ELMO3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ELMO3
Entrez Gene ID	79767
Full Name	engulfment and cell motility 3
Synonyms	CED-12,CED12,ELMO-3
General protein information	Preferred Names engulfment and cell motility 3 Names engulfment and cell motility protein 3 ced-12 homolog 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008].
Disorder MIM:	606422

mRNA and Protein(s)

mRNA	Protein	Name
XM_024450447.1	XP_024306215.1	engulfment and cell motility protein 3 isoform X1
NM_024712.3	NP_078988.2	engulfment and cell motility protein 3
NM_024712.5	NP_078988.3	engulfment and cell motility protein 3
NM_024712.4	NP_078988.3	engulfment and cell motility protein 3

Pathways from BioSystems

Homologies

	LOC698664	XP_002808347.1
Rattus norvegicus (Norway rat)	Elmo3	NP_001025199.1
Xenopus tropicalis (tropical clawed frog)	elmo3	XP_002931693.1
Canis lupus familiaris (dog)	ELMO3	XP_005620906.1
Bos taurus (cattle)	ELMO3	NP_001095561.1
Homo sapiens (human)	ELMO3	NP_078988.2
Mus musculus (house mouse)	Elmo3	NP_766348.3
Pan troglodytes (chimpanzee)	ELMO3	XP_001162282.1
Gallus gallus (chicken)	ELMO3	NP_001243730.1
Danio rerio (zebrafish)	im:7143453	XP_003201479.2

Gene Ontology
Bibliography

Related articles in PubMed

ELMO3 expression indicates a poor prognosis in head and neck squamous cell carcinoma - a short report.
Kadletz L, Heiduschka G, Wiebringhaus R, Gurnhofer E, Kotowski U, Haymerle G, Brunner M, Barry C, Kenner L
Cellular oncology (Dordrecht)40(2)193-198(2017 Apr)

Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.
Peng HY, Yu QF, Shen W, Guo CM, Li Z, Zhou XY, Zhou NJ, Min WP, Gao D
International journal of molecular sciences17(12)(2016 Dec)

ELMO3 is a novel biomarker for diagnosis and prognosis of non-small cell lung cancer.
Fan W, Yang H, Xue H, Sun Y, Zhang J
International journal of clinical and experimental pathology8(5)5503-8(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The purpose of this study was to asses ELMO3 expression in postoperatively irradiated head and neck squamous cell carcinoma patients.
Title: ELMO3 expression indicates a poor prognosis in head and neck squamous cell carcinoma - a short report.

the silencing of ELMO3 inhibited cell proliferation, invasion, metastasis, and F-actin polymerization, and induced Gap 1 (G1) phase cell cycle arrest, demonstrating that ELMO3 is involved in the processes of growth, invasion and metastasis of Colorectal Cancer
Title: Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.

The over-expression of ELMO3 was a potential diagnostic and prognostic marker for non-small cell lung cancer.
Title: ELMO3 is a novel biomarker for diagnosis and prognosis of non-small cell lung cancer.

The present study reports the first characterization of the ELMO3 promoter and suggests a significant role of CDX2 in the basal transcriptional regulation of the intestine-specific expression of ELMO3, possibly through interaction with SP1.
Title: Control of intestinal promoter activity of the cellular migratory regulator gene ELMO3 by CDX2 and SP1.

The following ELMO3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELMO3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04196	NM_024712.3 Latest version!	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$545.30 $779.00
OHu106821	NM_024712.5 Latest version!	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu104207	XM_024450447.1 Latest version!	Homo sapiens engulfment and cell motility 3 (ELMO3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu106821	NM_024712.4	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ELMO3 ( NM_024712.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078988.2 Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

Price & Availability↑

CloneID	OHu04196
Clone ID Related Accession (Same CDS sequence)	NM_024712.3
Accession Version	NM_024712.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	engulfment and cell motility protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA872517.1, BC034410.1 and AI955864.1. On Feb 15, 2006 this sequence version replaced NM_024712.2. ##Evidence-Data-START## Transcript exon combination :: AK300976.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGGA GCAGCAGTCT GGGCCGCGAG TGCGGGACAC CGAGGTCAGG TCTCGGAAAG 
GGAGGACCTC CTCGTCCCCA GGGGCCCCAG GCCAGGTGCA CCCTTGGCCG CAGGTGCACG 
GTCTCCGGAA AGTGCAGGCG CCCACGTCCC AGCTGGACCA TGGCGCCTCC GCGGAACGTG 
GTGAAGATTG CCATCAAGAT GCGTGACGCC ATCCCGCAGC TCATCCAGCT GGACCAGGCG 
AAGCCCCTGG CCGCTGTGCT GAAGGAGGTG TGCGACGCGT GGAGCCTGAC GCACTCTGAG 
CGTTACGCCC TGCAGTTTGC GGATGGGCAC CGGAGATACA TCACCGAGAA TAACCGCGCG 
GAGATCAAGA ATGGCAGCAT CCTGTGCCTC AGCACGGCCC CAGACCTTGA GGCTGAGCAG 
CTCTTGGGTG GGCTGCAGAG TAACAGTCCT GAAGGGCGCC GGGAAGCCCT GAGGCGCCTT 
GTTCCGCTGG CCTCGGACAT GATCTTTGCC AGGGAGGTCA TCAGCCGTAA TGGGCTCCAG 
ATACTAGGCA CCATCATTGA AGATGGGGAC GACCTAGGAG AGGTGCTGGC CCTCAGCCTG 
AGGGCCTTCT CAGAGCTCAT GGAGCACGGC GTGGTGTCCT GGGAGACTCT GAGCATCCCC 
TTTGTGAGGA AGGTGGTGTG CTACGTGAAC ATGAACCTCA TGGATGCCTC CGTGCCTCCC 
CTGGCCCTTG GGCTGCTGGA GAGTGTGACC TTGAGCAGCC CAGCCCTGGG CCAGCTGGTC 
AAGAGCGAGG TGCCCCTGGA TAGGCTGCTG GTGCACCTAC AGGTGATGAA CCAGCAGCTG 
CAAACCAAGG CCATGGCCCT GCTGACAGCC TTGCTGCAGG GGGCCAGCCC TGTGGAACGC 
AAGCACATGC TTGACTATCT TTGGCAGAGG AACCTTCGCC AGTTCATCTA TAAGAACATC 
ATCCACAGTG CAGCACCAAT GGGCGACGAG ATGGCTCATC ACCTGTACGT ACTGCAGGCT 
CTCATGCTGG GGCTGCTGGA GCCGCGCATG CGGACGCCCC TGGACCCCTA CAGCCAGGAG 
CAGCGGGAGC AGCTGCAGGT CCTACGCCAG GCTGCCTTCG AGGTGGAGGG GGAGTCCTCG 
GGTGCCGGGC TAAGTGCTGA CCGTCGCCGT TCCCTCTGTG CCCGAGAGTT CCGCAAACTG 
GGCTTTTCTA ACAGCAACCC AGCACAGGAC CTGGAGCGCG TGCCCCCCGG TCTGCTGGCC 
CTGGACAACA TGTTGTACTT CTCCAGAAAC GCGCCCAGCG CGTACAGCCG GTTTGTGTTG 
GAGAACAGCA GCCGCGAGGA CAAGCACGAG TGCCCCTTTG CCCGGGGCAG CATCCAGCTG 
ACGGTGCTGC TGTGTGAGCT GCTCCGTGTT GGGGAGCCCT GCTCTGAGAC AGCCCAGGAC 
TTCTCACCCA TGTTCTTCGG CCAAGACCAG AGCTTCCACG AGCTCTTCTG TGTGGGCATC 
CAGCTGTTGA ATAAGACCTG GAAGGAGATG CGGGCTACAC AGGAGGACTT CGACAAGGTC 
ATGCAGGTGG TGCGGGAGCA GCTGGCCCGC ACTCTGGCCC TGAAGCCCAC TTCCCTGGAG 
CTCTTCCGAA CCAAGGTGAA TGCGCTCACT TATGGGGAGG TGCTGCGGCT GCGGCAGACT 
GAACGGCTGC ACCAGGAGGG CACACTGGCT CCCCCTATAC TGGAGCTGCG GGAGAAGCTG 
AAGCCAGAGC TCATGGGCCT GATCCGCCAG CAGCGCTTGC TCCGCCTCTG TGAGGGGACG 
CTCTTCCGCA AGATCAGCAG CCGGCGGCGC CAGGATAAGC TGTGGTTCTG CTGCCTGTCC 
CCCAACCACA AGCTGCTGCA GTACGGAGAC ATGGAGGAGG GCGCCAGCCC GCCTACCCTG 
GAGAGTCTGC CCGAGCAACT CCCTGTGGCC GACATGAGGG CACTCCTGAC AGGCAAGGAC 
TGCCCCCATG TCCGGGAGAA GGGCTCCGGG AAGCAGAACA AGGACCTCTA TGAGTTGGCC 
TTCTCAATCA GCTATGACCG TGGGGAGGAG GAAGCGTACC TCAACTTCAT TGCCCCCTCC 
AAGCGGGAGT TCTACCTGTG GACAGATGGG CTCAGTGCCT TGCTGGGCAG TCCCATGGGC 
AGCGAGCAGA CACGGCTGGA CCTGGAGCAG CTGCTGACCA TGGAGACCAA GCTGCGTCTG 
CTGGAGCTGG AGAACGTGCC CATCCCCGAG CGGCCACCCC CTGTGCCCCC ACCCCCCACC 
AACTTCAACT TCTGCTATGA CTGCAGCATC GCTGAACCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078988.2
CDS	44..2365
Translation	MARSSSLGRECGTPRSGLGKGGPPRPQGPQARCTLGRRCTVSGKCRRPRPSWTMAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRYITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREVISRNGLQILGTIIEDGDDLGEVLALSLRAFSELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP

Target ORF information:

RefSeq Version	NM_024712.3
Organism	Homo sapiens(human)
Definition	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024712.3

ORF Insert Sequence:

ATGGCCAGGA GCAGCAGTCT GGGCCGCGAG TGCGGGACAC CGAGGTCAGG TCTCGGAAAG 
GGAGGACCTC CTCGTCCCCA GGGGCCCCAG GCCAGGTGCA CCCTTGGCCG CAGGTGCACG 
GTCTCCGGAA AGTGCAGGCG CCCACGTCCC AGCTGGACCA TGGCGCCTCC GCGGAACGTG 
GTGAAGATTG CCATCAAGAT GCGTGACGCC ATCCCGCAGC TCATCCAGCT GGACCAGGCG 
AAGCCCCTGG CCGCTGTGCT GAAGGAGGTG TGCGACGCGT GGAGCCTGAC GCACTCTGAG 
CGTTACGCCC TGCAGTTTGC GGATGGGCAC CGGAGATACA TCACCGAGAA TAACCGCGCG 
GAGATCAAGA ATGGCAGCAT CCTGTGCCTC AGCACGGCCC CAGACCTTGA GGCTGAGCAG 
CTCTTGGGTG GGCTGCAGAG TAACAGTCCT GAAGGGCGCC GGGAAGCCCT GAGGCGCCTT 
GTTCCGCTGG CCTCGGACAT GATCTTTGCC AGGGAGGTCA TCAGCCGTAA TGGGCTCCAG 
ATACTAGGCA CCATCATTGA AGATGGGGAC GACCTAGGAG AGGTGCTGGC CCTCAGCCTG 
AGGGCCTTCT CAGAGCTCAT GGAGCACGGC GTGGTGTCCT GGGAGACTCT GAGCATCCCC 
TTTGTGAGGA AGGTGGTGTG CTACGTGAAC ATGAACCTCA TGGATGCCTC CGTGCCTCCC 
CTGGCCCTTG GGCTGCTGGA GAGTGTGACC TTGAGCAGCC CAGCCCTGGG CCAGCTGGTC 
AAGAGCGAGG TGCCCCTGGA TAGGCTGCTG GTGCACCTAC AGGTGATGAA CCAGCAGCTG 
CAAACCAAGG CCATGGCCCT GCTGACAGCC TTGCTGCAGG GGGCCAGCCC TGTGGAACGC 
AAGCACATGC TTGACTATCT TTGGCAGAGG AACCTTCGCC AGTTCATCTA TAAGAACATC 
ATCCACAGTG CAGCACCAAT GGGCGACGAG ATGGCTCATC ACCTGTACGT ACTGCAGGCT 
CTCATGCTGG GGCTGCTGGA GCCGCGCATG CGGACGCCCC TGGACCCCTA CAGCCAGGAG 
CAGCGGGAGC AGCTGCAGGT CCTACGCCAG GCTGCCTTCG AGGTGGAGGG GGAGTCCTCG 
GGTGCCGGGC TAAGTGCTGA CCGTCGCCGT TCCCTCTGTG CCCGAGAGTT CCGCAAACTG 
GGCTTTTCTA ACAGCAACCC AGCACAGGAC CTGGAGCGCG TGCCCCCCGG TCTGCTGGCC 
CTGGACAACA TGTTGTACTT CTCCAGAAAC GCGCCCAGCG CGTACAGCCG GTTTGTGTTG 
GAGAACAGCA GCCGCGAGGA CAAGCACGAG TGCCCCTTTG CCCGGGGCAG CATCCAGCTG 
ACGGTGCTGC TGTGTGAGCT GCTCCGTGTT GGGGAGCCCT GCTCTGAGAC AGCCCAGGAC 
TTCTCACCCA TGTTCTTCGG CCAAGACCAG AGCTTCCACG AGCTCTTCTG TGTGGGCATC 
CAGCTGTTGA ATAAGACCTG GAAGGAGATG CGGGCTACAC AGGAGGACTT CGACAAGGTC 
ATGCAGGTGG TGCGGGAGCA GCTGGCCCGC ACTCTGGCCC TGAAGCCCAC TTCCCTGGAG 
CTCTTCCGAA CCAAGGTGAA TGCGCTCACT TATGGGGAGG TGCTGCGGCT GCGGCAGACT 
GAACGGCTGC ACCAGGAGGG CACACTGGCT CCCCCTATAC TGGAGCTGCG GGAGAAGCTG 
AAGCCAGAGC TCATGGGCCT GATCCGCCAG CAGCGCTTGC TCCGCCTCTG TGAGGGGACG 
CTCTTCCGCA AGATCAGCAG CCGGCGGCGC CAGGATAAGC TGTGGTTCTG CTGCCTGTCC 
CCCAACCACA AGCTGCTGCA GTACGGAGAC ATGGAGGAGG GCGCCAGCCC GCCTACCCTG 
GAGAGTCTGC CCGAGCAACT CCCTGTGGCC GACATGAGGG CACTCCTGAC AGGCAAGGAC 
TGCCCCCATG TCCGGGAGAA GGGCTCCGGG AAGCAGAACA AGGACCTCTA TGAGTTGGCC 
TTCTCAATCA GCTATGACCG TGGGGAGGAG GAAGCGTACC TCAACTTCAT TGCCCCCTCC 
AAGCGGGAGT TCTACCTGTG GACAGATGGG CTCAGTGCCT TGCTGGGCAG TCCCATGGGC 
AGCGAGCAGA CACGGCTGGA CCTGGAGCAG CTGCTGACCA TGGAGACCAA GCTGCGTCTG 
CTGGAGCTGG AGAACGTGCC CATCCCCGAG CGGCCACCCC CTGTGCCCCC ACCCCCCACC 
AACTTCAACT TCTGCTATGA CTGCAGCATC GCTGAACCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELMO3 ( NM_024712.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_078988.3 Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

Price & Availability↑

CloneID	OHu106821
Clone ID Related Accession (Same CDS sequence)	NM_024712.5 , NM_024712.4
Accession Version	NM_024712.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	engulfment and cell motility protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA872517.1, AC040160.4 and BC034410.1. On May 17, 2019 this sequence version replaced NM_024712.4. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation. ##Evidence-Data-START## Transcript exon combination :: AK300976.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved MANE Ensembl match :: ENST00000393997.8/ ENSP00000377566.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCTC CGCGGAACGT GGTGAAGATT GCCATCAAGA TGCGTGACGC CATCCCGCAG 
CTCATCCAGC TGGACCAGGC GAAGCCCCTG GCCGCTGTGC TGAAGGAGGT GTGCGACGCG 
TGGAGCCTGA CGCACTCTGA GCGTTACGCC CTGCAGTTTG CGGATGGGCA CCGGAGATAC 
ATCACCGAGA ATAACCGCGC GGAGATCAAG AATGGCAGCA TCCTGTGCCT CAGCACGGCC 
CCAGACCTTG AGGCTGAGCA GCTCTTGGGT GGGCTGCAGA GTAACAGTCC TGAAGGGCGC 
CGGGAAGCCC TGAGGCGCCT TGTTCCGCTG GCCTCGGACA TGATCTTTGC CAGGGAGGTC 
ATCAGCCGTA ATGGGCTCCA GATACTAGGC ACCATCATTG AAGATGGGGA CGACCTAGGA 
GAGGTGCTGG CCCTCAGCCT GAGGGCCTTC TCAGAGCTCA TGGAGCACGG CGTGGTGTCC 
TGGGAGACTC TGAGCATCCC CTTTGTGAGG AAGGTGGTGT GCTACGTGAA CATGAACCTC 
ATGGATGCCT CCGTGCCTCC CCTGGCCCTT GGGCTGCTGG AGAGTGTGAC CTTGAGCAGC 
CCAGCCCTGG GCCAGCTGGT CAAGAGCGAG GTGCCCCTGG ATAGGCTGCT GGTGCACCTA 
CAGGTGATGA ACCAGCAGCT GCAAACCAAG GCCATGGCCC TGCTGACAGC CTTGCTGCAG 
GGGGCCAGCC CTGTGGAACG CAAGCACATG CTTGACTATC TTTGGCAGAG GAACCTTCGC 
CAGTTCATCT ATAAGAACAT CATCCACAGT GCAGCACCAA TGGGCGACGA GATGGCTCAT 
CACCTGTACG TACTGCAGGC TCTCATGCTG GGGCTGCTGG AGCCGCGCAT GCGGACGCCC 
CTGGACCCCT ACAGCCAGGA GCAGCGGGAG CAGCTGCAGG TCCTACGCCA GGCTGCCTTC 
GAGGTGGAGG GGGAGTCCTC GGGTGCCGGG CTAAGTGCTG ACCGTCGCCG TTCCCTCTGT 
GCCCGAGAGT TCCGCAAACT GGGCTTTTCT AACAGCAACC CAGCACAGGA CCTGGAGCGC 
GTGCCCCCCG GTCTGCTGGC CCTGGACAAC ATGTTGTACT TCTCCAGAAA CGCGCCCAGC 
GCGTACAGCC GGTTTGTGTT GGAGAACAGC AGCCGCGAGG ACAAGCACGA GTGCCCCTTT 
GCCCGGGGCA GCATCCAGCT GACGGTGCTG CTGTGTGAGC TGCTCCGTGT TGGGGAGCCC 
TGCTCTGAGA CAGCCCAGGA CTTCTCACCC ATGTTCTTCG GCCAAGACCA GAGCTTCCAC 
GAGCTCTTCT GTGTGGGCAT CCAGCTGTTG AATAAGACCT GGAAGGAGAT GCGGGCTACA 
CAGGAGGACT TCGACAAGGT CATGCAGGTG GTGCGGGAGC AGCTGGCCCG CACTCTGGCC 
CTGAAGCCCA CTTCCCTGGA GCTCTTCCGA ACCAAGGTGA ATGCGCTCAC TTATGGGGAG 
GTGCTGCGGC TGCGGCAGAC TGAACGGCTG CACCAGGAGG GCACACTGGC TCCCCCTATA 
CTGGAGCTGC GGGAGAAGCT GAAGCCAGAG CTCATGGGCC TGATCCGCCA GCAGCGCTTG 
CTCCGCCTCT GTGAGGGGAC GCTCTTCCGC AAGATCAGCA GCCGGCGGCG CCAGGATAAG 
CTGTGGTTCT GCTGCCTGTC CCCCAACCAC AAGCTGCTGC AGTACGGAGA CATGGAGGAG 
GGCGCCAGCC CGCCTACCCT GGAGAGTCTG CCCGAGCAAC TCCCTGTGGC CGACATGAGG 
GCACTCCTGA CAGGCAAGGA CTGCCCCCAT GTCCGGGAGA AGGGCTCCGG GAAGCAGAAC 
AAGGACCTCT ATGAGTTGGC CTTCTCAATC AGCTATGACC GTGGGGAGGA GGAAGCGTAC 
CTCAACTTCA TTGCCCCCTC CAAGCGGGAG TTCTACCTGT GGACAGATGG GCTCAGTGCC 
TTGCTGGGCA GTCCCATGGG CAGCGAGCAG ACACGGCTGG ACCTGGAGCA GCTGCTGACC 
ATGGAGACCA AGCTGCGTCT GCTGGAGCTG GAGAACGTGC CCATCCCCGA GCGGCCACCC 
CCTGTGCCCC CACCCCCCAC CAACTTCAAC TTCTGCTATG ACTGCAGCAT CGCTGAACCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078988.3
CDS	197..2359
Translation	MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRYITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREVISRNGLQILGTIIEDGDDLGEVLALSLRAFSELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP

Target ORF information:

RefSeq Version	NM_024712.5
Organism	Homo sapiens(human)
Definition	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024712.5

ORF Insert Sequence:

ATGGCGCCTC CGCGGAACGT GGTGAAGATT GCCATCAAGA TGCGTGACGC CATCCCGCAG 
CTCATCCAGC TGGACCAGGC GAAGCCCCTG GCCGCTGTGC TGAAGGAGGT GTGCGACGCG 
TGGAGCCTGA CGCACTCTGA GCGTTACGCC CTGCAGTTTG CGGATGGGCA CCGGAGATAC 
ATCACCGAGA ATAACCGCGC GGAGATCAAG AATGGCAGCA TCCTGTGCCT CAGCACGGCC 
CCAGACCTTG AGGCTGAGCA GCTCTTGGGT GGGCTGCAGA GTAACAGTCC TGAAGGGCGC 
CGGGAAGCCC TGAGGCGCCT TGTTCCGCTG GCCTCGGACA TGATCTTTGC CAGGGAGGTC 
ATCAGCCGTA ATGGGCTCCA GATACTAGGC ACCATCATTG AAGATGGGGA CGACCTAGGA 
GAGGTGCTGG CCCTCAGCCT GAGGGCCTTC TCAGAGCTCA TGGAGCACGG CGTGGTGTCC 
TGGGAGACTC TGAGCATCCC CTTTGTGAGG AAGGTGGTGT GCTACGTGAA CATGAACCTC 
ATGGATGCCT CCGTGCCTCC CCTGGCCCTT GGGCTGCTGG AGAGTGTGAC CTTGAGCAGC 
CCAGCCCTGG GCCAGCTGGT CAAGAGCGAG GTGCCCCTGG ATAGGCTGCT GGTGCACCTA 
CAGGTGATGA ACCAGCAGCT GCAAACCAAG GCCATGGCCC TGCTGACAGC CTTGCTGCAG 
GGGGCCAGCC CTGTGGAACG CAAGCACATG CTTGACTATC TTTGGCAGAG GAACCTTCGC 
CAGTTCATCT ATAAGAACAT CATCCACAGT GCAGCACCAA TGGGCGACGA GATGGCTCAT 
CACCTGTACG TACTGCAGGC TCTCATGCTG GGGCTGCTGG AGCCGCGCAT GCGGACGCCC 
CTGGACCCCT ACAGCCAGGA GCAGCGGGAG CAGCTGCAGG TCCTACGCCA GGCTGCCTTC 
GAGGTGGAGG GGGAGTCCTC GGGTGCCGGG CTAAGTGCTG ACCGTCGCCG TTCCCTCTGT 
GCCCGAGAGT TCCGCAAACT GGGCTTTTCT AACAGCAACC CAGCACAGGA CCTGGAGCGC 
GTGCCCCCCG GTCTGCTGGC CCTGGACAAC ATGTTGTACT TCTCCAGAAA CGCGCCCAGC 
GCGTACAGCC GGTTTGTGTT GGAGAACAGC AGCCGCGAGG ACAAGCACGA GTGCCCCTTT 
GCCCGGGGCA GCATCCAGCT GACGGTGCTG CTGTGTGAGC TGCTCCGTGT TGGGGAGCCC 
TGCTCTGAGA CAGCCCAGGA CTTCTCACCC ATGTTCTTCG GCCAAGACCA GAGCTTCCAC 
GAGCTCTTCT GTGTGGGCAT CCAGCTGTTG AATAAGACCT GGAAGGAGAT GCGGGCTACA 
CAGGAGGACT TCGACAAGGT CATGCAGGTG GTGCGGGAGC AGCTGGCCCG CACTCTGGCC 
CTGAAGCCCA CTTCCCTGGA GCTCTTCCGA ACCAAGGTGA ATGCGCTCAC TTATGGGGAG 
GTGCTGCGGC TGCGGCAGAC TGAACGGCTG CACCAGGAGG GCACACTGGC TCCCCCTATA 
CTGGAGCTGC GGGAGAAGCT GAAGCCAGAG CTCATGGGCC TGATCCGCCA GCAGCGCTTG 
CTCCGCCTCT GTGAGGGGAC GCTCTTCCGC AAGATCAGCA GCCGGCGGCG CCAGGATAAG 
CTGTGGTTCT GCTGCCTGTC CCCCAACCAC AAGCTGCTGC AGTACGGAGA CATGGAGGAG 
GGCGCCAGCC CGCCTACCCT GGAGAGTCTG CCCGAGCAAC TCCCTGTGGC CGACATGAGG 
GCACTCCTGA CAGGCAAGGA CTGCCCCCAT GTCCGGGAGA AGGGCTCCGG GAAGCAGAAC 
AAGGACCTCT ATGAGTTGGC CTTCTCAATC AGCTATGACC GTGGGGAGGA GGAAGCGTAC 
CTCAACTTCA TTGCCCCCTC CAAGCGGGAG TTCTACCTGT GGACAGATGG GCTCAGTGCC 
TTGCTGGGCA GTCCCATGGG CAGCGAGCAG ACACGGCTGG ACCTGGAGCA GCTGCTGACC 
ATGGAGACCA AGCTGCGTCT GCTGGAGCTG GAGAACGTGC CCATCCCCGA GCGGCCACCC 
CCTGTGCCCC CACCCCCCAC CAACTTCAAC TTCTGCTATG ACTGCAGCAT CGCTGAACCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELMO3 ( NM_024712.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078988.3 Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

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CloneID	OHu106821
Clone ID Related Accession (Same CDS sequence)	NM_024712.5 , NM_024712.4
Accession Version	NM_024712.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Homo sapiens(human)
Product	engulfment and cell motility protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA872517.1, AC040160.4, BC034410.1, AI955864.1 and BI468420.1. On Aug 11, 2018 this sequence version replaced NM_024712.3. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation. ##Evidence-Data-START## Transcript exon combination :: AK300976.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCTC CGCGGAACGT GGTGAAGATT GCCATCAAGA TGCGTGACGC CATCCCGCAG 
CTCATCCAGC TGGACCAGGC GAAGCCCCTG GCCGCTGTGC TGAAGGAGGT GTGCGACGCG 
TGGAGCCTGA CGCACTCTGA GCGTTACGCC CTGCAGTTTG CGGATGGGCA CCGGAGATAC 
ATCACCGAGA ATAACCGCGC GGAGATCAAG AATGGCAGCA TCCTGTGCCT CAGCACGGCC 
CCAGACCTTG AGGCTGAGCA GCTCTTGGGT GGGCTGCAGA GTAACAGTCC TGAAGGGCGC 
CGGGAAGCCC TGAGGCGCCT TGTTCCGCTG GCCTCGGACA TGATCTTTGC CAGGGAGGTC 
ATCAGCCGTA ATGGGCTCCA GATACTAGGC ACCATCATTG AAGATGGGGA CGACCTAGGA 
GAGGTGCTGG CCCTCAGCCT GAGGGCCTTC TCAGAGCTCA TGGAGCACGG CGTGGTGTCC 
TGGGAGACTC TGAGCATCCC CTTTGTGAGG AAGGTGGTGT GCTACGTGAA CATGAACCTC 
ATGGATGCCT CCGTGCCTCC CCTGGCCCTT GGGCTGCTGG AGAGTGTGAC CTTGAGCAGC 
CCAGCCCTGG GCCAGCTGGT CAAGAGCGAG GTGCCCCTGG ATAGGCTGCT GGTGCACCTA 
CAGGTGATGA ACCAGCAGCT GCAAACCAAG GCCATGGCCC TGCTGACAGC CTTGCTGCAG 
GGGGCCAGCC CTGTGGAACG CAAGCACATG CTTGACTATC TTTGGCAGAG GAACCTTCGC 
CAGTTCATCT ATAAGAACAT CATCCACAGT GCAGCACCAA TGGGCGACGA GATGGCTCAT 
CACCTGTACG TACTGCAGGC TCTCATGCTG GGGCTGCTGG AGCCGCGCAT GCGGACGCCC 
CTGGACCCCT ACAGCCAGGA GCAGCGGGAG CAGCTGCAGG TCCTACGCCA GGCTGCCTTC 
GAGGTGGAGG GGGAGTCCTC GGGTGCCGGG CTAAGTGCTG ACCGTCGCCG TTCCCTCTGT 
GCCCGAGAGT TCCGCAAACT GGGCTTTTCT AACAGCAACC CAGCACAGGA CCTGGAGCGC 
GTGCCCCCCG GTCTGCTGGC CCTGGACAAC ATGTTGTACT TCTCCAGAAA CGCGCCCAGC 
GCGTACAGCC GGTTTGTGTT GGAGAACAGC AGCCGCGAGG ACAAGCACGA GTGCCCCTTT 
GCCCGGGGCA GCATCCAGCT GACGGTGCTG CTGTGTGAGC TGCTCCGTGT TGGGGAGCCC 
TGCTCTGAGA CAGCCCAGGA CTTCTCACCC ATGTTCTTCG GCCAAGACCA GAGCTTCCAC 
GAGCTCTTCT GTGTGGGCAT CCAGCTGTTG AATAAGACCT GGAAGGAGAT GCGGGCTACA 
CAGGAGGACT TCGACAAGGT CATGCAGGTG GTGCGGGAGC AGCTGGCCCG CACTCTGGCC 
CTGAAGCCCA CTTCCCTGGA GCTCTTCCGA ACCAAGGTGA ATGCGCTCAC TTATGGGGAG 
GTGCTGCGGC TGCGGCAGAC TGAACGGCTG CACCAGGAGG GCACACTGGC TCCCCCTATA 
CTGGAGCTGC GGGAGAAGCT GAAGCCAGAG CTCATGGGCC TGATCCGCCA GCAGCGCTTG 
CTCCGCCTCT GTGAGGGGAC GCTCTTCCGC AAGATCAGCA GCCGGCGGCG CCAGGATAAG 
CTGTGGTTCT GCTGCCTGTC CCCCAACCAC AAGCTGCTGC AGTACGGAGA CATGGAGGAG 
GGCGCCAGCC CGCCTACCCT GGAGAGTCTG CCCGAGCAAC TCCCTGTGGC CGACATGAGG 
GCACTCCTGA CAGGCAAGGA CTGCCCCCAT GTCCGGGAGA AGGGCTCCGG GAAGCAGAAC 
AAGGACCTCT ATGAGTTGGC CTTCTCAATC AGCTATGACC GTGGGGAGGA GGAAGCGTAC 
CTCAACTTCA TTGCCCCCTC CAAGCGGGAG TTCTACCTGT GGACAGATGG GCTCAGTGCC 
TTGCTGGGCA GTCCCATGGG CAGCGAGCAG ACACGGCTGG ACCTGGAGCA GCTGCTGACC 
ATGGAGACCA AGCTGCGTCT GCTGGAGCTG GAGAACGTGC CCATCCCCGA GCGGCCACCC 
CCTGTGCCCC CACCCCCCAC CAACTTCAAC TTCTGCTATG ACTGCAGCAT CGCTGAACCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078988.3
CDS	197..2359
Translation	MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRYITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREVISRNGLQILGTIIEDGDDLGEVLALSLRAFSELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP

Target ORF information:

RefSeq Version	NM_024712.4
Organism	Homo sapiens(human)
Definition	Homo sapiens engulfment and cell motility 3 (ELMO3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024712.4

ORF Insert Sequence:

ATGGCGCCTC CGCGGAACGT GGTGAAGATT GCCATCAAGA TGCGTGACGC CATCCCGCAG 
CTCATCCAGC TGGACCAGGC GAAGCCCCTG GCCGCTGTGC TGAAGGAGGT GTGCGACGCG 
TGGAGCCTGA CGCACTCTGA GCGTTACGCC CTGCAGTTTG CGGATGGGCA CCGGAGATAC 
ATCACCGAGA ATAACCGCGC GGAGATCAAG AATGGCAGCA TCCTGTGCCT CAGCACGGCC 
CCAGACCTTG AGGCTGAGCA GCTCTTGGGT GGGCTGCAGA GTAACAGTCC TGAAGGGCGC 
CGGGAAGCCC TGAGGCGCCT TGTTCCGCTG GCCTCGGACA TGATCTTTGC CAGGGAGGTC 
ATCAGCCGTA ATGGGCTCCA GATACTAGGC ACCATCATTG AAGATGGGGA CGACCTAGGA 
GAGGTGCTGG CCCTCAGCCT GAGGGCCTTC TCAGAGCTCA TGGAGCACGG CGTGGTGTCC 
TGGGAGACTC TGAGCATCCC CTTTGTGAGG AAGGTGGTGT GCTACGTGAA CATGAACCTC 
ATGGATGCCT CCGTGCCTCC CCTGGCCCTT GGGCTGCTGG AGAGTGTGAC CTTGAGCAGC 
CCAGCCCTGG GCCAGCTGGT CAAGAGCGAG GTGCCCCTGG ATAGGCTGCT GGTGCACCTA 
CAGGTGATGA ACCAGCAGCT GCAAACCAAG GCCATGGCCC TGCTGACAGC CTTGCTGCAG 
GGGGCCAGCC CTGTGGAACG CAAGCACATG CTTGACTATC TTTGGCAGAG GAACCTTCGC 
CAGTTCATCT ATAAGAACAT CATCCACAGT GCAGCACCAA TGGGCGACGA GATGGCTCAT 
CACCTGTACG TACTGCAGGC TCTCATGCTG GGGCTGCTGG AGCCGCGCAT GCGGACGCCC 
CTGGACCCCT ACAGCCAGGA GCAGCGGGAG CAGCTGCAGG TCCTACGCCA GGCTGCCTTC 
GAGGTGGAGG GGGAGTCCTC GGGTGCCGGG CTAAGTGCTG ACCGTCGCCG TTCCCTCTGT 
GCCCGAGAGT TCCGCAAACT GGGCTTTTCT AACAGCAACC CAGCACAGGA CCTGGAGCGC 
GTGCCCCCCG GTCTGCTGGC CCTGGACAAC ATGTTGTACT TCTCCAGAAA CGCGCCCAGC 
GCGTACAGCC GGTTTGTGTT GGAGAACAGC AGCCGCGAGG ACAAGCACGA GTGCCCCTTT 
GCCCGGGGCA GCATCCAGCT GACGGTGCTG CTGTGTGAGC TGCTCCGTGT TGGGGAGCCC 
TGCTCTGAGA CAGCCCAGGA CTTCTCACCC ATGTTCTTCG GCCAAGACCA GAGCTTCCAC 
GAGCTCTTCT GTGTGGGCAT CCAGCTGTTG AATAAGACCT GGAAGGAGAT GCGGGCTACA 
CAGGAGGACT TCGACAAGGT CATGCAGGTG GTGCGGGAGC AGCTGGCCCG CACTCTGGCC 
CTGAAGCCCA CTTCCCTGGA GCTCTTCCGA ACCAAGGTGA ATGCGCTCAC TTATGGGGAG 
GTGCTGCGGC TGCGGCAGAC TGAACGGCTG CACCAGGAGG GCACACTGGC TCCCCCTATA 
CTGGAGCTGC GGGAGAAGCT GAAGCCAGAG CTCATGGGCC TGATCCGCCA GCAGCGCTTG 
CTCCGCCTCT GTGAGGGGAC GCTCTTCCGC AAGATCAGCA GCCGGCGGCG CCAGGATAAG 
CTGTGGTTCT GCTGCCTGTC CCCCAACCAC AAGCTGCTGC AGTACGGAGA CATGGAGGAG 
GGCGCCAGCC CGCCTACCCT GGAGAGTCTG CCCGAGCAAC TCCCTGTGGC CGACATGAGG 
GCACTCCTGA CAGGCAAGGA CTGCCCCCAT GTCCGGGAGA AGGGCTCCGG GAAGCAGAAC 
AAGGACCTCT ATGAGTTGGC CTTCTCAATC AGCTATGACC GTGGGGAGGA GGAAGCGTAC 
CTCAACTTCA TTGCCCCCTC CAAGCGGGAG TTCTACCTGT GGACAGATGG GCTCAGTGCC 
TTGCTGGGCA GTCCCATGGG CAGCGAGCAG ACACGGCTGG ACCTGGAGCA GCTGCTGACC 
ATGGAGACCA AGCTGCGTCT GCTGGAGCTG GAGAACGTGC CCATCCCCGA GCGGCCACCC 
CCTGTGCCCC CACCCCCCAC CAACTTCAAC TTCTGCTATG ACTGCAGCAT CGCTGAACCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELMO3 ( XM_024450447.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306215.1 Homo sapiens engulfment and cell motility 3 (ELMO3), transcript variant X1, mRNA.

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CloneID	OHu104207
Clone ID Related Accession (Same CDS sequence)	XM_024450447.1
Accession Version	XM_024450447.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	engulfment and cell motility protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTCA TGGATGCCTC CGTGCCTCCC CTGGCCCTTG GGCTGCTGGA GAGTGTGACC 
TTGAGCAGCC CAGCCCTGGG CCAGCTGGTC AAGAGCGAGG TGCCCCTGGA TAGGCTGCTG 
GTGCACCTAC AGGTGATGAA CCAGCAGCTG CAAACCAAGG CCATGGCCCT GCTGACAGCC 
TTGCTGCAGG GGGCCAGCCC TGTGGAACGC AAGCACATGC TTGACTATCT TTGGCAGAGG 
AACCTTCGCC AGTTCATCTA TAAGAACATC ATCCACAGTG CAGCACCAAT GGGCGACGAG 
ATGGCTCATC ACCTGTACGT ACTGCAGGCT CTCATGCTGG GGCTGCTGGA GCCGCGCATG 
CGGACGCCCC TGGACCCCTA CAGCCAGGAG CAGCGGGAGC AGCTGCAGGT CCTACGCCAG 
GCTGCCTTCG AGGTGGAGGG GGAGTCCTCG GGTGCCGGGC TAAGTGCTGA CCGTCGCCGT 
TCCCTCTGTG CCCGAGAGTT CCGCAAACTG GGCTTTTCTA ACAGCAACCC AGCACAGGAC 
CTGGAGCGCG TGCCCCCCGG TCTGCTGGCC CTGGACAACA TGTTGTACTT CTCCAGAAAC 
GCGCCCAGCG CGTACAGCCG GTTTGTGTTG GAGAACAGCA GCCGCGAGGA CAAGCACGAG 
TGCCCCTTTG CCCGGGGCAG CATCCAGCTG ACGGTGCTGC TGTGTGAGCT GCTCCGTGTT 
GGGGAGCCCT GCTCTGAGAC AGCCCAGGAC TTCTCACCCA TGTTCTTCGG CCAAGACCAG 
AGCTTCCACG AGCTCTTCTG TGTGGGCATC CAGCTGTTGA ATAAGACCTG GAAGGAGATG 
CGGGCTACAC AGGAGGACTT CGACAAGGTC ATGCAGGTGG TGCGGGAGCA GCTGGCCCGC 
ACTCTGGCCC TGAAGCCCAC TTCCCTGGAG CTCTTCCGAA CCAAGGTGAA TGCGCTCACT 
TATGGGGAGG TGCTGCGGCT GCGGCAGACT GAACGGCTGC ACCAGGAGGG CACACTGGCT 
CCCCCTATAC TGGAGCTGCG GGAGAAGCTG AAGCCAGAGC TCATGGGCCT GATCCGCCAG 
CAGCGCTTGC TCCGCCTCTG TGAGGGGACG CTCTTCCGCA AGATCAGCAG CCGGCGGCGC 
CAGGATAAGC TGTGGTTCTG CTGCCTGTCC CCCAACCACA AGCTGCTGCA GTACGGAGAC 
ATGGAGGAGG GCGCCAGCCC GCCTACCCTG GAGAGTCTGC CCGAGCAACT CCCTGTGGCC 
GACATGAGGG CACTCCTGAC AGGCAAGGAC TGCCCCCATG TCCGGGAGAA GGGCTCCGGG 
AAGCAGAACA AGGACCTCTA TGAGTTGGCC TTCTCAATCA GCTATGACCG TGGGGAGGAG 
GAAGCGTACC TCAACTTCAT TGCCCCCTCC AAGCGGGAGT TCTACCTGTG GACAGATGGG 
CTCAGTGCCT TGCTGGGCAG TCCCATGGGC AGCGAGCAGA CACGGCTGGA CCTGGAGCAG 
CTGCTGACCA TGGAGACCAA GCTGCGTCTG CTGGAGCTGG AGAACGTGCC CATCCCCGAG 
CGGCCACCCC CTGTGCCCCC ACCCCCCACC AACTTCAACT TCTGCTATGA CTGCAGCATC 
GCTGAACCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306215.1
CDS	331..1962
Translation	MNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP

Target ORF information:

RefSeq Version	XM_024450447.1
Organism	Homo sapiens(human)
Definition	Homo sapiens engulfment and cell motility 3 (ELMO3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450447.1

ORF Insert Sequence:

ATGAACCTCA TGGATGCCTC CGTGCCTCCC CTGGCCCTTG GGCTGCTGGA GAGTGTGACC 
TTGAGCAGCC CAGCCCTGGG CCAGCTGGTC AAGAGCGAGG TGCCCCTGGA TAGGCTGCTG 
GTGCACCTAC AGGTGATGAA CCAGCAGCTG CAAACCAAGG CCATGGCCCT GCTGACAGCC 
TTGCTGCAGG GGGCCAGCCC TGTGGAACGC AAGCACATGC TTGACTATCT TTGGCAGAGG 
AACCTTCGCC AGTTCATCTA TAAGAACATC ATCCACAGTG CAGCACCAAT GGGCGACGAG 
ATGGCTCATC ACCTGTACGT ACTGCAGGCT CTCATGCTGG GGCTGCTGGA GCCGCGCATG 
CGGACGCCCC TGGACCCCTA CAGCCAGGAG CAGCGGGAGC AGCTGCAGGT CCTACGCCAG 
GCTGCCTTCG AGGTGGAGGG GGAGTCCTCG GGTGCCGGGC TAAGTGCTGA CCGTCGCCGT 
TCCCTCTGTG CCCGAGAGTT CCGCAAACTG GGCTTTTCTA ACAGCAACCC AGCACAGGAC 
CTGGAGCGCG TGCCCCCCGG TCTGCTGGCC CTGGACAACA TGTTGTACTT CTCCAGAAAC 
GCGCCCAGCG CGTACAGCCG GTTTGTGTTG GAGAACAGCA GCCGCGAGGA CAAGCACGAG 
TGCCCCTTTG CCCGGGGCAG CATCCAGCTG ACGGTGCTGC TGTGTGAGCT GCTCCGTGTT 
GGGGAGCCCT GCTCTGAGAC AGCCCAGGAC TTCTCACCCA TGTTCTTCGG CCAAGACCAG 
AGCTTCCACG AGCTCTTCTG TGTGGGCATC CAGCTGTTGA ATAAGACCTG GAAGGAGATG 
CGGGCTACAC AGGAGGACTT CGACAAGGTC ATGCAGGTGG TGCGGGAGCA GCTGGCCCGC 
ACTCTGGCCC TGAAGCCCAC TTCCCTGGAG CTCTTCCGAA CCAAGGTGAA TGCGCTCACT 
TATGGGGAGG TGCTGCGGCT GCGGCAGACT GAACGGCTGC ACCAGGAGGG CACACTGGCT 
CCCCCTATAC TGGAGCTGCG GGAGAAGCTG AAGCCAGAGC TCATGGGCCT GATCCGCCAG 
CAGCGCTTGC TCCGCCTCTG TGAGGGGACG CTCTTCCGCA AGATCAGCAG CCGGCGGCGC 
CAGGATAAGC TGTGGTTCTG CTGCCTGTCC CCCAACCACA AGCTGCTGCA GTACGGAGAC 
ATGGAGGAGG GCGCCAGCCC GCCTACCCTG GAGAGTCTGC CCGAGCAACT CCCTGTGGCC 
GACATGAGGG CACTCCTGAC AGGCAAGGAC TGCCCCCATG TCCGGGAGAA GGGCTCCGGG 
AAGCAGAACA AGGACCTCTA TGAGTTGGCC TTCTCAATCA GCTATGACCG TGGGGAGGAG 
GAAGCGTACC TCAACTTCAT TGCCCCCTCC AAGCGGGAGT TCTACCTGTG GACAGATGGG 
CTCAGTGCCT TGCTGGGCAG TCCCATGGGC AGCGAGCAGA CACGGCTGGA CCTGGAGCAG 
CTGCTGACCA TGGAGACCAA GCTGCGTCTG CTGGAGCTGG AGAACGTGCC CATCCCCGAG 
CGGCCACCCC CTGTGCCCCC ACCCCCCACC AACTTCAACT TCTGCTATGA CTGCAGCATC 
GCTGAACCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ELMO3 expression indicates a poor prognosis in head and neck squamous cell carcinoma - a short report.
Cellular oncology (Dordrecht)40(2)193-198(2017 Apr)
Kadletz L,Heiduschka G,Wiebringhaus R,Gurnhofer E,Kotowski U,Haymerle G,Brunner M,Barry C,Kenner L

Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.
International journal of molecular sciences17(12)(2016 Dec)
Peng HY,Yu QF,Shen W,Guo CM,Li Z,Zhou XY,Zhou NJ,Min WP,Gao D

ELMO3 is a novel biomarker for diagnosis and prognosis of non-small cell lung cancer.
International journal of clinical and experimental pathology8(5)5503-8(2015)
Fan W,Yang H,Xue H,Sun Y,Zhang J

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ELMO3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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