CHMP6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHMP6
Entrez Gene ID	79643
Full Name	charged multivesicular body protein 6
Synonyms	VPS20
General protein information	Preferred Names charged multivesicular body protein 6 Names charged multivesicular body protein 6 chromatin-modifying protein 6 hVps20 vacuolar protein sorting-associated protein 20
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family. Proteins in this family are part of the ESCRT-III (endosomal sorting complex required for transport III) which degrades surface receptors, and in biosynthesis of endosomes. [provided by RefSeq, Mar 2012].
Disorder MIM:	610901

mRNA and Protein(s)

mRNA	Protein	Name
NM_024591.4	NP_078867.2	charged multivesicular body protein 6
XM_005257668.1	XP_005257725.1	charged multivesicular body protein 6 isoform X1
NM_024591.5	NP_078867.2	charged multivesicular body protein 6

Pathways from BioSystems

Homologies

	LOC718353	XP_001110906.2
Bos taurus (cattle)	CHMP6	NP_001068925.1
Canis lupus familiaris (dog)	CHMP6	XP_005624072.1
Gallus gallus (chicken)	CHMP6	NP_001026700.1
Drosophila melanogaster (fruit fly)	Vps20	NP_726213.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006229	XP_316297.4
Arabidopsis thaliana (thale cress)	VPS20.2	NP_196488.1
Xenopus tropicalis (tropical clawed frog)	chmp6	NP_001096541.1
Pan troglodytes (chimpanzee)	CHMP6	XP_001152905.3
Rattus norvegicus (Norway rat)	Chmp6	NP_001099326.1
Homo sapiens (human)	CHMP6	NP_078867.2
Mus musculus (house mouse)	Chmp6	NP_001078967.1
Danio rerio (zebrafish)	chmp6b	NP_001003874.1
Caenorhabditis elegans (roundworm)	vps-20	NP_490762.1
Arabidopsis thaliana (thale cress)	VPS20.1	NP_568980.1
Oryza sativa (rice)	Os02g0596500	NP_001047322.1

Gene Ontology
Bibliography

Related articles in PubMed

The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation.
Schuh AL, Hanna M, Quinney K, Wang L, Sarkeshik A, Yates JR 3rd, Audhya A
The Biochemical journal466(3)625-37(2015 Mar)

Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death.
Goliand I, Nachmias D, Gershony O, Elia N
Molecular biology of the cell25(23)3740-8(2014 Nov)

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE, Hanson PI
eLife3(2014 May)

CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling.
Zheng ZY, Cheng CM, Fu XR, Chen LY, Xu L, Terrillon S, Wong ST, Bar-Sagi D, Songyang Z, Chang EC
Oncogene31(43)4630-8(2012 Oct)

Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C, Vermeiren E, Zimmermann P, David G
Nature cell biology14(7)677-85(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Purified VPS-20 exhibits an open extended conformation, irrespective of ESCRT-II binding.
Title: The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation.

Taken together, these data suggest an active role for ESCRT-II and CHMP6 in ESCRT-mediated abscission
Title: Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death.

silencing CHMP6 and VPS4A also blocked epidermal growth factor receptor (EGFR) recycling
Title: CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling.

Results describe the mapping of multivesicular bodies with the second winged helix domain of human ESCRT-II subunit VPS25 and the first helix of ESCRT-III subunit VPS20.
Title: Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis.

In this study, we found that overexpression of chromatin modifying protein 6 (CHMP6) induced cell death by a series of experiments.
Title: Overexpression of CHMP6 induces cellular oncosis and apoptosis in HeLa cells.

The following CHMP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHMP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09078	NM_024591.5 Latest version!	Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu50664	XM_005257668.1 Latest version!	Homo sapiens charged multivesicular body protein 6 (CHMP6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09078	NM_024591.4	Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHMP6 ( NM_024591.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078867.2 Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.

Price & Availability↑

CloneID	OHu09078
Clone ID Related Accession (Same CDS sequence)	NM_024591.4 , NM_024591.5
Accession Version	NM_024591.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-09
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP196406.1, AK292105.1 and AK223187.1. On Jun 5, 2008 this sequence version replaced NM_024591.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223187.1, SRR1163658.98428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG AAAACGTCCC TGTCAAGGCC AGGCCCAGGC AGGCGGAGCT GGTGGCAGCT 
TCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078867.2
CDS	79..684
Translation	MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS

Target ORF information:

RefSeq Version	NM_024591.4
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024591.4

ORF Insert Sequence:

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG AAAACGTCCC TGTCAAGGCC AGGCCCAGGC AGGCGGAGCT GGTGGCAGCT 
TCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP6 ( NM_024591.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_078867.2 Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.

Price & Availability↑

CloneID	OHu09078
Clone ID Related Accession (Same CDS sequence)	NM_024591.4 , NM_024591.5
Accession Version	NM_024591.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP196406.1, AK292105.1 and AK223187.1. On Nov 22, 2018 this sequence version replaced NM_024591.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.306289.1, SRR3476690.158974.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000325167.9/ ENSP00000317468.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG AAAACGTCCC TGTCAAGGCC AGGCCCAGGC AGGCGGAGCT GGTGGCAGCT 
TCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078867.2
CDS	79..684
Translation	MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS

Target ORF information:

RefSeq Version	NM_024591.5
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 6 (CHMP6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024591.5

ORF Insert Sequence:

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG AAAACGTCCC TGTCAAGGCC AGGCCCAGGC AGGCGGAGCT GGTGGCAGCT 
TCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP6 ( XM_005257668.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005257725.1 Homo sapiens charged multivesicular body protein 6 (CHMP6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu50664
Clone ID Related Accession (Same CDS sequence)	XM_005257668.1
Accession Version	XM_005257668.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG GTATTTCCAT GTTTGATTCT TTTGAATGGT TGGAATTCGC AGGAGAAAAG 
TGGATTCTAG AAGGGAACAA GACAGAATGC TCCCAGGCCT TCCTGGGCCG TGGGCAAGCC 
CTGCTGCCTG GCTGTTTGGC TTGGGGGCGT GCGTGCCTGG CCTTGGGGTT GGGCTTGGGT 
TTCCCAGGGG TTCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005257725.1
CDS	79..816
Translation	MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPGISMFDSFEWLEFAGEKWILEGNKTECSQAFLGRGQALLPGCLAWGRACLALGLGLGFPGVR

Target ORF information:

RefSeq Version	XM_005257668.1
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 6 (CHMP6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005257668.1

ORF Insert Sequence:

ATGGGTAACC TGTTCGGCCG CAAGAAGCAG AGCCGCGTCA CGGAGCAGGA CAAGGCCATC 
CTGCAACTGA AGCAGCAGCG GGACAAGCTG AGGCAGTACC AGAAGAGGAT CGCCCAGCAG 
CTGGAGCGCG AGCGCGCCCT GGCCCGGCAG CTGCTGCGGG ACGGCAGGAA GGAACGGGCC 
AAGCTGCTGC TCAAGAAGAA GCGATACCAG GAGCAGCTCC TGGACAGGAC GGAGAACCAG 
ATCAGCAGCC TGGAGGCCAT GGTTCAGAGT ATTGAGTTCA CCCAGATCGA AATGAAAGTG 
ATGGAGGGGC TGCAGTTTGG AAATGAGTGT CTGAACAAGA TGCACCAGGT GATGTCCATT 
GAAGAGGTGG AGAGGATCCT GGACGAGACG CAGGAGGCCG TGGAGTACCA GCGGCAAATA 
GACGAGCTCC TGGCAGGAAG CTTCACTCAG GAGGATGAAG ACGCCATCCT GGAGGAGCTG 
AGCGCAATCA CTCAGGAACA AATAGAGCTG CCAGAGGTTC CCTCCGAGCC CCTTCCTGAG 
AAGATCCCAG GTATTTCCAT GTTTGATTCT TTTGAATGGT TGGAATTCGC AGGAGAAAAG 
TGGATTCTAG AAGGGAACAA GACAGAATGC TCCCAGGCCT TCCTGGGCCG TGGGCAAGCC 
CTGCTGCCTG GCTGTTTGGC TTGGGGGCGT GCGTGCCTGG CCTTGGGGTT GGGCTTGGGT 
TTCCCAGGGG TTCGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation.
The Biochemical journal466(3)625-37(2015 Mar)
Schuh AL,Hanna M,Quinney K,Wang L,Sarkeshik A,Yates JR 3rd,Audhya A

Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death.
Molecular biology of the cell25(23)3740-8(2014 Nov)
Goliand I,Nachmias D,Gershony O,Elia N

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
eLife3(2014 May)
Cashikar AG,Shim S,Roth R,Maldazys MR,Heuser JE,Hanson PI

CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling.
Oncogene31(43)4630-8(2012 Oct)
Zheng ZY,Cheng CM,Fu XR,Chen LY,Xu L,Terrillon S,Wong ST,Bar-Sagi D,Songyang Z,Chang EC

Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
Nature cell biology14(7)677-85(2012 Jun)
Baietti MF,Zhang Z,Mortier E,Melchior A,Degeest G,Geeraerts A,Ivarsson Y,Depoortere F,Coomans C,Vermeiren E,Zimmermann P,David G

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CHMP6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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