gRNAs
The following TMC7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMC7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu49200 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001300732.1 | |
| Accession Version | NM_001300732.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform c | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. On Jul 11, 2014 this sequence version replaced XM_005255597.1. Transcript Variant: This variant (3) encodes the longest isoform (c). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.15912.1, SRR1660803.135321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001287661.1 |
| CDS | 131..2407 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001300732.1 |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08797 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001160364.2 | |
| Accession Version | NM_001160364.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-23 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. On Mar 1, 2014 this sequence version replaced NM_001160364.1. Transcript Variant: This variant (2) differs in both UTR's and the coding region but maintains the reading frame, compared to variant 3. This results in a protein that is shorter than isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CR933669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAAGTATC TCTCCGAATG GGACCAGTGG AAGCGGTATA GCAGCAAGTC TTGGAAGAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001153836.1 |
| CDS | 559..2400 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001160364.2 |
1 | ATGAAGTATC TCTCCGAATG GGACCAGTGG AAGCGGTATA GCAGCAAGTC TTGGAAGAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu100764 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001324263.1 , NM_001324268.1 | |
| Accession Version | NM_001324263.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform d | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.244120.1, SRR1660803.94312.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCGGCAGA AAATAGCAGA AAGGACCTCA GAAGAAACAA TACGCATTTA CTCTTTGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001311192.1 |
| CDS | 1144..2289 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001324263.1 |
1 | ATGCGGCAGA AAATAGCAGA AAGGACCTCA GAAGAAACAA TACGCATTTA CTCTTTGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu100764 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001324263.1 , NM_001324268.1 | |
| Accession Version | NM_001324268.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform d | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.75152.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCGGCAGA AAATAGCAGA AAGGACCTCA GAAGAAACAA TACGCATTTA CTCTTTGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001311197.1 |
| CDS | 1009..2154 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001324268.1 |
1 | ATGCGGCAGA AAATAGCAGA AAGGACCTCA GAAGAAACAA TACGCATTTA CTCTTTGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08814 | |
| Clone ID Related Accession (Same CDS sequence) | NM_024847.4 | |
| Accession Version | NM_024847.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. On Mar 1, 2014 this sequence version replaced NM_024847.3. Transcript Variant: This variant (1) includes an alternate penultimate exon, compared to variant 3, resulting in an alternate 3' coding region and longer 3' UTR. It encodes isoform a which has a distinct C-terminus, compared to isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.185845.1, SRR1803617.236206.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000304381.10/ ENSP00000304710.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_079123.3 |
| CDS | 131..2302 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_024847.4 |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu100765 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001324265.1 | |
| Accession Version | NM_001324265.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | transmembrane channel-like protein 7 isoform e | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099518.3. On Apr 28, 2016 this sequence version replaced XM_011545959.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.32771.1, SRR1803611.33278.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001311194.1 |
| CDS | 131..2146 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001324265.1 |
1 | ATGAGCGAGT CCAGCGGCAG TGCGCTCCAG CCCGGCAGGC CCAGCCGGCA GCCGGCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. |
Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. |
TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins. |
