Gene Symbol | CDC73 |
Entrez Gene ID | 79577 |
Full Name | cell division cycle 73 |
Synonyms | C1orf28,FIHP,HPTJT,HRPT1,HRPT2,HYX |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]. |
Disorder MIM: | |
Disorder Html: | Hyperparathyroidism-jaw tumor syndrome, 145001 (3); Hyperparathyroidism, familial primary, 145000 (3); Parathyroid adenoma with cystic changes, 145001 (3); Parathyroid carcinoma, 608266 (3) |