
GAAGAGACTA TAAATGTCCA TGAGATGGAA GCAAAAGCTA GCAGAGAAAC GATCATGAGG 
CTGGCTTCAG AAGTCAACAG AGAGCAGAAA AAAGCTGCCT CCTGTACTGA AGAGAAAGAG 
AAGCTGAACC AGGACCTGCT CAGTGCTGTA GAAGCAAAAG AAGCTCTTGA AAGGGAAGTT 
AAGATCTTCC AAGAAAGGCT GCTTGCTGGC CAGCAGGTCT GGGATGCCTC AAAGCAGGAA 
GTGAGCCTCC TGAAGAAAAG CTCTTCTGAG TTGGAGAAGA GTTTGAAGGC CAGTCAGGAT 
GCAGTCACAA CCTCACAAAG CCAGTACTTC TCATTTAGGG AGAAAATCGC AGCCCTCCTT 
AGGGGCAGAT TGAGCATGAC TGGGTCCACT GAGGACACCA TTTTGGAGAA GATTCGAGAA 
ATGGACAGCC GGGAAGAAAG CAGGGACCGG ATGGTCTCCC AGCTTGAAGC CCAAATATCT 
GAGCTTGTTG AACAGTTGGG AAAGGAGTCT GGGTTTCACC AGAAAGCTCT CCAGAGGGCC 
CAGAAAGCAG AGAATATGTT GGAGACTCTT CAGGGTCAGC TGACACACCT GGAGGCAGAG 
CTGGTTTCTG GAGGTGTTTT GCGAGACAAC TTGAATTTTG AGAAACAAAA ATATCTTAAA 
TTTCTGGATC AGCTTTCTCA GAAAATGAAG TTGGACCAGA TGGCTGCCGA ACTTGGCTTT 
GACATGCGGC TGGACGTGGT TTTAGCTCGA ACAGAGCAGC TGGTTCGTCT TGAGAGCAAT 
GCAGTCATTG AGAACAAGAC CATTGCCCAC AATTTGCAGA GAAAGCTAAA GACACAGAAA 
GAGAGACTGG AGAGCAAAGA ATTACACATG AGCCTCCTCC GGCAGAAAAT AGCCCAGCTG 
GAGGAGGAGA AGCAGGCACG CACGGCCTTG GTGGTTGAGA GGGACAACGC GCATCTTACC 
ATCAGGAACT TGCAGAAGAA GGTGGAGAGG CTGCAGAAAG AGCTGAACAC GTGTCGAGAC 
TTGCACACCG AGCTCAAAGC CAAACTGGCC GACACCAATG AACTGAAGAT TAAAACTTTG 
GAACAGACTA AAGCCATTGA AGATCTAAAC AAATCCAGAG ACCAACTGGA GAAGATGAAG 
GAGAAAGCTG AGAAAAAGCT CATGTCTGTC AAGTCAGAAC TGGATACCAC AGAACATGAG 
GCTAAGGAGA ATAAAGAAAG GGCCAGAAAC ATGATAGAAG TGGTAACCAG TGAAATGAAG 
ACACTAAAAA AATCTCTGGA AGAAGCAGAA AAGAGAGAAA AGCAGCTGGC AGACTTCAGG 
GAGGTGGTGT CGCAGATGCT AGGCTTGAAC GTGACCAGCC TTGCTCTTCC TGATTATGAA 
ATCATCAAGT GTCTTGAAAG ATTGGTCCAT TCACATCAGC ATCACTTTGT TACCTGTGCC 
TGCCTCAAAG ATGTGACTAC TGGGCAAGAG AGGCACCCAC AAGGCCATTT ACAGCTTCTT 
CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network.
EBioMedicine2228-43(2017 Aug)
Jiang P,Li Y,Poleshko A,Medvedeva V,Baulina N,Zhang Y,Zhou Y,Slater CM,Pellegrin T,Wasserman J,Lindy M,Efimov A,Daly M,Katz RA,Chen X

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Nature genetics48(4)374-86(2016 Apr)
Dunning AM,Michailidou K,Kuchenbaecker KB,Thompson D,French JD,Beesley J,Healey CS,Kar S,Pooley KA,Lopez-Knowles E,Dicks E,Barrowdale D,Sinnott-Armstrong NA,Sallari RC,Hillman KM,Kaufmann S,Sivakumaran H,Moradi Marjaneh M,Lee JS,Hills M,Jarosz M,Drury S,Canisius S,Bolla MK,Dennis J,Wang Q,Hopper JL,Southey MC,Broeks A,Schmidt MK,Lophatananon A,Muir K,Beckmann MW,Fasching PA,Dos-Santos-Silva I,Peto J,Sawyer EJ,Tomlinson I,Burwinkel B,Marme F,Gu?nel P,Truong T,Bojesen SE,Flyger H,Gonz?lez-Neira A,Perez JI,Anton-Culver H,Eunjung L,Arndt V,Brenner H,Meindl A,Schmutzler RK,Brauch H,Hamann U,Aittom?ki K,Blomqvist C,Ito H,Matsuo K,Bogdanova N,D?rk T,Lindblom A,Margolin S,Kosma VM,Mannermaa A,Tseng CC,Wu AH,Lambrechts D,Wildiers H,Chang-Claude J,Rudolph A,Peterlongo P,Radice P,Olson JE,Giles GG,Milne RL,Haiman CA,Henderson BE,Goldberg MS,Teo SH,Yip CH,Nord S,Borresen-Dale AL,Kristensen V,Long J,Zheng W,Pylk?s K,Winqvist R,Andrulis IL,Knight JA,Devilee P,Seynaeve C,Figueroa J,Sherman ME,Czene K,Darabi H,Hollestelle A,van den Ouweland AM,Humphreys K,Gao YT,Shu XO,Cox A,Cross SS,Blot W,Cai Q,Ghoussaini M,Perkins BJ,Shah M,Choi JY,Kang D,Lee SC,Hartman M,Kabisch M,Torres D,Jakubowska A,Lubinski J,Brennan P,Sangrajrang S,Ambrosone CB,Toland AE,Shen CY,Wu PE,Orr N,Swerdlow A,McGuffog L,Healey S,Lee A,Kapuscinski M,John EM,Terry MB,Daly MB,Goldgar DE,Buys SS,Janavicius R,Tihomirova L,Tung N,Dorfling CM,van Rensburg EJ,Neuhausen SL,Ejlertsen B,Hansen TV,Osorio A,Benitez J,Rando R,Weitzel JN,Bonanni B,Peissel B,Manoukian S,Papi L,Ottini L,Konstantopoulou I,Apostolou P,Garber J,Rashid MU,Frost D,,Izatt L,Ellis S,Godwin AK,Arnold N,Niederacher D,Rhiem K,Bogdanova-Markov N,Sagne C,Stoppa-Lyonnet D,Damiola F,,Sinilnikova OM,Mazoyer S,Isaacs C,Claes KB,De Leeneer K,de la Hoya M,Caldes T,Nevanlinna H,Khan S,Mensenkamp AR,,Hooning MJ,Rookus MA,Kwong A,Olah E,Diez O,Brunet J,Pujana MA,Gronwald J,Huzarski T,Barkardottir RB,Laframboise R,Soucy P,Montagna M,Agata S,Teixeira MR,,Park SK,Lindor N,Couch FJ,Tischkowitz M,Foretova L,Vijai J,Offit K,Singer CF,Rappaport C,Phelan CM,Greene MH,Mai PL,Rennert G,Imyanitov EN,Hulick PJ,Phillips KA,Piedmonte M,Mulligan AM,Glendon G,Bojesen A,Thomassen M,Caligo MA,Yoon SY,Friedman E,Laitman Y,Borg A,von Wachenfeldt A,Ehrencrona H,Rantala J,Olopade OI,Ganz PA,Nussbaum RL,Gayther SA,Nathanson KL,Domchek SM,Arun BK,Mitchell G,Karlan BY,Lester J,Maskarinec G,Woolcott C,Scott C,Stone J,Apicella C,Tamimi R,Luben R,Khaw KT,Helland ?,Haakensen V,Dowsett M,Pharoah PD,Simard J,Hall P,Garc?a-Closas M,Vachon C,Chenevix-Trench G,Antoniou AC,Easton DF,Edwards SL

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.
BMC genomics17136(2016 Feb)
Mullin BH,Walsh JP,Zheng HF,Brown SJ,Surdulescu GL,Curtis C,Breen G,Dudbridge F,Richards JB,Spector TD,Wilson SG

C6ORF97-ESR1 breast cancer susceptibility locus: influence on progression and survival in breast cancer patients.
European journal of human genetics : EJHG23(7)949-56(2015 Jul)
Yamamoto-Ibusuki M,Yamamoto Y,Fujiwara S,Sueta A,Yamamoto S,Hayashi M,Tomiguchi M,Takeshita T,Iwase H

Current evidence on the association between rs3757318 of C6orf97 and breast cancer risk: a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP15(19)8051-5(2014)
Hong Y,Chen XQ,Li JY,Liu C,Shen N,Zhu BB,Gong J,Chen W

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CCDC170 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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