TSPYL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TSPYL1
Entrez Gene ID	7259
Full Name	TSPY like 1
Synonyms	TSPYL
General protein information	Preferred Names TSPY like 1 Names testis-specific Y-encoded-like protein 1 TSPY-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q22.1
Summary	The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009].
Disorder MIM:	604714
Disorder Html:	Sudden infant death with dysgenesis of the testes syndrome, 608800 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003309.3	NP_003300.1	testis-specific Y-encoded-like protein 1
NM_003309.4	NP_003300.1	testis-specific Y-encoded-like protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TSPYL1	NP_003300.1
	TSPYL1	XP_001111828.1
Pan troglodytes (chimpanzee)	TSPYL1	XP_003950956.1
Bos taurus (cattle)	TSPYL1	NP_001069579.1
Mus musculus (house mouse)	Tspyl1	NP_033459.1
Canis lupus familiaris (dog)	TSPYL1	XP_005627848.1
Bos taurus (cattle)	LOC100336701	XP_005207262.1
Bos taurus (cattle)	LOC100336013	XP_005207279.1
Rattus norvegicus (Norway rat)	Tspyl1	NP_001013051.1

Gene Ontology
Bibliography

Related articles in PubMed

Spermatogenic phenotype of testis-specific protein, Y-encoded, 1 (TSPY1) dosage deficiency is independent of variations in TSPY-like 1 (TSPYL1) and TSPY-like 5 (TSPYL5): a case-control study in a Han Chinese population.
Yang X, Leng X, Tu W, Liu Y, Xu J, Pei X, Ma Y, Yang D, Yang Y
Reproduction, fertility, and development(2017 Aug)

Variants in TSPYL1 are not associated with sudden infant death syndrome in a cohort of deceased infants from Switzerland.
Schubert S, Haas C, Bartsch C, Mirshekarnejad M, Kohrs S, Roettinger I, Grosshennig A, Stuhrmann M, Scholz C, Schmidtke J
Molecular and cellular probes29(1)31-4(2015 Feb)

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
Armour SM, Bennett EJ, Braun CR, Zhang XY, McMahon SB, Gygi SP, Harper JW, Sinclair DA
Molecular and cellular biology33(8)1487-502(2013 Apr)

Should TSPYL1 mutation screening be included in routine diagnostics of male idiopathic infertility?
Javaher P, Stuhrmann M, Wilke C, Frenzel E, Manukjan G, Grosshenig A, Dechend F, Schwaab E, Schmidtke J, Schubert S
Fertility and sterility97(2)402-6(2012 Feb)

Mutations in the TSPYL1 gene associated with 46,XY disorder of sex development and male infertility.
Vinci G, Brauner R, Tar A, Rouba H, Sheth J, Sheth F, Ravel C, McElreavey K, Bashamboo A
Fertility and sterility92(4)1347-50(2009 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that mutations and polymorphisms in the TSPYL1 gene were not associated with sudden infant death syndrome in a cohort of 165 deceased Swiss infants.
Title: Variants in TSPYL1 are not associated with sudden infant death syndrome in a cohort of deceased infants from Switzerland.

Mutations in the TSPYL1 gene do not seem to play a major role in the pathogenesis of idiopathic male infertility, and mutation screening of the TSPYL1 gene can currently not be recommended in routine diagnostics of idiopathic male infertility.
Title: Should TSPYL1 mutation screening be included in routine diagnostics of male idiopathic infertility?

Mutations in TSPYL1 may contribute to anomalies of testicular development/function.
Title: Mutations in the TSPYL1 gene associated with 46,XY disorder of sex development and male infertility.

The chromatin remodeling factor TSPYL1 had a very similar pattern of expression with an incremental increase in HPFH and decreased expression in deltabeta-thalassemia.
Title: Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic investigation of the TSPYL1 gene in sudden infant death syndrome.

The following TSPYL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TSPYL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23114	NM_003309.4 Latest version!	Homo sapiens TSPY like 1 (TSPYL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu23114	NM_003309.3	Homo sapiens TSPY like 1 (TSPYL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TSPYL1 ( NM_003309.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003300.1 Homo sapiens TSPY like 1 (TSPYL1), mRNA.

Price & Availability↑

CloneID	OHu23114
Clone ID Related Accession (Same CDS sequence)	NM_003309.3 , NM_003309.4
Accession Version	NM_003309.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	testis-specific Y-encoded-like protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL050331.11. This sequence is a reference standard in the RefSeqGene project. On Dec 3, 2009 this sequence version replaced NM_003309.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGGCC TGGATGGGGT CAAGAGGACC ACTCCCCTCC AAACCCACAG CATCATTATT 
TCTGACCAAG TCCCGAGCGA CCAGGACGCA CACCAGTACC TGAGGCTCCG CGACCAAAGC 
GAGGCGACAC AGGTGATGGC GGAGCCGGGT GAGGGAGGCT CGGAGACCGT CGCGCTCCCG 
CCTCCACCGC CTTCAGAGGA GGGGGGCGTA CCCCAGGATG CCGCGGGCCG TGGCGGTACT 
CCCCAGATCC GAGTTGTTGG GGGTCGCGGT CATGTGGCGA TCAAAGCCGG GCAGGAAGAG 
GGCCAGCCTC CCGCCGAAGG CCTGGCAGCC GCTTCTGTGG TGATGGCAGC CGACCGCAGC 
CTGAAAAAGG GCGTTCAGGG TGGAGAGAAG GCCCTAGAAA TCTGTGGCGC CCAGAGATCC 
GCGTCTGAGC TGACGGCGGG GGCGGAGGCT GAGGCGGAGG AGGTGAAGAC AGGAAAGTGC 
GCCACCGTCT CAGCAGCCGT GGCTGAGAGG GAGAGCGCTG AGGTGGTGAA GGAAGGCCTG 
GCGGAGAAGG AGGTAATGGA GGAGCAGATG GAGGTAGAGG AGCAGCCGCC AGAAGGTGAA 
GAAATAGAAG TGGCGGAGGA GGATAGATTG GAGGAGGAGG CGAGGGAGGA AGAAGGGCCC 
TGGCCTTTGC ATGAGGCTCT CCGCATGGAC CCTCTGGAGG CCATCCAGCT GGAACTGGAC 
ACTGTGAATG CTCAGGCCGA CAGGGCCTTC CAACAGCTGG AGCACAAGTT TGGGCGGATG 
CGTCGACACT ACCTGGAGCG GAGGAACTAC ATCATTCAGA ATATCCCGGG CTTCTGGATG 
ACTGCTTTTC GAAACCACCC CCAGTTGTCC GCCATGATTA GGGGCCAAGA TGCAGAGATG 
TTAAGGTACA TAACCAATTT AGAGGTGAAG GAACTCAGAC ACCCTAGAAC CGGTTGCAAG 
TTCAAGTTCT TCTTTAGAAG AAACCCCTAC TTCAGAAACA AGCTGATTGT CAAGGAATAT 
GAGGTAAGAT CCTCCGGCCG AGTGGTGTCT CTTTCTACTC CAATTATATG GCGCAGGGGG 
CATGAACCCC AGTCCTTCAT TCGCAGAAAC CAAGACCTCA TCTGCAGCTT CTTCACTTGG 
TTTTCAGACC ACAGCCTTCC AGAGTCCGAC AAAATTGCTG AGATTATTAA AGAGGATCTG 
TGGCCAAATC CACTGCAATA CTACCTGTTG CGTGAAGGAG TCCGTAGAGC CCGACGTCGC 
CCGCTAAGGG AGCCTGTAGA GATCCCCAGG CCCTTTGGGT TCCAGTCTGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003300.1
CDS	288..1601
Translation	MSGLDGVKRTTPLQTHSIIISDQVPSDQDAHQYLRLRDQSEATQVMAEPGEGGSETVALPPPPPSEEGGVPQDAAGRGGTPQIRVVGGRGHVAIKAGQEEGQPPAEGLAAASVVMAADRSLKKGVQGGEKALEICGAQRSASELTAGAEAEAEEVKTGKCATVSAAVAERESAEVVKEGLAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRMDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYLLREGVRRARRRPLREPVEIPRPFGFQSG

Target ORF information:

RefSeq Version	NM_003309.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TSPY like 1 (TSPYL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003309.3

ORF Insert Sequence:

ATGAGCGGCC TGGATGGGGT CAAGAGGACC ACTCCCCTCC AAACCCACAG CATCATTATT 
TCTGACCAAG TCCCGAGCGA CCAGGACGCA CACCAGTACC TGAGGCTCCG CGACCAAAGC 
GAGGCGACAC AGGTGATGGC GGAGCCGGGT GAGGGAGGCT CGGAGACCGT CGCGCTCCCG 
CCTCCACCGC CTTCAGAGGA GGGGGGCGTA CCCCAGGATG CCGCGGGCCG TGGCGGTACT 
CCCCAGATCC GAGTTGTTGG GGGTCGCGGT CATGTGGCGA TCAAAGCCGG GCAGGAAGAG 
GGCCAGCCTC CCGCCGAAGG CCTGGCAGCC GCTTCTGTGG TGATGGCAGC CGACCGCAGC 
CTGAAAAAGG GCGTTCAGGG TGGAGAGAAG GCCCTAGAAA TCTGTGGCGC CCAGAGATCC 
GCGTCTGAGC TGACGGCGGG GGCGGAGGCT GAGGCGGAGG AGGTGAAGAC AGGAAAGTGC 
GCCACCGTCT CAGCAGCCGT GGCTGAGAGG GAGAGCGCTG AGGTGGTGAA GGAAGGCCTG 
GCGGAGAAGG AGGTAATGGA GGAGCAGATG GAGGTAGAGG AGCAGCCGCC AGAAGGTGAA 
GAAATAGAAG TGGCGGAGGA GGATAGATTG GAGGAGGAGG CGAGGGAGGA AGAAGGGCCC 
TGGCCTTTGC ATGAGGCTCT CCGCATGGAC CCTCTGGAGG CCATCCAGCT GGAACTGGAC 
ACTGTGAATG CTCAGGCCGA CAGGGCCTTC CAACAGCTGG AGCACAAGTT TGGGCGGATG 
CGTCGACACT ACCTGGAGCG GAGGAACTAC ATCATTCAGA ATATCCCGGG CTTCTGGATG 
ACTGCTTTTC GAAACCACCC CCAGTTGTCC GCCATGATTA GGGGCCAAGA TGCAGAGATG 
TTAAGGTACA TAACCAATTT AGAGGTGAAG GAACTCAGAC ACCCTAGAAC CGGTTGCAAG 
TTCAAGTTCT TCTTTAGAAG AAACCCCTAC TTCAGAAACA AGCTGATTGT CAAGGAATAT 
GAGGTAAGAT CCTCCGGCCG AGTGGTGTCT CTTTCTACTC CAATTATATG GCGCAGGGGG 
CATGAACCCC AGTCCTTCAT TCGCAGAAAC CAAGACCTCA TCTGCAGCTT CTTCACTTGG 
TTTTCAGACC ACAGCCTTCC AGAGTCCGAC AAAATTGCTG AGATTATTAA AGAGGATCTG 
TGGCCAAATC CACTGCAATA CTACCTGTTG CGTGAAGGAG TCCGTAGAGC CCGACGTCGC 
CCGCTAAGGG AGCCTGTAGA GATCCCCAGG CCCTTTGGGT TCCAGTCTGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TSPYL1 ( NM_003309.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003300.1 Homo sapiens TSPY like 1 (TSPYL1), mRNA.

Price & Availability↑

CloneID	OHu23114
Clone ID Related Accession (Same CDS sequence)	NM_003309.3 , NM_003309.4
Accession Version	NM_003309.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	testis-specific Y-encoded-like protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL050331.11. On Sep 27, 2019 this sequence version replaced NM_003309.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC048969.1, AL136629.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGGCC TGGATGGGGT CAAGAGGACC ACTCCCCTCC AAACCCACAG CATCATTATT 
TCTGACCAAG TCCCGAGCGA CCAGGACGCA CACCAGTACC TGAGGCTCCG CGACCAAAGC 
GAGGCGACAC AGGTGATGGC GGAGCCGGGT GAGGGAGGCT CGGAGACCGT CGCGCTCCCG 
CCTCCACCGC CTTCAGAGGA GGGGGGCGTA CCCCAGGATG CCGCGGGCCG TGGCGGTACT 
CCCCAGATCC GAGTTGTTGG GGGTCGCGGT CATGTGGCGA TCAAAGCCGG GCAGGAAGAG 
GGCCAGCCTC CCGCCGAAGG CCTGGCAGCC GCTTCTGTGG TGATGGCAGC CGACCGCAGC 
CTGAAAAAGG GCGTTCAGGG TGGAGAGAAG GCCCTAGAAA TCTGTGGCGC CCAGAGATCC 
GCGTCTGAGC TGACGGCGGG GGCGGAGGCT GAGGCGGAGG AGGTGAAGAC AGGAAAGTGC 
GCCACCGTCT CAGCAGCCGT GGCTGAGAGG GAGAGCGCTG AGGTGGTGAA GGAAGGCCTG 
GCGGAGAAGG AGGTAATGGA GGAGCAGATG GAGGTAGAGG AGCAGCCGCC AGAAGGTGAA 
GAAATAGAAG TGGCGGAGGA GGATAGATTG GAGGAGGAGG CGAGGGAGGA AGAAGGGCCC 
TGGCCTTTGC ATGAGGCTCT CCGCATGGAC CCTCTGGAGG CCATCCAGCT GGAACTGGAC 
ACTGTGAATG CTCAGGCCGA CAGGGCCTTC CAACAGCTGG AGCACAAGTT TGGGCGGATG 
CGTCGACACT ACCTGGAGCG GAGGAACTAC ATCATTCAGA ATATCCCGGG CTTCTGGATG 
ACTGCTTTTC GAAACCACCC CCAGTTGTCC GCCATGATTA GGGGCCAAGA TGCAGAGATG 
TTAAGGTACA TAACCAATTT AGAGGTGAAG GAACTCAGAC ACCCTAGAAC CGGTTGCAAG 
TTCAAGTTCT TCTTTAGAAG AAACCCCTAC TTCAGAAACA AGCTGATTGT CAAGGAATAT 
GAGGTAAGAT CCTCCGGCCG AGTGGTGTCT CTTTCTACTC CAATTATATG GCGCAGGGGG 
CATGAACCCC AGTCCTTCAT TCGCAGAAAC CAAGACCTCA TCTGCAGCTT CTTCACTTGG 
TTTTCAGACC ACAGCCTTCC AGAGTCCGAC AAAATTGCTG AGATTATTAA AGAGGATCTG 
TGGCCAAATC CACTGCAATA CTACCTGTTG CGTGAAGGAG TCCGTAGAGC CCGACGTCGC 
CCGCTAAGGG AGCCTGTAGA GATCCCCAGG CCCTTTGGGT TCCAGTCTGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003300.1
CDS	101..1414
Translation	MSGLDGVKRTTPLQTHSIIISDQVPSDQDAHQYLRLRDQSEATQVMAEPGEGGSETVALPPPPPSEEGGVPQDAAGRGGTPQIRVVGGRGHVAIKAGQEEGQPPAEGLAAASVVMAADRSLKKGVQGGEKALEICGAQRSASELTAGAEAEAEEVKTGKCATVSAAVAERESAEVVKEGLAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRMDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTPIIWRRGHEPQSFIRRNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYLLREGVRRARRRPLREPVEIPRPFGFQSG

Target ORF information:

RefSeq Version	NM_003309.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TSPY like 1 (TSPYL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003309.4

ORF Insert Sequence:

ATGAGCGGCC TGGATGGGGT CAAGAGGACC ACTCCCCTCC AAACCCACAG CATCATTATT 
TCTGACCAAG TCCCGAGCGA CCAGGACGCA CACCAGTACC TGAGGCTCCG CGACCAAAGC 
GAGGCGACAC AGGTGATGGC GGAGCCGGGT GAGGGAGGCT CGGAGACCGT CGCGCTCCCG 
CCTCCACCGC CTTCAGAGGA GGGGGGCGTA CCCCAGGATG CCGCGGGCCG TGGCGGTACT 
CCCCAGATCC GAGTTGTTGG GGGTCGCGGT CATGTGGCGA TCAAAGCCGG GCAGGAAGAG 
GGCCAGCCTC CCGCCGAAGG CCTGGCAGCC GCTTCTGTGG TGATGGCAGC CGACCGCAGC 
CTGAAAAAGG GCGTTCAGGG TGGAGAGAAG GCCCTAGAAA TCTGTGGCGC CCAGAGATCC 
GCGTCTGAGC TGACGGCGGG GGCGGAGGCT GAGGCGGAGG AGGTGAAGAC AGGAAAGTGC 
GCCACCGTCT CAGCAGCCGT GGCTGAGAGG GAGAGCGCTG AGGTGGTGAA GGAAGGCCTG 
GCGGAGAAGG AGGTAATGGA GGAGCAGATG GAGGTAGAGG AGCAGCCGCC AGAAGGTGAA 
GAAATAGAAG TGGCGGAGGA GGATAGATTG GAGGAGGAGG CGAGGGAGGA AGAAGGGCCC 
TGGCCTTTGC ATGAGGCTCT CCGCATGGAC CCTCTGGAGG CCATCCAGCT GGAACTGGAC 
ACTGTGAATG CTCAGGCCGA CAGGGCCTTC CAACAGCTGG AGCACAAGTT TGGGCGGATG 
CGTCGACACT ACCTGGAGCG GAGGAACTAC ATCATTCAGA ATATCCCGGG CTTCTGGATG 
ACTGCTTTTC GAAACCACCC CCAGTTGTCC GCCATGATTA GGGGCCAAGA TGCAGAGATG 
TTAAGGTACA TAACCAATTT AGAGGTGAAG GAACTCAGAC ACCCTAGAAC CGGTTGCAAG 
TTCAAGTTCT TCTTTAGAAG AAACCCCTAC TTCAGAAACA AGCTGATTGT CAAGGAATAT 
GAGGTAAGAT CCTCCGGCCG AGTGGTGTCT CTTTCTACTC CAATTATATG GCGCAGGGGG 
CATGAACCCC AGTCCTTCAT TCGCAGAAAC CAAGACCTCA TCTGCAGCTT CTTCACTTGG 
TTTTCAGACC ACAGCCTTCC AGAGTCCGAC AAAATTGCTG AGATTATTAA AGAGGATCTG 
TGGCCAAATC CACTGCAATA CTACCTGTTG CGTGAAGGAG TCCGTAGAGC CCGACGTCGC 
CCGCTAAGGG AGCCTGTAGA GATCCCCAGG CCCTTTGGGT TCCAGTCTGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Spermatogenic phenotype of testis-specific protein, Y-encoded, 1 (TSPY1) dosage deficiency is independent of variations in TSPY-like 1 (TSPYL1) and TSPY-like 5 (TSPYL5): a case-control study in a Han Chinese population.
Reproduction, fertility, and development(2017 Aug)
Yang X,Leng X,Tu W,Liu Y,Xu J,Pei X,Ma Y,Yang D,Yang Y

Variants in TSPYL1 are not associated with sudden infant death syndrome in a cohort of deceased infants from Switzerland.
Molecular and cellular probes29(1)31-4(2015 Feb)
Schubert S,Haas C,Bartsch C,Mirshekarnejad M,Kohrs S,Roettinger I,Grosshennig A,Stuhrmann M,Scholz C,Schmidtke J

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
Molecular and cellular biology33(8)1487-502(2013 Apr)
Armour SM,Bennett EJ,Braun CR,Zhang XY,McMahon SB,Gygi SP,Harper JW,Sinclair DA

Should TSPYL1 mutation screening be included in routine diagnostics of male idiopathic infertility?
Fertility and sterility97(2)402-6(2012 Feb)
Javaher P,Stuhrmann M,Wilke C,Frenzel E,Manukjan G,Grosshenig A,Dechend F,Schwaab E,Schmidtke J,Schubert S

Mutations in the TSPYL1 gene associated with 46,XY disorder of sex development and male infertility.
Fertility and sterility92(4)1347-50(2009 Oct)
Vinci G,Brauner R,Tar A,Rouba H,Sheth J,Sheth F,Ravel C,McElreavey K,Bashamboo A

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TSPYL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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