E2F8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	E2F8
Entrez Gene ID	79733
Full Name	E2F transcription factor 8
Synonyms	E2F-8
General protein information	Preferred Names E2F transcription factor 8 Names transcription factor E2F8 E2F family member 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.1
Summary	This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
Disorder MIM:	612047

mRNA and Protein(s)

mRNA	Protein	Name
XM_011520367.1	XP_011518669.1	transcription factor E2F8 isoform X1
NM_001256371.1	NP_001243300.1	transcription factor E2F8
NM_001256372.1	NP_001243301.1	transcription factor E2F8
NM_024680.3	NP_078956.2	transcription factor E2F8
NM_024680.4	NP_078956.2	transcription factor E2F8

Pathways from BioSystems

Homologies

Homo sapiens (human)	E2F8	NP_001243300.1
	E2F8	XP_001095088.1
Bos taurus (cattle)	E2F8	NP_001178163.1
Pan troglodytes (chimpanzee)	E2F8	XP_508325.2
Gallus gallus (chicken)	E2F8	XP_420910.4
Mus musculus (house mouse)	E2f8	NP_001013386.2
Canis lupus familiaris (dog)	E2F8	XP_534087.2
Rattus norvegicus (Norway rat)	E2f8	XP_006229325.1
Danio rerio (zebrafish)	e2f8	XP_005168886.1
Xenopus tropicalis (tropical clawed frog)	e2f8	XP_002942881.1

Gene Ontology
Bibliography

Related articles in PubMed

E2F8 confers cisplatin resistance to ER+ breast cancer cells via transcriptionally activating MASTL.
Tian J, Lin Y, Yu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie92919-926(2017 Aug)

E2F8, a direct target of miR-144, promotes papillary thyroid cancer progression via regulating cell cycle.
Sun J, Shi R, Zhao S, Li X, Lu S, Bu H, Ma X, Su C
Journal of experimental & clinical cancer research : CR36(1)40(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study provides evidence that E2F8 functions as a proliferation-related oncogene in papillary thyroid cancer progression. Moreover, miR-144 appears to be a tumor suppressor through direct inhibition of E2F8.
Title: E2F8, a direct target of miR-144, promotes papillary thyroid cancer progression via regulating cell cycle.

Results showed that E2F8 is up-regulated in metastatic prostate cancer and associated with poor prognosis. These results indicate that E2F8 is a crucial transcription regulator controlling cell cycle and survival in prostate cancer cells.
Title: Geraniol suppresses prostate cancer growth through down-regulation of E2F8.

E2F8-mediated transcriptional repression is a critical tumor suppressor mechanism during postnatal liver development
Title: E2f8 mediates tumor suppression in postnatal liver development.

E2F8 is overexpressed in Lung Cancer and is required for the growth of LC cells. E2F8 knockdown reduced the expression of UHRF1. These findings implicate E2F8 as a novel therapeutic target for LC treatment.
Title: E2F8 as a Novel Therapeutic Target for Lung Cancer.

transcription factor E2F8 is involved in the polyploidization during mouse and human decidualization
Title: Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.

The following E2F8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the E2F8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04173	NM_001256371.1 Latest version!	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu04173	NM_024680.4 Latest version!	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu04173	NM_001256372.1 Latest version!	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu72061	XM_011520367.1 Latest version!	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu04173	NM_024680.3	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

E2F8 ( NM_001256371.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243300.1 Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04173
Clone ID Related Accession (Same CDS sequence)	NM_001256371.1 , NM_001256372.1 , NM_024680.3 , NM_024680.4
Accession Version	NM_001256371.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	transcription factor E2F8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA758300.1, AC009652.14 and BM972658.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK292688.1, BC126402.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243300.1
CDS	324..2927
Translation	MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH

Target ORF information:

RefSeq Version	NM_001256371.1
Organism	Homo sapiens(human)
Definition	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256371.1

ORF Insert Sequence:

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

E2F8 ( NM_001256372.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243301.1 Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04173
Clone ID Related Accession (Same CDS sequence)	NM_001256371.1 , NM_001256372.1 , NM_024680.3 , NM_024680.4
Accession Version	NM_001256372.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	transcription factor E2F8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX504614.1, AK292688.1, AC009652.14 and BM972658.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292688.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243301.1
CDS	269..2872
Translation	MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH

Target ORF information:

RefSeq Version	NM_001256372.1
Organism	Homo sapiens(human)
Definition	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256372.1

ORF Insert Sequence:

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

E2F8 ( NM_024680.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078956.2 Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04173
Clone ID Related Accession (Same CDS sequence)	NM_001256371.1 , NM_001256372.1 , NM_024680.3 , NM_024680.4
Accession Version	NM_024680.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	transcription factor E2F8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB959621.1, BX504614.1, BU164108.1, AK055206.1, AK026964.1, BC028244.1 and BM972658.1. On Jan 24, 2012 this sequence version replaced NM_024680.2. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC126402.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078956.2
CDS	523..3126
Translation	MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH

Target ORF information:

RefSeq Version	NM_024680.3
Organism	Homo sapiens(human)
Definition	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024680.3

ORF Insert Sequence:

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

E2F8 ( NM_024680.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078956.2 Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04173
Clone ID Related Accession (Same CDS sequence)	NM_001256371.1 , NM_001256372.1 , NM_024680.3 , NM_024680.4
Accession Version	NM_024680.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	transcription factor E2F8
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB959621.1, BX504614.1, BU164108.1, AK055206.1, AK026964.1, BC028244.1 and BM972658.1. On Nov 22, 2018 this sequence version replaced NM_024680.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC126402.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000250024.9/ ENSP00000250024.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078956.2
CDS	508..3111
Translation	MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH

Target ORF information:

RefSeq Version	NM_024680.4
Organism	Homo sapiens(human)
Definition	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024680.4

ORF Insert Sequence:

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT AATGTTGAAC GTCGACGCAT TTACGATATC 
GTGAACGTCC TAGAGAGTTT ACATATGGTG AGCCGCCTCG CCAAAAACAG GTACACTTGG 
CACGGGCGAC ACAATCTCAA CAAAACCCTT GGCACCTTGA AGAGCATCGG GGAGGAGAAT 
AAGTACGCCG AGCAGATTAT GATGATCAAA AAGAAAGAAT ATGAGCAAGA GTTTGACTTT 
ATTAAGAGTT ACAGTATAGA GGATCATATC ATCAAATCAA ACACTGGCCC AAATGGACAC 
CCAGACATGT GTTTTGTGGA ACTCCCTGGA GTGGAATTTC GGGCAGCTTC TGTAAACAGC 
CGCAAAGACA AGTCTTTAAG GGTAATGAGC CAGAAATTTG TGATGCTGTT TTTGGTGTCA 
ACGCCTCAGA TAGTAAGCCT AGAAGTTGCT GCCAAGATTT TAATTGGGGA GGACCATGTG 
GAAGATTTGG ATAAAAGCAA GTTTAAAACA AAAATTAGGA GGTTGTATGA TATAGCTAAT 
GTTCTGAGTA GCCTGGATCT TATCAAGAAA GTTCATGTTA CAGAGGAAAG AGGCCGAAAA 
CCAGCTTTCA AATGGACCGG CCCAGAAATC AGTCCAAATA CCAGTGGCTC CAGCCCAGTC 
ATTCATTTTA CTCCCTCTGA TTTGGAGGTG AGACGGTCTT CAAAAGAGAA CTGTGCCAAA 
AACCTCTTTT CCACACGTGG GAAACCAAAC TTTACTCGAC ACCCATCTCT TATCAAATTG 
GTAAAGAGTA TAGAAAGTGA TCGGAGAAAG ATAAATTCTG CGCCCAGTAG CCCTATCAAG 
ACCAACAAAG CTGAGAGTTC TCAGAATTCT GCACCCTTCC CAAGTAAAAT GGCTCAGCTC 
GCAGCTATTT GTAAAATGCA GTTAGAAGAG CAATCAAGTG AATCCAGACA GAAAGTGAAA 
GTACAGCTGG CAAGATCTGG ACCCTGCAAA CCAGTAGCCC CTCTGGACCC CCCAGTGAAT 
GCTGAGATGG AGCTGACAGC ACCGTCCCTC ATCCAGCCCC TGGGAATGGT TCCCCTGATC 
CCCAGCCCCT TGTCATCAGC AGTGCCCCTG ATCCTACCTC AGGCCCCTTC AGGCCCATCC 
TATGCCATCT ACCTGCAGCC CACTCAAGCC CACCAAAGTG TGACGCCACC CCAAGGCCTG 
AGCCCAACGG TGTGCACCAC CCACTCTTCT AAAGCTACTG GCTCAAAAGA CTCCACAGAT 
GCCACCACTG AGAAGGCAGC CAATGATACC TCAAAGGCCA GTGCCTCTAC CAGGCCTGGA 
AGCTTGCTGC CAGCACCAGA GAGGCAAGGG GCAAAGAGCC GAACCAGGGA GCCAGCTGGA 
GAAAGAGGCT CAAAGAGGGC AAGCATGCTC GAGGACAGTG GTTCCAAAAA GAAATTTAAA 
GAGGACCTAA AAGGACTTGA AAATGTCTCC GCAACCTTGT TCCCATCAGG ATACCTAATC 
CCTCTCACGC AGTGCTCATC CCTGGGGGCA GAGTCCATTT TGTCTGGTAA AGAAAACTCA 
AGTGCTCTTT CCCCAAACCA CAGGATTTAC AGCTCCCCAA TTGCAGGTGT TATTCCAGTG 
ACATCATCTG AACTCACTGC TGTTAATTTT CCCTCTTTTC ATGTAACACC GTTGAAGCTA 
ATGGTCTCAC CAACTTCCGT GGCAGCCGTA CCTGTCGGGA ACAGCCCGGC TCTCGCTTCA 
AGCCACCCTG TTCCCATCCA GAACCCAAGC TCAGCCATTG TAAACTTCAC CCTGCAGCAC 
CTGGGACTCA TCTCACCCAA TGTGCAGTTG TCTGCCAGCC CTGGGTCTGG AATCGTTCCT 
GTGTCTCCAA GAATAGAGTC TGTTAATGTC GCACCAGAAA ATGCAGGCAC TCAGCAAGGA 
AGGGCCACCA ACTATGACTC ACCAGTCCCA GGCCAGAGCC AGCCAAATGG ACAATCAGTT 
GCTGTGACAG GGGCACAACA GCCTGTTCCT GTGACACCCA AAGGGTCACA ATTAGTGGCC 
GAAAGTTTCT TCCGTACCCC AGGTGGACCC ACCAAGCCAA CCAGCTCATC CTGCATGGAT 
TTTGAGGGTG CTAATAAAAC CTCCTTAGGA ACTCTCTTTG TCCCACAGCG AAAACTGGAA 
GTCTCAACAG AGGATGTCCA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

E2F8 ( XM_011520367.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518669.1 Homo sapiens E2F transcription factor 8 (E2F8), transcript variant X1, mRNA.

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CloneID	OHu72061
Clone ID Related Accession (Same CDS sequence)	XM_011520367.1
Accession Version	XM_011520367.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2289bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transcription factor E2F8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT ACTTCTGTAA ACAGCCGCAA AGACAAGTCT 
TTAAGGGTAA TGAGCCAGAA ATTTGTGATG CTGTTTTTGG TGTCAACGCC TCAGATAGTA 
AGCCTAGAAG TTGCTGCCAA GATTTTAATT GGGGAGGACC ATGTGGAAGA TTTGGATAAA 
AGCAAGTTTA AAACAAAAAT TAGGAGGTTG TATGATATAG CTAATGTTCT GAGTAGCCTG 
GATCTTATCA AGAAAGTTCA TGTTACAGAG GAAAGAGGCC GAAAACCAGC TTTCAAATGG 
ACCGGCCCAG AAATCAGTCC AAATACCAGT GGCTCCAGCC CAGTCATTCA TTTTACTCCC 
TCTGATTTGG AGGTGAGACG GTCTTCAAAA GAGAACTGTG CCAAAAACCT CTTTTCCACA 
CGTGGGAAAC CAAACTTTAC TCGACACCCA TCTCTTATCA AATTGGTAAA GAGTATAGAA 
AGTGATCGGA GAAAGATAAA TTCTGCGCCC AGTAGCCCTA TCAAGACCAA CAAAGCTGAG 
AGTTCTCAGA ATTCTGCACC CTTCCCAAGT AAAATGGCTC AGCTCGCAGC TATTTGTAAA 
ATGCAGTTAG AAGAGCAATC AAGTGAATCC AGACAGAAAG TGAAAGTACA GCTGGCAAGA 
TCTGGACCCT GCAAACCAGT AGCCCCTCTG GACCCCCCAG TGAATGCTGA GATGGAGCTG 
ACAGCACCGT CCCTCATCCA GCCCCTGGGA ATGGTTCCCC TGATCCCCAG CCCCTTGTCA 
TCAGCAGTGC CCCTGATCCT ACCTCAGGCC CCTTCAGGCC CATCCTATGC CATCTACCTG 
CAGCCCACTC AAGCCCACCA AAGTGTGACG CCACCCCAAG GCCTGAGCCC AACGGTGTGC 
ACCACCCACT CTTCTAAAGC TACTGGCTCA AAAGACTCCA CAGATGCCAC CACTGAGAAG 
GCAGCCAATG ATACCTCAAA GGCCAGTGCC TCTACCAGGC CTGGAAGCTT GCTGCCAGCA 
CCAGAGAGGC AAGGGGCAAA GAGCCGAACC AGGGAGCCAG CTGGAGAAAG AGGCTCAAAG 
AGGGCAAGCA TGCTCGAGGA CAGTGGTTCC AAAAAGAAAT TTAAAGAGGA CCTAAAAGGA 
CTTGAAAATG TCTCCGCAAC CTTGTTCCCA TCAGGATACC TAATCCCTCT CACGCAGTGC 
TCATCCCTGG GGGCAGAGTC CATTTTGTCT GGTAAAGAAA ACTCAAGTGC TCTTTCCCCA 
AACCACAGGA TTTACAGCTC CCCAATTGCA GGTGTTATTC CAGTGACATC ATCTGAACTC 
ACTGCTGTTA ATTTTCCCTC TTTTCATGTA ACACCGTTGA AGCTAATGGT CTCACCAACT 
TCCGTGGCAG CCGTACCTGT CGGGAACAGC CCGGCTCTCG CTTCAAGCCA CCCTGTTCCC 
ATCCAGAACC CAAGCTCAGC CATTGTAAAC TTCACCCTGC AGCACCTGGG ACTCATCTCA 
CCCAATGTGC AGTTGTCTGC CAGCCCTGGG TCTGGAATCG TTCCTGTGTC TCCAAGAATA 
GAGTCTGTTA ATGTCGCACC AGAAAATGCA GGCACTCAGC AAGGAAGGGC CACCAACTAT 
GACTCACCAG TCCCAGGCCA GAGCCAGCCA AATGGACAAT CAGTTGCTGT GACAGGGGCA 
CAACAGCCTG TTCCTGTGAC ACCCAAAGGG TCACAATTAG TGGCCGAAAG TTTCTTCCGT 
ACCCCAGGTG GACCCACCAA GCCAACCAGC TCATCCTGCA TGGATTTTGA GGGTGCTAAT 
AAAACCTCCT TAGGAACTCT CTTTGTCCCA CAGCGAAAAC TGGAAGTCTC AACAGAGGAT 
GTCCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518669.1
CDS	525..2813
Translation	MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELTSVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH

Target ORF information:

RefSeq Version	XM_011520367.1
Organism	Homo sapiens(human)
Definition	Homo sapiens E2F transcription factor 8 (E2F8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520367.1

ORF Insert Sequence:

ATGGAGAACG AAAAGGAAAA TCTCTTTTGT GAGCCACATA AAAGGGGACT AATGAAAACA 
CCTCTGAAAG AATCCACCAC AGCAAATATC GTGTTGGCAG AGATCCAGCC TGACTTTGGC 
CCTTTAACCA CACCTACCAA GCCCAAGGAA GGCTCTCAGG GAGAGCCGTG GACACCGACA 
GCCAACCTGA AAATGCTCAT CAGTGCTGTG AGCCCTGAGA TCCGCAACAG AGATCAGAAA 
AGGGGTTTGT TTGACAACAG AAGTGGATTA CCTGAGGCCA AAGACTGTAT ACACGAACAC 
TTATCTGGAG ATGAATTTGA GAAATCCCAA CCAAGTCGAA AAGAGAAAAG TTTAGGATTA 
TTGTGTCATA AGTTCTTAGC ACGATATCCT AATTATCCCA ACCCTGCTGT GAATAATGAC 
ATCTGCCTTG ACGAAGTGGC AGAGGAACTT ACTTCTGTAA ACAGCCGCAA AGACAAGTCT 
TTAAGGGTAA TGAGCCAGAA ATTTGTGATG CTGTTTTTGG TGTCAACGCC TCAGATAGTA 
AGCCTAGAAG TTGCTGCCAA GATTTTAATT GGGGAGGACC ATGTGGAAGA TTTGGATAAA 
AGCAAGTTTA AAACAAAAAT TAGGAGGTTG TATGATATAG CTAATGTTCT GAGTAGCCTG 
GATCTTATCA AGAAAGTTCA TGTTACAGAG GAAAGAGGCC GAAAACCAGC TTTCAAATGG 
ACCGGCCCAG AAATCAGTCC AAATACCAGT GGCTCCAGCC CAGTCATTCA TTTTACTCCC 
TCTGATTTGG AGGTGAGACG GTCTTCAAAA GAGAACTGTG CCAAAAACCT CTTTTCCACA 
CGTGGGAAAC CAAACTTTAC TCGACACCCA TCTCTTATCA AATTGGTAAA GAGTATAGAA 
AGTGATCGGA GAAAGATAAA TTCTGCGCCC AGTAGCCCTA TCAAGACCAA CAAAGCTGAG 
AGTTCTCAGA ATTCTGCACC CTTCCCAAGT AAAATGGCTC AGCTCGCAGC TATTTGTAAA 
ATGCAGTTAG AAGAGCAATC AAGTGAATCC AGACAGAAAG TGAAAGTACA GCTGGCAAGA 
TCTGGACCCT GCAAACCAGT AGCCCCTCTG GACCCCCCAG TGAATGCTGA GATGGAGCTG 
ACAGCACCGT CCCTCATCCA GCCCCTGGGA ATGGTTCCCC TGATCCCCAG CCCCTTGTCA 
TCAGCAGTGC CCCTGATCCT ACCTCAGGCC CCTTCAGGCC CATCCTATGC CATCTACCTG 
CAGCCCACTC AAGCCCACCA AAGTGTGACG CCACCCCAAG GCCTGAGCCC AACGGTGTGC 
ACCACCCACT CTTCTAAAGC TACTGGCTCA AAAGACTCCA CAGATGCCAC CACTGAGAAG 
GCAGCCAATG ATACCTCAAA GGCCAGTGCC TCTACCAGGC CTGGAAGCTT GCTGCCAGCA 
CCAGAGAGGC AAGGGGCAAA GAGCCGAACC AGGGAGCCAG CTGGAGAAAG AGGCTCAAAG 
AGGGCAAGCA TGCTCGAGGA CAGTGGTTCC AAAAAGAAAT TTAAAGAGGA CCTAAAAGGA 
CTTGAAAATG TCTCCGCAAC CTTGTTCCCA TCAGGATACC TAATCCCTCT CACGCAGTGC 
TCATCCCTGG GGGCAGAGTC CATTTTGTCT GGTAAAGAAA ACTCAAGTGC TCTTTCCCCA 
AACCACAGGA TTTACAGCTC CCCAATTGCA GGTGTTATTC CAGTGACATC ATCTGAACTC 
ACTGCTGTTA ATTTTCCCTC TTTTCATGTA ACACCGTTGA AGCTAATGGT CTCACCAACT 
TCCGTGGCAG CCGTACCTGT CGGGAACAGC CCGGCTCTCG CTTCAAGCCA CCCTGTTCCC 
ATCCAGAACC CAAGCTCAGC CATTGTAAAC TTCACCCTGC AGCACCTGGG ACTCATCTCA 
CCCAATGTGC AGTTGTCTGC CAGCCCTGGG TCTGGAATCG TTCCTGTGTC TCCAAGAATA 
GAGTCTGTTA ATGTCGCACC AGAAAATGCA GGCACTCAGC AAGGAAGGGC CACCAACTAT 
GACTCACCAG TCCCAGGCCA GAGCCAGCCA AATGGACAAT CAGTTGCTGT GACAGGGGCA 
CAACAGCCTG TTCCTGTGAC ACCCAAAGGG TCACAATTAG TGGCCGAAAG TTTCTTCCGT 
ACCCCAGGTG GACCCACCAA GCCAACCAGC TCATCCTGCA TGGATTTTGA GGGTGCTAAT 
AAAACCTCCT TAGGAACTCT CTTTGTCCCA CAGCGAAAAC TGGAAGTCTC AACAGAGGAT 
GTCCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E2F8 confers cisplatin resistance to ER+ breast cancer cells via transcriptionally activating MASTL.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie92919-926(2017 Aug)
Tian J,Lin Y,Yu J

E2F8, a direct target of miR-144, promotes papillary thyroid cancer progression via regulating cell cycle.
Journal of experimental & clinical cancer research : CR36(1)40(2017 Mar)
Sun J,Shi R,Zhao S,Li X,Lu S,Bu H,Ma X,Su C

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E2F8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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