COQ8B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	COQ8B
Entrez Gene ID	79934
Full Name	coenzyme Q8B
Synonyms	ADCK4,NPHS9
General protein information	Preferred Names coenzyme Q8B Names atypical kinase COQ8B, mitochondrial aarF domain containing kinase 4 aarF domain-containing protein kinase 4 coenzyme Q protein 8B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	This gene encodes a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and binding sites of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Disorder MIM:	615567
Disorder Html:	Nephrotic syndrome, type 9, 615573 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001142555.3	NP_001136027.1	atypical kinase COQ8B, mitochondrial isoform b
NM_024876.3	NP_079152.3	atypical kinase COQ8B, mitochondrial isoform a
NM_001142555.2	NP_001136027.1	atypical kinase COQ8B, mitochondrial isoform b
NM_024876.4	NP_079152.3	atypical kinase COQ8B, mitochondrial isoform a

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002906	XP_311995.4
Homo sapiens (human)	ADCK4	NP_079152.3
	ADCK4	XP_001097315.1
Canis lupus familiaris (dog)	ADCK4	XP_541612.3
Bos taurus (cattle)	ADCK4	XP_002695038.2
Arabidopsis thaliana (thale cress)	ABC1	NP_192075.1
Drosophila melanogaster (fruit fly)	CG32649	NP_572836.1
Oryza sativa (rice)	Os01g0318700	NP_001042885.1
Pan troglodytes (chimpanzee)	ADCK4	XP_512672.3
Mus musculus (house mouse)	Adck4	NP_598531.2
Rattus norvegicus (Norway rat)	Adck4	NP_001012065.1
Xenopus tropicalis (tropical clawed frog)	adck4	XP_002938863.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in COQ8B (ADCK4) found in patients with steroid-resistant nephrotic syndrome alter COQ8B function.
Vazquez Fonseca L, Doimo M, Calderan C, Desbats MA, Acosta MJ, Cerqua C, Cassina M, Ashraf S, Hildebrandt F, Sartori G, Navas P, Trevisson E, Salviati L
Human mutation(2017 Dec)

Focal segmental glomerulosclerosis and medullary nephrocalcinosis in children with ADCK4 mutations.
Park E, Kang HG, Choi YH, Lee KB, Moon KC, Jeong HJ, Nagata M, Cheong HI
Pediatric nephrology (Berlin, Germany)(2017 Apr)

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
Stefely JA, Licitra F, Laredj L, Reidenbach AG, Kemmerer ZA, Grangeray A, Jaeg-Ehret T, Minogue CE, Ulbrich A, Hutchins PD, Wilkerson EM, Ruan Z, Aydin D, Hebert AS, Guo X, Freiberger EC, Reutenauer L, Jochem A, Chergova M, Johnson IE, Lohman DC, Rush MJP, Kwiecien NW, Singh PK, Schlagowski AI, Floyd BJ, Forsman U, Sindelar PJ, Westphall MS, Pierrel F, Zoll J, Dal Peraro M, Kannan N, Bingman CA, Coon JJ, Isope P, Puccio H, Pagliarini DJ
Molecular cell63(4)608-620(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mutations in ADCK4 resulted in reduced CoQ10 levels and reduced mitochondrial respiratory enzyme activity in cells isolated from individuals with steroid-resistant nephrotic syndrome & transformed lymphoblasts.
Title: ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following COQ8B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COQ8B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19203	NM_024876.4 Latest version!	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu08854	NM_001142555.3 Latest version!	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu08854	NM_001142555.2	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu19203	NM_024876.3	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COQ8B ( NM_024876.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079152.3 Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19203
Clone ID Related Accession (Same CDS sequence)	NM_024876.3 , NM_024876.4
Accession Version	NM_024876.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1635bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	atypical kinase COQ8B, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU121879.1, BC013114.1 and BC013884.1. This sequence is a reference standard in the RefSeqGene project. On Dec 13, 2008 this sequence version replaced NM_024876.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: BC013114.1, SRR1803612.1340.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGAGG GTGGTTCTGG GCTGGACTCC AGCCCCTTCC TGTCGGAGGC CAATGCCGAG 
CGGATTGTGC AGACCTTATG TACAGTTCGA GGGGCCGCCC TCAAGGTTGG CCAGATGCTC 
AGCATCCAGG ACAACAGCTT CATCAGCCCT CAGCTGCAGC ACATCTTTGA GCGGGTCCGC 
CAGAGCGCCG ACTTCATGCC CCGCTGGCAG ATGCTGAGAG TTCTTGAAGA GGAGCTCGGC 
AGGGACTGGC AGGCCAAGGT GGCCTCCTTG GAGGAGGTGC CCTTTGCCGC TGCCTCAATT 
GGGCAGGTGC ACCAGGGCCT GCTGAGGGAC GGGACGGAGG TGGCCGTGAA GATCCAGTAC 
CCCGGCATAG CCCAGAGCAT TCAGAGCGAT GTCCAGAACC TGCTGGCGGT ACTCAAGATG 
AGCGCGGCCC TGCCCGCGGG CCTGTTTGCC GAGCAGAGCC TGCAGGCCTT GCAGCAGGAG 
CTGGCTTGGG AGTGTGACTA CCGTCGTGAG GCGGCTTGTG CCCAGAATTT CAGGCAGCTG 
CTGGCAAATG ACCCCTTCTT CCGGGTCCCA GCCGTGGTTA AGGAGCTGTG CACGACACGG 
GTGCTGGGCA TGGAGCTGGC TGGAGGGGTC CCCCTGGACC AGTGCCAGGG CCTAAGCCAG 
GACCTGCGGA ACCAGATTTG CTTCCAGCTC CTGACGCTGT GTCTGCGGGA GCTGTTTGAG 
TTCCGATTCA TGCAGACTGA CCCCAACTGG GCCAACTTCC TGTATGATGC CTCCAGCCAC 
CAGGTGACCC TGCTGGACTT TGGTGCAAGC CGGGAGTTTG GGACAGAGTT CACAGACCAT 
TACATCGAGG TGGTGAAGGC TGCAGCTGAT GGAGACAGAG ACTGTGTCCT GCAGAAGTCC 
AGGGACCTCA AATTCCTCAC AGGCTTTGAA ACCAAGGCAT TCTCCGACGC CCACGTGGAG 
GCAGTGATGA TCCTGGGGGA GCCTTTCGCC ACCCAGGGCC CTTATGACTT TGGGTCGGGG 
GAAACGGCCC GCCGCATACA GGACCTCATC CCGGTGCTGC TGCGGCACCG GCTGTGTCCC 
CCACCCGAGG AGACCTATGC CCTGCACCGC AAGCTGGCAG GGGCTTTCCT GGCCTGTGCC 
CACCTCCGAG CCCACATCGC CTGCAGGGAC CTCTTCCAGG ACACCTACCA CCGCTACTGG 
GCCAGTCGCC AGCCAGACGC AGCCACTGCC GGCAGCCTCC CCACCAAAGG GGACTCCTGG 
GTGGATCCCT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079152.3
CDS	303..1937
Translation	MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS

Target ORF information:

RefSeq Version	NM_024876.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024876.3

ORF Insert Sequence:

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGAGG GTGGTTCTGG GCTGGACTCC AGCCCCTTCC TGTCGGAGGC CAATGCCGAG 
CGGATTGTGC AGACCTTATG TACAGTTCGA GGGGCCGCCC TCAAGGTTGG CCAGATGCTC 
AGCATCCAGG ACAACAGCTT CATCAGCCCT CAGCTGCAGC ACATCTTTGA GCGGGTCCGC 
CAGAGCGCCG ACTTCATGCC CCGCTGGCAG ATGCTGAGAG TTCTTGAAGA GGAGCTCGGC 
AGGGACTGGC AGGCCAAGGT GGCCTCCTTG GAGGAGGTGC CCTTTGCCGC TGCCTCAATT 
GGGCAGGTGC ACCAGGGCCT GCTGAGGGAC GGGACGGAGG TGGCCGTGAA GATCCAGTAC 
CCCGGCATAG CCCAGAGCAT TCAGAGCGAT GTCCAGAACC TGCTGGCGGT ACTCAAGATG 
AGCGCGGCCC TGCCCGCGGG CCTGTTTGCC GAGCAGAGCC TGCAGGCCTT GCAGCAGGAG 
CTGGCTTGGG AGTGTGACTA CCGTCGTGAG GCGGCTTGTG CCCAGAATTT CAGGCAGCTG 
CTGGCAAATG ACCCCTTCTT CCGGGTCCCA GCCGTGGTTA AGGAGCTGTG CACGACACGG 
GTGCTGGGCA TGGAGCTGGC TGGAGGGGTC CCCCTGGACC AGTGCCAGGG CCTAAGCCAG 
GACCTGCGGA ACCAGATTTG CTTCCAGCTC CTGACGCTGT GTCTGCGGGA GCTGTTTGAG 
TTCCGATTCA TGCAGACTGA CCCCAACTGG GCCAACTTCC TGTATGATGC CTCCAGCCAC 
CAGGTGACCC TGCTGGACTT TGGTGCAAGC CGGGAGTTTG GGACAGAGTT CACAGACCAT 
TACATCGAGG TGGTGAAGGC TGCAGCTGAT GGAGACAGAG ACTGTGTCCT GCAGAAGTCC 
AGGGACCTCA AATTCCTCAC AGGCTTTGAA ACCAAGGCAT TCTCCGACGC CCACGTGGAG 
GCAGTGATGA TCCTGGGGGA GCCTTTCGCC ACCCAGGGCC CTTATGACTT TGGGTCGGGG 
GAAACGGCCC GCCGCATACA GGACCTCATC CCGGTGCTGC TGCGGCACCG GCTGTGTCCC 
CCACCCGAGG AGACCTATGC CCTGCACCGC AAGCTGGCAG GGGCTTTCCT GGCCTGTGCC 
CACCTCCGAG CCCACATCGC CTGCAGGGAC CTCTTCCAGG ACACCTACCA CCGCTACTGG 
GCCAGTCGCC AGCCAGACGC AGCCACTGCC GGCAGCCTCC CCACCAAAGG GGACTCCTGG 
GTGGATCCCT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COQ8B ( NM_024876.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_079152.3 Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19203
Clone ID Related Accession (Same CDS sequence)	NM_024876.3 , NM_024876.4
Accession Version	NM_024876.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1635bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	atypical kinase COQ8B, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC010412.9, AU121879.1, BC013114.1 and BC013884.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_024876.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1803612.1340.1, SRR1660803.29598.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000324464.8/ ENSP00000315118.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGAGG GTGGTTCTGG GCTGGACTCC AGCCCCTTCC TGTCGGAGGC CAATGCCGAG 
CGGATTGTGC AGACCTTATG TACAGTTCGA GGGGCCGCCC TCAAGGTTGG CCAGATGCTC 
AGCATCCAGG ACAACAGCTT CATCAGCCCT CAGCTGCAGC ACATCTTTGA GCGGGTCCGC 
CAGAGCGCCG ACTTCATGCC CCGCTGGCAG ATGCTGAGAG TTCTTGAAGA GGAGCTCGGC 
AGGGACTGGC AGGCCAAGGT GGCCTCCTTG GAGGAGGTGC CCTTTGCCGC TGCCTCAATT 
GGGCAGGTGC ACCAGGGCCT GCTGAGGGAC GGGACGGAGG TGGCCGTGAA GATCCAGTAC 
CCCGGCATAG CCCAGAGCAT TCAGAGCGAT GTCCAGAACC TGCTGGCGGT ACTCAAGATG 
AGCGCGGCCC TGCCCGCGGG CCTGTTTGCC GAGCAGAGCC TGCAGGCCTT GCAGCAGGAG 
CTGGCTTGGG AGTGTGACTA CCGTCGTGAG GCGGCTTGTG CCCAGAATTT CAGGCAGCTG 
CTGGCAAATG ACCCCTTCTT CCGGGTCCCA GCCGTGGTTA AGGAGCTGTG CACGACACGG 
GTGCTGGGCA TGGAGCTGGC TGGAGGGGTC CCCCTGGACC AGTGCCAGGG CCTAAGCCAG 
GACCTGCGGA ACCAGATTTG CTTCCAGCTC CTGACGCTGT GTCTGCGGGA GCTGTTTGAG 
TTCCGATTCA TGCAGACTGA CCCCAACTGG GCCAACTTCC TGTATGATGC CTCCAGCCAC 
CAGGTGACCC TGCTGGACTT TGGTGCAAGC CGGGAGTTTG GGACAGAGTT CACAGACCAT 
TACATCGAGG TGGTGAAGGC TGCAGCTGAT GGAGACAGAG ACTGTGTCCT GCAGAAGTCC 
AGGGACCTCA AATTCCTCAC AGGCTTTGAA ACCAAGGCAT TCTCCGACGC CCACGTGGAG 
GCAGTGATGA TCCTGGGGGA GCCTTTCGCC ACCCAGGGCC CTTATGACTT TGGGTCGGGG 
GAAACGGCCC GCCGCATACA GGACCTCATC CCGGTGCTGC TGCGGCACCG GCTGTGTCCC 
CCACCCGAGG AGACCTATGC CCTGCACCGC AAGCTGGCAG GGGCTTTCCT GGCCTGTGCC 
CACCTCCGAG CCCACATCGC CTGCAGGGAC CTCTTCCAGG ACACCTACCA CCGCTACTGG 
GCCAGTCGCC AGCCAGACGC AGCCACTGCC GGCAGCCTCC CCACCAAAGG GGACTCCTGG 
GTGGATCCCT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079152.3
CDS	304..1938
Translation	MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS

Target ORF information:

RefSeq Version	NM_024876.4
Organism	Homo sapiens(human)
Definition	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024876.4

ORF Insert Sequence:

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGAGG GTGGTTCTGG GCTGGACTCC AGCCCCTTCC TGTCGGAGGC CAATGCCGAG 
CGGATTGTGC AGACCTTATG TACAGTTCGA GGGGCCGCCC TCAAGGTTGG CCAGATGCTC 
AGCATCCAGG ACAACAGCTT CATCAGCCCT CAGCTGCAGC ACATCTTTGA GCGGGTCCGC 
CAGAGCGCCG ACTTCATGCC CCGCTGGCAG ATGCTGAGAG TTCTTGAAGA GGAGCTCGGC 
AGGGACTGGC AGGCCAAGGT GGCCTCCTTG GAGGAGGTGC CCTTTGCCGC TGCCTCAATT 
GGGCAGGTGC ACCAGGGCCT GCTGAGGGAC GGGACGGAGG TGGCCGTGAA GATCCAGTAC 
CCCGGCATAG CCCAGAGCAT TCAGAGCGAT GTCCAGAACC TGCTGGCGGT ACTCAAGATG 
AGCGCGGCCC TGCCCGCGGG CCTGTTTGCC GAGCAGAGCC TGCAGGCCTT GCAGCAGGAG 
CTGGCTTGGG AGTGTGACTA CCGTCGTGAG GCGGCTTGTG CCCAGAATTT CAGGCAGCTG 
CTGGCAAATG ACCCCTTCTT CCGGGTCCCA GCCGTGGTTA AGGAGCTGTG CACGACACGG 
GTGCTGGGCA TGGAGCTGGC TGGAGGGGTC CCCCTGGACC AGTGCCAGGG CCTAAGCCAG 
GACCTGCGGA ACCAGATTTG CTTCCAGCTC CTGACGCTGT GTCTGCGGGA GCTGTTTGAG 
TTCCGATTCA TGCAGACTGA CCCCAACTGG GCCAACTTCC TGTATGATGC CTCCAGCCAC 
CAGGTGACCC TGCTGGACTT TGGTGCAAGC CGGGAGTTTG GGACAGAGTT CACAGACCAT 
TACATCGAGG TGGTGAAGGC TGCAGCTGAT GGAGACAGAG ACTGTGTCCT GCAGAAGTCC 
AGGGACCTCA AATTCCTCAC AGGCTTTGAA ACCAAGGCAT TCTCCGACGC CCACGTGGAG 
GCAGTGATGA TCCTGGGGGA GCCTTTCGCC ACCCAGGGCC CTTATGACTT TGGGTCGGGG 
GAAACGGCCC GCCGCATACA GGACCTCATC CCGGTGCTGC TGCGGCACCG GCTGTGTCCC 
CCACCCGAGG AGACCTATGC CCTGCACCGC AAGCTGGCAG GGGCTTTCCT GGCCTGTGCC 
CACCTCCGAG CCCACATCGC CTGCAGGGAC CTCTTCCAGG ACACCTACCA CCGCTACTGG 
GCCAGTCGCC AGCCAGACGC AGCCACTGCC GGCAGCCTCC CCACCAAAGG GGACTCCTGG 
GTGGATCCCT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COQ8B ( NM_001142555.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136027.1 Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08854
Clone ID Related Accession (Same CDS sequence)	NM_001142555.3 , NM_001142555.2
Accession Version	NM_001142555.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	atypical kinase COQ8B, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC010412.9, CA397752.1 and BC027473.1. On May 31, 2019 this sequence version replaced NM_001142555.2. Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The resulting isoform (b) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC027473.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGACA ACAGCTTCAT CAGCCCTCAG CTGCAGCACA TCTTTGAGCG GGTCCGCCAG 
AGCGCCGACT TCATGCCCCG CTGGCAGATG CTGAGAGTTC TTGAAGAGGA GCTCGGCAGG 
GACTGGCAGG CCAAGGTGGC CTCCTTGGAG GAGGTGCCCT TTGCCGCTGC CTCAATTGGG 
CAGGTGCACC AGGGCCTGCT GAGGGACGGG ACGGAGGTGG CCGTGAAGAT CCAGTACCCC 
GGCATAGCCC AGAGCATTCA GAGCGATGTC CAGAACCTGC TGGCGGTACT CAAGATGAGC 
GCGGCCCTGC CCGCGGGCCT GTTTGCCGAG CAGAGCCTGC AGGCCTTGCA GCAGGAGCTG 
GCTTGGGAGT GTGACTACCG TCGTGAGGCG GCTTGTGCCC AGAATTTCAG GCAGCTGCTG 
GCAAATGACC CCTTCTTCCG GGTCCCAGCC GTGGTTAAGG AGCTGTGCAC GACACGGGTG 
CTGGGCATGG AGCTGGCTGG AGGGGTCCCC CTGGACCAGT GCCAGGGCCT AAGCCAGGAC 
CTGCGGAACC AGATTTGCTT CCAGCTCCTG ACGCTGTGTC TGCGGGAGCT GTTTGAGTTC 
CGATTCATGC AGACTGACCC CAACTGGGCC AACTTCCTGT ATGATGCCTC CAGCCACCAG 
GTGACCCTGC TGGACTTTGG TGCAAGCCGG GAGTTTGGGA CAGAGTTCAC AGACCATTAC 
ATCGAGGTGG TGAAGGCTGC AGCTGATGGA GACAGAGACT GTGTCCTGCA GAAGTCCAGG 
GACCTCAAAT TCCTCACAGG CTTTGAAACC AAGGCATTCT CCGACGCCCA CGTGGAGGCA 
GTGATGATCC TGGGGGAGCC TTTCGCCACC CAGGGCCCTT ATGACTTTGG GTCGGGGGAA 
ACGGCCCGCC GCATACAGGA CCTCATCCCG GTGCTGCTGC GGCACCGGCT GTGTCCCCCA 
CCCGAGGAGA CCTATGCCCT GCACCGCAAG CTGGCAGGGG CTTTCCTGGC CTGTGCCCAC 
CTCCGAGCCC ACATCGCCTG CAGGGACCTC TTCCAGGACA CCTACCACCG CTACTGGGCC 
AGTCGCCAGC CAGACGCAGC CACTGCCGGC AGCCTCCCCA CCAAAGGGGA CTCCTGGGTG 
GATCCCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136027.1
CDS	71..1582
Translation	MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS

Target ORF information:

RefSeq Version	NM_001142555.3
Organism	Homo sapiens(human)
Definition	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142555.3

ORF Insert Sequence:

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGACA ACAGCTTCAT CAGCCCTCAG CTGCAGCACA TCTTTGAGCG GGTCCGCCAG 
AGCGCCGACT TCATGCCCCG CTGGCAGATG CTGAGAGTTC TTGAAGAGGA GCTCGGCAGG 
GACTGGCAGG CCAAGGTGGC CTCCTTGGAG GAGGTGCCCT TTGCCGCTGC CTCAATTGGG 
CAGGTGCACC AGGGCCTGCT GAGGGACGGG ACGGAGGTGG CCGTGAAGAT CCAGTACCCC 
GGCATAGCCC AGAGCATTCA GAGCGATGTC CAGAACCTGC TGGCGGTACT CAAGATGAGC 
GCGGCCCTGC CCGCGGGCCT GTTTGCCGAG CAGAGCCTGC AGGCCTTGCA GCAGGAGCTG 
GCTTGGGAGT GTGACTACCG TCGTGAGGCG GCTTGTGCCC AGAATTTCAG GCAGCTGCTG 
GCAAATGACC CCTTCTTCCG GGTCCCAGCC GTGGTTAAGG AGCTGTGCAC GACACGGGTG 
CTGGGCATGG AGCTGGCTGG AGGGGTCCCC CTGGACCAGT GCCAGGGCCT AAGCCAGGAC 
CTGCGGAACC AGATTTGCTT CCAGCTCCTG ACGCTGTGTC TGCGGGAGCT GTTTGAGTTC 
CGATTCATGC AGACTGACCC CAACTGGGCC AACTTCCTGT ATGATGCCTC CAGCCACCAG 
GTGACCCTGC TGGACTTTGG TGCAAGCCGG GAGTTTGGGA CAGAGTTCAC AGACCATTAC 
ATCGAGGTGG TGAAGGCTGC AGCTGATGGA GACAGAGACT GTGTCCTGCA GAAGTCCAGG 
GACCTCAAAT TCCTCACAGG CTTTGAAACC AAGGCATTCT CCGACGCCCA CGTGGAGGCA 
GTGATGATCC TGGGGGAGCC TTTCGCCACC CAGGGCCCTT ATGACTTTGG GTCGGGGGAA 
ACGGCCCGCC GCATACAGGA CCTCATCCCG GTGCTGCTGC GGCACCGGCT GTGTCCCCCA 
CCCGAGGAGA CCTATGCCCT GCACCGCAAG CTGGCAGGGG CTTTCCTGGC CTGTGCCCAC 
CTCCGAGCCC ACATCGCCTG CAGGGACCTC TTCCAGGACA CCTACCACCG CTACTGGGCC 
AGTCGCCAGC CAGACGCAGC CACTGCCGGC AGCCTCCCCA CCAAAGGGGA CTCCTGGGTG 
GATCCCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COQ8B ( NM_001142555.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136027.1 Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.

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CloneID	OHu08854
Clone ID Related Accession (Same CDS sequence)	NM_001142555.3 , NM_001142555.2
Accession Version	NM_001142555.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	atypical kinase COQ8B, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA397752.1, BC027473.1 and BC013114.1. On Oct 6, 2010 this sequence version replaced NM_001142555.1. Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The resulting isoform (b) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC027473.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGACA ACAGCTTCAT CAGCCCTCAG CTGCAGCACA TCTTTGAGCG GGTCCGCCAG 
AGCGCCGACT TCATGCCCCG CTGGCAGATG CTGAGAGTTC TTGAAGAGGA GCTCGGCAGG 
GACTGGCAGG CCAAGGTGGC CTCCTTGGAG GAGGTGCCCT TTGCCGCTGC CTCAATTGGG 
CAGGTGCACC AGGGCCTGCT GAGGGACGGG ACGGAGGTGG CCGTGAAGAT CCAGTACCCC 
GGCATAGCCC AGAGCATTCA GAGCGATGTC CAGAACCTGC TGGCGGTACT CAAGATGAGC 
GCGGCCCTGC CCGCGGGCCT GTTTGCCGAG CAGAGCCTGC AGGCCTTGCA GCAGGAGCTG 
GCTTGGGAGT GTGACTACCG TCGTGAGGCG GCTTGTGCCC AGAATTTCAG GCAGCTGCTG 
GCAAATGACC CCTTCTTCCG GGTCCCAGCC GTGGTTAAGG AGCTGTGCAC GACACGGGTG 
CTGGGCATGG AGCTGGCTGG AGGGGTCCCC CTGGACCAGT GCCAGGGCCT AAGCCAGGAC 
CTGCGGAACC AGATTTGCTT CCAGCTCCTG ACGCTGTGTC TGCGGGAGCT GTTTGAGTTC 
CGATTCATGC AGACTGACCC CAACTGGGCC AACTTCCTGT ATGATGCCTC CAGCCACCAG 
GTGACCCTGC TGGACTTTGG TGCAAGCCGG GAGTTTGGGA CAGAGTTCAC AGACCATTAC 
ATCGAGGTGG TGAAGGCTGC AGCTGATGGA GACAGAGACT GTGTCCTGCA GAAGTCCAGG 
GACCTCAAAT TCCTCACAGG CTTTGAAACC AAGGCATTCT CCGACGCCCA CGTGGAGGCA 
GTGATGATCC TGGGGGAGCC TTTCGCCACC CAGGGCCCTT ATGACTTTGG GTCGGGGGAA 
ACGGCCCGCC GCATACAGGA CCTCATCCCG GTGCTGCTGC GGCACCGGCT GTGTCCCCCA 
CCCGAGGAGA CCTATGCCCT GCACCGCAAG CTGGCAGGGG CTTTCCTGGC CTGTGCCCAC 
CTCCGAGCCC ACATCGCCTG CAGGGACCTC TTCCAGGACA CCTACCACCG CTACTGGGCC 
AGTCGCCAGC CAGACGCAGC CACTGCCGGC AGCCTCCCCA CCAAAGGGGA CTCCTGGGTG 
GATCCCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136027.1
CDS	58..1569
Translation	MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS

Target ORF information:

RefSeq Version	NM_001142555.2
Organism	Homo sapiens(human)
Definition	Homo sapiens coenzyme Q8B (COQ8B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142555.2

ORF Insert Sequence:

ATGTGGCTGA AGGTGGGGGG CCTACTTCGG GGGACCGGTG GACAGCTGGG CCAGACTGTT 
GGTTGGCCTT GTGGGGCCCT GGGGCCTGGG CCCCACCGCT GGGGACCATG TGGAGGTTCT 
TGGGCCCAAA AGTTTTACCA GGATGGGCCT GGGAGAGGCC TGGGTGAGGA GGACATTCGC 
AGGGCACGGG AGGCCCGTCC CAGGAAGACA CCCCGGCCCC AGCTGAGTGA CCGCTCTCGA 
GAACGCAAGG TGCCTGCCTC CCGCATCAGC CGCTTGGCCA ACTTTGGGGG ACTGGCTGTG 
GGCTTGGGGC TAGGAGTACT GGCCGAGATG GCTAAGAAGT CCATGCCAGG AGGTCGTCTG 
CAGTCAGACA ACAGCTTCAT CAGCCCTCAG CTGCAGCACA TCTTTGAGCG GGTCCGCCAG 
AGCGCCGACT TCATGCCCCG CTGGCAGATG CTGAGAGTTC TTGAAGAGGA GCTCGGCAGG 
GACTGGCAGG CCAAGGTGGC CTCCTTGGAG GAGGTGCCCT TTGCCGCTGC CTCAATTGGG 
CAGGTGCACC AGGGCCTGCT GAGGGACGGG ACGGAGGTGG CCGTGAAGAT CCAGTACCCC 
GGCATAGCCC AGAGCATTCA GAGCGATGTC CAGAACCTGC TGGCGGTACT CAAGATGAGC 
GCGGCCCTGC CCGCGGGCCT GTTTGCCGAG CAGAGCCTGC AGGCCTTGCA GCAGGAGCTG 
GCTTGGGAGT GTGACTACCG TCGTGAGGCG GCTTGTGCCC AGAATTTCAG GCAGCTGCTG 
GCAAATGACC CCTTCTTCCG GGTCCCAGCC GTGGTTAAGG AGCTGTGCAC GACACGGGTG 
CTGGGCATGG AGCTGGCTGG AGGGGTCCCC CTGGACCAGT GCCAGGGCCT AAGCCAGGAC 
CTGCGGAACC AGATTTGCTT CCAGCTCCTG ACGCTGTGTC TGCGGGAGCT GTTTGAGTTC 
CGATTCATGC AGACTGACCC CAACTGGGCC AACTTCCTGT ATGATGCCTC CAGCCACCAG 
GTGACCCTGC TGGACTTTGG TGCAAGCCGG GAGTTTGGGA CAGAGTTCAC AGACCATTAC 
ATCGAGGTGG TGAAGGCTGC AGCTGATGGA GACAGAGACT GTGTCCTGCA GAAGTCCAGG 
GACCTCAAAT TCCTCACAGG CTTTGAAACC AAGGCATTCT CCGACGCCCA CGTGGAGGCA 
GTGATGATCC TGGGGGAGCC TTTCGCCACC CAGGGCCCTT ATGACTTTGG GTCGGGGGAA 
ACGGCCCGCC GCATACAGGA CCTCATCCCG GTGCTGCTGC GGCACCGGCT GTGTCCCCCA 
CCCGAGGAGA CCTATGCCCT GCACCGCAAG CTGGCAGGGG CTTTCCTGGC CTGTGCCCAC 
CTCCGAGCCC ACATCGCCTG CAGGGACCTC TTCCAGGACA CCTACCACCG CTACTGGGCC 
AGTCGCCAGC CAGACGCAGC CACTGCCGGC AGCCTCCCCA CCAAAGGGGA CTCCTGGGTG 
GATCCCTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in COQ8B (ADCK4) found in patients with steroid-resistant nephrotic syndrome alter COQ8B function.
Human mutation(2017 Dec)
Vazquez Fonseca L,Doimo M,Calderan C,Desbats MA,Acosta MJ,Cerqua C,Cassina M,Ashraf S,Hildebrandt F,Sartori G,Navas P,Trevisson E,Salviati L

Focal segmental glomerulosclerosis and medullary nephrocalcinosis in children with ADCK4 mutations.
Pediatric nephrology (Berlin, Germany)(2017 Apr)
Park E,Kang HG,Choi YH,Lee KB,Moon KC,Jeong HJ,Nagata M,Cheong HI

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
Molecular cell63(4)608-620(2016 Aug)
Stefely JA,Licitra F,Laredj L,Reidenbach AG,Kemmerer ZA,Grangeray A,Jaeg-Ehret T,Minogue CE,Ulbrich A,Hutchins PD,Wilkerson EM,Ruan Z,Aydin D,Hebert AS,Guo X,Freiberger EC,Reutenauer L,Jochem A,Chergova M,Johnson IE,Lohman DC,Rush MJP,Kwiecien NW,Singh PK,Schlagowski AI,Floyd BJ,Forsman U,Sindelar PJ,Westphall MS,Pierrel F,Zoll J,Dal Peraro M,Kannan N,Bingman CA,Coon JJ,Isope P,Puccio H,Pagliarini DJ

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COQ8B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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