CACNG1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CACNG1
Entrez Gene ID	786
Full Name	calcium voltage-gated channel auxiliary subunit gamma 1
Synonyms	CACNLG
General protein information	Preferred Names calcium voltage-gated channel auxiliary subunit gamma 1 Names voltage-dependent calcium channel gamma-1 subunit L-type calcium channel gamma polypeptide calcium channel, voltage-dependent, gamma subunit 1 dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma neuronal dihydropyridine-sensitive calcium channel gamma subunit
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q24.2
Summary	Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010].
Disorder MIM:	114209

mRNA and Protein(s)

mRNA	Protein	Name
NM_000727.3	NP_000718.1	voltage-dependent calcium channel gamma-1 subunit
NM_000727.4	NP_000718.1	voltage-dependent calcium channel gamma-1 subunit

Pathways from BioSystems

Homologies

Homo sapiens (human)	CACNG1	NP_000718.1
Gallus gallus (chicken)	CACNG1	NP_001264935.1
Danio rerio (zebrafish)	cacng1	NP_999849.1
Pan troglodytes (chimpanzee)	CACNG1	XP_001163880.1
Xenopus tropicalis (tropical clawed frog)	cacng1	NP_001011035.1
Gallus gallus (chicken)	LOC100859535	XP_003642389.1
Danio rerio (zebrafish)	LOC571193	XP_699850.2
Canis lupus familiaris (dog)	CACNG1	XP_853551.1
Bos taurus (cattle)	CACNG1	NP_001073806.1
Mus musculus (house mouse)	Cacng1	NP_031608.1
Rattus norvegicus (Norway rat)	Cacng1	NP_062128.1

Gene Ontology
Bibliography

Related articles in PubMed

Calcium channel gamma subunits: a functionally diverse protein family.
Chen RS, Deng TC, Garcia T, Sellers ZM, Best PM
Cell biochemistry and biophysics47(2)178-86(2007)

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Chu PJ, Robertson HM, Best PM
Gene280(1-2)37-48(2001 Dec)

A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.
Burgess DL, Gefrides LA, Foreman PJ, Noebels JL
Genomics71(3)339-50(2001 Feb)

Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.
Burgess DL, Davis CF, Gefrides LA, Noebels JL
Genome research9(12)1204-13(1999 Dec)

A somatic cell hybrid panel for distal 17q: GDIA1 maps to 17q25.3.
Wagner T, Tommerup N, Wirth J, Leffers H, Zimmer J, Back E, Weissenbach J, Scherer G
Cytogenetics and cell genetics76(3-4)172-5(1997)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CACNG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CACNG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12251	NM_000727.4 Latest version!	Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu12251	NM_000727.3	Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CACNG1 ( NM_000727.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000718.1 Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.

Price & Availability↑

CloneID	OHu12251
Clone ID Related Accession (Same CDS sequence)	NM_000727.3 , NM_000727.4
Accession Version	NM_000727.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	voltage-dependent calcium channel gamma-1 subunit
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA898357.1, BC113486.1, AF086300.1 and AC005544.1. On Dec 3, 2010 this sequence version replaced NM_000727.2. ##Evidence-Data-START## Transcript exon combination :: L07738.1, ERR279827.4076.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427, SAMEA2158800 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCCAGA CCAAAATGCT GAAGGTCCGC GTGACCCTCT TCTGCATCCT GGCAGGCATC 
GTGCTGGCCA TGACAGCCGT GGTAACCGAC CACTGGGCTG TGCTGAGCCC CCACATGGAG 
CACCACAACA CTACCTGCGA GGCGGCCCAC TTCGGCCTCT GGCGGATTTG TACCAAGCGC 
ATCCCCATGG ACGACAGCAA GACCTGCGGG CCCATCACCC TGCCCGGGGA GAAGAACTGT 
TCCTACTTCA GGCATTTTAA CCCCGGCGAG AGCTCGGAGA TCTTCGAATT CACCACTCAG 
AAGGAGTACA GCATCTCGGC AGCCGCCATC GCCATCTTCA GCCTTGGCTT CATCATCCTG 
GGCAGCCTCT GTGTCCTCCT GTCCCTCGGG AAGAAGAGGG ACTATCTGCT GCGACCCGCG 
TCCATGTTCT ATGCCTTTGC AGGTCTCTGC ATCCTCGTCT CGGTGGAGGT CATGCGGCAG 
TCGGTGAAGC GCATGATTGA CAGTGAGGAC ACCGTCTGGA TCGAGTACTA TTACTCCTGG 
TCCTTTGCCT GCGCCTGTGC CGCCTTCATC CTCCTCTTTC TCGGCGGTCT CGCCCTCCTG 
CTGTTCTCCC TGCCTCGAAT GCCCCGGAAC CCATGGGAGT CCTGCATGGA TGCTGAGCCC 
GAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000718.1
CDS	126..794
Translation	MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH

Target ORF information:

RefSeq Version	NM_000727.3
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000727.3

ORF Insert Sequence:

ATGTCCCAGA CCAAAATGCT GAAGGTCCGC GTGACCCTCT TCTGCATCCT GGCAGGCATC 
GTGCTGGCCA TGACAGCCGT GGTAACCGAC CACTGGGCTG TGCTGAGCCC CCACATGGAG 
CACCACAACA CTACCTGCGA GGCGGCCCAC TTCGGCCTCT GGCGGATTTG TACCAAGCGC 
ATCCCCATGG ACGACAGCAA GACCTGCGGG CCCATCACCC TGCCCGGGGA GAAGAACTGT 
TCCTACTTCA GGCATTTTAA CCCCGGCGAG AGCTCGGAGA TCTTCGAATT CACCACTCAG 
AAGGAGTACA GCATCTCGGC AGCCGCCATC GCCATCTTCA GCCTTGGCTT CATCATCCTG 
GGCAGCCTCT GTGTCCTCCT GTCCCTCGGG AAGAAGAGGG ACTATCTGCT GCGACCCGCG 
TCCATGTTCT ATGCCTTTGC AGGTCTCTGC ATCCTCGTCT CGGTGGAGGT CATGCGGCAG 
TCGGTGAAGC GCATGATTGA CAGTGAGGAC ACCGTCTGGA TCGAGTACTA TTACTCCTGG 
TCCTTTGCCT GCGCCTGTGC CGCCTTCATC CTCCTCTTTC TCGGCGGTCT CGCCCTCCTG 
CTGTTCTCCC TGCCTCGAAT GCCCCGGAAC CCATGGGAGT CCTGCATGGA TGCTGAGCCC 
GAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CACNG1 ( NM_000727.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000718.1 Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.

Price & Availability↑

CloneID	OHu12251
Clone ID Related Accession (Same CDS sequence)	NM_000727.3 , NM_000727.4
Accession Version	NM_000727.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	voltage-dependent calcium channel gamma-1 subunit
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA898357.1, BC113486.1, AF086300.1 and AC005544.1. On Nov 22, 2018 this sequence version replaced NM_000727.3. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.187776.1, L07738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153427, SAMEA2158800 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000226021.5/ ENSP00000226021.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCCAGA CCAAAATGCT GAAGGTCCGC GTGACCCTCT TCTGCATCCT GGCAGGCATC 
GTGCTGGCCA TGACAGCCGT GGTAACCGAC CACTGGGCTG TGCTGAGCCC CCACATGGAG 
CACCACAACA CTACCTGCGA GGCGGCCCAC TTCGGCCTCT GGCGGATTTG TACCAAGCGC 
ATCCCCATGG ACGACAGCAA GACCTGCGGG CCCATCACCC TGCCCGGGGA GAAGAACTGT 
TCCTACTTCA GGCATTTTAA CCCCGGCGAG AGCTCGGAGA TCTTCGAATT CACCACTCAG 
AAGGAGTACA GCATCTCGGC AGCCGCCATC GCCATCTTCA GCCTTGGCTT CATCATCCTG 
GGCAGCCTCT GTGTCCTCCT GTCCCTCGGG AAGAAGAGGG ACTATCTGCT GCGACCCGCG 
TCCATGTTCT ATGCCTTTGC AGGTCTCTGC ATCCTCGTCT CGGTGGAGGT CATGCGGCAG 
TCGGTGAAGC GCATGATTGA CAGTGAGGAC ACCGTCTGGA TCGAGTACTA TTACTCCTGG 
TCCTTTGCCT GCGCCTGTGC CGCCTTCATC CTCCTCTTTC TCGGCGGTCT CGCCCTCCTG 
CTGTTCTCCC TGCCTCGAAT GCCCCGGAAC CCATGGGAGT CCTGCATGGA TGCTGAGCCC 
GAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000718.1
CDS	108..776
Translation	MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH

Target ORF information:

RefSeq Version	NM_000727.4
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000727.4

ORF Insert Sequence:

ATGTCCCAGA CCAAAATGCT GAAGGTCCGC GTGACCCTCT TCTGCATCCT GGCAGGCATC 
GTGCTGGCCA TGACAGCCGT GGTAACCGAC CACTGGGCTG TGCTGAGCCC CCACATGGAG 
CACCACAACA CTACCTGCGA GGCGGCCCAC TTCGGCCTCT GGCGGATTTG TACCAAGCGC 
ATCCCCATGG ACGACAGCAA GACCTGCGGG CCCATCACCC TGCCCGGGGA GAAGAACTGT 
TCCTACTTCA GGCATTTTAA CCCCGGCGAG AGCTCGGAGA TCTTCGAATT CACCACTCAG 
AAGGAGTACA GCATCTCGGC AGCCGCCATC GCCATCTTCA GCCTTGGCTT CATCATCCTG 
GGCAGCCTCT GTGTCCTCCT GTCCCTCGGG AAGAAGAGGG ACTATCTGCT GCGACCCGCG 
TCCATGTTCT ATGCCTTTGC AGGTCTCTGC ATCCTCGTCT CGGTGGAGGT CATGCGGCAG 
TCGGTGAAGC GCATGATTGA CAGTGAGGAC ACCGTCTGGA TCGAGTACTA TTACTCCTGG 
TCCTTTGCCT GCGCCTGTGC CGCCTTCATC CTCCTCTTTC TCGGCGGTCT CGCCCTCCTG 
CTGTTCTCCC TGCCTCGAAT GCCCCGGAAC CCATGGGAGT CCTGCATGGA TGCTGAGCCC 
GAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Calcium channel gamma subunits: a functionally diverse protein family.
Cell biochemistry and biophysics47(2)178-86(2007)
Chen RS,Deng TC,Garcia T,Sellers ZM,Best PM

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Gene280(1-2)37-48(2001 Dec)
Chu PJ,Robertson HM,Best PM

A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.
Genomics71(3)339-50(2001 Feb)
Burgess DL,Gefrides LA,Foreman PJ,Noebels JL

Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.
Genome research9(12)1204-13(1999 Dec)
Burgess DL,Davis CF,Gefrides LA,Noebels JL

A somatic cell hybrid panel for distal 17q: GDIA1 maps to 17q25.3.
Cytogenetics and cell genetics76(3-4)172-5(1997)
Wagner T,Tommerup N,Wirth J,Leffers H,Zimmer J,Back E,Weissenbach J,Scherer G

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CACNG1 cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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