REEP5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	REEP5
Entrez Gene ID	7905
Full Name	receptor accessory protein 5
Synonyms	C5orf18,D5S346,DP1,TB2,YOP1,Yip2e
General protein information	Preferred Names receptor accessory protein 5 Names receptor expression-enhancing protein 5 deleted in polyposis 1 polyposis coli region hypothetical protein DP1 polyposis locus protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q22.2
Disorder MIM:	125265

mRNA and Protein(s)

mRNA	Protein	Name
NM_005669.4	NP_005660.4	receptor expression-enhancing protein 5
XM_017009844.1	XP_016865333.1	receptor expression-enhancing protein 5 isoform X1
NM_005669.5	NP_005660.4	receptor expression-enhancing protein 5
XM_017009844.2	XP_016865333.1	receptor expression-enhancing protein 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	REEP5	XP_003310831.2
	LOC694140	XP_001082843.2
Danio rerio (zebrafish)	reep5	NP_956352.1
Schizosaccharomyces pombe (fission yeast)	yop1	NP_588478.1
Xenopus tropicalis (tropical clawed frog)	reep5	NP_001011272.1
Homo sapiens (human)	REEP5	NP_005660.4
Rattus norvegicus (Norway rat)	Reep5	NP_001102358.2
Drosophila melanogaster (fruit fly)	CG8331	NP_001188928.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004819	XP_317989.3
Eremothecium gossypii	AGOS_ADR063W	NP_984159.2
Canis lupus familiaris (dog)	LOC479137	XP_536283.5
Mus musculus (house mouse)	Reep5	NP_031900.3
Gallus gallus (chicken)	REEP5	NP_001239006.1
Drosophila melanogaster (fruit fly)	CG4960	NP_651429.1
Kluyveromyces lactis	KLLA0E06601g	XP_454246.1
Magnaporthe oryzae (rice blast fungus)	MGG_12127	XP_003719851.1
Bos taurus (cattle)	REEP5	NP_001040070.1
Danio rerio (zebrafish)	LOC100534894	XP_003199347.1
Caenorhabditis elegans (roundworm)	yop-1	NP_491033.1
Saccharomyces cerevisiae (baker's yeast)	YOP1	NP_015353.1
Neurospora crassa	NCU06702	XP_961017.1

Gene Ontology
Bibliography

Related articles in PubMed

The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression.
Park CR, You DJ, Park S, Mander S, Jang DE, Yeom SC, Oh SH, Ahn C, Lee SH, Seong JY, Hwang JI
Scientific reports639041(2016 Dec)

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Chang J, Lee S, Blackstone C
Proceedings of the National Academy of Sciences of the United States of America110(37)14954-9(2013 Sep)

Association of APC and REEP5 gene polymorphisms with major depression disorder and treatment response to antidepressants in a Han Chinese population.
Yang Z, Ma X, Wang Y, Wang J, Xiang B, Wu J, Deng W, Li M, Wang Q, Li T
General hospital psychiatry34(5)571-7(2012 Sep-Oct)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

To determine the pathogenesis and treatment response of major depressive disorder. REEP5 gene polymorphisms may influence antidepressant treatment response in MDD.
Title: Association of APC and REEP5 gene polymorphisms with major depression disorder and treatment response to antidepressants in a Han Chinese population.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following REEP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the REEP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05008	NM_005669.5 Latest version!	Homo sapiens receptor accessory protein 5 (REEP5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu96065	XM_017009844.2 Latest version!	Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu05008	NM_005669.4	Homo sapiens receptor accessory protein 5 (REEP5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu96065	XM_017009844.1	Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

REEP5 ( NM_005669.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005660.4 Homo sapiens receptor accessory protein 5 (REEP5), mRNA.

Price & Availability↑

CloneID	OHu05008
Clone ID Related Accession (Same CDS sequence)	NM_005669.4 , NM_005669.5
Accession Version	NM_005669.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA807043.1, BC000232.1 and AC008575.7. On Sep 30, 2006 this sequence version replaced NM_005669.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.183555.1, SRR1803612.41716.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG CGAAGAAAGC TACCGTGAAT 
TTACTGGGTG AAGAAAAGAA GAGCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005660.4
CDS	145..714
Translation	MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST

Target ORF information:

RefSeq Version	NM_005669.4
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 5 (REEP5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005669.4

ORF Insert Sequence:

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG CGAAGAAAGC TACCGTGAAT 
TTACTGGGTG AAGAAAAGAA GAGCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP5 ( NM_005669.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005660.4 Homo sapiens receptor accessory protein 5 (REEP5), mRNA.

Price & Availability↑

CloneID	OHu05008
Clone ID Related Accession (Same CDS sequence)	NM_005669.4 , NM_005669.5
Accession Version	NM_005669.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA807043.1, BC000232.1 and AC008575.7. On Nov 22, 2018 this sequence version replaced NM_005669.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.41716.1, SRR1803612.60533.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379638.9/ ENSP00000368959.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG CGAAGAAAGC TACCGTGAAT 
TTACTGGGTG AAGAAAAGAA GAGCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005660.4
CDS	38..607
Translation	MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST

Target ORF information:

RefSeq Version	NM_005669.5
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 5 (REEP5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005669.5

ORF Insert Sequence:

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG CGAAGAAAGC TACCGTGAAT 
TTACTGGGTG AAGAAAAGAA GAGCACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP5 ( XM_017009844.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865333.1 Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96065
Clone ID Related Accession (Same CDS sequence)	XM_017009844.1 , XM_017009844.2
Accession Version	XM_017009844.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG GTAAGACTCA GGAACAAGAT 
GGCCCCACAT GTGAGAGGAG ATGTGACACA CTGGGCTCAA ATAACAGGCT TCCTGGCCTT 
CTTGTCTTAT CACCACCCCT CAGCCAAATG CCAACATTAC TCTGGGATTT CTTTACAAAG 
TCTTTGCCTA TTGAGAACAC TTACAGTTCT CGACTTTTCC CAAGACTCTT CCTCCATGCC 
ACATTTAATG TAGCCTTCAG TCAGAACATT AGGAAAAATG ACTTTCCTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865333.1
CDS	62..835
Translation	MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEGKTQEQDGPTCERRCDTLGSNNRLPGLLVLSPPLSQMPTLLWDFFTKSLPIENTYSSRLFPRLFLHATFNVAFSQNIRKNDFPW

Target ORF information:

RefSeq Version	XM_017009844.1
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009844.1

ORF Insert Sequence:

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG GTAAGACTCA GGAACAAGAT 
GGCCCCACAT GTGAGAGGAG ATGTGACACA CTGGGCTCAA ATAACAGGCT TCCTGGCCTT 
CTTGTCTTAT CACCACCCCT CAGCCAAATG CCAACATTAC TCTGGGATTT CTTTACAAAG 
TCTTTGCCTA TTGAGAACAC TTACAGTTCT CGACTTTTCC CAAGACTCTT CCTCCATGCC 
ACATTTAATG TAGCCTTCAG TCAGAACATT AGGAAAAATG ACTTTCCTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REEP5 ( XM_017009844.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865333.1 Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu96065
Clone ID Related Accession (Same CDS sequence)	XM_017009844.1 , XM_017009844.2
Accession Version	XM_017009844.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	receptor expression-enhancing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017009844.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG GTAAGACTCA GGAACAAGAT 
GGCCCCACAT GTGAGAGGAG ATGTGACACA CTGGGCTCAA ATAACAGGCT TCCTGGCCTT 
CTTGTCTTAT CACCACCCCT CAGCCAAATG CCAACATTAC TCTGGGATTT CTTTACAAAG 
TCTTTGCCTA TTGAGAACAC TTACAGTTCT CGACTTTTCC CAAGACTCTT CCTCCATGCC 
ACATTTAATG TAGCCTTCAG TCAGAACATT AGGAAAAATG ACTTTCCTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865333.1
CDS	100..873
Translation	MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEGKTQEQDGPTCERRCDTLGSNNRLPGLLVLSPPLSQMPTLLWDFFTKSLPIENTYSSRLFPRLFLHATFNVAFSQNIRKNDFPW

Target ORF information:

RefSeq Version	XM_017009844.2
Organism	Homo sapiens(human)
Definition	Homo sapiens receptor accessory protein 5 (REEP5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009844.2

ORF Insert Sequence:

ATGTCTGCGG CCATGAGGGA GAGGTTCGAC CGGTTCCTGC ACGAGAAGAA CTGCATGACT 
GACCTTCTGG CCAAGCTCGA GGCCAAAACC GGCGTGAACA GGAGCTTCAT CGCTCTTGGT 
GTCATCGGAC TGGTGGCCTT GTACCTGGTG TTCGGTTATG GAGCCTCTCT CCTCTGCAAC 
CTGATAGGAT TTGGCTACCC AGCCTACATC TCAATTAAAG CTATAGAGAG TCCCAACAAA 
GAAGATGATA CCCAGTGGCT GACCTACTGG GTAGTGTATG GTGTGTTCAG CATTGCTGAA 
TTCTTCTCTG ATATCTTCCT GTCATGGTTC CCCTTCTACT ACATGCTGAA GTGTGGCTTC 
CTGTTGTGGT GCATGGCCCC GAGCCCTTCT AATGGGGCTG AACTGCTCTA CAAGCGCATC 
ATCCGTCCTT TCTTCCTGAA GCACGAGTCC CAGATGGACA GTGTGGTCAA GGACCTTAAA 
GACAAGGCCA AAGAGACTGC AGATGCCATC ACTAAAGAAG GTAAGACTCA GGAACAAGAT 
GGCCCCACAT GTGAGAGGAG ATGTGACACA CTGGGCTCAA ATAACAGGCT TCCTGGCCTT 
CTTGTCTTAT CACCACCCCT CAGCCAAATG CCAACATTAC TCTGGGATTT CTTTACAAAG 
TCTTTGCCTA TTGAGAACAC TTACAGTTCT CGACTTTTCC CAAGACTCTT CCTCCATGCC 
ACATTTAATG TAGCCTTCAG TCAGAACATT AGGAAAAATG ACTTTCCTTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression.
Scientific reports639041(2016 Dec)
Park CR,You DJ,Park S,Mander S,Jang DE,Yeom SC,Oh SH,Ahn C,Lee SH,Seong JY,Hwang JI

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Proceedings of the National Academy of Sciences of the United States of America110(37)14954-9(2013 Sep)
Chang J,Lee S,Blackstone C

Association of APC and REEP5 gene polymorphisms with major depression disorder and treatment response to antidepressants in a Han Chinese population.
General hospital psychiatry34(5)571-7(2012 Sep-Oct)
Yang Z,Ma X,Wang Y,Wang J,Xiang B,Wu J,Deng W,Li M,Wang Q,Li T

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

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REEP5 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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