ZNF10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZNF10
Entrez Gene ID	7556
Full Name	zinc finger protein 10
Synonyms	KOX1
General protein information	Preferred Names zinc finger protein 10 Names zinc finger protein 10 zinc finger protein 10 (KOX 1) zinc finger protein KOX1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.33
Summary	The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein. [provided by RefSeq, Jul 2008].
Disorder MIM:	194538

mRNA and Protein(s)

mRNA	Protein	Name
NM_015394.4	NP_056209.2	zinc finger protein 10
NM_015394.5	NP_056209.2	zinc finger protein 10

Pathways from BioSystems

Homologies

	ZNF10	XP_001086718.2
Bos taurus (cattle)	ZNF10	XP_002694475.3
Homo sapiens (human)	ZNF10	NP_056209.2
Canis lupus familiaris (dog)	ZNF10	XP_005636100.1
Pan troglodytes (chimpanzee)	ZNF10	NP_001233376.1

Gene Ontology
Bibliography

Related articles in PubMed

ZNF10 inhibits HIV-1 LTR activity through interaction with NF-?B and Sp1 binding motifs.
Nishitsuji H, Sawada L, Sugiyama R, Takaku H
FEBS letters589(15)2019-25(2015 Jul)

The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1.
Born N, Thiesen HJ, Lorenz P
PloS one9(2)e87609(2014)

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.
Wang W, Cai J, Wu Y, Hu L, Chen Z, Hu J, Chen Z, Li W, Guo M, Huang Z
Cellular and molecular life sciences : CMLS70(20)3947-58(2013 Oct)

Transcriptional repression mediated by the KRAB domain of the human C2H2 zinc finger protein Kox1/ZNF10 does not require histone deacetylation.
Lorenz P, Koczan D, Thiesen HJ
Biological chemistry382(4)637-44(2001 Apr)

Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain.
Peng H, Begg GE, Harper SL, Friedman JR, Speicher DW, Rauscher FJ 3rd
The Journal of biological chemistry275(24)18000-10(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results indicate that ZNF10 could be involved in a potent intrinsic antiretroviral defense
Title: ZNF10 inhibits HIV-1 LTR activity through interaction with NF-?B and Sp1 binding motifs.

Data indicate that Xenopus laevis XFIN-AB displayed reduced potency in repression compared to human ZNF10 KRAB-AB.
Title: The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1.

The following ZNF10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZNF10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29577	NM_015394.5 Latest version!	Homo sapiens zinc finger protein 10 (ZNF10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu29577	NM_015394.4	Homo sapiens zinc finger protein 10 (ZNF10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZNF10 ( NM_015394.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056209.2 Homo sapiens zinc finger protein 10 (ZNF10), mRNA.

Price & Availability↑

CloneID	OHu29577
Clone ID Related Accession (Same CDS sequence)	NM_015394.4 , NM_015394.5
Accession Version	NM_015394.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1722bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	zinc finger protein 10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC024182.2, AL110188.1, BE895826.1 and AI972895.1. On Oct 30, 2003 this sequence version replaced NM_015394.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.243565.1, BC024182.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGCTA AGTCACTAAC TGCCTGGTCC CGGACACTGG TGACCTTCAA GGATGTATTT 
GTGGACTTCA CCAGGGAGGA GTGGAAGCTG CTGGACACTG CTCAGCAGAT CGTGTACAGA 
AATGTGATGC TGGAGAACTA TAAGAACCTG GTTTCCTTGG GTTATCAGCT TACTAAGCCA 
GATGTGATCC TCCGGTTGGA GAAGGGAGAA GAGCCCTGGC TGGTGGAGAG AGAAATTCAC 
CAAGAGACCC ATCCTGATTC AGAGACTGCA TTTGAAATCA AATCATCAGT TTCCAGCAGG 
AGCATTTTTA AAGATAAGCA ATCCTGTGAC ATTAAAATGG AAGGAATGGC AAGGAATGAT 
CTCTGGTATT TGTCATTAGA AGAAGTCTGG AAATGTAGAG ACCAGTTAGA CAAGTATCAG 
GAAAACCCAG AGAGACATTT GAGGCAAGTG GCATTCACCC AAAAGAAAGT ACTTACTCAG 
GAGAGAGTCT CTGAAAGTGG TAAATATGGG GGAAACTGTC TTCTTCCTGC TCAGCTAGTA 
CTGAGAGAGT ATTTCCATAA ACGTGACTCA CATACTAAAA GTTTAAAACA TGATTTAGTT 
CTTAATGGTC ATCAGGACAG TTGTGCAAGT AACAGTAATG AATGTGGTCA AACTTTCTGT 
CAAAACATTC ACCTTATTCA GTTTGCAAGA ACTCACACAG GTGATAAATC CTACAAATGC 
CCTGATAATG ACAACTCTCT TACTCATGGT TCATCTCTTG GTATATCAAA GGGCATACAT 
AGAGAGAAAC CCTATGAATG TAAGGAATGT GGAAAATTCT TCAGCTGGCG CTCTAATCTT 
ACTAGGCATC AGCTTATTCA TACTGGAGAA AAACCCTATG AGTGTAAAGA ATGTGGAAAG 
TCTTTCAGCC GGAGTTCTCA CCTCATTGGA CATCAAAAGA CCCATACTGG TGAGGAACCC 
TATGAATGTA AAGAATGTGG AAAATCCTTC AGCTGGTTCT CTCACCTTGT TACTCATCAG 
AGAACTCATA CAGGAGACAA ACTGTACACA TGTAATCAGT GTGGGAAATC TTTTGTTCAT 
AGCTCTAGGC TTATTAGACA CCAGAGGACA CATACTGGAG AGAAACCCTA TGAATGTCCT 
GAATGTGGGA AATCTTTCAG ACAGAGCACA CATCTCATTC TGCATCAGAG AACCCATGTG 
AGAGTGAGGC CCTATGAATG CAATGAATGT GGAAAGTCTT ACAGCCAGAG ATCTCACCTT 
GTTGTGCATC ATAGAATTCA CACTGGACTA AAACCTTTTG AGTGTAAGGA TTGTGGAAAA 
TGTTTTAGTC GAAGCTCTCA CCTTTATTCA CATCAAAGAA CCCACACTGG AGAGAAACCA 
TATGAGTGTC ATGATTGTGG AAAATCTTTC AGCCAGAGTT CTGCCCTTAT TGTGCATCAG 
AGGATACACA CTGGAGAGAA ACCATATGAA TGCTGTCAGT GTGGGAAAGC CTTCATCCGG 
AAGAATGACC TCATTAAGCA CCAGAGAATT CATGTTGGAG AAGAGACCTA TAAATGTAAT 
CAATGTGGCA TTATCTTCAG CCAGAACTCT CCATTTATAG TTCATCAAAT AGCTCACACT 
GGAGAGCAGT TCTTAACATG CAATCAATGT GGGACAGCGC TTGTTAATAC CTCTAACCTT 
ATTGGATACC AGACAAATCA TATTAGAGAA AATGCTTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056209.2
CDS	187..1908
Translation	MDAKSLTAWSRTLVTFKDVFVDFTREEWKLLDTAQQIVYRNVMLENYKNLVSLGYQLTKPDVILRLEKGEEPWLVEREIHQETHPDSETAFEIKSSVSSRSIFKDKQSCDIKMEGMARNDLWYLSLEEVWKCRDQLDKYQENPERHLRQVAFTQKKVLTQERVSESGKYGGNCLLPAQLVLREYFHKRDSHTKSLKHDLVLNGHQDSCASNSNECGQTFCQNIHLIQFARTHTGDKSYKCPDNDNSLTHGSSLGISKGIHREKPYECKECGKFFSWRSNLTRHQLIHTGEKPYECKECGKSFSRSSHLIGHQKTHTGEEPYECKECGKSFSWFSHLVTHQRTHTGDKLYTCNQCGKSFVHSSRLIRHQRTHTGEKPYECPECGKSFRQSTHLILHQRTHVRVRPYECNECGKSYSQRSHLVVHHRIHTGLKPFECKDCGKCFSRSSHLYSHQRTHTGEKPYECHDCGKSFSQSSALIVHQRIHTGEKPYECCQCGKAFIRKNDLIKHQRIHVGEETYKCNQCGIIFSQNSPFIVHQIAHTGEQFLTCNQCGTALVNTSNLIGYQTNHIRENAY

Target ORF information:

RefSeq Version	NM_015394.4
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 10 (ZNF10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015394.4

ORF Insert Sequence:

ATGGATGCTA AGTCACTAAC TGCCTGGTCC CGGACACTGG TGACCTTCAA GGATGTATTT 
GTGGACTTCA CCAGGGAGGA GTGGAAGCTG CTGGACACTG CTCAGCAGAT CGTGTACAGA 
AATGTGATGC TGGAGAACTA TAAGAACCTG GTTTCCTTGG GTTATCAGCT TACTAAGCCA 
GATGTGATCC TCCGGTTGGA GAAGGGAGAA GAGCCCTGGC TGGTGGAGAG AGAAATTCAC 
CAAGAGACCC ATCCTGATTC AGAGACTGCA TTTGAAATCA AATCATCAGT TTCCAGCAGG 
AGCATTTTTA AAGATAAGCA ATCCTGTGAC ATTAAAATGG AAGGAATGGC AAGGAATGAT 
CTCTGGTATT TGTCATTAGA AGAAGTCTGG AAATGTAGAG ACCAGTTAGA CAAGTATCAG 
GAAAACCCAG AGAGACATTT GAGGCAAGTG GCATTCACCC AAAAGAAAGT ACTTACTCAG 
GAGAGAGTCT CTGAAAGTGG TAAATATGGG GGAAACTGTC TTCTTCCTGC TCAGCTAGTA 
CTGAGAGAGT ATTTCCATAA ACGTGACTCA CATACTAAAA GTTTAAAACA TGATTTAGTT 
CTTAATGGTC ATCAGGACAG TTGTGCAAGT AACAGTAATG AATGTGGTCA AACTTTCTGT 
CAAAACATTC ACCTTATTCA GTTTGCAAGA ACTCACACAG GTGATAAATC CTACAAATGC 
CCTGATAATG ACAACTCTCT TACTCATGGT TCATCTCTTG GTATATCAAA GGGCATACAT 
AGAGAGAAAC CCTATGAATG TAAGGAATGT GGAAAATTCT TCAGCTGGCG CTCTAATCTT 
ACTAGGCATC AGCTTATTCA TACTGGAGAA AAACCCTATG AGTGTAAAGA ATGTGGAAAG 
TCTTTCAGCC GGAGTTCTCA CCTCATTGGA CATCAAAAGA CCCATACTGG TGAGGAACCC 
TATGAATGTA AAGAATGTGG AAAATCCTTC AGCTGGTTCT CTCACCTTGT TACTCATCAG 
AGAACTCATA CAGGAGACAA ACTGTACACA TGTAATCAGT GTGGGAAATC TTTTGTTCAT 
AGCTCTAGGC TTATTAGACA CCAGAGGACA CATACTGGAG AGAAACCCTA TGAATGTCCT 
GAATGTGGGA AATCTTTCAG ACAGAGCACA CATCTCATTC TGCATCAGAG AACCCATGTG 
AGAGTGAGGC CCTATGAATG CAATGAATGT GGAAAGTCTT ACAGCCAGAG ATCTCACCTT 
GTTGTGCATC ATAGAATTCA CACTGGACTA AAACCTTTTG AGTGTAAGGA TTGTGGAAAA 
TGTTTTAGTC GAAGCTCTCA CCTTTATTCA CATCAAAGAA CCCACACTGG AGAGAAACCA 
TATGAGTGTC ATGATTGTGG AAAATCTTTC AGCCAGAGTT CTGCCCTTAT TGTGCATCAG 
AGGATACACA CTGGAGAGAA ACCATATGAA TGCTGTCAGT GTGGGAAAGC CTTCATCCGG 
AAGAATGACC TCATTAAGCA CCAGAGAATT CATGTTGGAG AAGAGACCTA TAAATGTAAT 
CAATGTGGCA TTATCTTCAG CCAGAACTCT CCATTTATAG TTCATCAAAT AGCTCACACT 
GGAGAGCAGT TCTTAACATG CAATCAATGT GGGACAGCGC TTGTTAATAC CTCTAACCTT 
ATTGGATACC AGACAAATCA TATTAGAGAA AATGCTTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZNF10 ( NM_015394.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056209.2 Homo sapiens zinc finger protein 10 (ZNF10), mRNA.

Price & Availability↑

CloneID	OHu29577
Clone ID Related Accession (Same CDS sequence)	NM_015394.4 , NM_015394.5
Accession Version	NM_015394.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1722bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	zinc finger protein 10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC026786.5, BC024182.2, AL110188.1, BE895826.1 and AI972895.1. On Nov 22, 2018 this sequence version replaced NM_015394.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024182.2, SRR1660805.254984.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000248211.11/ ENSP00000248211.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATGCTA AGTCACTAAC TGCCTGGTCC CGGACACTGG TGACCTTCAA GGATGTATTT 
GTGGACTTCA CCAGGGAGGA GTGGAAGCTG CTGGACACTG CTCAGCAGAT CGTGTACAGA 
AATGTGATGC TGGAGAACTA TAAGAACCTG GTTTCCTTGG GTTATCAGCT TACTAAGCCA 
GATGTGATCC TCCGGTTGGA GAAGGGAGAA GAGCCCTGGC TGGTGGAGAG AGAAATTCAC 
CAAGAGACCC ATCCTGATTC AGAGACTGCA TTTGAAATCA AATCATCAGT TTCCAGCAGG 
AGCATTTTTA AAGATAAGCA ATCCTGTGAC ATTAAAATGG AAGGAATGGC AAGGAATGAT 
CTCTGGTATT TGTCATTAGA AGAAGTCTGG AAATGTAGAG ACCAGTTAGA CAAGTATCAG 
GAAAACCCAG AGAGACATTT GAGGCAAGTG GCATTCACCC AAAAGAAAGT ACTTACTCAG 
GAGAGAGTCT CTGAAAGTGG TAAATATGGG GGAAACTGTC TTCTTCCTGC TCAGCTAGTA 
CTGAGAGAGT ATTTCCATAA ACGTGACTCA CATACTAAAA GTTTAAAACA TGATTTAGTT 
CTTAATGGTC ATCAGGACAG TTGTGCAAGT AACAGTAATG AATGTGGTCA AACTTTCTGT 
CAAAACATTC ACCTTATTCA GTTTGCAAGA ACTCACACAG GTGATAAATC CTACAAATGC 
CCTGATAATG ACAACTCTCT TACTCATGGT TCATCTCTTG GTATATCAAA GGGCATACAT 
AGAGAGAAAC CCTATGAATG TAAGGAATGT GGAAAATTCT TCAGCTGGCG CTCTAATCTT 
ACTAGGCATC AGCTTATTCA TACTGGAGAA AAACCCTATG AGTGTAAAGA ATGTGGAAAG 
TCTTTCAGCC GGAGTTCTCA CCTCATTGGA CATCAAAAGA CCCATACTGG TGAGGAACCC 
TATGAATGTA AAGAATGTGG AAAATCCTTC AGCTGGTTCT CTCACCTTGT TACTCATCAG 
AGAACTCATA CAGGAGACAA ACTGTACACA TGTAATCAGT GTGGGAAATC TTTTGTTCAT 
AGCTCTAGGC TTATTAGACA CCAGAGGACA CATACTGGAG AGAAACCCTA TGAATGTCCT 
GAATGTGGGA AATCTTTCAG ACAGAGCACA CATCTCATTC TGCATCAGAG AACCCATGTG 
AGAGTGAGGC CCTATGAATG CAATGAATGT GGAAAGTCTT ACAGCCAGAG ATCTCACCTT 
GTTGTGCATC ATAGAATTCA CACTGGACTA AAACCTTTTG AGTGTAAGGA TTGTGGAAAA 
TGTTTTAGTC GAAGCTCTCA CCTTTATTCA CATCAAAGAA CCCACACTGG AGAGAAACCA 
TATGAGTGTC ATGATTGTGG AAAATCTTTC AGCCAGAGTT CTGCCCTTAT TGTGCATCAG 
AGGATACACA CTGGAGAGAA ACCATATGAA TGCTGTCAGT GTGGGAAAGC CTTCATCCGG 
AAGAATGACC TCATTAAGCA CCAGAGAATT CATGTTGGAG AAGAGACCTA TAAATGTAAT 
CAATGTGGCA TTATCTTCAG CCAGAACTCT CCATTTATAG TTCATCAAAT AGCTCACACT 
GGAGAGCAGT TCTTAACATG CAATCAATGT GGGACAGCGC TTGTTAATAC CTCTAACCTT 
ATTGGATACC AGACAAATCA TATTAGAGAA AATGCTTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056209.2
CDS	188..1909
Translation	MDAKSLTAWSRTLVTFKDVFVDFTREEWKLLDTAQQIVYRNVMLENYKNLVSLGYQLTKPDVILRLEKGEEPWLVEREIHQETHPDSETAFEIKSSVSSRSIFKDKQSCDIKMEGMARNDLWYLSLEEVWKCRDQLDKYQENPERHLRQVAFTQKKVLTQERVSESGKYGGNCLLPAQLVLREYFHKRDSHTKSLKHDLVLNGHQDSCASNSNECGQTFCQNIHLIQFARTHTGDKSYKCPDNDNSLTHGSSLGISKGIHREKPYECKECGKFFSWRSNLTRHQLIHTGEKPYECKECGKSFSRSSHLIGHQKTHTGEEPYECKECGKSFSWFSHLVTHQRTHTGDKLYTCNQCGKSFVHSSRLIRHQRTHTGEKPYECPECGKSFRQSTHLILHQRTHVRVRPYECNECGKSYSQRSHLVVHHRIHTGLKPFECKDCGKCFSRSSHLYSHQRTHTGEKPYECHDCGKSFSQSSALIVHQRIHTGEKPYECCQCGKAFIRKNDLIKHQRIHVGEETYKCNQCGIIFSQNSPFIVHQIAHTGEQFLTCNQCGTALVNTSNLIGYQTNHIRENAY

Target ORF information:

RefSeq Version	NM_015394.5
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 10 (ZNF10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015394.5

ORF Insert Sequence:

ATGGATGCTA AGTCACTAAC TGCCTGGTCC CGGACACTGG TGACCTTCAA GGATGTATTT 
GTGGACTTCA CCAGGGAGGA GTGGAAGCTG CTGGACACTG CTCAGCAGAT CGTGTACAGA 
AATGTGATGC TGGAGAACTA TAAGAACCTG GTTTCCTTGG GTTATCAGCT TACTAAGCCA 
GATGTGATCC TCCGGTTGGA GAAGGGAGAA GAGCCCTGGC TGGTGGAGAG AGAAATTCAC 
CAAGAGACCC ATCCTGATTC AGAGACTGCA TTTGAAATCA AATCATCAGT TTCCAGCAGG 
AGCATTTTTA AAGATAAGCA ATCCTGTGAC ATTAAAATGG AAGGAATGGC AAGGAATGAT 
CTCTGGTATT TGTCATTAGA AGAAGTCTGG AAATGTAGAG ACCAGTTAGA CAAGTATCAG 
GAAAACCCAG AGAGACATTT GAGGCAAGTG GCATTCACCC AAAAGAAAGT ACTTACTCAG 
GAGAGAGTCT CTGAAAGTGG TAAATATGGG GGAAACTGTC TTCTTCCTGC TCAGCTAGTA 
CTGAGAGAGT ATTTCCATAA ACGTGACTCA CATACTAAAA GTTTAAAACA TGATTTAGTT 
CTTAATGGTC ATCAGGACAG TTGTGCAAGT AACAGTAATG AATGTGGTCA AACTTTCTGT 
CAAAACATTC ACCTTATTCA GTTTGCAAGA ACTCACACAG GTGATAAATC CTACAAATGC 
CCTGATAATG ACAACTCTCT TACTCATGGT TCATCTCTTG GTATATCAAA GGGCATACAT 
AGAGAGAAAC CCTATGAATG TAAGGAATGT GGAAAATTCT TCAGCTGGCG CTCTAATCTT 
ACTAGGCATC AGCTTATTCA TACTGGAGAA AAACCCTATG AGTGTAAAGA ATGTGGAAAG 
TCTTTCAGCC GGAGTTCTCA CCTCATTGGA CATCAAAAGA CCCATACTGG TGAGGAACCC 
TATGAATGTA AAGAATGTGG AAAATCCTTC AGCTGGTTCT CTCACCTTGT TACTCATCAG 
AGAACTCATA CAGGAGACAA ACTGTACACA TGTAATCAGT GTGGGAAATC TTTTGTTCAT 
AGCTCTAGGC TTATTAGACA CCAGAGGACA CATACTGGAG AGAAACCCTA TGAATGTCCT 
GAATGTGGGA AATCTTTCAG ACAGAGCACA CATCTCATTC TGCATCAGAG AACCCATGTG 
AGAGTGAGGC CCTATGAATG CAATGAATGT GGAAAGTCTT ACAGCCAGAG ATCTCACCTT 
GTTGTGCATC ATAGAATTCA CACTGGACTA AAACCTTTTG AGTGTAAGGA TTGTGGAAAA 
TGTTTTAGTC GAAGCTCTCA CCTTTATTCA CATCAAAGAA CCCACACTGG AGAGAAACCA 
TATGAGTGTC ATGATTGTGG AAAATCTTTC AGCCAGAGTT CTGCCCTTAT TGTGCATCAG 
AGGATACACA CTGGAGAGAA ACCATATGAA TGCTGTCAGT GTGGGAAAGC CTTCATCCGG 
AAGAATGACC TCATTAAGCA CCAGAGAATT CATGTTGGAG AAGAGACCTA TAAATGTAAT 
CAATGTGGCA TTATCTTCAG CCAGAACTCT CCATTTATAG TTCATCAAAT AGCTCACACT 
GGAGAGCAGT TCTTAACATG CAATCAATGT GGGACAGCGC TTGTTAATAC CTCTAACCTT 
ATTGGATACC AGACAAATCA TATTAGAGAA AATGCTTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZNF10 inhibits HIV-1 LTR activity through interaction with NF-?B and Sp1 binding motifs.
FEBS letters589(15)2019-25(2015 Jul)
Nishitsuji H,Sawada L,Sugiyama R,Takaku H

The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1.
PloS one9(2)e87609(2014)
Born N,Thiesen HJ,Lorenz P

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.
Cellular and molecular life sciences : CMLS70(20)3947-58(2013 Oct)
Wang W,Cai J,Wu Y,Hu L,Chen Z,Hu J,Chen Z,Li W,Guo M,Huang Z

Transcriptional repression mediated by the KRAB domain of the human C2H2 zinc finger protein Kox1/ZNF10 does not require histone deacetylation.
Biological chemistry382(4)637-44(2001 Apr)
Lorenz P,Koczan D,Thiesen HJ

Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain.
The Journal of biological chemistry275(24)18000-10(2000 Jun)
Peng H,Begg GE,Harper SL,Friedman JR,Speicher DW,Rauscher FJ 3rd

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ZNF10 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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