THPO gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001290003.1	NP_001276932.1	thrombopoietin isoform 5
NM_001177597.2	NP_001171068.1	thrombopoietin isoform 2 precursor
NM_001289998.1	NP_001276927.1	thrombopoietin isoform 1 precursor
NM_001289997.1	NP_001276926.1	thrombopoietin isoform 4 precursor
NM_001290028.1	NP_001276957.1	thrombopoietin isoform 1 precursor
NM_001290022.1	NP_001276951.1	thrombopoietin isoform 2 precursor
NM_001177598.2	NP_001171069.1	thrombopoietin isoform 3 precursor
NM_001290027.1	NP_001276956.1	thrombopoietin isoform 4 precursor
NM_001290026.1	NP_001276955.1	thrombopoietin isoform 3 precursor
NM_000460.3	NP_000451.1	thrombopoietin isoform 1 precursor
XM_017007107.1	XP_016862596.1	thrombopoietin isoform X1
NM_000460.4	NP_000451.1	thrombopoietin isoform 1 precursor

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02053	NM_001290022.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02053	NM_001177597.2 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10732	NM_000460.4 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10732	NM_001289998.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu10732	NM_001290028.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02030	NM_001290027.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu02030	NM_001289997.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu02046	NM_001290026.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu02046	NM_001177598.2 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu11385	NM_001290003.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu60994	XM_017007107.1 Latest version!	Homo sapiens thrombopoietin (THPO), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu10732	NM_000460.3	Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

THPO ( NM_001177597.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171068.1 Homo sapiens thrombopoietin (THPO), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02053
Clone ID Related Accession (Same CDS sequence)	NM_001177597.2 , NM_001290022.1
Accession Version	NM_001177597.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, L33410.1 and AA479058.1. On Feb 21, 2014 this sequence version replaced NM_001177597.1. Transcript Variant: This variant (2) represents use of the downstream promoter and comprises six exons. It uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC130322.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGTGCG TTTCCTGATG 
CTTGTAGGAG GGTCCACCCT CTGCGTCAGG CGGGCCCCAC CCACCACAGC TGTCCCCAGC 
AGAACCTCTC TAGTCCTCAC ACTGAACGAG CTCCCAAACA GGACTTCTGG ATTGTTGGAG 
ACAAACTTCA CTGCCTCAGC CAGAACTACT GGCTCTGGGC TTCTGAAGTG GCAGCAGGGA 
TTCAGAGCCA AGATTCCTGG TCTGCTGAAC CAAACCTCCA GGTCCCTGGA CCAAATCCCC 
GGATACCTGA ACAGGATACA CGAACTCTTG AATGGAACTC GTGGACTCTT TCCTGGACCC 
TCACGCAGGA CCCTAGGAGC CCCGGACATT TCCTCAGGAA CATCAGACAC AGGCTCCCTG 
CCACCCAACC TCCAGCCTGG ATATTCTCCT TCCCCAACCC ATCCTCCTAC TGGACAGTAT 
ACGCTCTTCC CTCTTCCACC CACCTTGCCC ACCCCTGTGG TCCAGCTCCA CCCCCTGCTT 
CCTGACCCTT CTGCTCCAAC GCCCACCCCT ACCAGCCCTC TTCTAAACAC ATCCTACACC 
CACTCCCAGA ATCTGTCTCA GGAAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171068.1
CDS	280..1329
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_001177597.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177597.2

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGTGCG TTTCCTGATG 
CTTGTAGGAG GGTCCACCCT CTGCGTCAGG CGGGCCCCAC CCACCACAGC TGTCCCCAGC 
AGAACCTCTC TAGTCCTCAC ACTGAACGAG CTCCCAAACA GGACTTCTGG ATTGTTGGAG 
ACAAACTTCA CTGCCTCAGC CAGAACTACT GGCTCTGGGC TTCTGAAGTG GCAGCAGGGA 
TTCAGAGCCA AGATTCCTGG TCTGCTGAAC CAAACCTCCA GGTCCCTGGA CCAAATCCCC 
GGATACCTGA ACAGGATACA CGAACTCTTG AATGGAACTC GTGGACTCTT TCCTGGACCC 
TCACGCAGGA CCCTAGGAGC CCCGGACATT TCCTCAGGAA CATCAGACAC AGGCTCCCTG 
CCACCCAACC TCCAGCCTGG ATATTCTCCT TCCCCAACCC ATCCTCCTAC TGGACAGTAT 
ACGCTCTTCC CTCTTCCACC CACCTTGCCC ACCCCTGTGG TCCAGCTCCA CCCCCTGCTT 
CCTGACCCTT CTGCTCCAAC GCCCACCCCT ACCAGCCCTC TTCTAAACAC ATCCTACACC 
CACTCCCAGA ATCTGTCTCA GGAAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001290022.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276951.1 Homo sapiens thrombopoietin (THPO), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu02053
Clone ID Related Accession (Same CDS sequence)	NM_001177597.2 , NM_001290022.1
Accession Version	NM_001290022.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, L33410.1 and AA479058.1. Transcript Variant: This variant (6) represents use of the upstream promoter and comprises seven exons. This variant is longer at the 5' end and has an alternate in-frame splice site in the 3' coding region, compared to variant 1. This variant includes two main in-frame AUG sites, but translation initiated from the upstream AUG codon for this variant is not reported in literature. The isoform (2) represented in this RefSeq is derived from the downstream AUG start codon; it is identical to the isoform encoded by variant 2 and lacks an internal segment, as compared to isoform 1. This variant was reported in PMID: 7822271. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC130322.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:7822271) regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGTGCG TTTCCTGATG 
CTTGTAGGAG GGTCCACCCT CTGCGTCAGG CGGGCCCCAC CCACCACAGC TGTCCCCAGC 
AGAACCTCTC TAGTCCTCAC ACTGAACGAG CTCCCAAACA GGACTTCTGG ATTGTTGGAG 
ACAAACTTCA CTGCCTCAGC CAGAACTACT GGCTCTGGGC TTCTGAAGTG GCAGCAGGGA 
TTCAGAGCCA AGATTCCTGG TCTGCTGAAC CAAACCTCCA GGTCCCTGGA CCAAATCCCC 
GGATACCTGA ACAGGATACA CGAACTCTTG AATGGAACTC GTGGACTCTT TCCTGGACCC 
TCACGCAGGA CCCTAGGAGC CCCGGACATT TCCTCAGGAA CATCAGACAC AGGCTCCCTG 
CCACCCAACC TCCAGCCTGG ATATTCTCCT TCCCCAACCC ATCCTCCTAC TGGACAGTAT 
ACGCTCTTCC CTCTTCCACC CACCTTGCCC ACCCCTGTGG TCCAGCTCCA CCCCCTGCTT 
CCTGACCCTT CTGCTCCAAC GCCCACCCCT ACCAGCCCTC TTCTAAACAC ATCCTACACC 
CACTCCCAGA ATCTGTCTCA GGAAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276951.1
CDS	547..1596
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_001290022.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290022.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGTGCG TTTCCTGATG 
CTTGTAGGAG GGTCCACCCT CTGCGTCAGG CGGGCCCCAC CCACCACAGC TGTCCCCAGC 
AGAACCTCTC TAGTCCTCAC ACTGAACGAG CTCCCAAACA GGACTTCTGG ATTGTTGGAG 
ACAAACTTCA CTGCCTCAGC CAGAACTACT GGCTCTGGGC TTCTGAAGTG GCAGCAGGGA 
TTCAGAGCCA AGATTCCTGG TCTGCTGAAC CAAACCTCCA GGTCCCTGGA CCAAATCCCC 
GGATACCTGA ACAGGATACA CGAACTCTTG AATGGAACTC GTGGACTCTT TCCTGGACCC 
TCACGCAGGA CCCTAGGAGC CCCGGACATT TCCTCAGGAA CATCAGACAC AGGCTCCCTG 
CCACCCAACC TCCAGCCTGG ATATTCTCCT TCCCCAACCC ATCCTCCTAC TGGACAGTAT 
ACGCTCTTCC CTCTTCCACC CACCTTGCCC ACCCCTGTGG TCCAGCTCCA CCCCCTGCTT 
CCTGACCCTT CTGCTCCAAC GCCCACCCCT ACCAGCCCTC TTCTAAACAC ATCCTACACC 
CACTCCCAGA ATCTGTCTCA GGAAGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001289998.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276927.1 Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu10732
Clone ID Related Accession (Same CDS sequence)	NM_001289998.1 , NM_001290028.1 , NM_000460.3 , NM_000460.4
Accession Version	NM_001289998.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, L33410.1, BC143982.1, BC136338.1 and AA479058.1. Transcript Variant: This variant (5) represents use of the upstream promoter and comprises seven exons. It is longer at the 5' end, compared to variant 1. This variant can initiate translation from two in-frame AUG sites. The isoform (1) represented in this Refseq is derived from the downstream AUG start codon and is identical to the isoform encoded by variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: L33410.1, D32047.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:7822271) regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276927.1
CDS	547..1608
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_001289998.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289998.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001290028.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276957.1 Homo sapiens thrombopoietin (THPO), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu10732
Clone ID Related Accession (Same CDS sequence)	NM_001289998.1 , NM_001290028.1 , NM_000460.3 , NM_000460.4
Accession Version	NM_001290028.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, L33410.1, BC143982.1, BC136338.1 and AA479058.1. Transcript Variant: This variant (9) represents use of the upstream promoter, but lacks an internal exon, compared to other transcripts with the same upstream promoter usage. This variant has an alternate 5' UTR exon and encodes the same isoform (1), compared to variant 1. This variant was reported in PMID: 9834204. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: L33410.1, D32047.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276957.1
CDS	244..1305
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_001290028.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290028.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_000460.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000451.1 Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.

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CloneID	OHu10732
Clone ID Related Accession (Same CDS sequence)	NM_001289998.1 , NM_001290028.1 , NM_000460.3 , NM_000460.4
Accession Version	NM_000460.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, L33410.1, BC143982.1, BC136338.1 and AA479058.1. This sequence is a reference standard in the RefSeqGene project. On Feb 21, 2014 this sequence version replaced NM_000460.2. Transcript Variant: This variant (1) represents use of the downstream promoter and comprises six exons. It encodes the main functional protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L33410.1, BC136338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000451.1
CDS	280..1341
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_000460.3
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000460.3

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_000460.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000451.1 Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.

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CloneID	OHu10732
Clone ID Related Accession (Same CDS sequence)	NM_001289998.1 , NM_001290028.1 , NM_000460.3 , NM_000460.4
Accession Version	NM_000460.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, L33410.1, BC143982.1, BC136338.1 and AA479058.1. This sequence is a reference standard in the RefSeqGene project. On May 9, 2018 this sequence version replaced NM_000460.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L33410.1, SRR5189664.158503.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000451.1
CDS	279..1340
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_000460.4
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000460.4

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001289997.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276926.1 Homo sapiens thrombopoietin (THPO), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu02030
Clone ID Related Accession (Same CDS sequence)	NM_001289997.1 , NM_001290027.1
Accession Version	NM_001289997.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, AK311002.1, U11025.1, L33410.1 and AA479058.1. Transcript Variant: This variant (4) represents use of the downstream promoter and comprises six exons. It lacks an internal segment in the 3' exon, which results in a frameshift, compared to variant 1. The resulting isoform (4) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGAC 
TTCTGGATTG TTGGAGACAA ACTTCACTGC CTCAGCCAGA ACTACTGGCT CTGGGCTTCT 
GAAGTGGCAG CAGGGATTCA GAGCCAAGAT TCCTGGTCTG CTGAACCAAA CCTCCAGGTC 
CCTGGACCAA ATCCCCGGAT ACCTGAACAG GATACACGAA CTCTTGAATG GAACTCGTGG 
ACTCTTTCCT GGACCCTCAC GCAGGACCCT AGGAGCCCCG GACATTTCCT CAGGAACATC 
AGACACAGGC TCCCTGCCAC CCAACCTCCA GCCTGGATAT TCTCCTTCCC CAACCCATCC 
TCCTACTGGA CAGTATACGC TCTTCCCTCT TCCACCCACC TTGCCCACCC CTGTGGTCCA 
GCTCCACCCC CTGCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276926.1
CDS	280..1140
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPAS

Target ORF information:

RefSeq Version	NM_001289997.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289997.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGAC 
TTCTGGATTG TTGGAGACAA ACTTCACTGC CTCAGCCAGA ACTACTGGCT CTGGGCTTCT 
GAAGTGGCAG CAGGGATTCA GAGCCAAGAT TCCTGGTCTG CTGAACCAAA CCTCCAGGTC 
CCTGGACCAA ATCCCCGGAT ACCTGAACAG GATACACGAA CTCTTGAATG GAACTCGTGG 
ACTCTTTCCT GGACCCTCAC GCAGGACCCT AGGAGCCCCG GACATTTCCT CAGGAACATC 
AGACACAGGC TCCCTGCCAC CCAACCTCCA GCCTGGATAT TCTCCTTCCC CAACCCATCC 
TCCTACTGGA CAGTATACGC TCTTCCCTCT TCCACCCACC TTGCCCACCC CTGTGGTCCA 
GCTCCACCCC CTGCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001290027.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276956.1 Homo sapiens thrombopoietin (THPO), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu02030
Clone ID Related Accession (Same CDS sequence)	NM_001289997.1 , NM_001290027.1
Accession Version	NM_001290027.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, AK311002.1, U11025.1, L33410.1 and AA479058.1. Transcript Variant: This variant (8) represents use of the upstream promoter and comprises seven exons. It includes two main in-frame AUG sites, but translation initiated from the upstream AUG codon for this variant is not reported in literature. The isoform (4) represented in this RefSeq is derived from the downstream AUG start codon; it is identical to the isoform encoded by variant 4 and lacks an internal segment, as compared to isoform 1. This variant was reported in PMID: 7822271. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:7822271) regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGAC 
TTCTGGATTG TTGGAGACAA ACTTCACTGC CTCAGCCAGA ACTACTGGCT CTGGGCTTCT 
GAAGTGGCAG CAGGGATTCA GAGCCAAGAT TCCTGGTCTG CTGAACCAAA CCTCCAGGTC 
CCTGGACCAA ATCCCCGGAT ACCTGAACAG GATACACGAA CTCTTGAATG GAACTCGTGG 
ACTCTTTCCT GGACCCTCAC GCAGGACCCT AGGAGCCCCG GACATTTCCT CAGGAACATC 
AGACACAGGC TCCCTGCCAC CCAACCTCCA GCCTGGATAT TCTCCTTCCC CAACCCATCC 
TCCTACTGGA CAGTATACGC TCTTCCCTCT TCCACCCACC TTGCCCACCC CTGTGGTCCA 
GCTCCACCCC CTGCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276956.1
CDS	547..1407
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPAS

Target ORF information:

RefSeq Version	NM_001290027.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290027.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGAC 
TTCTGGATTG TTGGAGACAA ACTTCACTGC CTCAGCCAGA ACTACTGGCT CTGGGCTTCT 
GAAGTGGCAG CAGGGATTCA GAGCCAAGAT TCCTGGTCTG CTGAACCAAA CCTCCAGGTC 
CCTGGACCAA ATCCCCGGAT ACCTGAACAG GATACACGAA CTCTTGAATG GAACTCGTGG 
ACTCTTTCCT GGACCCTCAC GCAGGACCCT AGGAGCCCCG GACATTTCCT CAGGAACATC 
AGACACAGGC TCCCTGCCAC CCAACCTCCA GCCTGGATAT TCTCCTTCCC CAACCCATCC 
TCCTACTGGA CAGTATACGC TCTTCCCTCT TCCACCCACC TTGCCCACCC CTGTGGTCCA 
GCTCCACCCC CTGCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001177598.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171069.1 Homo sapiens thrombopoietin (THPO), transcript variant 3, mRNA.

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CloneID	OHu02046
Clone ID Related Accession (Same CDS sequence)	NM_001177598.2 , NM_001290026.1
Accession Version	NM_001177598.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, AB102890.1, AA480029.1 and AA479058.1. On Feb 21, 2014 this sequence version replaced NM_001177598.1. Transcript Variant: This variant (3) represents use of the downstream promoter and comprises six exons. It uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB102890.1 [ECO:0000331] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGACC ACAGCTCACA AGGATCCCAA 
TGCCATCTTC CTGAGCTTCC AACACCTGCT CCGAGGAAAG GTGCGTTTCC TGATGCTTGT 
AGGAGGGTCC ACCCTCTGCG TCAGGCGGGC CCCACCCACC ACAGCTGTCC CCAGCAGAAC 
CTCTCTAGTC CTCACACTGA ACGAGCTCCC AAACAGGACT TCTGGATTGT TGGAGACAAA 
CTTCACTGCC TCAGCCAGAA CTACTGGCTC TGGGCTTCTG AAGTGGCAGC AGGGATTCAG 
AGCCAAGATT CCTGGTCTGC TGAACCAAAC CTCCAGGTCC CTGGACCAAA TCCCCGGATA 
CCTGAACAGG ATACACGAAC TCTTGAATGG AACTCGTGGA CTCTTTCCTG GACCCTCACG 
CAGGACCCTA GGAGCCCCGG ACATTTCCTC AGGAACATCA GACACAGGCT CCCTGCCACC 
CAACCTCCAG CCTGGATATT CTCCTTCCCC AACCCATCCT CCTACTGGAC AGTATACGCT 
CTTCCCTCTT CCACCCACCT TGCCCACCCC TGTGGTCCAG CTCCACCCCC TGCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171069.1
CDS	280..1239
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQDHSSQGSQCHLPELPTPAPRKGAFPDACRRVHPLRQAGPTHHSCPQQNLSSPHTERAPKQDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPAS

Target ORF information:

RefSeq Version	NM_001177598.2
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177598.2

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGACC ACAGCTCACA AGGATCCCAA 
TGCCATCTTC CTGAGCTTCC AACACCTGCT CCGAGGAAAG GTGCGTTTCC TGATGCTTGT 
AGGAGGGTCC ACCCTCTGCG TCAGGCGGGC CCCACCCACC ACAGCTGTCC CCAGCAGAAC 
CTCTCTAGTC CTCACACTGA ACGAGCTCCC AAACAGGACT TCTGGATTGT TGGAGACAAA 
CTTCACTGCC TCAGCCAGAA CTACTGGCTC TGGGCTTCTG AAGTGGCAGC AGGGATTCAG 
AGCCAAGATT CCTGGTCTGC TGAACCAAAC CTCCAGGTCC CTGGACCAAA TCCCCGGATA 
CCTGAACAGG ATACACGAAC TCTTGAATGG AACTCGTGGA CTCTTTCCTG GACCCTCACG 
CAGGACCCTA GGAGCCCCGG ACATTTCCTC AGGAACATCA GACACAGGCT CCCTGCCACC 
CAACCTCCAG CCTGGATATT CTCCTTCCCC AACCCATCCT CCTACTGGAC AGTATACGCT 
CTTCCCTCTT CCACCCACCT TGCCCACCCC TGTGGTCCAG CTCCACCCCC TGCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001290026.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276955.1 Homo sapiens thrombopoietin (THPO), transcript variant 7, mRNA.

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CloneID	OHu02046
Clone ID Related Accession (Same CDS sequence)	NM_001177598.2 , NM_001290026.1
Accession Version	NM_001290026.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, BC143982.1, AB102890.1, AA480029.1 and AA479058.1. Transcript Variant: This variant (7) represents use of the upstream promoter and comprises seven exons. This variant is longer at the 5' end and has an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. This variant includes two main in-frame AUG sites, but translation initiated from the upstream AUG codon for this variant is not reported in literature. The isoform (3) represented in this RefSeq is derived from the downstream AUG start codon; it is identical to the isoform encoded by variant 3 and lacks an internal segment, as compared to isoform 1. This variant was reported in PMID: 7822271. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB102890.1 [ECO:0000331] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:7822271) regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGACC ACAGCTCACA AGGATCCCAA 
TGCCATCTTC CTGAGCTTCC AACACCTGCT CCGAGGAAAG GTGCGTTTCC TGATGCTTGT 
AGGAGGGTCC ACCCTCTGCG TCAGGCGGGC CCCACCCACC ACAGCTGTCC CCAGCAGAAC 
CTCTCTAGTC CTCACACTGA ACGAGCTCCC AAACAGGACT TCTGGATTGT TGGAGACAAA 
CTTCACTGCC TCAGCCAGAA CTACTGGCTC TGGGCTTCTG AAGTGGCAGC AGGGATTCAG 
AGCCAAGATT CCTGGTCTGC TGAACCAAAC CTCCAGGTCC CTGGACCAAA TCCCCGGATA 
CCTGAACAGG ATACACGAAC TCTTGAATGG AACTCGTGGA CTCTTTCCTG GACCCTCACG 
CAGGACCCTA GGAGCCCCGG ACATTTCCTC AGGAACATCA GACACAGGCT CCCTGCCACC 
CAACCTCCAG CCTGGATATT CTCCTTCCCC AACCCATCCT CCTACTGGAC AGTATACGCT 
CTTCCCTCTT CCACCCACCT TGCCCACCCC TGTGGTCCAG CTCCACCCCC TGCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276955.1
CDS	547..1506
Translation	MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQDHSSQGSQCHLPELPTPAPRKGAFPDACRRVHPLRQAGPTHHSCPQQNLSSPHTERAPKQDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPAS

Target ORF information:

RefSeq Version	NM_001290026.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290026.1

ORF Insert Sequence:

ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGACC ACAGCTCACA AGGATCCCAA 
TGCCATCTTC CTGAGCTTCC AACACCTGCT CCGAGGAAAG GTGCGTTTCC TGATGCTTGT 
AGGAGGGTCC ACCCTCTGCG TCAGGCGGGC CCCACCCACC ACAGCTGTCC CCAGCAGAAC 
CTCTCTAGTC CTCACACTGA ACGAGCTCCC AAACAGGACT TCTGGATTGT TGGAGACAAA 
CTTCACTGCC TCAGCCAGAA CTACTGGCTC TGGGCTTCTG AAGTGGCAGC AGGGATTCAG 
AGCCAAGATT CCTGGTCTGC TGAACCAAAC CTCCAGGTCC CTGGACCAAA TCCCCGGATA 
CCTGAACAGG ATACACGAAC TCTTGAATGG AACTCGTGGA CTCTTTCCTG GACCCTCACG 
CAGGACCCTA GGAGCCCCGG ACATTTCCTC AGGAACATCA GACACAGGCT CCCTGCCACC 
CAACCTCCAG CCTGGATATT CTCCTTCCCC AACCCATCCT CCTACTGGAC AGTATACGCT 
CTTCCCTCTT CCACCCACCT TGCCCACCCC TGTGGTCCAG CTCCACCCCC TGCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( NM_001290003.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276932.1 Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.

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CloneID	OHu11385
Clone ID Related Accession (Same CDS sequence)	NM_001290003.1
Accession Version	NM_001290003.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	thrombopoietin isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC078797.20, L33410.1, BC143982.1, BC136338.1 and AA479058.1. Transcript Variant: This variant (5) represents use of the upstream promoter and comprises seven exons. It is longer at the 5' end, compared to variant 1. This variant can initiate translation from two in-frame AUG sites. The isoform (5) represented in this Refseq is derived from the upstream AUG start codon and is longer at the N-terminus, compared to isoform 1. This isoform was described as a uAUG4 product in PMID: 9834204 and had no thrombopoietin bioactivity. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 9834204 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATCCCC CTATCCAAAT CTTCTCCGTG GTGTGTGTGG GTGGAGGAGT GGACCCTGGT 
CCAGGCAGGG GCTCCAGGGA AGAGAAGGCG TCACTTCCGG GGGCCTTCAC CAGTGTCTGG 
TGGCTCCCTT CTCTGATTGG GCAGAAGTGG CCCAGGCAGG CGTATGACCT GCTGCTGTGG 
AGGGGCTGTG CCCCACCGCC ACATGTCTTC CTACCCATCT GCTCCCCAGA GGGCTGCCTG 
CTGTGCACTT GGGTCCTGGA GCCCTTCTCC ACCCGGATAG ATTCTTCACC CTTGGCCCGC 
CTTTGCCCCA CCCTACTCTG CCCAGAAGTG CAAGAGCCTA AGCCGCCTCC ATGGCCCCAG 
GAAGGATTCA GGGGAGAGGC CCCAAACAGG GAGCCACGCC AGCCAGACAC CCCGGCCAGA 
ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276932.1
CDS	127..1608
Translation	MDPPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFTSVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSPLARLCPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG

Target ORF information:

RefSeq Version	NM_001290003.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290003.1

ORF Insert Sequence:

ATGGATCCCC CTATCCAAAT CTTCTCCGTG GTGTGTGTGG GTGGAGGAGT GGACCCTGGT 
CCAGGCAGGG GCTCCAGGGA AGAGAAGGCG TCACTTCCGG GGGCCTTCAC CAGTGTCTGG 
TGGCTCCCTT CTCTGATTGG GCAGAAGTGG CCCAGGCAGG CGTATGACCT GCTGCTGTGG 
AGGGGCTGTG CCCCACCGCC ACATGTCTTC CTACCCATCT GCTCCCCAGA GGGCTGCCTG 
CTGTGCACTT GGGTCCTGGA GCCCTTCTCC ACCCGGATAG ATTCTTCACC CTTGGCCCGC 
CTTTGCCCCA CCCTACTCTG CCCAGAAGTG CAAGAGCCTA AGCCGCCTCC ATGGCCCCAG 
GAAGGATTCA GGGGAGAGGC CCCAAACAGG GAGCCACGCC AGCCAGACAC CCCGGCCAGA 
ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGCTTC CTCCACAGGG CAGGACCACA 
GCTCACAAGG ATCCCAATGC CATCTTCCTG AGCTTCCAAC ACCTGCTCCG AGGAAAGGTG 
CGTTTCCTGA TGCTTGTAGG AGGGTCCACC CTCTGCGTCA GGCGGGCCCC ACCCACCACA 
GCTGTCCCCA GCAGAACCTC TCTAGTCCTC ACACTGAACG AGCTCCCAAA CAGGACTTCT 
GGATTGTTGG AGACAAACTT CACTGCCTCA GCCAGAACTA CTGGCTCTGG GCTTCTGAAG 
TGGCAGCAGG GATTCAGAGC CAAGATTCCT GGTCTGCTGA ACCAAACCTC CAGGTCCCTG 
GACCAAATCC CCGGATACCT GAACAGGATA CACGAACTCT TGAATGGAAC TCGTGGACTC 
TTTCCTGGAC CCTCACGCAG GACCCTAGGA GCCCCGGACA TTTCCTCAGG AACATCAGAC 
ACAGGCTCCC TGCCACCCAA CCTCCAGCCT GGATATTCTC CTTCCCCAAC CCATCCTCCT 
ACTGGACAGT ATACGCTCTT CCCTCTTCCA CCCACCTTGC CCACCCCTGT GGTCCAGCTC 
CACCCCCTGC TTCCTGACCC TTCTGCTCCA ACGCCCACCC CTACCAGCCC TCTTCTAAAC 
ACATCCTACA CCCACTCCCA GAATCTGTCT CAGGAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THPO ( XM_017007107.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862596.1 Homo sapiens thrombopoietin (THPO), transcript variant X1, mRNA.

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CloneID	OHu60994
Clone ID Related Accession (Same CDS sequence)	XM_017007107.1
Accession Version	XM_017007107.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	thrombopoietin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCCCC CTATCCAAAT CTTCTCCGTG GTGTGTGTGG GTGGAGGAGT GGACCCTGGT 
CCAGGCAGGG GCTCCAGGGA AGAGAAGGCG TCACTTCCGG GGGCCTTCAC CAGTGTCTGG 
TGGCTCCCTT CTCTGATTGG GCAGAAGTGG CCCAGGCAGG CGTATGACCT GCTGCTGTGG 
AGGGGCTGTG CCCCACCGCC ACATGTCTTC CTACCCATCT GCTCCCCAGA GGGCTGCCTG 
CTGTGCACTT GGGTCCTGGA GCCCTTCTCC ACCCGGATAG ATTCTTCACC CTTGGCCCGC 
CTTTGCCCCA CCCTACTCTG CCCAGAAGTG CAAGAGCCTA AGCCGCCTCC ATGGCCCCAG 
GAAGGATTCA GGGGAGAGGC CCCAAACAGG GAGCCACGCC AGCCAGACAC CCCGGCCAGA 
ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGACTT CTGGATTGTT 
GGAGACAAAC TTCACTGCCT CAGCCAGAAC TACTGGCTCT GGGCTTCTGA AGTGGCAGCA 
GGGATTCAGA GCCAAGATTC CTGGTCTGCT GAACCAAACC TCCAGGTCCC TGGACCAAAT 
CCCCGGATAC CTGAACAGGA TACACGAACT CTTGAATGGA ACTCGTGGAC TCTTTCCTGG 
ACCCTCACGC AGGACCCTAG GAGCCCCGGA CATTTCCTCA GGAACATCAG ACACAGGCTC 
CCTGCCACCC AACCTCCAGC CTGGATATTC TCCTTCCCCA ACCCATCCTC CTACTGGACA 
GTATACGCTC TTCCCTCTTC CACCCACCTT GCCCACCCCT GTGGTCCAGC TCCACCCCCT 
GCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862596.1
CDS	127..1395
Translation	MDPPIQIFSVVCVGGGVDPGPGRGSREEKASLPGAFTSVWWLPSLIGQKWPRQAYDLLLWRGCAPPPHVFLPICSPEGCLLCTWVLEPFSTRIDSSPLARLCPTLLCPEVQEPKPPPWPQEGFRGEAPNREPRQPDTPARMELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQGRTTAHKDPNAIFLSFQHLLRGKDFWIVGDKLHCLSQNYWLWASEVAAGIQSQDSWSAEPNLQVPGPNPRIPEQDTRTLEWNSWTLSWTLTQDPRSPGHFLRNIRHRLPATQPPAWIFSFPNPSSYWTVYALPSSTHLAHPCGPAPPPAS

Target ORF information:

RefSeq Version	XM_017007107.1
Organism	Homo sapiens(human)
Definition	Homo sapiens thrombopoietin (THPO), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007107.1

ORF Insert Sequence:

ATGGATCCCC CTATCCAAAT CTTCTCCGTG GTGTGTGTGG GTGGAGGAGT GGACCCTGGT 
CCAGGCAGGG GCTCCAGGGA AGAGAAGGCG TCACTTCCGG GGGCCTTCAC CAGTGTCTGG 
TGGCTCCCTT CTCTGATTGG GCAGAAGTGG CCCAGGCAGG CGTATGACCT GCTGCTGTGG 
AGGGGCTGTG CCCCACCGCC ACATGTCTTC CTACCCATCT GCTCCCCAGA GGGCTGCCTG 
CTGTGCACTT GGGTCCTGGA GCCCTTCTCC ACCCGGATAG ATTCTTCACC CTTGGCCCGC 
CTTTGCCCCA CCCTACTCTG CCCAGAAGTG CAAGAGCCTA AGCCGCCTCC ATGGCCCCAG 
GAAGGATTCA GGGGAGAGGC CCCAAACAGG GAGCCACGCC AGCCAGACAC CCCGGCCAGA 
ATGGAGCTGA CTGAATTGCT CCTCGTGGTC ATGCTTCTCC TAACTGCAAG GCTAACGCTG 
TCCAGCCCGG CTCCTCCTGC TTGTGACCTC CGAGTCCTCA GTAAACTGCT TCGTGACTCC 
CATGTCCTTC ACAGCAGACT GAGCCAGTGC CCAGAGGTTC ACCCTTTGCC TACACCTGTC 
CTGCTGCCTG CTGTGGACTT TAGCTTGGGA GAATGGAAAA CCCAGATGGA GGAGACCAAG 
GCACAGGACA TTCTGGGAGC AGTGACCCTT CTGCTGGAGG GAGTGATGGC AGCACGGGGA 
CAACTGGGAC CCACTTGCCT CTCATCCCTC CTGGGGCAGC TTTCTGGACA GGTCCGTCTC 
CTCCTTGGGG CCCTGCAGAG CCTCCTTGGA ACCCAGGGCA GGACCACAGC TCACAAGGAT 
CCCAATGCCA TCTTCCTGAG CTTCCAACAC CTGCTCCGAG GAAAGGACTT CTGGATTGTT 
GGAGACAAAC TTCACTGCCT CAGCCAGAAC TACTGGCTCT GGGCTTCTGA AGTGGCAGCA 
GGGATTCAGA GCCAAGATTC CTGGTCTGCT GAACCAAACC TCCAGGTCCC TGGACCAAAT 
CCCCGGATAC CTGAACAGGA TACACGAACT CTTGAATGGA ACTCGTGGAC TCTTTCCTGG 
ACCCTCACGC AGGACCCTAG GAGCCCCGGA CATTTCCTCA GGAACATCAG ACACAGGCTC 
CCTGCCACCC AACCTCCAGC CTGGATATTC TCCTTCCCCA ACCCATCCTC CTACTGGACA 
GTATACGCTC TTCCCTCTTC CACCCACCTT GCCCACCCCT GTGGTCCAGC TCCACCCCCT 
GCTTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	THPO
Entrez Gene ID	7066
Full Name	thrombopoietin
Synonyms	MGDF,MKCSF,ML,MPLLG,THCYT1,TPO
General protein information	Preferred Names thrombopoietin Names thrombopoietin MPL ligand c-mpl ligand megakaryocyte colony-stimulating factor megakaryocyte growth and development factor megakaryocyte stimulating factor myeloproliferative leukemia virus oncogene ligand prepro-thrombopoietin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.1
Summary	Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014].
Disorder MIM:	600044
Disorder Html:	Thrombocythemia 1, 187950 (3)

Mus musculus (house mouse)	Thpo	NP_033405.1
Bos taurus (cattle)	THPO	NP_001159512.1
Rattus norvegicus (Norway rat)	LOC100910397	XP_006248642.1
Pan troglodytes (chimpanzee)	THPO	XP_001136518.2
Rattus norvegicus (Norway rat)	Thpo	NP_112395.1
Homo sapiens (human)	THPO	NP_000451.1
Canis lupus familiaris (dog)	THPO	XP_005639837.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

THPO cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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