TSN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TSN
Entrez Gene ID	7247
Full Name	translin
Synonyms	BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN
General protein information	Preferred Names translin Names translin component 3 of promoter of RISC recombination hotspot associated factor recombination hotspot-binding protein testis brain-RNA binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q14.3
Summary	This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012].
Disorder MIM:	600575

mRNA and Protein(s)

mRNA	Protein	Name
NM_004622.3	NP_004613.1	translin isoform 1
NM_001261401.1	NP_001248330.1	translin isoform 2
NM_004622.2	NP_004613.1	translin isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TSN	NP_004613.1
	TSN	XP_001085908.1
Bos taurus (cattle)	TSN	NP_001068890.1
Gallus gallus (chicken)	TSN	NP_990404.1
Neurospora crassa	NCU06664	XP_960911.1
Pan troglodytes (chimpanzee)	TSN	XP_515770.1
Mus musculus (house mouse)	Tsn	NP_035780.1
Arabidopsis thaliana (thale cress)	AT2G37020	NP_565857.2
Danio rerio (zebrafish)	tsn	NP_001020623.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005538	XP_315537.4
Magnaporthe oryzae (rice blast fungus)	MGG_05995	XP_003711841.1
Xenopus tropicalis (tropical clawed frog)	mllt4	NP_001007517.1
Canis lupus familiaris (dog)	TSN	XP_003639748.1
Rattus norvegicus (Norway rat)	Tsn	NP_068530.1
Schizosaccharomyces pombe (fission yeast)	tsn1	NP_594557.2
Oryza sativa (rice)	Os10g0443200	NP_001064703.1
Drosophila melanogaster (fruit fly)	trsn	NP_610591.1

Gene Ontology
Bibliography

Related articles in PubMed

UPF1 helicase promotes TSN-mediated miRNA decay.
Elbarbary RA, Miyoshi K, Hedaya O, Myers JR, Maquat LE
Genes & development31(14)1483-1493(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Gomez-Escobar N, Almobadel N, Alzahrani O, Feichtinger J, Planells-Palop V, Alshehri Z, Thallinger GG, Wakeman JA, McFarlane RJ
Oncotarget7(23)33809-20(2016 Jun)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

Rescuing dicer defects via inhibition of an anti-dicing nuclease.
Asada K, Canestrari E, Fu X, Li Z, Makowski E, Wu YC, Mito JK, Kirsch DG, Baraban J, Paroo Z
Cell reports9(4)1471-81(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results indicate that UPF1 can dissociate miRNAs from their mRNA targets, making the miRNAs susceptible to Tudor-staphylococcal/micrococcal-like nuclease (TSN)-mediated miRNA decay.
Title: UPF1 helicase promotes TSN-mediated miRNA decay.

Translin and Trax control telomere-associated transcript levels in human cells in a telomere-specific fashion.
Title: Translin and Trax differentially regulate telomere-associated transcript homeostasis.

this study argues against a mechanism by which translin octamers may "dissociate and reassemble" upon RNA binding and report a novel "open"-barrel structure of human translin revealing a feasible DNA/RNA entryway into the cavity.
Title: A novel open-barrel structure of octameric translin reveals a potential RNA entryway.

These findings indicate that miRNA depletion in dicer deficiency is due to the combined loss of miRNA-generating activity and catabolic function of TN/TX.
Title: Rescuing dicer defects via inhibition of an anti-dicing nuclease.

The selectivity of PLCbeta toward certain genes lies in the rate at which the RNA is hydrolyzed by C3PO.
Title: Hydrolysis rates of different small interfering RNAs (siRNAs) by the RNA silencing promoter complex, C3PO, determines their regulation by phospholipase C?.

The following TSN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TSN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17266	NM_004622.3 Latest version!	Homo sapiens translin (TSN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20313	NM_001261401.1 Latest version!	Homo sapiens translin (TSN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu17266	NM_004622.2	Homo sapiens translin (TSN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TSN ( NM_004622.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004613.1 Homo sapiens translin (TSN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17266
Clone ID Related Accession (Same CDS sequence)	NM_004622.3 , NM_004622.2
Accession Version	NM_004622.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	translin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018737.9. On Nov 27, 2018 this sequence version replaced NM_004622.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.220308.1, SRR1803611.152473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000389682.8/ ENSP00000374332.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATTGAGCC AGATCGGGAG AAAGGATTTC ATCTGGATGT AGAAGATTAT 
CTCTCAGGAG TTCTAATTCT TGCCAGTGAA CTGTCGAGGC TGTCTGTCAA CAGCGTGACT 
GCTGGAGACT ACTCCCGACC CCTCCACATC TCCACCTTCA TCAATGAGCT GGATTCCGGT 
TTTCGCCTTC TCAACCTGAA AAATGACTCC CTGAGGAAGC GCTACGACGG ATTGAAATAT 
GACGTGAAGA AAGTAGAGGA AGTGGTCTAT GATCTCTCCA TCCGGGGCTT TAATAAGGAG 
ACGGCAGCAG CTTGTGTTGA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004613.1
CDS	130..816
Translation	MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACVEK

Target ORF information:

RefSeq Version	NM_004622.3
Organism	Homo sapiens(human)
Definition	Homo sapiens translin (TSN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004622.3

ORF Insert Sequence:

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATTGAGCC AGATCGGGAG AAAGGATTTC ATCTGGATGT AGAAGATTAT 
CTCTCAGGAG TTCTAATTCT TGCCAGTGAA CTGTCGAGGC TGTCTGTCAA CAGCGTGACT 
GCTGGAGACT ACTCCCGACC CCTCCACATC TCCACCTTCA TCAATGAGCT GGATTCCGGT 
TTTCGCCTTC TCAACCTGAA AAATGACTCC CTGAGGAAGC GCTACGACGG ATTGAAATAT 
GACGTGAAGA AAGTAGAGGA AGTGGTCTAT GATCTCTCCA TCCGGGGCTT TAATAAGGAG 
ACGGCAGCAG CTTGTGTTGA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TSN ( NM_004622.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004613.1 Homo sapiens translin (TSN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17266
Clone ID Related Accession (Same CDS sequence)	NM_004622.3 , NM_004622.2
Accession Version	NM_004622.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	translin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X78627.1, AL122099.1 and X95076.1. On Apr 24, 2002 this sequence version replaced NM_004622.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.170435.1, SRR1803611.54187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATTGAGCC AGATCGGGAG AAAGGATTTC ATCTGGATGT AGAAGATTAT 
CTCTCAGGAG TTCTAATTCT TGCCAGTGAA CTGTCGAGGC TGTCTGTCAA CAGCGTGACT 
GCTGGAGACT ACTCCCGACC CCTCCACATC TCCACCTTCA TCAATGAGCT GGATTCCGGT 
TTTCGCCTTC TCAACCTGAA AAATGACTCC CTGAGGAAGC GCTACGACGG ATTGAAATAT 
GACGTGAAGA AAGTAGAGGA AGTGGTCTAT GATCTCTCCA TCCGGGGCTT TAATAAGGAG 
ACGGCAGCAG CTTGTGTTGA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004613.1
CDS	236..922
Translation	MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACVEK

Target ORF information:

RefSeq Version	NM_004622.2
Organism	Homo sapiens(human)
Definition	Homo sapiens translin (TSN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004622.2

ORF Insert Sequence:

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATTGAGCC AGATCGGGAG AAAGGATTTC ATCTGGATGT AGAAGATTAT 
CTCTCAGGAG TTCTAATTCT TGCCAGTGAA CTGTCGAGGC TGTCTGTCAA CAGCGTGACT 
GCTGGAGACT ACTCCCGACC CCTCCACATC TCCACCTTCA TCAATGAGCT GGATTCCGGT 
TTTCGCCTTC TCAACCTGAA AAATGACTCC CTGAGGAAGC GCTACGACGG ATTGAAATAT 
GACGTGAAGA AAGTAGAGGA AGTGGTCTAT GATCTCTCCA TCCGGGGCTT TAATAAGGAG 
ACGGCAGCAG CTTGTGTTGA AAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TSN ( NM_001261401.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001248330.1 Homo sapiens translin (TSN), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20313
Clone ID Related Accession (Same CDS sequence)	NM_001261401.1
Accession Version	NM_001261401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	translin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA772798.1, AK296469.1, AK091915.1 and AL122099.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, compared to variant 1, which results in a frameshift and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.173065.1, SRR1660807.193402.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATCGAGGC TGTCTGTCAA CAGCGTGACT GCTGGAGACT ACTCCCGACC 
CCTCCACATC TCCACCTTCA TCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248330.1
CDS	236..682
Translation	MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEAVCQQRDCWRLLPTPPHLHLHQ

Target ORF information:

RefSeq Version	NM_001261401.1
Organism	Homo sapiens(human)
Definition	Homo sapiens translin (TSN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261401.1

ORF Insert Sequence:

ATGTCTGTGA GCGAGATCTT CGTGGAGCTG CAGGGCTTTT TGGCTGCCGA GCAGGACATC 
CGAGAGGAAA TCAGAAAAGT TGTACAGAGT TTAGAACAAA CAGCTCGAGA GATTTTAACT 
CTACTGCAAG GGGTCCATCA GGGTGCTGGG TTTCAGGACA TTCCAAAGAG GTGTTTGAAA 
GCTCGAGAAC ATTTTGGTAC AGTAAAAACA CATCTAACAT CTTTGAAGAC CAAATTTCCT 
GCTGAACAGT ATTACAGATT TCATGAGCAC TGGAGGTTTG TGTTGCAGCG CTTGGTCTTC 
TTGGCAGCAT TTGTTGTGTA TTTGGAAACA GAAACACTAG TGACTCGAGA AGCAGTTACA 
GAAATTCTTG GCATCGAGGC TGTCTGTCAA CAGCGTGACT GCTGGAGACT ACTCCCGACC 
CCTCCACATC TCCACCTTCA TCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

UPF1 helicase promotes TSN-mediated miRNA decay.
Genes & development31(14)1483-1493(2017 Jul)
Elbarbary RA,Miyoshi K,Hedaya O,Myers JR,Maquat LE

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Oncotarget7(23)33809-20(2016 Jun)
Gomez-Escobar N,Almobadel N,Alzahrani O,Feichtinger J,Planells-Palop V,Alshehri Z,Thallinger GG,Wakeman JA,McFarlane RJ

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

Rescuing dicer defects via inhibition of an anti-dicing nuclease.
Cell reports9(4)1471-81(2014 Nov)
Asada K,Canestrari E,Fu X,Li Z,Makowski E,Wu YC,Mito JK,Kirsch DG,Baraban J,Paroo Z

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TSN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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