ZNF750 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZNF750
Entrez Gene ID	79755
Full Name	zinc finger protein 750
Synonyms	ZFP750
General protein information	Preferred Names zinc finger protein 750 Names zinc finger protein 750 protein ZNF750
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008].
Disorder MIM:	610226
Disorder Html:	Seborrhea-like dermatitis with psoriasiform elements, 610227 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_024702.3	NP_078978.2	zinc finger protein 750
NM_024702.2	NP_078978.2	zinc finger protein 750

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ZNF750	NP_001075002.1
Rattus norvegicus (Norway rat)	Znf750	XP_006248020.1
Gallus gallus (chicken)	ZNF750	XP_004946140.1
Homo sapiens (human)	ZNF750	NP_078978.2
Mus musculus (house mouse)	Zfp750	NP_848878.1
Danio rerio (zebrafish)	znf750	NP_001017786.1
Xenopus tropicalis (tropical clawed frog)	znf750	NP_001004995.1
Pan troglodytes (chimpanzee)	ZNF750	XP_001169026.1
	ZNF750	XP_001113623.1
Canis lupus familiaris (dog)	ZNF750	XP_850463.2

Gene Ontology
Bibliography

Related articles in PubMed

ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma.
Otsuka R, Akutsu Y, Sakata H, Hanari N, Murakami K, Kano M, Toyozumi T, Takahashi M, Matsumoto Y, Sekino N, Yokoyama M, Okada K, Shiraishi T, Komatsu A, Iida K, Matsubara H
Oncology(2017 Dec)

ZNF750 Expression as a Novel Candidate Biomarker of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma.
Otsuka R, Akutsu Y, Sakata H, Hanari N, Murakami K, Kano M, Takahashi M, Matsumoto Y, Sekino N, Yokoyama M, Iida K, Matsubara H
Oncology93(3)197-203(2017)

Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.
Hao JJ, Lin DC, Dinh HQ, Mayakonda A, Jiang YY, Chang C, Jiang Y, Lu CC, Shi ZZ, Xu X, Zhang Y, Cai Y, Wang JW, Zhan QM, Wei WQ, Berman BP, Wang MR, Koeffler HP
Nature genetics48(12)1500-1507(2016 Dec)

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation.
Bin L, Deng L, Yang H, Zhu L, Wang X, Edwards MG, Richers B, Leung DY
PloS one11(12)e0167392(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ZNF750 expression predicts sensitivity to CRT and can be a biomarker that reliably predicts the response of ESCC to CRT.
Title: ZNF750 Expression as a Novel Candidate Biomarker of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma.

ZNF750 Mutation is associated with esophageal squamous cell carcinoma.
Title: Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.

ZNF750 thus controls differentiation in concert with RCOR1 and CTBP1/2 by acting with either KDM1A to repress progenitor genes or KLF4 to induce differentiation genes.
Title: ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.

Suggest no connection of ZNF750 variants with psoriasis or its subphenotypes.
Title: Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.

ZNF750 was specifically expressed in the epidermal suprabasal layers and its expression was augmented during differentiation, both in human skin and in-vitro, peaking in the granular layer.
Title: ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes.

The following ZNF750 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZNF750 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19619	NM_024702.3 Latest version!	Homo sapiens zinc finger protein 750 (ZNF750), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu19619	NM_024702.2	Homo sapiens zinc finger protein 750 (ZNF750), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZNF750 ( NM_024702.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078978.2 Homo sapiens zinc finger protein 750 (ZNF750), mRNA.

Price & Availability↑

CloneID	OHu19619
Clone ID Related Accession (Same CDS sequence)	NM_024702.3 , NM_024702.2
Accession Version	NM_024702.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	zinc finger protein 750
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA433713.1, BC109037.1, DA872185.1, CO245511.1, AK023903.1 and AI539029.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_024702.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK023903.1, BC109037.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000269394.4/ ENSP00000269394.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA 
AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT 
TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT 
CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT 
GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG 
AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG 
GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC 
CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT 
GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG 
ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC 
CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT 
AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA 
GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG 
CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC 
CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC 
ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA 
TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC 
CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG 
AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA 
ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG 
AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC 
ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC 
GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA 
AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC 
AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC 
GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA 
GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC 
GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC 
ACCCAGGCTC CGAGGCCTGC CTTCCCCGGT CGACCACGAG CTGCAGAACC TGCTGCTGCT 
GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG 
CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC 
GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG 
CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA 
CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT 
GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA 
GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC 
CGGGTGTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078978.2
CDS	279..2450
Translation	MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCPKSNSLDPKQTNQPDATAKPASSKSVANGLSAFDSKLQHSSAREDIKENLELQARGTHRCLGQKPALHRASPCKSPAPEAALGAQPALEGAARPSAFVPVGEHRLKGPDNAEAPETLALHNPTAKAVSFHTKSAFHTPGYPWKAGSPFLPPEFPHKISSTKGLGAISPYMHPTIPEYPPHFYTEHGLATIYSPYLLAGSSPECDAPLLSVYGTQDPRHFLPHPGPIPKHLAPSPATYDHYRFFQQYPSNLPIPYGFYRPESAFSSYGLRLPPVTGLTRDQSSHLLEEATLVYPASSPSRLNPSDPNRKHVEFESPIPEAKDSSKAGQRDTEGSKMSPRAGSAATGSPGRPSPTDFMQTSQTCEGLYDLSNKAASSALGRLYPPEQSLTAFRPVKKSTECLPAQAAETTAESPVSLNVVNGDPPAPTGSASLVSEAAPSSPDDSSGMGPLNLSKKSEINLAATHEPTYQGSPQAETASFSELQDLPLNLSVKDPCNTQAPRPAFPGRPRAAEPAAAVPQKTGTEGSEDGPSHPETKPGSLDGDGAPPTGPGEEAPDACAVDSSEEQKQTAAVALCQLAAYSPRNIRVGDGDAAAPEPACRQDTPTLSSMESQEAQCDLRPKGQKRTSLRDAGKSQQGAKKAKLQDTARVFTLRRRARVS

Target ORF information:

RefSeq Version	NM_024702.3
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 750 (ZNF750), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024702.3

ORF Insert Sequence:

ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA 
AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT 
TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT 
CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT 
GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG 
AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG 
GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC 
CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT 
GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG 
ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC 
CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT 
AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA 
GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG 
CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC 
CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC 
ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA 
TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC 
CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG 
AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA 
ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG 
AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC 
ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC 
GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA 
AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC 
AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC 
GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA 
GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC 
GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC 
ACCCAGGCTC CGAGGCCTGC CTTCCCCGGT CGACCACGAG CTGCAGAACC TGCTGCTGCT 
GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG 
CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC 
GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG 
CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA 
CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT 
GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA 
GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC 
CGGGTGTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZNF750 ( NM_024702.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_078978.2 Homo sapiens zinc finger protein 750 (ZNF750), mRNA.

Price & Availability↑

CloneID	OHu19619
Clone ID Related Accession (Same CDS sequence)	NM_024702.3 , NM_024702.2
Accession Version	NM_024702.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	zinc finger protein 750
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA433713.1, BC109037.1, DA872185.1, CO245511.1, AK023903.1 and AI539029.1. This sequence is a reference standard in the RefSeqGene project. On Aug 25, 2006 this sequence version replaced NM_024702.1. ##Evidence-Data-START## Transcript exon combination :: AK023903.1, BC109037.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150585 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA 
AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT 
TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT 
CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT 
GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG 
AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG 
GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC 
CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT 
GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG 
ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC 
CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT 
AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA 
GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG 
CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC 
CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC 
ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA 
TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC 
CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG 
AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA 
ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG 
AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC 
ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC 
GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA 
AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC 
AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC 
GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA 
GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC 
GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC 
ACCCAGGCTC CGAGGCCTGC CTTCCCCGGT CGACCACGAG CTGCAGAACC TGCTGCTGCT 
GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG 
CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC 
GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG 
CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA 
CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT 
GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA 
GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC 
CGGGTGTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078978.2
CDS	312..2483
Translation	MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCPKSNSLDPKQTNQPDATAKPASSKSVANGLSAFDSKLQHSSAREDIKENLELQARGTHRCLGQKPALHRASPCKSPAPEAALGAQPALEGAARPSAFVPVGEHRLKGPDNAEAPETLALHNPTAKAVSFHTKSAFHTPGYPWKAGSPFLPPEFPHKISSTKGLGAISPYMHPTIPEYPPHFYTEHGLATIYSPYLLAGSSPECDAPLLSVYGTQDPRHFLPHPGPIPKHLAPSPATYDHYRFFQQYPSNLPIPYGFYRPESAFSSYGLRLPPVTGLTRDQSSHLLEEATLVYPASSPSRLNPSDPNRKHVEFESPIPEAKDSSKAGQRDTEGSKMSPRAGSAATGSPGRPSPTDFMQTSQTCEGLYDLSNKAASSALGRLYPPEQSLTAFRPVKKSTECLPAQAAETTAESPVSLNVVNGDPPAPTGSASLVSEAAPSSPDDSSGMGPLNLSKKSEINLAATHEPTYQGSPQAETASFSELQDLPLNLSVKDPCNTQAPRPAFPGRPRAAEPAAAVPQKTGTEGSEDGPSHPETKPGSLDGDGAPPTGPGEEAPDACAVDSSEEQKQTAAVALCQLAAYSPRNIRVGDGDAAAPEPACRQDTPTLSSMESQEAQCDLRPKGQKRTSLRDAGKSQQGAKKAKLQDTARVFTLRRRARVS

Target ORF information:

RefSeq Version	NM_024702.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 750 (ZNF750), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024702.2

ORF Insert Sequence:

ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA 
AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT 
TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT 
CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT 
GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG 
AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG 
GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC 
CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT 
GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG 
ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC 
CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT 
AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA 
GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG 
CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC 
CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC 
ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA 
TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC 
CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG 
AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA 
ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG 
AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC 
ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC 
GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA 
AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC 
AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC 
GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA 
GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC 
GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC 
ACCCAGGCTC CGAGGCCTGC CTTCCCCGGT CGACCACGAG CTGCAGAACC TGCTGCTGCT 
GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG 
CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC 
GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG 
CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA 
CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT 
GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA 
GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC 
CGGGTGTCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma.
Oncology(2017 Dec)
Otsuka R,Akutsu Y,Sakata H,Hanari N,Murakami K,Kano M,Toyozumi T,Takahashi M,Matsumoto Y,Sekino N,Yokoyama M,Okada K,Shiraishi T,Komatsu A,Iida K,Matsubara H

ZNF750 Expression as a Novel Candidate Biomarker of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma.
Oncology93(3)197-203(2017)
Otsuka R,Akutsu Y,Sakata H,Hanari N,Murakami K,Kano M,Takahashi M,Matsumoto Y,Sekino N,Yokoyama M,Iida K,Matsubara H

Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.
Nature genetics48(12)1500-1507(2016 Dec)
Hao JJ,Lin DC,Dinh HQ,Mayakonda A,Jiang YY,Chang C,Jiang Y,Lu CC,Shi ZZ,Xu X,Zhang Y,Cai Y,Wang JW,Zhan QM,Wei WQ,Berman BP,Wang MR,Koeffler HP

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation.
PloS one11(12)e0167392(2016)
Bin L,Deng L,Yang H,Zhu L,Wang X,Edwards MG,Richers B,Leung DY

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ZNF750 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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