Gene Symbol | THOP1 |
Entrez Gene ID | 7064 |
Full Name | thimet oligopeptidase 1 |
Synonyms | EP24.15,MEPD_HUMAN,MP78,TOP |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]. |
Disorder MIM: |