LMAN1L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LMAN1L
Entrez Gene ID	79748
Full Name	lectin, mannose binding 1 like
Synonyms	ERGIC-53L,ERGL
General protein information	Preferred Names lectin, mannose binding 1 like Names protein ERGIC-53-like ERGIC53-like protein LMAN1-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q24.1
Summary	This gene encodes a mannose-binding type 1 transmembrane protein that contains an N-terminal lectin-like carbohydrate recognition domain. The encoded protein is similar in structure to lectins found in leguminous plants. This lectin is thought to transport newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. [provided by RefSeq, Jan 2017].
Disorder MIM:	609548

mRNA and Protein(s)

mRNA	Protein	Name
NM_021819.2	NP_068591.2	protein ERGIC-53-like precursor
NM_021819.3	NP_068591.2	protein ERGIC-53-like precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LMAN1L	XP_003952751.1
Homo sapiens (human)	LMAN1L	NP_068591.2
Canis lupus familiaris (dog)	LMAN1L	XP_005638684.1
Mus musculus (house mouse)	Lman1l	NP_954692.2
	LOC709457	XP_001097975.2
Bos taurus (cattle)	LMAN1L	XP_002696725.3
Rattus norvegicus (Norway rat)	Lman1l	NP_001012483.1

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V, Cutillas PR, Balkwill FR, Hynes RO
Journal of proteome research16(8)3083-3091(2017 Aug)

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
Cornelis MC, Monda KL, Yu K, Paynter N, Azzato EM, Bennett SN, Berndt SI, Boerwinkle E, Chanock S, Chatterjee N, Couper D, Curhan G, Heiss G, Hu FB, Hunter DJ, Jacobs K, Jensen MK, Kraft P, Landi MT, Nettleton JA, Purdue MP, Rajaraman P, Rimm EB, Rose LM, Rothman N, Silverman D, Stolzenberg-Solomon R, Subar A, Yeager M, Chasman DI, van Dam RM, Caporaso NE
PLoS genetics7(4)e1002033(2011 Apr)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Genome-wide association study identifies eight loci associated with blood pressure.
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL, , Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, D?ring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syv?nen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, D?rr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, V?lker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, V?lzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB
Nature genetics41(6)666-76(2009 Jun)

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.
Nyfeler B, Reiterer V, Wendeler MW, Stefan E, Zhang B, Michnick SW, Hauri HP
The Journal of cell biology180(4)705-12(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Binding of ERGIC-53 to sugar is enhanced by its interaction with MCFD2, and defects in this interaction in factor V and VIII deeficient patients may be the cause for reduced secretion of factors V and VIII.
Title: The sugar-binding ability of ERGIC-53 is enhanced by its interaction with MCFD2.

The results reveal ERGIC-53 to be an intracellular transport receptor of alpha1-AT and provide direct evidence for active receptor-mediated ER export of a soluble secretory protein in higher eukaryotes
Title: Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.

ERGIC-53 provides a platform that receives micro(2)L(2) subunits from the BiP-dependent checkpoint, assisting polymerization. In this process, ERp44 couples thiol-dependent assembly and quality control.
Title: Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis.

The following LMAN1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LMAN1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03743	NM_021819.3 Latest version!	Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu03743	NM_021819.2	Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LMAN1L ( NM_021819.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_068591.2 Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.

Price & Availability↑

CloneID	OHu03743
Clone ID Related Accession (Same CDS sequence)	NM_021819.2 , NM_021819.3
Accession Version	NM_021819.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	protein ERGIC-53-like precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358724.1 and AF303398.1. This sequence is a reference standard in the RefSeqGene project. On Sep 15, 2005 this sequence version replaced NM_021819.1. ##Evidence-Data-START## Transcript exon combination :: AF303398.1, AK291819.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2150585 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCGG TCAGTGGTCC AGGTCCCTTA TTCTGCCTTC TCCTCCTGCT CCTGGACCCC 
CACAGCCCTG AGACGGGGTG TCCTCCTCTA CGCAGGTTTG AGTACAAGCT CAGCTTCAAA 
GGCCCAAGGC TGGCATTGCC TGGGGCTGGA ATACCCTTCT GGAGCCATCA TGGAGACGCC 
ATCCTGGGCC TGGAGGAAGT GCGGCTGACG CCATCCATGA GGAACCGGAG TGGCGCCGTG 
TGGAGCAGGG CCTCTGTCCC CTTCTCTGCC TGGGAAGTAG AGGTGCAGAT GAGGGTGACG 
GGACTGGGGC GCCGGGGAGC CCAGGGCATG GCCGTGTGGT ACACCCGGGG CAGGGGCCAT 
GTAGGCTCTG TCCTTGGGGG GCTGGCTTCG TGGGACGGCA TCGGGATCTT CTTTGACTCT 
CCGGCAGAGG ATACTCAGGA CAGTCCTGCC ATCCGTGTGC TGGCCAGCGA CGGGCACATC 
CCCTCTGAGC AGCCTGGGGA TGGAGCTAGC CAAGGGCTGG GCTCCTGTCA TTGGGACTTC 
CGGAACCGGC CACACCCCTT CAGAGCACGG ATCACCTACT GGGGGCAGAG GCTGCGCATG 
TCCTTGAACA GTGGCCTCAC TCCCAGTGAT CCAGGTGAGT TCTGTGTGGA TGTGGGGCCC 
CTGCTTTTGG TCCCTGGAGG TTTCTTTGGG GTCTCAGCAG CCACCGGCAC CCTGGCAGAT 
GATCATGATG TCCTGTCCTT CCTGACCTTC AGCCTGAGTG AGCCCAGCCC AGAGGTTCCC 
CCTCAGCCCT TCCTGGAGAT GCAGCAGCTC CGCCTGGCGA GGCAGCTGGA AGGGCTGTGG 
GCAAGGCTGG GCTTGGGCAC CAGGGAGGAT GTAACTCCAA AATCAGACTC TGAAGCTCAA 
GGAGAAGGGG AAAGGCTCTT TGACCTGGAG GAGACGCTGG GCAGACACCG CCGGATCCTG 
CAGGCTCTGC GGGGTCTCTC CAAGCAGCTG GCCCAGGCTG AGAGACAATG GAAGAAGCAG 
CTGGGGCCCC CAGGCCAAGC CAGGCCTGAC GGAGGCTGGG CCCTGGATGC TTCCTGCCAG 
ATTCCATCCA CCCCAGGGAG GGGTGGCCAC CTCTCCATGT CACTCAATAA GGACTCTGCC 
AAGGTCGGTG CCCTGCTCCA TGGACAGTGG ACTCTGCTCC AGGCCCTGCA AGAGATGAGG 
GATGCAGCTG TCCGCATGGC TGCAGAAGCC CAGGTCTCCT ACCTGCCTGT GGGCATTGAG 
CATCATTTCT TAGAGCTGGA CCACATCCTG GGCCTCCTGC AGGAGGAGCT TCGGGGCCCG 
GCGAAGGCAG CAGCCAAGGC CCCCCGCCCA CCTGGCCAGC CCCCAAGGGC CTCCTCGTGC 
CTGCAGCCTG GCATCTTCCT GTTCTACCTC CTCATTCAGA CTGTAGGCTT CTTCGGCTAC 
GTGCACTTCA GGCAGGAGCT GAACAAGAGC CTTCAGGAGT GTCTGTCCAC AGGCAGCCTT 
CCTCTGGGTC CTGCACCACA CACCCCCAGG GCCCTGGGGA TTCTGAGGAG GCAGCCTCTC 
CCTGCCAGCA TGCCTGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068591.2
CDS	3..1583
Translation	MPAVSGPGPLFCLLLLLLDPHSPETGCPPLRRFEYKLSFKGPRLALPGAGIPFWSHHGDAILGLEEVRLTPSMRNRSGAVWSRASVPFSAWEVEVQMRVTGLGRRGAQGMAVWYTRGRGHVGSVLGGLASWDGIGIFFDSPAEDTQDSPAIRVLASDGHIPSEQPGDGASQGLGSCHWDFRNRPHPFRARITYWGQRLRMSLNSGLTPSDPGEFCVDVGPLLLVPGGFFGVSAATGTLADDHDVLSFLTFSLSEPSPEVPPQPFLEMQQLRLARQLEGLWARLGLGTREDVTPKSDSEAQGEGERLFDLEETLGRHRRILQALRGLSKQLAQAERQWKKQLGPPGQARPDGGWALDASCQIPSTPGRGGHLSMSLNKDSAKVGALLHGQWTLLQALQEMRDAAVRMAAEAQVSYLPVGIEHHFLELDHILGLLQEELRGPAKAAAKAPRPPGQPPRASSCLQPGIFLFYLLIQTVGFFGYVHFRQELNKSLQECLSTGSLPLGPAPHTPRALGILRRQPLPASMPA

Target ORF information:

RefSeq Version	NM_021819.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021819.2

ORF Insert Sequence:

ATGCCGGCGG TCAGTGGTCC AGGTCCCTTA TTCTGCCTTC TCCTCCTGCT CCTGGACCCC 
CACAGCCCTG AGACGGGGTG TCCTCCTCTA CGCAGGTTTG AGTACAAGCT CAGCTTCAAA 
GGCCCAAGGC TGGCATTGCC TGGGGCTGGA ATACCCTTCT GGAGCCATCA TGGAGACGCC 
ATCCTGGGCC TGGAGGAAGT GCGGCTGACG CCATCCATGA GGAACCGGAG TGGCGCCGTG 
TGGAGCAGGG CCTCTGTCCC CTTCTCTGCC TGGGAAGTAG AGGTGCAGAT GAGGGTGACG 
GGACTGGGGC GCCGGGGAGC CCAGGGCATG GCCGTGTGGT ACACCCGGGG CAGGGGCCAT 
GTAGGCTCTG TCCTTGGGGG GCTGGCTTCG TGGGACGGCA TCGGGATCTT CTTTGACTCT 
CCGGCAGAGG ATACTCAGGA CAGTCCTGCC ATCCGTGTGC TGGCCAGCGA CGGGCACATC 
CCCTCTGAGC AGCCTGGGGA TGGAGCTAGC CAAGGGCTGG GCTCCTGTCA TTGGGACTTC 
CGGAACCGGC CACACCCCTT CAGAGCACGG ATCACCTACT GGGGGCAGAG GCTGCGCATG 
TCCTTGAACA GTGGCCTCAC TCCCAGTGAT CCAGGTGAGT TCTGTGTGGA TGTGGGGCCC 
CTGCTTTTGG TCCCTGGAGG TTTCTTTGGG GTCTCAGCAG CCACCGGCAC CCTGGCAGAT 
GATCATGATG TCCTGTCCTT CCTGACCTTC AGCCTGAGTG AGCCCAGCCC AGAGGTTCCC 
CCTCAGCCCT TCCTGGAGAT GCAGCAGCTC CGCCTGGCGA GGCAGCTGGA AGGGCTGTGG 
GCAAGGCTGG GCTTGGGCAC CAGGGAGGAT GTAACTCCAA AATCAGACTC TGAAGCTCAA 
GGAGAAGGGG AAAGGCTCTT TGACCTGGAG GAGACGCTGG GCAGACACCG CCGGATCCTG 
CAGGCTCTGC GGGGTCTCTC CAAGCAGCTG GCCCAGGCTG AGAGACAATG GAAGAAGCAG 
CTGGGGCCCC CAGGCCAAGC CAGGCCTGAC GGAGGCTGGG CCCTGGATGC TTCCTGCCAG 
ATTCCATCCA CCCCAGGGAG GGGTGGCCAC CTCTCCATGT CACTCAATAA GGACTCTGCC 
AAGGTCGGTG CCCTGCTCCA TGGACAGTGG ACTCTGCTCC AGGCCCTGCA AGAGATGAGG 
GATGCAGCTG TCCGCATGGC TGCAGAAGCC CAGGTCTCCT ACCTGCCTGT GGGCATTGAG 
CATCATTTCT TAGAGCTGGA CCACATCCTG GGCCTCCTGC AGGAGGAGCT TCGGGGCCCG 
GCGAAGGCAG CAGCCAAGGC CCCCCGCCCA CCTGGCCAGC CCCCAAGGGC CTCCTCGTGC 
CTGCAGCCTG GCATCTTCCT GTTCTACCTC CTCATTCAGA CTGTAGGCTT CTTCGGCTAC 
GTGCACTTCA GGCAGGAGCT GAACAAGAGC CTTCAGGAGT GTCTGTCCAC AGGCAGCCTT 
CCTCTGGGTC CTGCACCACA CACCCCCAGG GCCCTGGGGA TTCTGAGGAG GCAGCCTCTC 
CCTGCCAGCA TGCCTGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMAN1L ( NM_021819.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068591.2 Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.

Price & Availability↑

CloneID	OHu03743
Clone ID Related Accession (Same CDS sequence)	NM_021819.2 , NM_021819.3
Accession Version	NM_021819.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	protein ERGIC-53-like precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC091230.23, AY358724.1 and AF303398.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_021819.2. ##Evidence-Data-START## Transcript exon combination :: AK291819.1, AF303398.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2150585 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000309664.10/ ENSP00000310431.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCGG TCAGTGGTCC AGGTCCCTTA TTCTGCCTTC TCCTCCTGCT CCTGGACCCC 
CACAGCCCTG AGACGGGGTG TCCTCCTCTA CGCAGGTTTG AGTACAAGCT CAGCTTCAAA 
GGCCCAAGGC TGGCATTGCC TGGGGCTGGA ATACCCTTCT GGAGCCATCA TGGAGACGCC 
ATCCTGGGCC TGGAGGAAGT GCGGCTGACG CCATCCATGA GGAACCGGAG TGGCGCCGTG 
TGGAGCAGGG CCTCTGTCCC CTTCTCTGCC TGGGAAGTAG AGGTGCAGAT GAGGGTGACG 
GGACTGGGGC GCCGGGGAGC CCAGGGCATG GCCGTGTGGT ACACCCGGGG CAGGGGCCAT 
GTAGGCTCTG TCCTTGGGGG GCTGGCTTCG TGGGACGGCA TCGGGATCTT CTTTGACTCT 
CCGGCAGAGG ATACTCAGGA CAGTCCTGCC ATCCGTGTGC TGGCCAGCGA CGGGCACATC 
CCCTCTGAGC AGCCTGGGGA TGGAGCTAGC CAAGGGCTGG GCTCCTGTCA TTGGGACTTC 
CGGAACCGGC CACACCCCTT CAGAGCACGG ATCACCTACT GGGGGCAGAG GCTGCGCATG 
TCCTTGAACA GTGGCCTCAC TCCCAGTGAT CCAGGTGAGT TCTGTGTGGA TGTGGGGCCC 
CTGCTTTTGG TCCCTGGAGG TTTCTTTGGG GTCTCAGCAG CCACCGGCAC CCTGGCAGAT 
GATCATGATG TCCTGTCCTT CCTGACCTTC AGCCTGAGTG AGCCCAGCCC AGAGGTTCCC 
CCTCAGCCCT TCCTGGAGAT GCAGCAGCTC CGCCTGGCGA GGCAGCTGGA AGGGCTGTGG 
GCAAGGCTGG GCTTGGGCAC CAGGGAGGAT GTAACTCCAA AATCAGACTC TGAAGCTCAA 
GGAGAAGGGG AAAGGCTCTT TGACCTGGAG GAGACGCTGG GCAGACACCG CCGGATCCTG 
CAGGCTCTGC GGGGTCTCTC CAAGCAGCTG GCCCAGGCTG AGAGACAATG GAAGAAGCAG 
CTGGGGCCCC CAGGCCAAGC CAGGCCTGAC GGAGGCTGGG CCCTGGATGC TTCCTGCCAG 
ATTCCATCCA CCCCAGGGAG GGGTGGCCAC CTCTCCATGT CACTCAATAA GGACTCTGCC 
AAGGTCGGTG CCCTGCTCCA TGGACAGTGG ACTCTGCTCC AGGCCCTGCA AGAGATGAGG 
GATGCAGCTG TCCGCATGGC TGCAGAAGCC CAGGTCTCCT ACCTGCCTGT GGGCATTGAG 
CATCATTTCT TAGAGCTGGA CCACATCCTG GGCCTCCTGC AGGAGGAGCT TCGGGGCCCG 
GCGAAGGCAG CAGCCAAGGC CCCCCGCCCA CCTGGCCAGC CCCCAAGGGC CTCCTCGTGC 
CTGCAGCCTG GCATCTTCCT GTTCTACCTC CTCATTCAGA CTGTAGGCTT CTTCGGCTAC 
GTGCACTTCA GGCAGGAGCT GAACAAGAGC CTTCAGGAGT GTCTGTCCAC AGGCAGCCTT 
CCTCTGGGTC CTGCACCACA CACCCCCAGG GCCCTGGGGA TTCTGAGGAG GCAGCCTCTC 
CCTGCCAGCA TGCCTGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068591.2
CDS	21..1601
Translation	MPAVSGPGPLFCLLLLLLDPHSPETGCPPLRRFEYKLSFKGPRLALPGAGIPFWSHHGDAILGLEEVRLTPSMRNRSGAVWSRASVPFSAWEVEVQMRVTGLGRRGAQGMAVWYTRGRGHVGSVLGGLASWDGIGIFFDSPAEDTQDSPAIRVLASDGHIPSEQPGDGASQGLGSCHWDFRNRPHPFRARITYWGQRLRMSLNSGLTPSDPGEFCVDVGPLLLVPGGFFGVSAATGTLADDHDVLSFLTFSLSEPSPEVPPQPFLEMQQLRLARQLEGLWARLGLGTREDVTPKSDSEAQGEGERLFDLEETLGRHRRILQALRGLSKQLAQAERQWKKQLGPPGQARPDGGWALDASCQIPSTPGRGGHLSMSLNKDSAKVGALLHGQWTLLQALQEMRDAAVRMAAEAQVSYLPVGIEHHFLELDHILGLLQEELRGPAKAAAKAPRPPGQPPRASSCLQPGIFLFYLLIQTVGFFGYVHFRQELNKSLQECLSTGSLPLGPAPHTPRALGILRRQPLPASMPA

Target ORF information:

RefSeq Version	NM_021819.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lectin, mannose binding 1 like (LMAN1L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021819.3

ORF Insert Sequence:

ATGCCGGCGG TCAGTGGTCC AGGTCCCTTA TTCTGCCTTC TCCTCCTGCT CCTGGACCCC 
CACAGCCCTG AGACGGGGTG TCCTCCTCTA CGCAGGTTTG AGTACAAGCT CAGCTTCAAA 
GGCCCAAGGC TGGCATTGCC TGGGGCTGGA ATACCCTTCT GGAGCCATCA TGGAGACGCC 
ATCCTGGGCC TGGAGGAAGT GCGGCTGACG CCATCCATGA GGAACCGGAG TGGCGCCGTG 
TGGAGCAGGG CCTCTGTCCC CTTCTCTGCC TGGGAAGTAG AGGTGCAGAT GAGGGTGACG 
GGACTGGGGC GCCGGGGAGC CCAGGGCATG GCCGTGTGGT ACACCCGGGG CAGGGGCCAT 
GTAGGCTCTG TCCTTGGGGG GCTGGCTTCG TGGGACGGCA TCGGGATCTT CTTTGACTCT 
CCGGCAGAGG ATACTCAGGA CAGTCCTGCC ATCCGTGTGC TGGCCAGCGA CGGGCACATC 
CCCTCTGAGC AGCCTGGGGA TGGAGCTAGC CAAGGGCTGG GCTCCTGTCA TTGGGACTTC 
CGGAACCGGC CACACCCCTT CAGAGCACGG ATCACCTACT GGGGGCAGAG GCTGCGCATG 
TCCTTGAACA GTGGCCTCAC TCCCAGTGAT CCAGGTGAGT TCTGTGTGGA TGTGGGGCCC 
CTGCTTTTGG TCCCTGGAGG TTTCTTTGGG GTCTCAGCAG CCACCGGCAC CCTGGCAGAT 
GATCATGATG TCCTGTCCTT CCTGACCTTC AGCCTGAGTG AGCCCAGCCC AGAGGTTCCC 
CCTCAGCCCT TCCTGGAGAT GCAGCAGCTC CGCCTGGCGA GGCAGCTGGA AGGGCTGTGG 
GCAAGGCTGG GCTTGGGCAC CAGGGAGGAT GTAACTCCAA AATCAGACTC TGAAGCTCAA 
GGAGAAGGGG AAAGGCTCTT TGACCTGGAG GAGACGCTGG GCAGACACCG CCGGATCCTG 
CAGGCTCTGC GGGGTCTCTC CAAGCAGCTG GCCCAGGCTG AGAGACAATG GAAGAAGCAG 
CTGGGGCCCC CAGGCCAAGC CAGGCCTGAC GGAGGCTGGG CCCTGGATGC TTCCTGCCAG 
ATTCCATCCA CCCCAGGGAG GGGTGGCCAC CTCTCCATGT CACTCAATAA GGACTCTGCC 
AAGGTCGGTG CCCTGCTCCA TGGACAGTGG ACTCTGCTCC AGGCCCTGCA AGAGATGAGG 
GATGCAGCTG TCCGCATGGC TGCAGAAGCC CAGGTCTCCT ACCTGCCTGT GGGCATTGAG 
CATCATTTCT TAGAGCTGGA CCACATCCTG GGCCTCCTGC AGGAGGAGCT TCGGGGCCCG 
GCGAAGGCAG CAGCCAAGGC CCCCCGCCCA CCTGGCCAGC CCCCAAGGGC CTCCTCGTGC 
CTGCAGCCTG GCATCTTCCT GTTCTACCTC CTCATTCAGA CTGTAGGCTT CTTCGGCTAC 
GTGCACTTCA GGCAGGAGCT GAACAAGAGC CTTCAGGAGT GTCTGTCCAC AGGCAGCCTT 
CCTCTGGGTC CTGCACCACA CACCCCCAGG GCCCTGGGGA TTCTGAGGAG GCAGCCTCTC 
CCTGCCAGCA TGCCTGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Journal of proteome research16(8)3083-3091(2017 Aug)
Naba A,Pearce OMT,Del Rosario A,Ma D,Ding H,Rajeeve V,Cutillas PR,Balkwill FR,Hynes RO

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
PLoS genetics7(4)e1002033(2011 Apr)
Cornelis MC,Monda KL,Yu K,Paynter N,Azzato EM,Bennett SN,Berndt SI,Boerwinkle E,Chanock S,Chatterjee N,Couper D,Curhan G,Heiss G,Hu FB,Hunter DJ,Jacobs K,Jensen MK,Kraft P,Landi MT,Nettleton JA,Purdue MP,Rajaraman P,Rimm EB,Rose LM,Rothman N,Silverman D,Stolzenberg-Solomon R,Subar A,Yeager M,Chasman DI,van Dam RM,Caporaso NE

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Genome-wide association study identifies eight loci associated with blood pressure.
Nature genetics41(6)666-76(2009 Jun)
Newton-Cheh C,Johnson T,Gateva V,Tobin MD,Bochud M,Coin L,Najjar SS,Zhao JH,Heath SC,Eyheramendy S,Papadakis K,Voight BF,Scott LJ,Zhang F,Farrall M,Tanaka T,Wallace C,Chambers JC,Khaw KT,Nilsson P,van der Harst P,Polidoro S,Grobbee DE,Onland-Moret NC,Bots ML,Wain LV,Elliott KS,Teumer A,Luan J,Lucas G,Kuusisto J,Burton PR,Hadley D,McArdle WL,,Brown M,Dominiczak A,Newhouse SJ,Samani NJ,Webster J,Zeggini E,Beckmann JS,Bergmann S,Lim N,Song K,Vollenweider P,Waeber G,Waterworth DM,Yuan X,Groop L,Orho-Melander M,Allione A,Di Gregorio A,Guarrera S,Panico S,Ricceri F,Romanazzi V,Sacerdote C,Vineis P,Barroso I,Sandhu MS,Luben RN,Crawford GJ,Jousilahti P,Perola M,Boehnke M,Bonnycastle LL,Collins FS,Jackson AU,Mohlke KL,Stringham HM,Valle TT,Willer CJ,Bergman RN,Morken MA,D?ring A,Gieger C,Illig T,Meitinger T,Org E,Pfeufer A,Wichmann HE,Kathiresan S,Marrugat J,O'Donnell CJ,Schwartz SM,Siscovick DS,Subirana I,Freimer NB,Hartikainen AL,McCarthy MI,O'Reilly PF,Peltonen L,Pouta A,de Jong PE,Snieder H,van Gilst WH,Clarke R,Goel A,Hamsten A,Peden JF,Seedorf U,Syv?nen AC,Tognoni G,Lakatta EG,Sanna S,Scheet P,Schlessinger D,Scuteri A,D?rr M,Ernst F,Felix SB,Homuth G,Lorbeer R,Reffelmann T,Rettig R,V?lker U,Galan P,Gut IG,Hercberg S,Lathrop GM,Zelenika D,Deloukas P,Soranzo N,Williams FM,Zhai G,Salomaa V,Laakso M,Elosua R,Forouhi NG,V?lzke H,Uiterwaal CS,van der Schouw YT,Numans ME,Matullo G,Navis G,Berglund G,Bingham SA,Kooner JS,Connell JM,Bandinelli S,Ferrucci L,Watkins H,Spector TD,Tuomilehto J,Altshuler D,Strachan DP,Laan M,Meneton P,Wareham NJ,Uda M,Jarvelin MR,Mooser V,Melander O,Loos RJ,Elliott P,Abecasis GR,Caulfield M,Munroe PB

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.
The Journal of cell biology180(4)705-12(2008 Feb)
Nyfeler B,Reiterer V,Wendeler MW,Stefan E,Zhang B,Michnick SW,Hauri HP

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LMAN1L cDNA ORF clone, Homo sapiens(human)

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