NBPF8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NBPF8
Entrez Gene ID	728841
Full Name	NBPF member 8
Synonyms	NBPF8P
General protein information	Preferred Names NBPF member 8 Names putative neuroblastoma breakpoint family member 8 neuroblastoma breakpoint family member 8 neuroblastoma breakpoint family, member 8, pseudogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p11.2
Summary	This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013].
Disorder MIM:	613998

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037501.2	NP_001032590.2	putative neuroblastoma breakpoint family member 8
NM_001037501.3	NP_001032590.2	putative neuroblastoma breakpoint family member 8

Pathways from BioSystems

Homologies

Homo sapiens (human)	NBPF11	NP_899228.4
Homo sapiens (human)	LOC102724250	XP_006724955.1
Homo sapiens (human)	NBPF14	NP_056198.2
Homo sapiens (human)	NBPF10	NP_001034792.4
Homo sapiens (human)	NBPF20	NP_001265196.1
Homo sapiens (human)	NBPF12	NP_001265070.1
Homo sapiens (human)	NBPF9	NP_001032764.2
Homo sapiens (human)	NBPF26	XP_005277561.1
Homo sapiens (human)	NBPF15	NP_001164226.1
Homo sapiens (human)	NBPF19	XP_005277530.1
Pan troglodytes (chimpanzee)	LOC458021	XP_003954190.1
Homo sapiens (human)	NBPF8	NP_001032590.2
Homo sapiens (human)	NBPF1	NP_060410.2

Gene Ontology
Bibliography

Related articles in PubMed

DUF1220-domain copy number implicated in human brain-size pathology and evolution.
Dumas LJ, O'Bleness MS, Davis JM, Dickens CM, Anderson N, Keeney JG, Jackson J, Sikela M, Raznahan A, Giedd J, Rapoport J, Nagamani SS, Erez A, Brunetti-Pierri N, Sugalski R, Lupski JR, Fingerlin T, Cheung SW, Sikela JM
American journal of human genetics91(3)444-54(2012 Sep)

Evolutionary history and genome organization of DUF1220 protein domains.
O'Bleness MS, Dickens CM, Dumas LJ, Kehrer-Sawatzki H, Wyckoff GJ, Sikela JM
G3 (Bethesda, Md.)2(9)977-86(2012 Sep)

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.
Vandepoele K, Van Roy N, Staes K, Speleman F, van Roy F
Molecular biology and evolution22(11)2265-74(2005 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NBPF8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NBPF8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14447	NM_001037501.3 Latest version!	Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
View Old Accession Versions >>
OHu14447	NM_001037501.2	Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NBPF8 ( NM_001037501.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032590.2 Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14447
Clone ID Related Accession (Same CDS sequence)	NM_001037501.2 , NM_001037501.3
Accession Version	NM_001037501.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2829bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-03-03
Organism	Homo sapiens(Human)
Product	putative neuroblastoma breakpoint family member 8
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC241952.2. On or before Apr 5, 2013 this sequence version replaced XR_110613.3, XR_171189.1, XR_159151.1, XR_171240.1, NM_001037501.1. Transcript Variant: This variant (1) represents the longest transcript. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC086308.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGTAT CAGCCGGCCC TTGGTCCAGC GAGAAGGCAG AGATGAACAT TCTAGAAATC 
AACGAGAAAT TGCGCCCCCA GTTGGCAGAG AACAAACAGC AGTTCGTAAA CCTCAAAGAG 
AGATGTTTTC TAACTCAACT GGCCGGCTTC CTGGCCAACC GACAGAAGAA ATACAAGTAT 
GAAGAGTGTA AAGACCTCAT AAGATTTATG CTGAGGAATG AGCGACAGTT CAAGGAGGAG 
AAGCTTGCAG AGCAGCTCAA GCAAGCTGAG GAGCTCAGGC AATATAAAGT CCTGGTTCAC 
TCTCAGGAAC GAGAGCTGAC GCAGTTAAAG GAGAAGTTAC AGGAAGGGAG AGATGCCTCC 
CGCTCATTGA ATGAGCATCT CCAGGCCCTC CTCACTCTGG ATGAGCCGGA CAAGTCCCAG 
GGGCAGGACC TCCAAGAACA GCTGGCTGAG GGGTGTAGAC TGGCACAGCA CCTTGTCCAA 
AAGCTCAGCC CAGAAAATGA CGAAGATGAG GATGAAGATG TTCAAGTTGA GGAGGATGAG 
AAAGTGCAGA AATCATCTGC CCCCAGGGAG GTGCAGAAGG CTGAAGAGAG CAAAGTCCCT 
GAGGACTCAC TGGAGGAATG TGCCATCACT TGTTCAAATA GCCACGGCCC TTGTGACTCC 
AACCAGCCTC ACAAGAACAT CAAAATCACA TTTGAGGAAG ACGAAGTCAA CTCAACTCTG 
GTTGTAGACA GAGAATCCTC TCATGATGAA TGTCAGGATG CTCTAAACAT TCTCTCAGTC 
CCTGGCCCCA CCTCTTCTGC CACAAACGTC AGCATGGTGG TATCAGCCGG CCCTTTGTCC 
AGCGAGAAGG CAGAGATGAA CATTCTAGAA ATCAATGAGA AATTGCACCC CCAGCTGGCA 
GAGAAGAAAC AGCAGTTCAG AAACCTCAAA GAGAAATGTT TTCTAACTCA ACTGGCCGGC 
TTCCTGGCCA ACCGACAGAA CAAATACAAA TATGAAGAGT GCAAAGATCT CATAAAATCT 
ATGCTGAGGA ATGAGCGACA GTTCAAGGAG GAGAAGCTTG CAGAGCAGCT CAAGCAAGCT 
GAGGAGCTCA GGCAATATAA AGTCCTGGTT CACACTCAGG AACGAGAGCT GACCCAGTTA 
AGGGAGAAGT TGCGGGAAGG GAGAGATGCC TCCCTCTCAT TGAATGAGCA TCTCCAGGCC 
CTCCTCACTC CGGATGAGCC GGACAAGTCC CAGGGGCAGG ACCTCCAAGA ACAGCTGGCT 
GAGGGGTGTA GACTGGCACA GCACCTTGTC CAAAAGCTCA GCCCAGAAAA TGACAACGAT 
GACGATGAAG ATGTTCAAGT TGAGGTGGCT GAGAAAGTGC AGAAATCGTC TGCCCCCAGG 
GAGATGCAGA AGGCTGAAGA AAAGGAAGTC CCTGAGGACT CACTGGAGGA ATGTGCCATC 
ACTTATTCAA ATAGCCATGG CCCTTATGAC TCCAACCAGC CACATAGGAA AACCAAAATC 
ACATTTGAGG AAGACAAAGT CGACTCAGCT CTCATTGGCT CATCCTCTCA TGTTGAATGG 
GAGGATGCTG TACACATTAT TCCAGAAAAT GAAAGTGATG ATGAGGAAGA GGAAGAAAAA 
GGACCAGTGT CTCCCAGGAA TCTGCAGGAG TCTGAAGAGG AGGAAGTCCC CCAGGAGTCC 
TGGGATGAAG GTTATTCGAC TCTCTCAATT CCTCCTGAAA TGTTGGCCTC GTACAAGTCT 
TACAGCAGCA CATTTCACTC ATTAGAGGAA CAGCAAGTCT GCATGGCTGT TGACATAGGC 
AGACATCGGT GGGATCAAGT GAAAAAGGAG GACCAAGAGG CAACAGGTCC CAGGCTCAGC 
AGGGAGCTGC TGGATGAGAA AGGGCCTGAA GTCTTGCAGG ACTCACTGGA TAGATGTTAT 
TCAACTCCTT CAGGTTGCCT TGAACTGACT GACTCATGCC AGCCCTACAG AAGTGCGTTT 
TACATATTGG AGCAACAGCG TGTTGGCTTG GCTGTTGACA TGGATGAAAT TGAAAAGTAC 
CAAGAAGTGG AAGAAGACCA AGACCCATCA TGCCCCAGGC TCAGCAGGGA GCTGCTGGAT 
GAGAAAGAGC CTGAAGTCTT GCAGGACTCA CTGGATAGAT GTTATTCGAC TCCTTCAGGT 
TATCTTGAAC TGCCTGACTT AGGCCAGCCC TACAGCAGTG CTGTTTACTC ATTGGAGGAA 
CAGTACCTTG GCTTGGCTCT TGACGTGGAC AGAATTAAAA AGGACCAAGA AGAGGAAGAA 
GACCAAGGCC CACCATGCCC CAGGCTCAGC AGGGAGCTGC TGGAGGTAGT AGAGCCTGAA 
GTCTTGCAGG ACTCACTGGA TAGATGTTAT TCAACTCCTT CCAGTTGTCT TGAACAGCCT 
GACTCCTGCC AGCCGTATGG AAGTTCCTTT TATGCATTGG AGGAAAAACA TGTTGGCTTT 
TCTCTTGACG TGGGAGAAAT TGAAAAGAAG GGGAAGGGGA AGATAAGAAG GGGAAGAAGA 
TCAAAGAAGA AAAGAAGAAG GGGAAGAAAA GAAGGGGAAG AAGATCAAAA CCCACCATGC 
CCCAGGCTCA ACAGCGTGCT GATGGAAGTG GAAGAGCCTG AAGTCTTACA GGACTCACTG 
GATAGATGTT ATTCGACTCC ATCAATGTAC TGTGAACTAC GTGACTCATT CCAGCACTAC 
AGAAGTGTGT TTTACTCATT TGAGGAACAG CACATCAGCT TTGCCCTTGA CATGGACAAT 
AGGTTCTTTA CTTTGACGGT GACAAGTCTC TATCTGGTCT TCCAGATGGG AGTCATATTC 
CCACAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032590.2
CDS	173..3001
Translation	MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFVNLKERCFLTQLAGFLANRQKKYKYEECKDLIRFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLQEGRDASRSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVQKSSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILSVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFLTQLAGFLANRQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHTQERELTQLREKLREGRDASLSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSALIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKIRRGRRSKKKRRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDRCYSTPSMYCELRDSFQHYRSVFYSFEEQHISFALDMDNRFFTLTVTSLYLVFQMGVIFPQ

Target ORF information:

RefSeq Version	NM_001037501.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037501.2

ORF Insert Sequence:

ATGGTGGTAT CAGCCGGCCC TTGGTCCAGC GAGAAGGCAG AGATGAACAT TCTAGAAATC 
AACGAGAAAT TGCGCCCCCA GTTGGCAGAG AACAAACAGC AGTTCGTAAA CCTCAAAGAG 
AGATGTTTTC TAACTCAACT GGCCGGCTTC CTGGCCAACC GACAGAAGAA ATACAAGTAT 
GAAGAGTGTA AAGACCTCAT AAGATTTATG CTGAGGAATG AGCGACAGTT CAAGGAGGAG 
AAGCTTGCAG AGCAGCTCAA GCAAGCTGAG GAGCTCAGGC AATATAAAGT CCTGGTTCAC 
TCTCAGGAAC GAGAGCTGAC GCAGTTAAAG GAGAAGTTAC AGGAAGGGAG AGATGCCTCC 
CGCTCATTGA ATGAGCATCT CCAGGCCCTC CTCACTCTGG ATGAGCCGGA CAAGTCCCAG 
GGGCAGGACC TCCAAGAACA GCTGGCTGAG GGGTGTAGAC TGGCACAGCA CCTTGTCCAA 
AAGCTCAGCC CAGAAAATGA CGAAGATGAG GATGAAGATG TTCAAGTTGA GGAGGATGAG 
AAAGTGCAGA AATCATCTGC CCCCAGGGAG GTGCAGAAGG CTGAAGAGAG CAAAGTCCCT 
GAGGACTCAC TGGAGGAATG TGCCATCACT TGTTCAAATA GCCACGGCCC TTGTGACTCC 
AACCAGCCTC ACAAGAACAT CAAAATCACA TTTGAGGAAG ACGAAGTCAA CTCAACTCTG 
GTTGTAGACA GAGAATCCTC TCATGATGAA TGTCAGGATG CTCTAAACAT TCTCTCAGTC 
CCTGGCCCCA CCTCTTCTGC CACAAACGTC AGCATGGTGG TATCAGCCGG CCCTTTGTCC 
AGCGAGAAGG CAGAGATGAA CATTCTAGAA ATCAATGAGA AATTGCACCC CCAGCTGGCA 
GAGAAGAAAC AGCAGTTCAG AAACCTCAAA GAGAAATGTT TTCTAACTCA ACTGGCCGGC 
TTCCTGGCCA ACCGACAGAA CAAATACAAA TATGAAGAGT GCAAAGATCT CATAAAATCT 
ATGCTGAGGA ATGAGCGACA GTTCAAGGAG GAGAAGCTTG CAGAGCAGCT CAAGCAAGCT 
GAGGAGCTCA GGCAATATAA AGTCCTGGTT CACACTCAGG AACGAGAGCT GACCCAGTTA 
AGGGAGAAGT TGCGGGAAGG GAGAGATGCC TCCCTCTCAT TGAATGAGCA TCTCCAGGCC 
CTCCTCACTC CGGATGAGCC GGACAAGTCC CAGGGGCAGG ACCTCCAAGA ACAGCTGGCT 
GAGGGGTGTA GACTGGCACA GCACCTTGTC CAAAAGCTCA GCCCAGAAAA TGACAACGAT 
GACGATGAAG ATGTTCAAGT TGAGGTGGCT GAGAAAGTGC AGAAATCGTC TGCCCCCAGG 
GAGATGCAGA AGGCTGAAGA AAAGGAAGTC CCTGAGGACT CACTGGAGGA ATGTGCCATC 
ACTTATTCAA ATAGCCATGG CCCTTATGAC TCCAACCAGC CACATAGGAA AACCAAAATC 
ACATTTGAGG AAGACAAAGT CGACTCAGCT CTCATTGGCT CATCCTCTCA TGTTGAATGG 
GAGGATGCTG TACACATTAT TCCAGAAAAT GAAAGTGATG ATGAGGAAGA GGAAGAAAAA 
GGACCAGTGT CTCCCAGGAA TCTGCAGGAG TCTGAAGAGG AGGAAGTCCC CCAGGAGTCC 
TGGGATGAAG GTTATTCGAC TCTCTCAATT CCTCCTGAAA TGTTGGCCTC GTACAAGTCT 
TACAGCAGCA CATTTCACTC ATTAGAGGAA CAGCAAGTCT GCATGGCTGT TGACATAGGC 
AGACATCGGT GGGATCAAGT GAAAAAGGAG GACCAAGAGG CAACAGGTCC CAGGCTCAGC 
AGGGAGCTGC TGGATGAGAA AGGGCCTGAA GTCTTGCAGG ACTCACTGGA TAGATGTTAT 
TCAACTCCTT CAGGTTGCCT TGAACTGACT GACTCATGCC AGCCCTACAG AAGTGCGTTT 
TACATATTGG AGCAACAGCG TGTTGGCTTG GCTGTTGACA TGGATGAAAT TGAAAAGTAC 
CAAGAAGTGG AAGAAGACCA AGACCCATCA TGCCCCAGGC TCAGCAGGGA GCTGCTGGAT 
GAGAAAGAGC CTGAAGTCTT GCAGGACTCA CTGGATAGAT GTTATTCGAC TCCTTCAGGT 
TATCTTGAAC TGCCTGACTT AGGCCAGCCC TACAGCAGTG CTGTTTACTC ATTGGAGGAA 
CAGTACCTTG GCTTGGCTCT TGACGTGGAC AGAATTAAAA AGGACCAAGA AGAGGAAGAA 
GACCAAGGCC CACCATGCCC CAGGCTCAGC AGGGAGCTGC TGGAGGTAGT AGAGCCTGAA 
GTCTTGCAGG ACTCACTGGA TAGATGTTAT TCAACTCCTT CCAGTTGTCT TGAACAGCCT 
GACTCCTGCC AGCCGTATGG AAGTTCCTTT TATGCATTGG AGGAAAAACA TGTTGGCTTT 
TCTCTTGACG TGGGAGAAAT TGAAAAGAAG GGGAAGGGGA AGATAAGAAG GGGAAGAAGA 
TCAAAGAAGA AAAGAAGAAG GGGAAGAAAA GAAGGGGAAG AAGATCAAAA CCCACCATGC 
CCCAGGCTCA ACAGCGTGCT GATGGAAGTG GAAGAGCCTG AAGTCTTACA GGACTCACTG 
GATAGATGTT ATTCGACTCC ATCAATGTAC TGTGAACTAC GTGACTCATT CCAGCACTAC 
AGAAGTGTGT TTTACTCATT TGAGGAACAG CACATCAGCT TTGCCCTTGA CATGGACAAT 
AGGTTCTTTA CTTTGACGGT GACAAGTCTC TATCTGGTCT TCCAGATGGG AGTCATATTC 
CCACAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NBPF8 ( NM_001037501.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032590.2 Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14447
Clone ID Related Accession (Same CDS sequence)	NM_001037501.2 , NM_001037501.3
Accession Version	NM_001037501.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2829bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	putative neuroblastoma breakpoint family member 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC241952.2. On May 19, 2017 this sequence version replaced NM_001037501.2. Transcript Variant: This variant (1) represents the longest transcript. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.108304.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA2142853 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGGTAT CAGCCGGCCC TTGGTCCAGC GAGAAGGCAG AGATGAACAT TCTAGAAATC 
AACGAGAAAT TGCGCCCCCA GTTGGCAGAG AACAAACAGC AGTTCGTAAA CCTCAAAGAG 
AGATGTTTTC TAACTCAACT GGCCGGCTTC CTGGCCAACC GACAGAAGAA ATACAAGTAT 
GAAGAGTGTA AAGACCTCAT AAGATTTATG CTGAGGAATG AGCGACAGTT CAAGGAGGAG 
AAGCTTGCAG AGCAGCTCAA GCAAGCTGAG GAGCTCAGGC AATATAAAGT CCTGGTTCAC 
TCTCAGGAAC GAGAGCTGAC GCAGTTAAAG GAGAAGTTAC AGGAAGGGAG AGATGCCTCC 
CGCTCATTGA ATGAGCATCT CCAGGCCCTC CTCACTCTGG ATGAGCCGGA CAAGTCCCAG 
GGGCAGGACC TCCAAGAACA GCTGGCTGAG GGGTGTAGAC TGGCACAGCA CCTTGTCCAA 
AAGCTCAGCC CAGAAAATGA CGAAGATGAG GATGAAGATG TTCAAGTTGA GGAGGATGAG 
AAAGTGCAGA AATCATCTGC CCCCAGGGAG GTGCAGAAGG CTGAAGAGAG CAAAGTCCCT 
GAGGACTCAC TGGAGGAATG TGCCATCACT TGTTCAAATA GCCACGGCCC TTGTGACTCC 
AACCAGCCTC ACAAGAACAT CAAAATCACA TTTGAGGAAG ACGAAGTCAA CTCAACTCTG 
GTTGTAGACA GAGAATCCTC TCATGATGAA TGTCAGGATG CTCTAAACAT TCTCTCAGTC 
CCTGGCCCCA CCTCTTCTGC CACAAACGTC AGCATGGTGG TATCAGCCGG CCCTTTGTCC 
AGCGAGAAGG CAGAGATGAA CATTCTAGAA ATCAATGAGA AATTGCACCC CCAGCTGGCA 
GAGAAGAAAC AGCAGTTCAG AAACCTCAAA GAGAAATGTT TTCTAACTCA ACTGGCCGGC 
TTCCTGGCCA ACCGACAGAA CAAATACAAA TATGAAGAGT GCAAAGATCT CATAAAATCT 
ATGCTGAGGA ATGAGCGACA GTTCAAGGAG GAGAAGCTTG CAGAGCAGCT CAAGCAAGCT 
GAGGAGCTCA GGCAATATAA AGTCCTGGTT CACACTCAGG AACGAGAGCT GACCCAGTTA 
AGGGAGAAGT TGCGGGAAGG GAGAGATGCC TCCCTCTCAT TGAATGAGCA TCTCCAGGCC 
CTCCTCACTC CGGATGAGCC GGACAAGTCC CAGGGGCAGG ACCTCCAAGA ACAGCTGGCT 
GAGGGGTGTA GACTGGCACA GCACCTTGTC CAAAAGCTCA GCCCAGAAAA TGACAACGAT 
GACGATGAAG ATGTTCAAGT TGAGGTGGCT GAGAAAGTGC AGAAATCGTC TGCCCCCAGG 
GAGATGCAGA AGGCTGAAGA AAAGGAAGTC CCTGAGGACT CACTGGAGGA ATGTGCCATC 
ACTTATTCAA ATAGCCATGG CCCTTATGAC TCCAACCAGC CACATAGGAA AACCAAAATC 
ACATTTGAGG AAGACAAAGT CGACTCAGCT CTCATTGGCT CATCCTCTCA TGTTGAATGG 
GAGGATGCTG TACACATTAT TCCAGAAAAT GAAAGTGATG ATGAGGAAGA GGAAGAAAAA 
GGACCAGTGT CTCCCAGGAA TCTGCAGGAG TCTGAAGAGG AGGAAGTCCC CCAGGAGTCC 
TGGGATGAAG GTTATTCGAC TCTCTCAATT CCTCCTGAAA TGTTGGCCTC GTACAAGTCT 
TACAGCAGCA CATTTCACTC ATTAGAGGAA CAGCAAGTCT GCATGGCTGT TGACATAGGC 
AGACATCGGT GGGATCAAGT GAAAAAGGAG GACCAAGAGG CAACAGGTCC CAGGCTCAGC 
AGGGAGCTGC TGGATGAGAA AGGGCCTGAA GTCTTGCAGG ACTCACTGGA TAGATGTTAT 
TCAACTCCTT CAGGTTGCCT TGAACTGACT GACTCATGCC AGCCCTACAG AAGTGCGTTT 
TACATATTGG AGCAACAGCG TGTTGGCTTG GCTGTTGACA TGGATGAAAT TGAAAAGTAC 
CAAGAAGTGG AAGAAGACCA AGACCCATCA TGCCCCAGGC TCAGCAGGGA GCTGCTGGAT 
GAGAAAGAGC CTGAAGTCTT GCAGGACTCA CTGGATAGAT GTTATTCGAC TCCTTCAGGT 
TATCTTGAAC TGCCTGACTT AGGCCAGCCC TACAGCAGTG CTGTTTACTC ATTGGAGGAA 
CAGTACCTTG GCTTGGCTCT TGACGTGGAC AGAATTAAAA AGGACCAAGA AGAGGAAGAA 
GACCAAGGCC CACCATGCCC CAGGCTCAGC AGGGAGCTGC TGGAGGTAGT AGAGCCTGAA 
GTCTTGCAGG ACTCACTGGA TAGATGTTAT TCAACTCCTT CCAGTTGTCT TGAACAGCCT 
GACTCCTGCC AGCCGTATGG AAGTTCCTTT TATGCATTGG AGGAAAAACA TGTTGGCTTT 
TCTCTTGACG TGGGAGAAAT TGAAAAGAAG GGGAAGGGGA AGATAAGAAG GGGAAGAAGA 
TCAAAGAAGA AAAGAAGAAG GGGAAGAAAA GAAGGGGAAG AAGATCAAAA CCCACCATGC 
CCCAGGCTCA ACAGCGTGCT GATGGAAGTG GAAGAGCCTG AAGTCTTACA GGACTCACTG 
GATAGATGTT ATTCGACTCC ATCAATGTAC TGTGAACTAC GTGACTCATT CCAGCACTAC 
AGAAGTGTGT TTTACTCATT TGAGGAACAG CACATCAGCT TTGCCCTTGA CATGGACAAT 
AGGTTCTTTA CTTTGACGGT GACAAGTCTC TATCTGGTCT TCCAGATGGG AGTCATATTC 
CCACAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032590.2
CDS	981..3809
Translation	MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFVNLKERCFLTQLAGFLANRQKKYKYEECKDLIRFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLQEGRDASRSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVQKSSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILSVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFLTQLAGFLANRQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHTQERELTQLREKLREGRDASLSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSALIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKIRRGRRSKKKRRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDRCYSTPSMYCELRDSFQHYRSVFYSFEEQHISFALDMDNRFFTLTVTSLYLVFQMGVIFPQ

Target ORF information:

RefSeq Version	NM_001037501.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NBPF member 8 (NBPF8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037501.3

ORF Insert Sequence:

ATGGTGGTAT CAGCCGGCCC TTGGTCCAGC GAGAAGGCAG AGATGAACAT TCTAGAAATC 
AACGAGAAAT TGCGCCCCCA GTTGGCAGAG AACAAACAGC AGTTCGTAAA CCTCAAAGAG 
AGATGTTTTC TAACTCAACT GGCCGGCTTC CTGGCCAACC GACAGAAGAA ATACAAGTAT 
GAAGAGTGTA AAGACCTCAT AAGATTTATG CTGAGGAATG AGCGACAGTT CAAGGAGGAG 
AAGCTTGCAG AGCAGCTCAA GCAAGCTGAG GAGCTCAGGC AATATAAAGT CCTGGTTCAC 
TCTCAGGAAC GAGAGCTGAC GCAGTTAAAG GAGAAGTTAC AGGAAGGGAG AGATGCCTCC 
CGCTCATTGA ATGAGCATCT CCAGGCCCTC CTCACTCTGG ATGAGCCGGA CAAGTCCCAG 
GGGCAGGACC TCCAAGAACA GCTGGCTGAG GGGTGTAGAC TGGCACAGCA CCTTGTCCAA 
AAGCTCAGCC CAGAAAATGA CGAAGATGAG GATGAAGATG TTCAAGTTGA GGAGGATGAG 
AAAGTGCAGA AATCATCTGC CCCCAGGGAG GTGCAGAAGG CTGAAGAGAG CAAAGTCCCT 
GAGGACTCAC TGGAGGAATG TGCCATCACT TGTTCAAATA GCCACGGCCC TTGTGACTCC 
AACCAGCCTC ACAAGAACAT CAAAATCACA TTTGAGGAAG ACGAAGTCAA CTCAACTCTG 
GTTGTAGACA GAGAATCCTC TCATGATGAA TGTCAGGATG CTCTAAACAT TCTCTCAGTC 
CCTGGCCCCA CCTCTTCTGC CACAAACGTC AGCATGGTGG TATCAGCCGG CCCTTTGTCC 
AGCGAGAAGG CAGAGATGAA CATTCTAGAA ATCAATGAGA AATTGCACCC CCAGCTGGCA 
GAGAAGAAAC AGCAGTTCAG AAACCTCAAA GAGAAATGTT TTCTAACTCA ACTGGCCGGC 
TTCCTGGCCA ACCGACAGAA CAAATACAAA TATGAAGAGT GCAAAGATCT CATAAAATCT 
ATGCTGAGGA ATGAGCGACA GTTCAAGGAG GAGAAGCTTG CAGAGCAGCT CAAGCAAGCT 
GAGGAGCTCA GGCAATATAA AGTCCTGGTT CACACTCAGG AACGAGAGCT GACCCAGTTA 
AGGGAGAAGT TGCGGGAAGG GAGAGATGCC TCCCTCTCAT TGAATGAGCA TCTCCAGGCC 
CTCCTCACTC CGGATGAGCC GGACAAGTCC CAGGGGCAGG ACCTCCAAGA ACAGCTGGCT 
GAGGGGTGTA GACTGGCACA GCACCTTGTC CAAAAGCTCA GCCCAGAAAA TGACAACGAT 
GACGATGAAG ATGTTCAAGT TGAGGTGGCT GAGAAAGTGC AGAAATCGTC TGCCCCCAGG 
GAGATGCAGA AGGCTGAAGA AAAGGAAGTC CCTGAGGACT CACTGGAGGA ATGTGCCATC 
ACTTATTCAA ATAGCCATGG CCCTTATGAC TCCAACCAGC CACATAGGAA AACCAAAATC 
ACATTTGAGG AAGACAAAGT CGACTCAGCT CTCATTGGCT CATCCTCTCA TGTTGAATGG 
GAGGATGCTG TACACATTAT TCCAGAAAAT GAAAGTGATG ATGAGGAAGA GGAAGAAAAA 
GGACCAGTGT CTCCCAGGAA TCTGCAGGAG TCTGAAGAGG AGGAAGTCCC CCAGGAGTCC 
TGGGATGAAG GTTATTCGAC TCTCTCAATT CCTCCTGAAA TGTTGGCCTC GTACAAGTCT 
TACAGCAGCA CATTTCACTC ATTAGAGGAA CAGCAAGTCT GCATGGCTGT TGACATAGGC 
AGACATCGGT GGGATCAAGT GAAAAAGGAG GACCAAGAGG CAACAGGTCC CAGGCTCAGC 
AGGGAGCTGC TGGATGAGAA AGGGCCTGAA GTCTTGCAGG ACTCACTGGA TAGATGTTAT 
TCAACTCCTT CAGGTTGCCT TGAACTGACT GACTCATGCC AGCCCTACAG AAGTGCGTTT 
TACATATTGG AGCAACAGCG TGTTGGCTTG GCTGTTGACA TGGATGAAAT TGAAAAGTAC 
CAAGAAGTGG AAGAAGACCA AGACCCATCA TGCCCCAGGC TCAGCAGGGA GCTGCTGGAT 
GAGAAAGAGC CTGAAGTCTT GCAGGACTCA CTGGATAGAT GTTATTCGAC TCCTTCAGGT 
TATCTTGAAC TGCCTGACTT AGGCCAGCCC TACAGCAGTG CTGTTTACTC ATTGGAGGAA 
CAGTACCTTG GCTTGGCTCT TGACGTGGAC AGAATTAAAA AGGACCAAGA AGAGGAAGAA 
GACCAAGGCC CACCATGCCC CAGGCTCAGC AGGGAGCTGC TGGAGGTAGT AGAGCCTGAA 
GTCTTGCAGG ACTCACTGGA TAGATGTTAT TCAACTCCTT CCAGTTGTCT TGAACAGCCT 
GACTCCTGCC AGCCGTATGG AAGTTCCTTT TATGCATTGG AGGAAAAACA TGTTGGCTTT 
TCTCTTGACG TGGGAGAAAT TGAAAAGAAG GGGAAGGGGA AGATAAGAAG GGGAAGAAGA 
TCAAAGAAGA AAAGAAGAAG GGGAAGAAAA GAAGGGGAAG AAGATCAAAA CCCACCATGC 
CCCAGGCTCA ACAGCGTGCT GATGGAAGTG GAAGAGCCTG AAGTCTTACA GGACTCACTG 
GATAGATGTT ATTCGACTCC ATCAATGTAC TGTGAACTAC GTGACTCATT CCAGCACTAC 
AGAAGTGTGT TTTACTCATT TGAGGAACAG CACATCAGCT TTGCCCTTGA CATGGACAAT 
AGGTTCTTTA CTTTGACGGT GACAAGTCTC TATCTGGTCT TCCAGATGGG AGTCATATTC 
CCACAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DUF1220-domain copy number implicated in human brain-size pathology and evolution.
American journal of human genetics91(3)444-54(2012 Sep)
Dumas LJ,O'Bleness MS,Davis JM,Dickens CM,Anderson N,Keeney JG,Jackson J,Sikela M,Raznahan A,Giedd J,Rapoport J,Nagamani SS,Erez A,Brunetti-Pierri N,Sugalski R,Lupski JR,Fingerlin T,Cheung SW,Sikela JM

Evolutionary history and genome organization of DUF1220 protein domains.
G3 (Bethesda, Md.)2(9)977-86(2012 Sep)
O'Bleness MS,Dickens CM,Dumas LJ,Kehrer-Sawatzki H,Wyckoff GJ,Sikela JM

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.
Molecular biology and evolution22(11)2265-74(2005 Nov)
Vandepoele K,Van Roy N,Staes K,Speleman F,van Roy F

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NBPF8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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