Gene Symbol | USF1 |
Entrez Gene ID | 7391 |
Full Name | upstream transcription factor 1 |
Synonyms | FCHL,FCHL1,HYPLIP1,MLTF,MLTFI,UEF,bHLHb11 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013]. |
Disorder MIM: | |
Disorder Html: | {Hyperlipidemia, familial combined, susceptibility to}, 602491 (3) |