ALG8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALG8
Entrez Gene ID	79053
Full Name	ALG8, alpha-1,3-glucosyltransferase
Synonyms	CDG1H
General protein information	Preferred Names ALG8, alpha-1,3-glucosyltransferase Names probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase HUSSY-02 asparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like protein asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase) asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase) asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog asparagine-linked glycosylation protein 8 homolog dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase dolichyl-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichol alpha- 1->3-glucosyltransferase dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl-alpha-1,3-glucosyltransferase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q14.1
Summary	This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Disorder MIM:	608103
Disorder Html:	Congenital disorder of glycosylation, type Ih, 608104 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_024079.4	NP_076984.2	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform a
XM_005274247.3	XP_005274304.1	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X1
NM_001007027.2	NP_001007028.1	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform b
XM_017018274.1	XP_016873763.1	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X2
XM_011545252.2	XP_011543554.1	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X3
NM_024079.5	NP_076984.2	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform a

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ALG8	XP_003313272.1
Canis lupus familiaris (dog)	ALG8	XP_533998.2
Mus musculus (house mouse)	Alg8	NP_950200.2
Danio rerio (zebrafish)	alg8	NP_001017647.1
Drosophila melanogaster (fruit fly)	CG4542	NP_572355.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003928	XP_318380.5
Schizosaccharomyces pombe (fission yeast)	alg8	NP_594599.1
Saccharomyces cerevisiae (baker's yeast)	ALG8	NP_014710.1
Neurospora crassa	NCU00163	XP_956676.1
Arabidopsis thaliana (thale cress)	AT2G44660	NP_181994.5
Xenopus tropicalis (tropical clawed frog)	alg8	NP_001076820.1
Gallus gallus (chicken)	ALG8	XP_004938993.1
Kluyveromyces lactis	KLLA0F16621g	XP_455827.1
Eremothecium gossypii	AGOS_ADR210C	NP_984306.2
Homo sapiens (human)	ALG8	NP_076984.2
Rattus norvegicus (Norway rat)	Alg8	NP_001029299.1
Bos taurus (cattle)	ALG8	NP_001069593.1
Magnaporthe oryzae (rice blast fungus)	MGG_05686	XP_003710585.1
Oryza sativa (rice)	Os02g0688500	NP_001047779.1

Gene Ontology
Bibliography

Related articles in PubMed

Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Besse W, Dong K, Choi J, Punia S, Fedeles SV, Choi M, Gallagher AR, Huang EB, Gulati A, Knight J, Mane S, Tahvanainen E, Tahvanainen P, Sanna-Cherchi S, Lifton RP, Watnick T, Pei YP, Torres VE, Somlo S
The Journal of clinical investigation127(5)1772-1785(2017 May)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

ALG8-CDG: novel patients and review of the literature.
H?ck M, Wegleiter K, Ralser E, Kiechl-Kohlendorfer U, Scholl-B?rgi S, Fauth C, Steichen E, Pichler K, Lefeber DJ, Matthjis G, Keldermans L, Maurer K, Zschocke J, Karall D
Orphanet journal of rare diseases1073(2015 Jun)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

Wrinkled skin and fat pads in patients with ALG8-CDG: revisiting skin manifestations in congenital disorders of glycosylation.
Kouwenberg D, Gardeitchik T, Mohamed M, Lefeber DJ, Morava E
Pediatric dermatology31(1)e1-5(2014 Jan-Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

used whole exome sequencing in a discovery cohort of 102 unrelated patients who were excluded for mutations in the 2 most common polycystic liver disease genes, PRKCSH and SEC63, to identify heterozygous loss-of-function mutations in 3 additional genes, ALG8, GANAB, and SEC61B. Similarly to PRKCSH and SEC63, these genes encode proteins that are integral to the protein biogenesis pathway in the endoplasmic reticulum.
Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.

In ALG8-CDG, isoelectric focusing of transferrin in serum or plasma shows an abnormal sialotransferrin pattern. The diagnosis is confirmed by mutation analysis in ALG8; all patients reported so far had point mutations or small deletions
Title: ALG8-CDG: novel patients and review of the literature.

We reviewed the clinical features in all nine previously reported patients diagnosed with ALG8-disorder of glycosylation with a special focus on their skin signs.
Title: Wrinkled skin and fat pads in patients with ALG8-CDG: revisiting skin manifestations in congenital disorders of glycosylation.

Severe ALG8 congenital disorder of glycosylation(CDG-Ih) is associated with homozygosity for two novel missense mutations in exon 8 of ALG8
Title: Severe ALG8-CDG (CDG-Ih) associated with homozygosity for two novel missense mutations detected by exome sequencing of candidate genes.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following ALG8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALG8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18279	NM_024079.5 Latest version!	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu16269	NM_001007027.2 Latest version!	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu45515	XM_005274247.3 Latest version!	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu71738	XM_011545252.2 Latest version!	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu92495	XM_017018274.1 Latest version!	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu18279	NM_024079.4	Homo sapiens ALG8, alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALG8 ( NM_024079.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_076984.2 Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18279
Clone ID Related Accession (Same CDS sequence)	NM_024079.4 , NM_024079.5
Accession Version	NM_024079.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK098614.1 and DB362104.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_024079.4. Transcript Variant: This variant (1) represents the shorter transcript, but encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001133.2, SRR5189655.70914.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299626.10/ ENSP00000299626.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA AAAGAAAAAC CTCTTTTTAA TTGGATGGAA 
ACTTTCTACC TGCTTGGCCT GGGGCCTCTG GAAGTCTGCT GTGAATTTGT ATTCCCTTTC 
ACCTCCTGGA AGGTGAAGTA CCCCTTCATC CCTTTGTTAC TAACCTCAGT GTATTGTGCA 
GTAGGCATCA CATATGCTTG GTTCAAACTG TATGTTTCAG TATTGATTGA CTCTGCTATT 
GGCAAGACAA AGAAACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076984.2
CDS	39..1619
Translation	MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ

Target ORF information:

RefSeq Version	NM_024079.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024079.5

ORF Insert Sequence:

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA AAAGAAAAAC CTCTTTTTAA TTGGATGGAA 
ACTTTCTACC TGCTTGGCCT GGGGCCTCTG GAAGTCTGCT GTGAATTTGT ATTCCCTTTC 
ACCTCCTGGA AGGTGAAGTA CCCCTTCATC CCTTTGTTAC TAACCTCAGT GTATTGTGCA 
GTAGGCATCA CATATGCTTG GTTCAAACTG TATGTTTCAG TATTGATTGA CTCTGCTATT 
GGCAAGACAA AGAAACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG8 ( NM_001007027.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001007028.1 Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16269
Clone ID Related Accession (Same CDS sequence)	NM_001007027.2
Accession Version	NM_001007027.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK098614.1, AA375954.1 and DB362104.1. On Apr 13, 2006 this sequence version replaced NM_001007027.1. Transcript Variant: This variant (2) contains an additional segment in the coding region compared to variant 1. The resulting isoform (b) contains a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.216493.1, SRR1803615.88400.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA CGGAGTTTCA CCCTTGTTGC CCAGGCTGGA 
GTGCAATGGC ACGATCTCAG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007028.1
CDS	66..1469
Translation	MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRRSFTLVAQAGVQWHDLS

Target ORF information:

RefSeq Version	NM_001007027.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007027.2

ORF Insert Sequence:

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA CGGAGTTTCA CCCTTGTTGC CCAGGCTGGA 
GTGCAATGGC ACGATCTCAG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG8 ( NM_024079.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_076984.2 Homo sapiens ALG8, alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18279
Clone ID Related Accession (Same CDS sequence)	NM_024079.4 , NM_024079.5
Accession Version	NM_024079.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK098614.1 and DB362104.1. This sequence is a reference standard in the RefSeqGene project. On Apr 13, 2006 this sequence version replaced NM_024079.3. Transcript Variant: This variant (1) represents the shorter transcript, but encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK098614.1, SRR1163658.55896.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA AAAGAAAAAC CTCTTTTTAA TTGGATGGAA 
ACTTTCTACC TGCTTGGCCT GGGGCCTCTG GAAGTCTGCT GTGAATTTGT ATTCCCTTTC 
ACCTCCTGGA AGGTGAAGTA CCCCTTCATC CCTTTGTTAC TAACCTCAGT GTATTGTGCA 
GTAGGCATCA CATATGCTTG GTTCAAACTG TATGTTTCAG TATTGATTGA CTCTGCTATT 
GGCAAGACAA AGAAACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076984.2
CDS	66..1646
Translation	MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ

Target ORF information:

RefSeq Version	NM_024079.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8, alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024079.4

ORF Insert Sequence:

ATGGCGGCGC TCACAATTGC CACGGGTACT GGCAATTGGT TTTCGGCTTT GGCGCTCGGG 
GTGACTCTTC TCAAATGCCT TCTCATCCCC ACATACCATT CCACAGATTT TGAAGTACAC 
CGAAACTGGC TTGCTATCAC TCACAGTTTG CCAATATCAC AGTGGTATTA TGAGGCAACT 
TCAGAGTGGA CGTTGGATTA CCCCCCTTTC TTTGCATGGT TTGAGTATAT CCTGTCACAT 
GTTGCCAAAT ATTTTGATCA AGAAATGCTG AATGTCCATA ATTTGAATTA CTCCAGCTCA 
AGGACCTTAC TTTTCCAGAG ATTTTCCGTC ATCTTTATGG ATGTACTCTT TGTGTATGCT 
GTCCGTGAGT GCTGTAAATG CATTGATGGA AAAAAAGTGG GTAAAGAACT TACAGAAAAG 
CCAAAATTTA TTCTGTCGGT ATTACTTCTG TGGAACTTCG GGTTATTAAT TGTGGACCAT 
ATTCATTTTC AGTACAATGG CTTTTTATTT GGATTAATGC TACTCTCCAT TGCACGATTA 
TTTCAGAAAA GGCATATGGA AGGAGCATTT CTCTTTGCTG TTCTCCTACA TTTCAAGCAT 
ATCTACCTCT ATGTAGCACC AGCTTATGGT GTATATCTGC TGCGATCCTA CTGTTTCACT 
GCAAATAAAC CAGATGGGTC TATTCGATGG AAGAGTTTCA GCTTTGTTCG TGTTATTTCC 
CTGGGACTGG TTGTTTTCTT AGTTTCTGCT CTTTCATTGG GTCCTTTCCT GGCCTTGAAT 
CAGCTGCCTC AAGTCTTTTC CCGACTCTTT CCTTTCAAGA GGGGCCTCTG TCATGCATAT 
TGGGCTCCAA ACTTCTGGGC TTTGTACAAT GCTTTGGACA AAGTGCTGTC TGTCATCGGT 
TTGAAATTGA AATTTCTTGA TCCCAACAAT ATTCCCAAGG CCTCAATGAC AAGTGGTTTG 
GTTCAGCAGT TCCAACACAC AGTCCTTCCC TCAGTGACTC CCTTGGCAAC CCTCATCTGC 
ACACTGATTG CCATATTGCC CTCTATTTTC TGTCTTTGGT TTAAACCCCA AGGGCCCAGA 
GGCTTTCTCC GATGTCTAAC TCTTTGTGCC TTGAGCTCCT TTATGTTTGG GTGGCATGTT 
CATGAAAAAG CCATACTTCT AGCAATTCTC CCAATGAGCC TTTTGTCTGT GGGAAAAGCA 
GGAGACGCTT CGATTTTTCT GATTCTGACC ACAACAGGAC ATTATTCCCT CTTTCCTCTG 
CTCTTCACTG CACCAGAACT TCCCATTAAA ATCTTACTCA TGTTACTATT CACCATATAT 
AGTATTTCGT CACTGAAGAC TTTATTCAGA AAAGAAAAAC CTCTTTTTAA TTGGATGGAA 
ACTTTCTACC TGCTTGGCCT GGGGCCTCTG GAAGTCTGCT GTGAATTTGT ATTCCCTTTC 
ACCTCCTGGA AGGTGAAGTA CCCCTTCATC CCTTTGTTAC TAACCTCAGT GTATTGTGCA 
GTAGGCATCA CATATGCTTG GTTCAAACTG TATGTTTCAG TATTGATTGA CTCTGCTATT 
GGCAAGACAA AGAAACAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG8 ( XM_005274247.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005274304.1 Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu45515
Clone ID Related Accession (Same CDS sequence)	XM_005274247.3
Accession Version	XM_005274247.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005274247.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG GGCCAAGACT GAAAGCGTGG AAACCAAGAA GCAACCATGA AATGGTGGTG 
TGTATACACC ATTCCACAGA TTTTGAAGTA CACCGAAACT GGCTTGCTAT CACTCACAGT 
TTGCCAATAT CACAGTGGTA TTATGAGGCA ACTTCAGAGT GGACGTTGGA TTACCCCCCT 
TTCTTTGCAT GGTTTGAGTA TATCCTGTCA CATGTTGCCA AATATTTTGA TCAAGAAATG 
CTGAATGTCC ATAATTTGAA TTACTCCAGC TCAAGGACCT TACTTTTCCA GAGATTTTCC 
GTCATCTTTA TGGATGTACT CTTTGTGTAT GCTGTCCGTG AGTGCTGTAA ATGCATTGAT 
GGAAAAAAAG TGGGTAAAGA ACTTACAGAA AAGCCAAAAT TTATTCTGTC GGTATTACTT 
CTGTGGAACT TCGGGTTATT AATTGTGGAC CATATTCATT TTCAGTACAA TGGCTTTTTA 
TTTGGATTAA TGCTACTCTC CATTGCACGA TTATTTCAGA AAAGGCATAT GGAAGGAGCA 
TTTCTCTTTG CTGTTCTCCT ACATTTCAAG CATATCTACC TCTATGTAGC ACCAGCTTAT 
GGTGTATATC TGCTGCGATC CTACTGTTTC ACTGCAAATA AACCAGATGG GTCTATTCGA 
TGGAAGAGTT TCAGCTTTGT TCGTGTTATT TCCCTGGGAC TGGTTGTTTT CTTAGTTTCT 
GCTCTTTCAT TGGGTCCTTT CCTGGCCTTG AATCAGCTGC CTCAAGTCTT TTCCCGACTC 
TTTCCTTTCA AGAGGGGCCT CTGTCATGCA TATTGGGCTC CAAACTTCTG GGCTTTGTAC 
AATGCTTTGG ACAAAGTGCT GTCTGTCATC GGTTTGAAAT TGAAATTTCT TGATCCCAAC 
AATATTCCCA AGGCCTCAAT GACAAGTGGT TTGGTTCAGC AGTTCCAACA CACAGTCCTT 
CCCTCAGTGA CTCCCTTGGC AACCCTCATC TGCACACTGA TTGCCATATT GCCCTCTATT 
TTCTGTCTTT GGTTTAAACC CCAAGGGCCC AGAGGCTTTC TCCGATGTCT AACTCTTTGT 
GCCTTGAGCT CCTTTATGTT TGGGTGGCAT GTTCATGAAA AAGCCATACT TCTAGCAATT 
CTCCCAATGA GCCTTTTGTC TGTGGGAAAA GCAGGAGACG CTTCGATTTT TCTGATTCTG 
ACCACAACAG GACATTATTC CCTCTTTCCT CTGCTCTTCA CTGCACCAGA ACTTCCCATT 
AAAATCTTAC TCATGTTACT ATTCACCATA TATAGTATTT CGTCACTGAA GACTTTATTC 
AGAAAAGAAA AACCTCTTTT TAATTGGATG GAAACTTTCT ACCTGCTTGG CCTGGGGCCT 
CTGGAAGTCT GCTGTGAATT TGTATTCCCT TTCACCTCCT GGAAGGTGAA GTACCCCTTC 
ATCCCTTTGT TACTAACCTC AGTGTATTGT GCAGTAGGCA TCACATATGC TTGGTTCAAA 
CTGTATGTTT CAGTATTGAT TGACTCTGCT ATTGGCAAGA CAAAGAAACA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005274304.1
CDS	854..2407
Translation	MDVGPRLKAWKPRSNHEMVVCIHHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ

Target ORF information:

RefSeq Version	XM_005274247.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005274247.3

ORF Insert Sequence:

ATGGATGTAG GGCCAAGACT GAAAGCGTGG AAACCAAGAA GCAACCATGA AATGGTGGTG 
TGTATACACC ATTCCACAGA TTTTGAAGTA CACCGAAACT GGCTTGCTAT CACTCACAGT 
TTGCCAATAT CACAGTGGTA TTATGAGGCA ACTTCAGAGT GGACGTTGGA TTACCCCCCT 
TTCTTTGCAT GGTTTGAGTA TATCCTGTCA CATGTTGCCA AATATTTTGA TCAAGAAATG 
CTGAATGTCC ATAATTTGAA TTACTCCAGC TCAAGGACCT TACTTTTCCA GAGATTTTCC 
GTCATCTTTA TGGATGTACT CTTTGTGTAT GCTGTCCGTG AGTGCTGTAA ATGCATTGAT 
GGAAAAAAAG TGGGTAAAGA ACTTACAGAA AAGCCAAAAT TTATTCTGTC GGTATTACTT 
CTGTGGAACT TCGGGTTATT AATTGTGGAC CATATTCATT TTCAGTACAA TGGCTTTTTA 
TTTGGATTAA TGCTACTCTC CATTGCACGA TTATTTCAGA AAAGGCATAT GGAAGGAGCA 
TTTCTCTTTG CTGTTCTCCT ACATTTCAAG CATATCTACC TCTATGTAGC ACCAGCTTAT 
GGTGTATATC TGCTGCGATC CTACTGTTTC ACTGCAAATA AACCAGATGG GTCTATTCGA 
TGGAAGAGTT TCAGCTTTGT TCGTGTTATT TCCCTGGGAC TGGTTGTTTT CTTAGTTTCT 
GCTCTTTCAT TGGGTCCTTT CCTGGCCTTG AATCAGCTGC CTCAAGTCTT TTCCCGACTC 
TTTCCTTTCA AGAGGGGCCT CTGTCATGCA TATTGGGCTC CAAACTTCTG GGCTTTGTAC 
AATGCTTTGG ACAAAGTGCT GTCTGTCATC GGTTTGAAAT TGAAATTTCT TGATCCCAAC 
AATATTCCCA AGGCCTCAAT GACAAGTGGT TTGGTTCAGC AGTTCCAACA CACAGTCCTT 
CCCTCAGTGA CTCCCTTGGC AACCCTCATC TGCACACTGA TTGCCATATT GCCCTCTATT 
TTCTGTCTTT GGTTTAAACC CCAAGGGCCC AGAGGCTTTC TCCGATGTCT AACTCTTTGT 
GCCTTGAGCT CCTTTATGTT TGGGTGGCAT GTTCATGAAA AAGCCATACT TCTAGCAATT 
CTCCCAATGA GCCTTTTGTC TGTGGGAAAA GCAGGAGACG CTTCGATTTT TCTGATTCTG 
ACCACAACAG GACATTATTC CCTCTTTCCT CTGCTCTTCA CTGCACCAGA ACTTCCCATT 
AAAATCTTAC TCATGTTACT ATTCACCATA TATAGTATTT CGTCACTGAA GACTTTATTC 
AGAAAAGAAA AACCTCTTTT TAATTGGATG GAAACTTTCT ACCTGCTTGG CCTGGGGCCT 
CTGGAAGTCT GCTGTGAATT TGTATTCCCT TTCACCTCCT GGAAGGTGAA GTACCCCTTC 
ATCCCTTTGT TACTAACCTC AGTGTATTGT GCAGTAGGCA TCACATATGC TTGGTTCAAA 
CTGTATGTTT CAGTATTGAT TGACTCTGCT ATTGGCAAGA CAAAGAAACA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG8 ( XM_011545252.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543554.1 Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu71738
Clone ID Related Accession (Same CDS sequence)	XM_011545252.2
Accession Version	XM_011545252.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545252.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAATG TCCATAATTT GAATTACTCC AGCTCAAGGA CCTTACTTTT CCAGAGATTT 
TCCGTCATCT TTATGGATGT ACTCTTTGTG TATGCTGTCC GTGAGTGCTG TAAATGCATT 
GATGGAAAAA AAGTGGGTAA AGAACTTACA GAAAAGCCAA AATTTATTCT GTCGGTATTA 
CTTCTGTGGA ACTTCGGGTT ATTAATTGTG GACCATATTC ATTTTCAGTA CAATGGCTTT 
TTATTTGGAT TAATGCTACT CTCCATTGCA CGATTATTTC AGAAAAGGCA TATGGAAGGA 
GCATTTCTCT TTGCTGTTCT CCTACATTTC AAGCATATCT ACCTCTATGT AGCACCAGCT 
TATGGTGTAT ATCTGCTGCG ATCCTACTGT TTCACTGCAA ATAAACCAGA TGGGTCTATT 
CGATGGAAGA GTTTCAGCTT TGTTCGTGTT ATTTCCCTGG GACTGGTTGT TTTCTTAGTT 
TCTGCTCTTT CATTGGGTCC TTTCCTGGCC TTGAATCAGC TGCCTCAAGT CTTTTCCCGA 
CTCTTTCCTT TCAAGAGGGG CCTCTGTCAT GCATATTGGG CTCCAAACTT CTGGGCTTTG 
TACAATGCTT TGGACAAAGT GCTGTCTGTC ATCGGTTTGA AATTGAAATT TCTTGATCCC 
AACAATATTC CCAAGGCCTC AATGACAAGT GGTTTGGTTC AGCAGTTCCA ACACACAGTC 
CTTCCCTCAG TGACTCCCTT GGCAACCCTC ATCTGCACAC TGATTGCCAT ATTGCCCTCT 
ATTTTCTGTC TTTGGTTTAA ACCCCAAGGG CCCAGAGGCT TTCTCCGATG TCTAACTCTT 
TGTGCCTTGA GCTCCTTTAT GTTTGGGTGG CATGTTCATG AAAAAGCCAT ACTTCTAGCA 
ATTCTCCCAA TGAGCCTTTT GTCTGTGGGA AAAGCAGGAG ACGCTTCGAT TTTTCTGATT 
CTGACCACAA CAGGACATTA TTCCCTCTTT CCTCTGCTCT TCACTGCACC AGAACTTCCC 
ATTAAAATCT TACTCATGTT ACTATTCACC ATATATAGTA TTTCGTCACT GAAGACTTTA 
TTCAGAAAAG AAAAACCTCT TTTTAATTGG ATGGAAACTT TCTACCTGCT TGGCCTGGGG 
CCTCTGGAAG TCTGCTGTGA ATTTGTATTC CCTTTCACCT CCTGGAAGGT GAAGTACCCC 
TTCATCCCTT TGTTACTAAC CTCAGTGTAT TGTGCAGTAG GCATCACATA TGCTTGGTTC 
AAACTGTATG TTTCAGTATT GATTGACTCT GCTATTGGCA AGACAAAGAA ACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543554.1
CDS	340..1656
Translation	MLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ

Target ORF information:

RefSeq Version	XM_011545252.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545252.2

ORF Insert Sequence:

ATGCTGAATG TCCATAATTT GAATTACTCC AGCTCAAGGA CCTTACTTTT CCAGAGATTT 
TCCGTCATCT TTATGGATGT ACTCTTTGTG TATGCTGTCC GTGAGTGCTG TAAATGCATT 
GATGGAAAAA AAGTGGGTAA AGAACTTACA GAAAAGCCAA AATTTATTCT GTCGGTATTA 
CTTCTGTGGA ACTTCGGGTT ATTAATTGTG GACCATATTC ATTTTCAGTA CAATGGCTTT 
TTATTTGGAT TAATGCTACT CTCCATTGCA CGATTATTTC AGAAAAGGCA TATGGAAGGA 
GCATTTCTCT TTGCTGTTCT CCTACATTTC AAGCATATCT ACCTCTATGT AGCACCAGCT 
TATGGTGTAT ATCTGCTGCG ATCCTACTGT TTCACTGCAA ATAAACCAGA TGGGTCTATT 
CGATGGAAGA GTTTCAGCTT TGTTCGTGTT ATTTCCCTGG GACTGGTTGT TTTCTTAGTT 
TCTGCTCTTT CATTGGGTCC TTTCCTGGCC TTGAATCAGC TGCCTCAAGT CTTTTCCCGA 
CTCTTTCCTT TCAAGAGGGG CCTCTGTCAT GCATATTGGG CTCCAAACTT CTGGGCTTTG 
TACAATGCTT TGGACAAAGT GCTGTCTGTC ATCGGTTTGA AATTGAAATT TCTTGATCCC 
AACAATATTC CCAAGGCCTC AATGACAAGT GGTTTGGTTC AGCAGTTCCA ACACACAGTC 
CTTCCCTCAG TGACTCCCTT GGCAACCCTC ATCTGCACAC TGATTGCCAT ATTGCCCTCT 
ATTTTCTGTC TTTGGTTTAA ACCCCAAGGG CCCAGAGGCT TTCTCCGATG TCTAACTCTT 
TGTGCCTTGA GCTCCTTTAT GTTTGGGTGG CATGTTCATG AAAAAGCCAT ACTTCTAGCA 
ATTCTCCCAA TGAGCCTTTT GTCTGTGGGA AAAGCAGGAG ACGCTTCGAT TTTTCTGATT 
CTGACCACAA CAGGACATTA TTCCCTCTTT CCTCTGCTCT TCACTGCACC AGAACTTCCC 
ATTAAAATCT TACTCATGTT ACTATTCACC ATATATAGTA TTTCGTCACT GAAGACTTTA 
TTCAGAAAAG AAAAACCTCT TTTTAATTGG ATGGAAACTT TCTACCTGCT TGGCCTGGGG 
CCTCTGGAAG TCTGCTGTGA ATTTGTATTC CCTTTCACCT CCTGGAAGGT GAAGTACCCC 
TTCATCCCTT TGTTACTAAC CTCAGTGTAT TGTGCAGTAG GCATCACATA TGCTTGGTTC 
AAACTGTATG TTTCAGTATT GATTGACTCT GCTATTGGCA AGACAAAGAA ACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG8 ( XM_017018274.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873763.1 Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu92495
Clone ID Related Accession (Same CDS sequence)	XM_017018274.1
Accession Version	XM_017018274.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG GGCCAAGACT GAAAGCGTGG AAACCAAGAA GCAACCATGA AATGGTGGTG 
TGTATACACC ATTCCACAGA TTTTGAAGTA CACCGAAACT GGCTTGCTAT CACTCACAGT 
TTGCCAATAT CACAGTGGTA TTATGAGGCA ACTTCAGAGT GGACGTTGGA TTACCCCCCT 
TTCTTTGCAT GGTTTGAGTA TATCCTGTCA CATGTTGCCA AATATTTTGA TCAAGAAATG 
CTGAATGTCC ATAATTTGAA TTACTCCAGC TCAAGGACCT TACTTTTCCA GAGATTTTCC 
GTCATCTTTA TGGATGTACT CTTTGTGTAT GCTGTCCGTG AGTGCTGTAA ATGCATTGAT 
GGAAAAAAAG TGGGTAAAGA ACTTACAGAA AAGCCAAAAT TTATTCTGTC GGTATTACTT 
CTGTGGAACT TCGGGTTATT AATTGTGGAC CATATTCATT TTCAGTACAA TGGCTTTTTA 
TTTGGATTAA TGCTACTCTC CATTGCACGA TTATTTCAGA AAAGGCATAT GGAAGGAGCA 
TTTCTCTTTG CTGTTCTCCT ACATTTCAAG CATATCTACC TCTATGTAGC ACCAGCTTAT 
GGTGTATATC TGCTGCGATC CTACTGTTTC ACTGCAAATA AACCAGATGG GTCTATTCGA 
TGGAAGAGTT TCAGCTTTGT TCGTGTTATT TCCCTGGGAC TGGTTGTTTT CTTAGTTTCT 
GCTCTTTCAT TGGGTCCTTT CCTGGCCTTG AATCAGCTGC CTCAAGTCTT TTCCCGACTC 
TTTCCTTTCA AGAGGGGCCT CTGTCATGCA TATTGGGCTC CAAACTTCTG GGCTTTGTAC 
AATGCTTTGG ACAAAGTGCT GTCTGTCATC GGTTTGAAAT TGAAATTTCT TGATCCCAAC 
AATATTCCCA AGGCCTCAAT GACAAGTGGT TTGGTTCAGC AGTTCCAACA CACAGTCCTT 
CCCTCAGTGA CTCCCTTGGC AACCCTCATC TGCACACTGA TTGCCATATT GCCCTCTATT 
TTCTGTCTTT GGTTTAAACC CCAAGGGCCC AGAGGCTTTC TCCGATGTCT AACTCTTTGT 
GCCTTGAGCT CCTTTATGTT TGGGTGGCAT GTTCATGAAA AAGCCATACT TCTAGCAATT 
CTCCCAATGA GCCTTTTGTC TGTGGGAAAA GCAGGAGACG CTTCGATTTT TCTGATTCTG 
ACCACAACAG GACATTATTC CCTCTTTCCT CTGCTCTTCA CTGCACCAGA ACTTCCCATT 
AAAATCTTAC TCATGTTACT ATTCACCATA TATAGTATTT CGTCACTGAA GACTTTATTC 
AGACGGAGTT TCACCCTTGT TGCCCAGGCT GGAGTGCAAT GGCACGATCT CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873763.1
CDS	841..2217
Translation	MDVGPRLKAWKPRSNHEMVVCIHHSTDFEVHRNWLAITHSLPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRRSFTLVAQAGVQWHDLS

Target ORF information:

RefSeq Version	XM_017018274.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG8 alpha-1,3-glucosyltransferase (ALG8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018274.1

ORF Insert Sequence:

ATGGATGTAG GGCCAAGACT GAAAGCGTGG AAACCAAGAA GCAACCATGA AATGGTGGTG 
TGTATACACC ATTCCACAGA TTTTGAAGTA CACCGAAACT GGCTTGCTAT CACTCACAGT 
TTGCCAATAT CACAGTGGTA TTATGAGGCA ACTTCAGAGT GGACGTTGGA TTACCCCCCT 
TTCTTTGCAT GGTTTGAGTA TATCCTGTCA CATGTTGCCA AATATTTTGA TCAAGAAATG 
CTGAATGTCC ATAATTTGAA TTACTCCAGC TCAAGGACCT TACTTTTCCA GAGATTTTCC 
GTCATCTTTA TGGATGTACT CTTTGTGTAT GCTGTCCGTG AGTGCTGTAA ATGCATTGAT 
GGAAAAAAAG TGGGTAAAGA ACTTACAGAA AAGCCAAAAT TTATTCTGTC GGTATTACTT 
CTGTGGAACT TCGGGTTATT AATTGTGGAC CATATTCATT TTCAGTACAA TGGCTTTTTA 
TTTGGATTAA TGCTACTCTC CATTGCACGA TTATTTCAGA AAAGGCATAT GGAAGGAGCA 
TTTCTCTTTG CTGTTCTCCT ACATTTCAAG CATATCTACC TCTATGTAGC ACCAGCTTAT 
GGTGTATATC TGCTGCGATC CTACTGTTTC ACTGCAAATA AACCAGATGG GTCTATTCGA 
TGGAAGAGTT TCAGCTTTGT TCGTGTTATT TCCCTGGGAC TGGTTGTTTT CTTAGTTTCT 
GCTCTTTCAT TGGGTCCTTT CCTGGCCTTG AATCAGCTGC CTCAAGTCTT TTCCCGACTC 
TTTCCTTTCA AGAGGGGCCT CTGTCATGCA TATTGGGCTC CAAACTTCTG GGCTTTGTAC 
AATGCTTTGG ACAAAGTGCT GTCTGTCATC GGTTTGAAAT TGAAATTTCT TGATCCCAAC 
AATATTCCCA AGGCCTCAAT GACAAGTGGT TTGGTTCAGC AGTTCCAACA CACAGTCCTT 
CCCTCAGTGA CTCCCTTGGC AACCCTCATC TGCACACTGA TTGCCATATT GCCCTCTATT 
TTCTGTCTTT GGTTTAAACC CCAAGGGCCC AGAGGCTTTC TCCGATGTCT AACTCTTTGT 
GCCTTGAGCT CCTTTATGTT TGGGTGGCAT GTTCATGAAA AAGCCATACT TCTAGCAATT 
CTCCCAATGA GCCTTTTGTC TGTGGGAAAA GCAGGAGACG CTTCGATTTT TCTGATTCTG 
ACCACAACAG GACATTATTC CCTCTTTCCT CTGCTCTTCA CTGCACCAGA ACTTCCCATT 
AAAATCTTAC TCATGTTACT ATTCACCATA TATAGTATTT CGTCACTGAA GACTTTATTC 
AGACGGAGTT TCACCCTTGT TGCCCAGGCT GGAGTGCAAT GGCACGATCT CAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Isolated polycystic liver disease genes define effectors of polycystin-1 function.
The Journal of clinical investigation127(5)1772-1785(2017 May)
Besse W,Dong K,Choi J,Punia S,Fedeles SV,Choi M,Gallagher AR,Huang EB,Gulati A,Knight J,Mane S,Tahvanainen E,Tahvanainen P,Sanna-Cherchi S,Lifton RP,Watnick T,Pei YP,Torres VE,Somlo S

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

ALG8-CDG: novel patients and review of the literature.
Orphanet journal of rare diseases1073(2015 Jun)
H?ck M,Wegleiter K,Ralser E,Kiechl-Kohlendorfer U,Scholl-B?rgi S,Fauth C,Steichen E,Pichler K,Lefeber DJ,Matthjis G,Keldermans L,Maurer K,Zschocke J,Karall D

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

Wrinkled skin and fat pads in patients with ALG8-CDG: revisiting skin manifestations in congenital disorders of glycosylation.
Pediatric dermatology31(1)e1-5(2014 Jan-Feb)
Kouwenberg D,Gardeitchik T,Mohamed M,Lefeber DJ,Morava E

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ALG8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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