UCHL3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UCHL3
Entrez Gene ID	7347
Full Name	ubiquitin C-terminal hydrolase L3
Synonyms	UCH-L3
General protein information	Preferred Names ubiquitin C-terminal hydrolase L3 Names ubiquitin carboxyl-terminal hydrolase isozyme L3 testicular tissue protein Li 221 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) ubiquitin thioesterase L3 ubiquitin thiolesterase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q22.2
Summary	The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].
Disorder MIM:	603090

mRNA and Protein(s)

mRNA	Protein	Name
XM_011535214.2	XP_011533516.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X4
XM_017020726.1	XP_016876215.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X5
NM_006002.4	NP_005993.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 2
XM_017020725.1	XP_016876214.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X3
XM_017020727.1	XP_016876216.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X6
XM_011535213.2	XP_011533515.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X2
XM_011535212.1	XP_011533514.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1
NM_001270952.1	NP_001257881.1	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	UCHL3	NP_990156.1
Drosophila melanogaster (fruit fly)	Uch	NP_001188681.1
Saccharomyces cerevisiae (baker's yeast)	YUH1	NP_012633.1
Canis lupus familiaris (dog)	UCHL3	XP_534147.3
Pan troglodytes (chimpanzee)	UCHL3	XP_003314228.1
Bos taurus (cattle)	UCHL3	NP_001035631.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012113	XP_320415.2
Kluyveromyces lactis	KLLA0E09967g	XP_454399.1
Eremothecium gossypii	AGOS_AGL314C	NP_986353.1
Oryza sativa (rice)	Os02g0654500	NP_001047612.1
Homo sapiens (human)	UCHL3	NP_005993.1
Neurospora crassa	NCU06372	XP_962406.1
	UCHL3	XP_001085879.2
Mus musculus (house mouse)	Uchl3	NP_057932.2
Rattus norvegicus (Norway rat)	Uchl3	NP_001103635.1
Danio rerio (zebrafish)	uchl3	NP_001019576.1
Magnaporthe oryzae (rice blast fungus)	MGG_01683	XP_003714672.1
Arabidopsis thaliana (thale cress)	UCH3	NP_193484.1
Xenopus tropicalis (tropical clawed frog)	uchl3	NP_001017120.1

Gene Ontology
Bibliography

Related articles in PubMed

Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Zhao P, Guo T, Qian L, Wang X, Yuan Y, Cheng Q, Zuo Y, Liu J, Miao Y, Feng Q, Zhang L, Wu S, Zheng H
Antiviral research144120-129(2017 Aug)

Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3.
Nam MJ, Madoz-Gurpide J, Wang H, Lescure P, Schmalbach CE, Zhao R, Misek DE, Kuick R, Brenner DE, Hanash SM
Proteomics3(11)2108-15(2003 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study demonstrated positive correlations between the level and activity of UCHL3 and sperm characteristics and function suggesting that UCHL3 may play a role in male infertility.
Title: Ubiquitin Carboxy-Terminal HydrolaseL3 Correlates with Human Sperm Count, Motility and Fertilization.

Using a series of engineered protein substrates, which are similar in size yet differ in secondary structure, we demonstrate that thermal stability is a key factor that significantly affects UCH-L3 hydrolysis.
Title: Characterizing substrate selectivity of ubiquitin C-terminal hydrolase-L3 using engineered ?-linked ubiquitin substrates.

UCH-L3 is a novel regulator of epithelial-mesenchymal transition and cell migration in prostate cancer cells.
Title: Ubiquitin C-terminal hydrolase-L3 regulates EMT process and cancer metastasis in prostate cell lines.

Data identified of UCHL3 as an essential deubiquitinase in adipogenesis.
Title: A novel RNAi lethality rescue screen to identify regulators of adipogenesis.

impaired UCH-L3 function may contribute to the accumulation of full length UBB(+1) in various pathologie
Title: Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3).

The following UCHL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UCHL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10261	NM_001270952.1 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu56052	NM_006002.4 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu61217	XM_011535212.1 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu61218	XM_011535213.2 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu61219	XM_011535214.2 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu84626	XM_017020725.1 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu84627	XM_017020726.1 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu84628	XM_017020727.1 Latest version!	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UCHL3 ( NM_001270952.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257881.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10261
Clone ID Related Accession (Same CDS sequence)	NM_001270952.1
Accession Version	NM_001270952.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137244.28, BQ427804.1, BC018125.2 and AA234624.1. Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU945230.1, SRR1163655.255477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATCCTG AACTCCTTAG CATGGTACCA AGACCAGTCT GTGCAGTCTT ACTTCTCTTT 
CCTATTACAG AAAAGTATGA AGTATTCAGA ACAGAAGAGG AAGAAAAAAT AAAATCTCAG 
GGACAAGATG TTACATCATC AGTATATTTC ATGAAGCAAA CAATCAGCAA TGCCTGTGGA 
ACAATTGGAC TGATTCATGC TATTGCAAAC AATAAAGACA AGATGCACTT TGAATCTGGA 
TCAACCTTGA AAAAATTCCT GGAGGAATCT GTGTCAATGA GCCCTGAAGA ACGAGCCAGA 
TACCTGGAGA ACTATGATGC CATCCGAGTT ACTCATGAGA CCAGTGCCCA TGAAGGTCAG 
ACTGAGGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGATGGGCGG AAGCCATTTC CAATTAACCA TGGTGAAACT 
AGTGATGAAA CTTTATTAGA GGATGCCATA GAAGTTTGCA AGAAGTTTAT GGAGCGCGAC 
CCTGATGAAC TAAGATTTAA TGCGATTGCT CTTTCTGCAG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257881.1
CDS	258..842
Translation	MDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	NM_001270952.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270952.1

ORF Insert Sequence:

ATGGATCCTG AACTCCTTAG CATGGTACCA AGACCAGTCT GTGCAGTCTT ACTTCTCTTT 
CCTATTACAG AAAAGTATGA AGTATTCAGA ACAGAAGAGG AAGAAAAAAT AAAATCTCAG 
GGACAAGATG TTACATCATC AGTATATTTC ATGAAGCAAA CAATCAGCAA TGCCTGTGGA 
ACAATTGGAC TGATTCATGC TATTGCAAAC AATAAAGACA AGATGCACTT TGAATCTGGA 
TCAACCTTGA AAAAATTCCT GGAGGAATCT GTGTCAATGA GCCCTGAAGA ACGAGCCAGA 
TACCTGGAGA ACTATGATGC CATCCGAGTT ACTCATGAGA CCAGTGCCCA TGAAGGTCAG 
ACTGAGGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGATGGGCGG AAGCCATTTC CAATTAACCA TGGTGAAACT 
AGTGATGAAA CTTTATTAGA GGATGCCATA GAAGTTTGCA AGAAGTTTAT GGAGCGCGAC 
CCTGATGAAC TAAGATTTAA TGCGATTGCT CTTTCTGCAG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( NM_006002.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005993.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu56052
Clone ID Related Accession (Same CDS sequence)	NM_006002.4
Accession Version	NM_006002.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA820150.1, BC018125.2 and AA234624.1. On Aug 18, 2012 this sequence version replaced NM_006002.3. Transcript Variant: This variant (2) contains an alternate exon in the 5' coding region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.83456.1, SRR1803611.84706.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGGCACCA 
AGTATAGATG AGAAAGTAGA TCTTCATTTT ATTGCATTAG TTCATGTAGA TGGGCATCTC 
TATGAATTAG ATGGGCGGAA GCCATTTCCA ATTAACCATG GTGAAACTAG TGATGAAACT 
TTATTAGAGG ATGCCATAGA AGTTTGCAAG AAGTTTATGG AGCGCGACCC TGATGAACTA 
AGATTTAATG CGATTGCTCT TTCTGCAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005993.1
CDS	72..764
Translation	MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	NM_006002.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006002.4

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGGCACCA 
AGTATAGATG AGAAAGTAGA TCTTCATTTT ATTGCATTAG TTCATGTAGA TGGGCATCTC 
TATGAATTAG ATGGGCGGAA GCCATTTCCA ATTAACCATG GTGAAACTAG TGATGAAACT 
TTATTAGAGG ATGCCATAGA AGTTTGCAAG AAGTTTATGG AGCGCGACCC TGATGAACTA 
AGATTTAATG CGATTGCTCT TTCTGCAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_011535212.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533514.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61217
Clone ID Related Accession (Same CDS sequence)	XM_011535212.1
Accession Version	XM_011535212.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 885bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGATGGGCGG AAGCCATTTC CAATTAACCA TGGTGAAACT 
AGTGATGAAA CTTTATTAGA GGATGCCATA GAAGTTTGCA AGAAGTTTAT GGAGCGCGAC 
CCTGATGAAC TAAGATTTAA TGCGATTGCT CTTTCTGCAG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533514.1
CDS	72..956
Translation	MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	XM_011535212.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535212.1

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGATGGGCGG AAGCCATTTC CAATTAACCA TGGTGAAACT 
AGTGATGAAA CTTTATTAGA GGATGCCATA GAAGTTTGCA AGAAGTTTAT GGAGCGCGAC 
CCTGATGAAC TAAGATTTAA TGCGATTGCT CTTTCTGCAG CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_011535213.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533515.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61218
Clone ID Related Accession (Same CDS sequence)	XM_011535213.2
Accession Version	XM_011535213.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535213.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGTTTCTTAA ACAATTAGGT 
CTACATCCTA ACTGGCAATT CGTTGATGTA TATGGAATGG ATCCTGAACT CCTTAGCATG 
GTACCAAGAC CAGTCTGTGC AGTCTTACTT CTCTTTCCTA TTACAGAAAA GTATGAAGTA 
TTCAGAACAG AAGAGGAAGA AAAAATAAAA TCTCAGGGAC AAGATGTTAC ATCATCAGTA 
TATTTCATGA AGCAAACAAT CAGCAATGCC TGTGGAACAA TTGGACTGAT TCATGCTATT 
GCAAACAATA AAGACAAGAT GCACTTTGAA TCTGGATCAA CCTTGAAAAA ATTCCTGGAG 
GAATCTGTGT CAATGAGCCC TGAAGAACGA GCCAGATACC TGGAGAACTA TGATGCCATC 
CGAGTTACTC ATGAGACCAG TGCCCATGAA GGTCAGACTG AGTCCTCCTC GCCATCCTCA 
TCACAGCCTC ATTCTAGCCA CTGCAGAACG AAGGCCTCAT CATTGTGTCA CCATGCATCC 
CTGCCCTGGG TCAAACGTAA CCATGTAGGC CCTGCAAAGG CTACCAGTCC ATCTCTCCGT 
CTTCGTCGCT GGCGACCCTT CTTACGTCTA CCATCTTTGG GTCTCCATTC TGTTGCACCA 
AGTATAGATG AGAAAGTAGA TCTTCATTTT ATTGCATTAG TTCATGTAGA TGGGCATCTC 
TATGAATTAG ATGGGCGGAA GCCATTTCCA ATTAACCATG GTGAAACTAG TGATGAAACT 
TTATTAGAGG ATGCCATAGA AGTTTGCAAG AAGTTTATGG AGCGCGACCC TGATGAACTA 
AGATTTAATG CGATTGCTCT TTCTGCAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533515.1
CDS	65..937
Translation	MEGQRWLPLEANPEFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	XM_011535213.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535213.2

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGTTTCTTAA ACAATTAGGT 
CTACATCCTA ACTGGCAATT CGTTGATGTA TATGGAATGG ATCCTGAACT CCTTAGCATG 
GTACCAAGAC CAGTCTGTGC AGTCTTACTT CTCTTTCCTA TTACAGAAAA GTATGAAGTA 
TTCAGAACAG AAGAGGAAGA AAAAATAAAA TCTCAGGGAC AAGATGTTAC ATCATCAGTA 
TATTTCATGA AGCAAACAAT CAGCAATGCC TGTGGAACAA TTGGACTGAT TCATGCTATT 
GCAAACAATA AAGACAAGAT GCACTTTGAA TCTGGATCAA CCTTGAAAAA ATTCCTGGAG 
GAATCTGTGT CAATGAGCCC TGAAGAACGA GCCAGATACC TGGAGAACTA TGATGCCATC 
CGAGTTACTC ATGAGACCAG TGCCCATGAA GGTCAGACTG AGTCCTCCTC GCCATCCTCA 
TCACAGCCTC ATTCTAGCCA CTGCAGAACG AAGGCCTCAT CATTGTGTCA CCATGCATCC 
CTGCCCTGGG TCAAACGTAA CCATGTAGGC CCTGCAAAGG CTACCAGTCC ATCTCTCCGT 
CTTCGTCGCT GGCGACCCTT CTTACGTCTA CCATCTTTGG GTCTCCATTC TGTTGCACCA 
AGTATAGATG AGAAAGTAGA TCTTCATTTT ATTGCATTAG TTCATGTAGA TGGGCATCTC 
TATGAATTAG ATGGGCGGAA GCCATTTCCA ATTAACCATG GTGAAACTAG TGATGAAACT 
TTATTAGAGG ATGCCATAGA AGTTTGCAAG AAGTTTATGG AGCGCGACCC TGATGAACTA 
AGATTTAATG CGATTGCTCT TTCTGCAGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_011535214.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533516.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X4, mRNA.

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CloneID	OHu61219
Clone ID Related Accession (Same CDS sequence)	XM_011535214.2
Accession Version	XM_011535214.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535214.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCCTG AACTCCTTAG CATGGTACCA AGACCAGTCT GTGCAGTCTT ACTTCTCTTT 
CCTATTACAG AAAAGTATGA AGTATTCAGA ACAGAAGAGG AAGAAAAAAT AAAATCTCAG 
GGACAAGATG TTACATCATC AGTATATTTC ATGAAGCAAA CAATCAGCAA TGCCTGTGGA 
ACAATTGGAC TGATTCATGC TATTGCAAAC AATAAAGACA AGATGCACTT TGAATCTGGA 
TCAACCTTGA AAAAATTCCT GGAGGAATCT GTGTCAATGA GCCCTGAAGA ACGAGCCAGA 
TACCTGGAGA ACTATGATGC CATCCGAGTT ACTCATGAGA CCAGTGCCCA TGAAGGTCAG 
ACTGAGTCCT CCTCGCCATC CTCATCACAG CCTCATTCTA GCCACTGCAG AACGAAGGCC 
TCATCATTGT GTCACCATGC ATCCCTGCCC TGGGTCAAAC GTAACCATGT AGGCCCTGCA 
AAGGCTACCA GTCCATCTCT CCGTCTTCGT CGCTGGCGAC CCTTCTTACG TCTACCATCT 
TTGGGTCTCC ATTCTGTTGC ACCAAGTATA GATGAGAAAG TAGATCTTCA TTTTATTGCA 
TTAGTTCATG TAGATGGGCA TCTCTATGAA TTAGATGGGC GGAAGCCATT TCCAATTAAC 
CATGGTGAAA CTAGTGATGA AACTTTATTA GAGGATGCCA TAGAAGTTTG CAAGAAGTTT 
ATGGAGCGCG ACCCTGATGA ACTAAGATTT AATGCGATTG CTCTTTCTGC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533516.1
CDS	248..1024
Translation	MDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	XM_011535214.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535214.2

ORF Insert Sequence:

ATGGATCCTG AACTCCTTAG CATGGTACCA AGACCAGTCT GTGCAGTCTT ACTTCTCTTT 
CCTATTACAG AAAAGTATGA AGTATTCAGA ACAGAAGAGG AAGAAAAAAT AAAATCTCAG 
GGACAAGATG TTACATCATC AGTATATTTC ATGAAGCAAA CAATCAGCAA TGCCTGTGGA 
ACAATTGGAC TGATTCATGC TATTGCAAAC AATAAAGACA AGATGCACTT TGAATCTGGA 
TCAACCTTGA AAAAATTCCT GGAGGAATCT GTGTCAATGA GCCCTGAAGA ACGAGCCAGA 
TACCTGGAGA ACTATGATGC CATCCGAGTT ACTCATGAGA CCAGTGCCCA TGAAGGTCAG 
ACTGAGTCCT CCTCGCCATC CTCATCACAG CCTCATTCTA GCCACTGCAG AACGAAGGCC 
TCATCATTGT GTCACCATGC ATCCCTGCCC TGGGTCAAAC GTAACCATGT AGGCCCTGCA 
AAGGCTACCA GTCCATCTCT CCGTCTTCGT CGCTGGCGAC CCTTCTTACG TCTACCATCT 
TTGGGTCTCC ATTCTGTTGC ACCAAGTATA GATGAGAAAG TAGATCTTCA TTTTATTGCA 
TTAGTTCATG TAGATGGGCA TCTCTATGAA TTAGATGGGC GGAAGCCATT TCCAATTAAC 
CATGGTGAAA CTAGTGATGA AACTTTATTA GAGGATGCCA TAGAAGTTTG CAAGAAGTTT 
ATGGAGCGCG ACCCTGATGA ACTAAGATTT AATGCGATTG CTCTTTCTGC AGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_017020725.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876214.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X3, mRNA.

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CloneID	OHu84626
Clone ID Related Accession (Same CDS sequence)	XM_017020725.1
Accession Version	XM_017020725.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGGAAATTTC CACAGCCACC CCAATCTTCA GCAACCGCCG 
TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876214.1
CDS	72..857
Translation	MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELGNFHSHPNLQQPPS

Target ORF information:

RefSeq Version	XM_017020725.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020725.1

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGGAAATTTC CACAGCCACC CCAATCTTCA GCAACCGCCG 
TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_017020726.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876215.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu84627
Clone ID Related Accession (Same CDS sequence)	XM_017020726.1
Accession Version	XM_017020726.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGACCTTCTC GAGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876215.1
CDS	72..830
Translation	MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDLLEF

Target ORF information:

RefSeq Version	XM_017020726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020726.1

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGGTCACCAA CCAGTTTCTT 
AAACAATTAG GTCTACATCC TAACTGGCAA TTCGTTGATG TATATGGAAT GGATCCTGAA 
CTCCTTAGCA TGGTACCAAG ACCAGTCTGT GCAGTCTTAC TTCTCTTTCC TATTACAGAA 
AAGTATGAAG TATTCAGAAC AGAAGAGGAA GAAAAAATAA AATCTCAGGG ACAAGATGTT 
ACATCATCAG TATATTTCAT GAAGCAAACA ATCAGCAATG CCTGTGGAAC AATTGGACTG 
ATTCATGCTA TTGCAAACAA TAAAGACAAG ATGCACTTTG AATCTGGATC AACCTTGAAA 
AAATTCCTGG AGGAATCTGT GTCAATGAGC CCTGAAGAAC GAGCCAGATA CCTGGAGAAC 
TATGATGCCA TCCGAGTTAC TCATGAGACC AGTGCCCATG AAGGTCAGAC TGAGTCCTCC 
TCGCCATCCT CATCACAGCC TCATTCTAGC CACTGCAGAA CGAAGGCCTC ATCATTGTGT 
CACCATGCAT CCCTGCCCTG GGTCAAACGT AACCATGTAG GCCCTGCAAA GGCTACCAGT 
CCATCTCTCC GTCTTCGTCG CTGGCGACCC TTCTTACGTC TACCATCTTT GGGTCTCCAT 
TCTGTTGCAC CAAGTATAGA TGAGAAAGTA GATCTTCATT TTATTGCATT AGTTCATGTA 
GATGGGCATC TCTATGAATT AGACCTTCTC GAGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UCHL3 ( XM_017020727.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876216.1 Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu84628
Clone ID Related Accession (Same CDS sequence)	XM_017020727.1
Accession Version	XM_017020727.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGTTTCTTAA ACAATTAGGT 
CTACATCCTA ACTGGCAATT CGTTGATGTA TATGGAATGG ATCCTGAACT CCTTAGCATG 
GTACCAAGAC CAGTCTGTGC AGTCTTACTT CTCTTTCCTA TTACAGAAAA GTATGAAGTA 
TTCAGAACAG AAGAGGAAGA AAAAATAAAA TCTCAGGGAC AAGATGTTAC ATCATCAGTA 
TATTTCATGA AGCAAACAAT CAGCAATGCC TGTGGAACAA TTGGACTGAT TCATGCTATT 
GCAAACAATA AAGACAAGAT GCACTTTGAA TCTGGATCAA CCTTGAAAAA ATTCCTGGAG 
GAATCTGTGT CAATGAGCCC TGAAGAACGA GCCAGATACC TGGAGAACTA TGATGCCATC 
CGAGTTACTC ATGAGACCAG TGCCCATGAA GGTCAGACTG AGGCACCAAG TATAGATGAG 
AAAGTAGATC TTCATTTTAT TGCATTAGTT CATGTAGATG GGCATCTCTA TGAATTAGAT 
GGGCGGAAGC CATTTCCAAT TAACCATGGT GAAACTAGTG ATGAAACTTT ATTAGAGGAT 
GCCATAGAAG TTTGCAAGAA GTTTATGGAG CGCGACCCTG ATGAACTAAG ATTTAATGCG 
ATTGCTCTTT CTGCAGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876216.1
CDS	59..739
Translation	MEGQRWLPLEANPEFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

Target ORF information:

RefSeq Version	XM_017020727.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin C-terminal hydrolase L3 (UCHL3), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020727.1

ORF Insert Sequence:

ATGGAGGGTC AACGCTGGCT GCCGCTGGAG GCCAATCCCG AGTTTCTTAA ACAATTAGGT 
CTACATCCTA ACTGGCAATT CGTTGATGTA TATGGAATGG ATCCTGAACT CCTTAGCATG 
GTACCAAGAC CAGTCTGTGC AGTCTTACTT CTCTTTCCTA TTACAGAAAA GTATGAAGTA 
TTCAGAACAG AAGAGGAAGA AAAAATAAAA TCTCAGGGAC AAGATGTTAC ATCATCAGTA 
TATTTCATGA AGCAAACAAT CAGCAATGCC TGTGGAACAA TTGGACTGAT TCATGCTATT 
GCAAACAATA AAGACAAGAT GCACTTTGAA TCTGGATCAA CCTTGAAAAA ATTCCTGGAG 
GAATCTGTGT CAATGAGCCC TGAAGAACGA GCCAGATACC TGGAGAACTA TGATGCCATC 
CGAGTTACTC ATGAGACCAG TGCCCATGAA GGTCAGACTG AGGCACCAAG TATAGATGAG 
AAAGTAGATC TTCATTTTAT TGCATTAGTT CATGTAGATG GGCATCTCTA TGAATTAGAT 
GGGCGGAAGC CATTTCCAAT TAACCATGGT GAAACTAGTG ATGAAACTTT ATTAGAGGAT 
GCCATAGAAG TTTGCAAGAA GTTTATGGAG CGCGACCCTG ATGAACTAAG ATTTAATGCG 
ATTGCTCTTT CTGCAGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ubiquitin C-terminal hydrolase-L3 promotes interferon antiviral activity by stabilizing type I-interferon receptor.
Antiviral research144120-129(2017 Aug)
Zhao P,Guo T,Qian L,Wang X,Yuan Y,Cheng Q,Zuo Y,Liu J,Miao Y,Feng Q,Zhang L,Wu S,Zheng H

Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3.
Proteomics3(11)2108-15(2003 Nov)
Nam MJ,Madoz-Gurpide J,Wang H,Lescure P,Schmalbach CE,Zhao R,Misek DE,Kuick R,Brenner DE,Hanash SM

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UCHL3 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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