Gene Symbol | UGT2B17 |
Entrez Gene ID | 7367 |
Full Name | UDP glucuronosyltransferase family 2 member B17 |
Synonyms | BMND12,UDPGT2B17 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]. |
Disorder MIM: | |
Disorder Html: | {Bone mineral density QTL 12, osteoporosis}, 612560 (3) |