CA11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CA11
Entrez Gene ID	770
Full Name	carbonic anhydrase 11
Synonyms	CARPX1
General protein information	Preferred Names carbonic anhydrase 11 Names carbonic anhydrase-related protein 11 CA-RP II CA-XI CARP XI CARP-2 carbonic anhydrase XI carbonic anhydrase-related protein 2 carbonic anhydrase-related protein XI
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008].
Disorder MIM:	604644

mRNA and Protein(s)

mRNA	Protein	Name
NM_001217.4	NP_001208.2	carbonic anhydrase-related protein 11 precursor
NM_001217.3	NP_001208.2	carbonic anhydrase-related protein 11 precursor
NM_001217.5	NP_001208.2	carbonic anhydrase-related protein 11 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CA11	XP_001171568.1
	CA11	XP_001113730.2
Canis lupus familiaris (dog)	CA11	XP_852031.1
Bos taurus (cattle)	CA11	NP_783648.1
Xenopus tropicalis (tropical clawed frog)	LOC100493884	XP_002938168.2
Homo sapiens (human)	CA11	NP_001208.2
Mus musculus (house mouse)	Car11	NP_033930.1
Rattus norvegicus (Norway rat)	Car11	NP_783639.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
Liang Y, Tang W, Huang T, Gao Y, Tan A, Yang X, Zhang H, Hu Y, Qin X, Li S, Zhang S, Mo L, Liang Z, Shi D, Huang Z, Guan Y, Zhou J, Winkler C, O'Brien SJ, Xu J, Mo Z, Peng T
PloS one9(6)e97923(2014)

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and ? fetoprotein and their associations with cancer risk.
He M, Wu C, Xu J, Guo H, Yang H, Zhang X, Sun J, Yu D, Zhou L, Peng T, He Y, Gao Y, Yuan J, Deng Q, Dai X, Tan A, Feng Y, Zhang H, Min X, Yang X, Zhu J, Zhai K, Chang J, Qin X, Tan W, Hu Y, Lang M, Tao S, Li Y, Li Y, Feng J, Li D, Kim ST, Zhang S, Zhang H, Zheng SL, Gui L, Wang Y, Wei S, Wang F, Fang W, Liang Y, Zhai Y, Chen W, Miao X, Zhou G, Hu FB, Lin D, Mo Z, Wu T
Gut63(1)143-51(2014 Jan)

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

Nature genetics43(10)977-83(2011 Sep)

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.
Ikram MK, Sim X, Xueling S, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, Rivadeneira F, Hofman A, de Jong PT, van Duijn CM, Kao L, Cheng CY, Smith AV, Glazer NL, Lumley T, McKnight B, Psaty BM, Jonasson F, Eiriksdottir G, Aspelund T, , Harris TB, Launer LJ, Taylor KD, Li X, Iyengar SK, Xi Q, Sivakumaran TA, Mackey DA, Macgregor S, Martin NG, Young TL, Bis JC, Wiggins KL, Heckbert SR, Hammond CJ, Andrew T, Fahy S, Attia J, Holliday EG, Scott RJ, Islam FM, Rotter JI, McAuley AK, Boerwinkle E, Tai ES, Gudnason V, Siscovick DS, Vingerling JR, Wong TY
PLoS genetics6(10)e1001184(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CA11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CA11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02823	NM_001217.5 Latest version!	Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu02823	NM_001217.3	Homo sapiens carbonic anhydrase XI (CA11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02823	NM_001217.4	Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CA11 ( NM_001217.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001208.2 Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02823
Clone ID Related Accession (Same CDS sequence)	NM_001217.4 , NM_001217.3 , NM_001217.5
Accession Version	NM_001217.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	carbonic anhydrase-related protein 11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX440526.2, AC008888.7, AY358967.1, AF067662.1, HY313058.1 and AI568635.1. On Apr 8, 2016 this sequence version replaced NM_001217.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.711729.1, SRR1803613.155447.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001208.2
CDS	681..1667
Translation	MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR

Target ORF information:

RefSeq Version	NM_001217.4
Organism	Homo sapiens(human)
Definition	Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001217.4

ORF Insert Sequence:

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CA11 ( NM_001217.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001208.2 Homo sapiens carbonic anhydrase XI (CA11), mRNA.

Price & Availability↑

CloneID	OHu02823
Clone ID Related Accession (Same CDS sequence)	NM_001217.4 , NM_001217.3 , NM_001217.5
Accession Version	NM_001217.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	carbonic anhydrase-related protein 11 precursor
Comment

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001208.2
Translation	MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR

Target ORF information:

RefSeq Version	NM_001217.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens carbonic anhydrase XI (CA11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001217.3

ORF Insert Sequence:

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CA11 ( NM_001217.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001208.2 Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02823
Clone ID Related Accession (Same CDS sequence)	NM_001217.4 , NM_001217.3 , NM_001217.5
Accession Version	NM_001217.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	carbonic anhydrase-related protein 11 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008888.7, AY358967.2, DR978420.1 and AI568635.1. On Nov 23, 2018 this sequence version replaced NM_001217.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.681089.1, SRR3476690.1112426.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000084798.9/ ENSP00000084798.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001208.2
CDS	556..1542
Translation	MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR

Target ORF information:

RefSeq Version	NM_001217.5
Organism	Homo sapiens(human)
Definition	Homo sapiens carbonic anhydrase 11 (CA11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001217.5

ORF Insert Sequence:

ATGGGGGCTG CAGCTCGTCT GAGCGCCCCT CGAGCGCTGG TACTCTGGGC TGCACTGGGG 
GCAGCAGCTC ACATCGGACC AGCACCTGAC CCCGAGGACT GGTGGAGCTA CAAGGATAAT 
CTCCAGGGAA ACTTCGTGCC AGGGCCTCCT TTCTGGGGCC TGGTGAATGC AGCGTGGAGT 
CTGTGTGCTG TGGGGAAGCG GCAGAGCCCC GTGGATGTGG AGCTGAAGAG GGTTCTTTAT 
GACCCCTTTC TGCCCCCATT AAGGCTCAGC ACTGGAGGAG AGAAGCTCCG GGGAACCTTG 
TACAACACCG GCCGACATGT CTCCTTCCTG CCTGCACCCC GACCTGTGGT CAATGTGTCT 
GGAGGTCCCC TCCTTTACAG CCACCGACTC AGTGAACTGC GGCTGCTGTT TGGAGCTCGC 
GACGGAGCCG GCTCGGAACA TCAGATCAAC CACCAGGGCT TCTCTGCTGA GGTGCAGCTC 
ATTCACTTCA ACCAGGAACT CTACGGGAAT TTCAGCGCTG CCTCCCGCGG CCCCAATGGC 
CTGGCCATTC TCAGCCTCTT TGTCAACGTT GCCAGTACCT CTAACCCATT CCTCAGTCGC 
CTCCTTAACC GCGACACCAT CACTCGCATC TCCTACAAGA ATGATGCCTA CTTTCTTCAA 
GACCTGAGCC TGGAGCTCCT GTTCCCTGAA TCCTTCGGCT TCATCACCTA TCAGGGCTCT 
CTCAGCACCC CGCCCTGCTC CGAGACTGTC ACCTGGATCC TCATTGACCG GGCCCTCAAT 
ATCACCTCCC TTCAGATGCA CTCCCTGAGA CTCCTGAGCC AGAATCCTCC ATCTCAGATC 
TTCCAGAGCC TCAGCGGTAA CAGCCGGCCC CTGCAGCCCT TGGCCCACAG GGCACTGAGG 
GGCAACAGGG ACCCCCGGCA CCCCGAGAGG CGCTGCCGAG GCCCCAACTA CCGCCTGCAT 
GTGGATGGTG TCCCCCATGG TCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
PloS one9(6)e97923(2014)
Liang Y,Tang W,Huang T,Gao Y,Tan A,Yang X,Zhang H,Hu Y,Qin X,Li S,Zhang S,Mo L,Liang Z,Shi D,Huang Z,Guan Y,Zhou J,Winkler C,O'Brien SJ,Xu J,Mo Z,Peng T

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and ? fetoprotein and their associations with cancer risk.
Gut63(1)143-51(2014 Jan)
He M,Wu C,Xu J,Guo H,Yang H,Zhang X,Sun J,Yu D,Zhou L,Peng T,He Y,Gao Y,Yuan J,Deng Q,Dai X,Tan A,Feng Y,Zhang H,Min X,Yang X,Zhu J,Zhai K,Chang J,Qin X,Tan W,Hu Y,Lang M,Tao S,Li Y,Li Y,Feng J,Li D,Kim ST,Zhang S,Zhang H,Zheng SL,Gui L,Wang Y,Wei S,Wang F,Fang W,Liang Y,Zhai Y,Chen W,Miao X,Zhou G,Hu FB,Lin D,Mo Z,Wu T

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
Nature genetics43(10)977-83(2011 Sep)

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.
PLoS genetics6(10)e1001184(2010 Oct)
Ikram MK,Sim X,Xueling S,Jensen RA,Cotch MF,Hewitt AW,Ikram MA,Wang JJ,Klein R,Klein BE,Breteler MM,Cheung N,Liew G,Mitchell P,Uitterlinden AG,Rivadeneira F,Hofman A,de Jong PT,van Duijn CM,Kao L,Cheng CY,Smith AV,Glazer NL,Lumley T,McKnight B,Psaty BM,Jonasson F,Eiriksdottir G,Aspelund T,,Harris TB,Launer LJ,Taylor KD,Li X,Iyengar SK,Xi Q,Sivakumaran TA,Mackey DA,Macgregor S,Martin NG,Young TL,Bis JC,Wiggins KL,Heckbert SR,Hammond CJ,Andrew T,Fahy S,Attia J,Holliday EG,Scott RJ,Islam FM,Rotter JI,McAuley AK,Boerwinkle E,Tai ES,Gudnason V,Siscovick DS,Vingerling JR,Wong TY

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CA11 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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