Gene Symbol | TRPC6 |
Entrez Gene ID | 7225 |
Full Name | transient receptor potential cation channel subfamily C member 6 |
Synonyms | FSGS2,TRP6 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]. |
Disorder MIM: | |
Disorder Html: | Glomerulosclerosis, focal segmental, 2, 603965 (3) |