TGM4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TGM4
Entrez Gene ID	7047
Full Name	transglutaminase 4
Synonyms	TGP,hTGP
General protein information	Preferred Names transglutaminase 4 Names protein-glutamine gamma-glutamyltransferase 4 TG(P) TGase P TGase-4 fibrinoligase prostate transglutaminase prostate-specific transglutaminase transglutaminase 4 (prostate) transglutaminase P
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Disorder MIM:	600585

mRNA and Protein(s)

mRNA	Protein	Name
XM_011534042.1	XP_011532344.1	protein-glutamine gamma-glutamyltransferase 4 isoform X1
NM_003241.3	NP_003232.2	protein-glutamine gamma-glutamyltransferase 4
XM_011534042.2	XP_011532344.1	protein-glutamine gamma-glutamyltransferase 4 isoform X1
NM_003241.4	NP_003232.2	protein-glutamine gamma-glutamyltransferase 4

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tgm4	NP_808579.2
Rattus norvegicus (Norway rat)	Tgm4	NP_073204.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009098	XP_319848.5
Pan troglodytes (chimpanzee)	TGM4	NP_001124381.1
Xenopus tropicalis (tropical clawed frog)	LOC100488471	XP_002937793.2
	TGM4	XP_002808372.1
Gallus gallus (chicken)	TGM4	NP_001006368.1
Homo sapiens (human)	TGM4	NP_003232.2
Xenopus tropicalis (tropical clawed frog)	tgm4	XP_002937794.2

Gene Ontology
Bibliography

Related articles in PubMed

Transglutaminase 4 as a prostate autoantigen in male subfertility.
Landegren N, Sharon D, Shum AK, Khan IS, Fasano KJ, Hallgren ?, Kampf C, Freyhult E, Ardesj?-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, K?mpe O
Science translational medicine7(292)292ra101(2015 Jun)

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Navarini AA, Simpson MA, Weale M, Knight J, Carlavan I, Reiniche P, Burden DA, Layton A, Bataille V, Allen M, Pleass R, Pink A, Creamer D, English J, Munn S, Walton S, , Willis C, D?ret S, Voegel JJ, Spector T, Smith CH, Trembath RC, Barker JN
Nature communications54020(2014 Jun)

Overexpression of transglutaminase 4 and prostate cancer progression: a potential predictor of less favourable outcomes.
Cao Z, Wang Y, Liu ZY, Zhang ZS, Ren SC, Yu YW, Qiao M, Zhai BB, Sun YH
Asian journal of andrology15(6)742-6(2013 Nov)

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.
Rivera-Gonzalez GC, Droop AP, Rippon HJ, Tiemann K, Pellacani D, Georgopoulos LJ, Maitland NJ
Nucleic acids research40(11)4825-40(2012 Jun)

Analysis of laser-microdissected prostate cancer tissues reveals potential tumor markers.
Shaikhibrahim Z, Lindstrot A, Buettner R, Wernert N
International journal of molecular medicine28(4)605-11(2011 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGM4 is a prostatic secretory molecule with critical role in male reproduction.
Title: Transglutaminase 4 as a prostate autoantigen in male subfertility.

indicated that transglutaminase 4 may serve as a potential predictor of biochemical recurrence of prostate cancer
Title: Overexpression of transglutaminase 4 and prostate cancer progression: a potential predictor of less favourable outcomes.

Evidence that the retinoic acid receptor gamma plays a major role in the regulation of the hTGP gene and that presence of the androgen receptor, but not its transcriptional transactivation activity, is critical for hTGP transcription.
Title: Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.

CDKN2A, GATA3, CREBBP, ITGA2, NBL1 and TGM4 were down-regulated in the prostate carcinoma glands compared to the corresponding normal glands
Title: Analysis of laser-microdissected prostate cancer tissues reveals potential tumor markers.

The presence of TGase-4 has a biological impact on a prostate cancer cell's response to MDA-7.
Title: Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer.

The following TGM4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGM4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30658	NM_003241.4 Latest version!	Homo sapiens transglutaminase 4 (TGM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu60977	XM_011534042.2 Latest version!	Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu60977	XM_011534042.1	Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu30658	NM_003241.3	Homo sapiens transglutaminase 4 (TGM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TGM4 ( NM_003241.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003232.2 Homo sapiens transglutaminase 4 (TGM4), mRNA.

Price & Availability↑

CloneID	OHu30658
Clone ID Related Accession (Same CDS sequence)	NM_003241.3 , NM_003241.4
Accession Version	NM_003241.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA870110.1, L34840.1, BF678064.1, BC007003.1 and AC098649.2. On May 17, 2019 this sequence version replaced NM_003241.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312936.1, BC007003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146411, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296125.9/ ENSP00000296125.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGATGGATG CATCAAAAGA GCTGCAAGTT CTCCACATTG ACTTCTTGAA TCAGGACAAC 
GCCGTTTCTC ACCACACATG GGAGTTCCAA ACGAGCAGTC CTGTGTTCCG GCGAGGACAG 
GTGTTTCACC TGCGGCTGGT GCTGAACCAG CCCCTACAAT CCTACCACCA ACTGAAACTG 
GAATTCAGCA CAGGGCCGAA TCCTAGCATC GCCAAACACA CCCTGGTGGT GCTCGACCCG 
AGGACGCCCT CAGACCACTA CAACTGGCAG GCAACCCTTC AAAATGAGTC TGGCAAAGAG 
GTCACAGTGG CTGTCACCAG TTCCCCCAAT GCCATCCTGG GCAAGTACCA ACTAAACGTG 
AAAACTGGAA ACCACATCCT TAAGTCTGAA GAAAACATCC TATACCTTCT CTTCAACCCA 
TGGTGTAAAG AGGACATGGT TTTCATGCCT GATGAGGACG AGCGCAAAGA GTACATCCTC 
AATGACACGG GCTGCCATTA CGTGGGGGCT GCCAGAAGTA TCAAATGCAA ACCCTGGAAC 
TTTGGTCAGT TTGAGAAAAA TGTCCTGGAC TGCTGCATTT CCCTGCTGAC TGAGAGCTCC 
CTCAAGCCCA CAGATAGGAG GGACCCCGTG CTGGTGTGCA GGGCCATGTG TGCTATGATG 
AGCTTTGAGA AAGGCCAGGG CGTGCTCATT GGGAATTGGA CTGGGGACTA CGAAGGTGGC 
ACAGCCCCAT ACAAGTGGAC AGGCAGTGCC CCGATCCTGC AGCAGTACTA CAACACGAAG 
CAGGCTGTGT GCTTTGGCCA GTGCTGGGTG TTTGCTGGGA TCCTGACTAC AGTGCTGAGA 
GCGTTGGGCA TCCCAGCACG CAGTGTGACA GGCTTCGATT CAGCTCACGA CACAGAAAGG 
AACCTCACGG TGGACACCTA TGTGAATGAG AATGGCGAGA AAATCACCAG TATGACCCAC 
GACTCTGTCT GGAATTTCCA TGTGTGGACG GATGCCTGGA TGAAGCGACC GGATCTGCCC 
AAGGGCTACG ACGGCTGGCA GGCTGTGGAC GCAACGCCGC AGGAGCGAAG CCAGGGTGTC 
TTCTGCTGTG GGCCATCACC ACTGACCGCC ATCCGCAAAG GTGACATCTT TATTGTCTAT 
GACACCAGAT TCGTCTTCTC AGAAGTGAAT GGTGACAGGC TCATCTGGTT GGTGAAGATG 
GTGAATGGGC AGGAGGAGTT ACACGTAATT TCAATGGAGA CCACAAGCAT CGGGAAAAAC 
ATCAGCACCA AGGCAGTGGG CCAAGACAGG CGGAGAGATA TCACCTATGA GTACAAGTAT 
CCAGAAGGCT CCTCTGAGGA GAGGCAGGTC ATGGATCATG CCTTCCTCCT TCTCAGTTCT 
GAGAGGGAGC ACAGACGACC TGTAAAAGAG AACTTTCTTC ACATGTCGGT ACAATCAGAT 
GATGTGCTGC TGGGAAACTC TGTTAATTTC ACCGTGATTC TTAAAAGGAA GACCGCTGCC 
CTACAGAATG TCAACATCTT GGGCTCCTTT GAACTACAGT TGTACACTGG CAAGAAGATG 
GCAAAACTGT GTGACCTCAA TAAGACCTCG CAGATCCAAG GTCAAGTATC AGAAGTGACT 
CTGACCTTGG ACTCCAAGAC CTACATCAAC AGCCTGGCTA TATTAGATGA TGAGCCAGTT 
ATCAGAGGTT TCATCATTGC GGAAATTGTG GAGTCTAAGG AAATCATGGC CTCTGAAGTA 
TTCACGTCTT TCCAGTACCC TGAGTTCTCT ATAGAGTTGC CTAACACAGG CAGAATTGGC 
CAGCTACTTG TCTGCAATTG TATCTTCAAG AATACCCTGG CCATCCCTTT GACTGACGTC 
AAGTTCTCTT TGGAAAGCCT GGGCATCTCC TCACTACAGA CCTCTGACCA TGGGACGGTG 
CAGCCTGGTG AGACCATCCA ATCCCAAATA AAATGCACCC CAATAAAAAC TGGACCCAAG 
AAATTTATCG TCAAGTTAAG TTCCAAACAA GTGAAAGAGA TTAATGCTCA GAAGATTGTT 
CTCATCACCA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003232.2
CDS	72..2126
Translation	MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK

Target ORF information:

RefSeq Version	NM_003241.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 4 (TGM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003241.4

ORF Insert Sequence:

ATGATGGATG CATCAAAAGA GCTGCAAGTT CTCCACATTG ACTTCTTGAA TCAGGACAAC 
GCCGTTTCTC ACCACACATG GGAGTTCCAA ACGAGCAGTC CTGTGTTCCG GCGAGGACAG 
GTGTTTCACC TGCGGCTGGT GCTGAACCAG CCCCTACAAT CCTACCACCA ACTGAAACTG 
GAATTCAGCA CAGGGCCGAA TCCTAGCATC GCCAAACACA CCCTGGTGGT GCTCGACCCG 
AGGACGCCCT CAGACCACTA CAACTGGCAG GCAACCCTTC AAAATGAGTC TGGCAAAGAG 
GTCACAGTGG CTGTCACCAG TTCCCCCAAT GCCATCCTGG GCAAGTACCA ACTAAACGTG 
AAAACTGGAA ACCACATCCT TAAGTCTGAA GAAAACATCC TATACCTTCT CTTCAACCCA 
TGGTGTAAAG AGGACATGGT TTTCATGCCT GATGAGGACG AGCGCAAAGA GTACATCCTC 
AATGACACGG GCTGCCATTA CGTGGGGGCT GCCAGAAGTA TCAAATGCAA ACCCTGGAAC 
TTTGGTCAGT TTGAGAAAAA TGTCCTGGAC TGCTGCATTT CCCTGCTGAC TGAGAGCTCC 
CTCAAGCCCA CAGATAGGAG GGACCCCGTG CTGGTGTGCA GGGCCATGTG TGCTATGATG 
AGCTTTGAGA AAGGCCAGGG CGTGCTCATT GGGAATTGGA CTGGGGACTA CGAAGGTGGC 
ACAGCCCCAT ACAAGTGGAC AGGCAGTGCC CCGATCCTGC AGCAGTACTA CAACACGAAG 
CAGGCTGTGT GCTTTGGCCA GTGCTGGGTG TTTGCTGGGA TCCTGACTAC AGTGCTGAGA 
GCGTTGGGCA TCCCAGCACG CAGTGTGACA GGCTTCGATT CAGCTCACGA CACAGAAAGG 
AACCTCACGG TGGACACCTA TGTGAATGAG AATGGCGAGA AAATCACCAG TATGACCCAC 
GACTCTGTCT GGAATTTCCA TGTGTGGACG GATGCCTGGA TGAAGCGACC GGATCTGCCC 
AAGGGCTACG ACGGCTGGCA GGCTGTGGAC GCAACGCCGC AGGAGCGAAG CCAGGGTGTC 
TTCTGCTGTG GGCCATCACC ACTGACCGCC ATCCGCAAAG GTGACATCTT TATTGTCTAT 
GACACCAGAT TCGTCTTCTC AGAAGTGAAT GGTGACAGGC TCATCTGGTT GGTGAAGATG 
GTGAATGGGC AGGAGGAGTT ACACGTAATT TCAATGGAGA CCACAAGCAT CGGGAAAAAC 
ATCAGCACCA AGGCAGTGGG CCAAGACAGG CGGAGAGATA TCACCTATGA GTACAAGTAT 
CCAGAAGGCT CCTCTGAGGA GAGGCAGGTC ATGGATCATG CCTTCCTCCT TCTCAGTTCT 
GAGAGGGAGC ACAGACGACC TGTAAAAGAG AACTTTCTTC ACATGTCGGT ACAATCAGAT 
GATGTGCTGC TGGGAAACTC TGTTAATTTC ACCGTGATTC TTAAAAGGAA GACCGCTGCC 
CTACAGAATG TCAACATCTT GGGCTCCTTT GAACTACAGT TGTACACTGG CAAGAAGATG 
GCAAAACTGT GTGACCTCAA TAAGACCTCG CAGATCCAAG GTCAAGTATC AGAAGTGACT 
CTGACCTTGG ACTCCAAGAC CTACATCAAC AGCCTGGCTA TATTAGATGA TGAGCCAGTT 
ATCAGAGGTT TCATCATTGC GGAAATTGTG GAGTCTAAGG AAATCATGGC CTCTGAAGTA 
TTCACGTCTT TCCAGTACCC TGAGTTCTCT ATAGAGTTGC CTAACACAGG CAGAATTGGC 
CAGCTACTTG TCTGCAATTG TATCTTCAAG AATACCCTGG CCATCCCTTT GACTGACGTC 
AAGTTCTCTT TGGAAAGCCT GGGCATCTCC TCACTACAGA CCTCTGACCA TGGGACGGTG 
CAGCCTGGTG AGACCATCCA ATCCCAAATA AAATGCACCC CAATAAAAAC TGGACCCAAG 
AAATTTATCG TCAAGTTAAG TTCCAAACAA GTGAAAGAGA TTAATGCTCA GAAGATTGTT 
CTCATCACCA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM4 ( NM_003241.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003232.2 Homo sapiens transglutaminase 4 (TGM4), mRNA.

Price & Availability↑

CloneID	OHu30658
Clone ID Related Accession (Same CDS sequence)	NM_003241.3 , NM_003241.4
Accession Version	NM_003241.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA870110.1, L34840.1, BF678064.1 and BC007003.1. On Aug 31, 2007 this sequence version replaced NM_003241.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC007003.1, U31905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146411, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END##

ATGATGGATG CATCAAAAGA GCTGCAAGTT CTCCACATTG ACTTCTTGAA TCAGGACAAC 
GCCGTTTCTC ACCACACATG GGAGTTCCAA ACGAGCAGTC CTGTGTTCCG GCGAGGACAG 
GTGTTTCACC TGCGGCTGGT GCTGAACCAG CCCCTACAAT CCTACCACCA ACTGAAACTG 
GAATTCAGCA CAGGGCCGAA TCCTAGCATC GCCAAACACA CCCTGGTGGT GCTCGACCCG 
AGGACGCCCT CAGACCACTA CAACTGGCAG GCAACCCTTC AAAATGAGTC TGGCAAAGAG 
GTCACAGTGG CTGTCACCAG TTCCCCCAAT GCCATCCTGG GCAAGTACCA ACTAAACGTG 
AAAACTGGAA ACCACATCCT TAAGTCTGAA GAAAACATCC TATACCTTCT CTTCAACCCA 
TGGTGTAAAG AGGACATGGT TTTCATGCCT GATGAGGACG AGCGCAAAGA GTACATCCTC 
AATGACACGG GCTGCCATTA CGTGGGGGCT GCCAGAAGTA TCAAATGCAA ACCCTGGAAC 
TTTGGTCAGT TTGAGAAAAA TGTCCTGGAC TGCTGCATTT CCCTGCTGAC TGAGAGCTCC 
CTCAAGCCCA CAGATAGGAG GGACCCCGTG CTGGTGTGCA GGGCCATGTG TGCTATGATG 
AGCTTTGAGA AAGGCCAGGG CGTGCTCATT GGGAATTGGA CTGGGGACTA CGAAGGTGGC 
ACAGCCCCAT ACAAGTGGAC AGGCAGTGCC CCGATCCTGC AGCAGTACTA CAACACGAAG 
CAGGCTGTGT GCTTTGGCCA GTGCTGGGTG TTTGCTGGGA TCCTGACTAC AGTGCTGAGA 
GCGTTGGGCA TCCCAGCACG CAGTGTGACA GGCTTCGATT CAGCTCACGA CACAGAAAGG 
AACCTCACGG TGGACACCTA TGTGAATGAG AATGGCGAGA AAATCACCAG TATGACCCAC 
GACTCTGTCT GGAATTTCCA TGTGTGGACG GATGCCTGGA TGAAGCGACC GGATCTGCCC 
AAGGGCTACG ACGGCTGGCA GGCTGTGGAC GCAACGCCGC AGGAGCGAAG CCAGGGTGTC 
TTCTGCTGTG GGCCATCACC ACTGACCGCC ATCCGCAAAG GTGACATCTT TATTGTCTAT 
GACACCAGAT TCGTCTTCTC AGAAGTGAAT GGTGACAGGC TCATCTGGTT GGTGAAGATG 
GTGAATGGGC AGGAGGAGTT ACACGTAATT TCAATGGAGA CCACAAGCAT CGGGAAAAAC 
ATCAGCACCA AGGCAGTGGG CCAAGACAGG CGGAGAGATA TCACCTATGA GTACAAGTAT 
CCAGAAGGCT CCTCTGAGGA GAGGCAGGTC ATGGATCATG CCTTCCTCCT TCTCAGTTCT 
GAGAGGGAGC ACAGACGACC TGTAAAAGAG AACTTTCTTC ACATGTCGGT ACAATCAGAT 
GATGTGCTGC TGGGAAACTC TGTTAATTTC ACCGTGATTC TTAAAAGGAA GACCGCTGCC 
CTACAGAATG TCAACATCTT GGGCTCCTTT GAACTACAGT TGTACACTGG CAAGAAGATG 
GCAAAACTGT GTGACCTCAA TAAGACCTCG CAGATCCAAG GTCAAGTATC AGAAGTGACT 
CTGACCTTGG ACTCCAAGAC CTACATCAAC AGCCTGGCTA TATTAGATGA TGAGCCAGTT 
ATCAGAGGTT TCATCATTGC GGAAATTGTG GAGTCTAAGG AAATCATGGC CTCTGAAGTA 
TTCACGTCTT TCCAGTACCC TGAGTTCTCT ATAGAGTTGC CTAACACAGG CAGAATTGGC 
CAGCTACTTG TCTGCAATTG TATCTTCAAG AATACCCTGG CCATCCCTTT GACTGACGTC 
AAGTTCTCTT TGGAAAGCCT GGGCATCTCC TCACTACAGA CCTCTGACCA TGGGACGGTG 
CAGCCTGGTG AGACCATCCA ATCCCAAATA AAATGCACCC CAATAAAAAC TGGACCCAAG 
AAATTTATCG TCAAGTTAAG TTCCAAACAA GTGAAAGAGA TTAATGCTCA GAAGATTGTT 
CTCATCACCA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003232.2
CDS	74..2128
Translation	MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK

Target ORF information:

RefSeq Version	NM_003241.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 4 (TGM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003241.3

ORF Insert Sequence:

ATGATGGATG CATCAAAAGA GCTGCAAGTT CTCCACATTG ACTTCTTGAA TCAGGACAAC 
GCCGTTTCTC ACCACACATG GGAGTTCCAA ACGAGCAGTC CTGTGTTCCG GCGAGGACAG 
GTGTTTCACC TGCGGCTGGT GCTGAACCAG CCCCTACAAT CCTACCACCA ACTGAAACTG 
GAATTCAGCA CAGGGCCGAA TCCTAGCATC GCCAAACACA CCCTGGTGGT GCTCGACCCG 
AGGACGCCCT CAGACCACTA CAACTGGCAG GCAACCCTTC AAAATGAGTC TGGCAAAGAG 
GTCACAGTGG CTGTCACCAG TTCCCCCAAT GCCATCCTGG GCAAGTACCA ACTAAACGTG 
AAAACTGGAA ACCACATCCT TAAGTCTGAA GAAAACATCC TATACCTTCT CTTCAACCCA 
TGGTGTAAAG AGGACATGGT TTTCATGCCT GATGAGGACG AGCGCAAAGA GTACATCCTC 
AATGACACGG GCTGCCATTA CGTGGGGGCT GCCAGAAGTA TCAAATGCAA ACCCTGGAAC 
TTTGGTCAGT TTGAGAAAAA TGTCCTGGAC TGCTGCATTT CCCTGCTGAC TGAGAGCTCC 
CTCAAGCCCA CAGATAGGAG GGACCCCGTG CTGGTGTGCA GGGCCATGTG TGCTATGATG 
AGCTTTGAGA AAGGCCAGGG CGTGCTCATT GGGAATTGGA CTGGGGACTA CGAAGGTGGC 
ACAGCCCCAT ACAAGTGGAC AGGCAGTGCC CCGATCCTGC AGCAGTACTA CAACACGAAG 
CAGGCTGTGT GCTTTGGCCA GTGCTGGGTG TTTGCTGGGA TCCTGACTAC AGTGCTGAGA 
GCGTTGGGCA TCCCAGCACG CAGTGTGACA GGCTTCGATT CAGCTCACGA CACAGAAAGG 
AACCTCACGG TGGACACCTA TGTGAATGAG AATGGCGAGA AAATCACCAG TATGACCCAC 
GACTCTGTCT GGAATTTCCA TGTGTGGACG GATGCCTGGA TGAAGCGACC GGATCTGCCC 
AAGGGCTACG ACGGCTGGCA GGCTGTGGAC GCAACGCCGC AGGAGCGAAG CCAGGGTGTC 
TTCTGCTGTG GGCCATCACC ACTGACCGCC ATCCGCAAAG GTGACATCTT TATTGTCTAT 
GACACCAGAT TCGTCTTCTC AGAAGTGAAT GGTGACAGGC TCATCTGGTT GGTGAAGATG 
GTGAATGGGC AGGAGGAGTT ACACGTAATT TCAATGGAGA CCACAAGCAT CGGGAAAAAC 
ATCAGCACCA AGGCAGTGGG CCAAGACAGG CGGAGAGATA TCACCTATGA GTACAAGTAT 
CCAGAAGGCT CCTCTGAGGA GAGGCAGGTC ATGGATCATG CCTTCCTCCT TCTCAGTTCT 
GAGAGGGAGC ACAGACGACC TGTAAAAGAG AACTTTCTTC ACATGTCGGT ACAATCAGAT 
GATGTGCTGC TGGGAAACTC TGTTAATTTC ACCGTGATTC TTAAAAGGAA GACCGCTGCC 
CTACAGAATG TCAACATCTT GGGCTCCTTT GAACTACAGT TGTACACTGG CAAGAAGATG 
GCAAAACTGT GTGACCTCAA TAAGACCTCG CAGATCCAAG GTCAAGTATC AGAAGTGACT 
CTGACCTTGG ACTCCAAGAC CTACATCAAC AGCCTGGCTA TATTAGATGA TGAGCCAGTT 
ATCAGAGGTT TCATCATTGC GGAAATTGTG GAGTCTAAGG AAATCATGGC CTCTGAAGTA 
TTCACGTCTT TCCAGTACCC TGAGTTCTCT ATAGAGTTGC CTAACACAGG CAGAATTGGC 
CAGCTACTTG TCTGCAATTG TATCTTCAAG AATACCCTGG CCATCCCTTT GACTGACGTC 
AAGTTCTCTT TGGAAAGCCT GGGCATCTCC TCACTACAGA CCTCTGACCA TGGGACGGTG 
CAGCCTGGTG AGACCATCCA ATCCCAAATA AAATGCACCC CAATAAAAAC TGGACCCAAG 
AAATTTATCG TCAAGTTAAG TTCCAAACAA GTGAAAGAGA TTAATGCTCA GAAGATTGTT 
CTCATCACCA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM4 ( XM_011534042.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532344.1 Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu60977
Clone ID Related Accession (Same CDS sequence)	XM_011534042.1 , XM_011534042.2
Accession Version	XM_011534042.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGATG CATCAAAAGA GTTGAGGTCT CACTTTGTTG CCCAGGCTGG CGTGTTGTGG 
CTATTCACAG CTGCAATCAT AGCTCACTGC AGCCTCAAAC TCCTGGGCTC AAGTGATTCT 
CCCACCTCAG TCTCCCGAGT AACCGGGATT ACAGAGCTGC AAGTTCTCCA CATTGACTTC 
TTGAATCAGG ACAACGCCGT TTCTCACCAC ACATGGGAGT TCCAAACGAG CAGTCCTGTG 
TTCCGGCGAG GACAGGTGTT TCACCTGCGG CTGGTGCTGA ACCAGCCCCT ACAATCCTAC 
CACCAACTGA AACTGGAATT CAGCACAGGG CCGAATCCTA GCATCGCCAA ACACACCCTG 
GTGGTGCTCG ACCCGAGGAC GCCCTCAGAC CACTACAACT GGCAGGCAAC CCTTCAAAAT 
GAGTCTGGCA AAGAGGTCAC AGTGGCTGTC ACCAGTTCCC CCAATGCCAT CCTGGGCAAG 
TACCAACTAA ACGTGAAAAC TGGAAACCAC ATCCTTAAGT CTGAAGAAAA CATCCTATAC 
CTTCTCTTCA ACCCATGGTG TAAAGAGGAC ATGGTTTTCA TGCCTGATGA GGACGAGCGC 
AAAGAGTACA TCCTCAATGA CACGGGCTGC CATTACGTGG GGGCTGCCAG AAGTATCAAA 
TGCAAACCCT GGAACTTTGG TCAGTTTGAG AAAAATGTCC TGGACTGCTG CATTTCCCTG 
CTGACTGAGA GCTCCCTCAA GCCCACAGAT AGGAGGGACC CCGTGCTGGT GTGCAGGGCC 
ATGTGTGCTA TGATGAGCTT TGAGAAAGGC CAGGGCGTGC TCATTGGGAA TTGGACTGGG 
GACTACGAAG GTGGCACAGC CCCATACAAG TGGACAGGCA GTGCCCCGAT CCTGCAGCAG 
TACTACAACA CGAAGCAGGC TGTGTGCTTT GGCCAGTGCT GGGTGTTTGC TGGGATCCTG 
ACTACAGTGC TGAGAGCGTT GGGCATCCCA GCACGCAGTG TGACAGGCTT CGATTCAGCT 
CACGACACAG AAAGGAACCT CACGGTGGAC ACCTATGTGA ATGAGAATGG CGAGAAAATC 
ACCAGTATGA CCCACGACTC TGTCTGGAAT TTCCATGTGT GGACGGATGC CTGGATGAAG 
CGACCGGATC TGCCCAAGGG CTACGACGGC TGGCAGGCTG TGGACGCAAC GCCGCAGGAG 
CGAAGCCAGG GTGTCTTCTG CTGTGGGCCA TCACCACTGA CCGCCATCCG CAAAGGTGAC 
ATCTTTATTG TCTATGACAC CAGATTCGTC TTCTCAGAAG TGAATGGTGA CAGGCTCATC 
TGGTTGGTGA AGATGGTGAA TGGGCAGGAG GAGTTACACG TAATTTCAAT GGAGACCACA 
AGCATCGGGA AAAACATCAG CACCAAGGCA GTGGGCCAAG ACAGGCGGAG AGATATCACC 
TATGAGTACA AGTATCCAGA AGGCTCCTCT GAGGAGAGGC AGGTCATGGA TCATGCCTTC 
CTCCTTCTCA GTTCTGAGAG GGAGCACAGA CGACCTGTAA AAGAGAACTT TCTTCACATG 
TCGGTACAAT CAGATGATGT GCTGCTGGGA AACTCTGTTA ATTTCACCGT GATTCTTAAA 
AGGAAGACCG CTGCCCTACA GAATGTCAAC ATCTTGGGCT CCTTTGAACT ACAGTTGTAC 
ACTGGCAAGA AGATGGCAAA ACTGTGTGAC CTCAATAAGA CCTCGCAGAT CCAAGGTCAA 
GTATCAGAAG TGACTCTGAC CTTGGACTCC AAGACCTACA TCAACAGCCT GGCTATATTA 
GATGATGAGC CAGTTATCAG AGGTTTCATC ATTGCGGAAA TTGTGGAGTC TAAGGAAATC 
ATGGCCTCTG AAGTATTCAC GTCTTTCCAG TACCCTGAGT TCTCTATAGA GTTGCCTAAC 
ACAGGCAGAA TTGGCCAGCT ACTTGTCTGC AATTGTATCT TCAAGAATAC CCTGGCCATC 
CCTTTGACTG ACGTCAAGTT CTCTTTGGAA AGCCTGGGCA TCTCCTCACT ACAGACCTCT 
GACCATGGGA CGGTGCAGCC TGGTGAGACC ATCCAATCCC AAATAAAATG CACCCCAATA 
AAAACTGGAC CCAAGAAATT TATCGTCAAG TTAAGTTCCA AACAAGTGAA AGAGATTAAT 
GCTCAGAAGA TTGTTCTCAT CACCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532344.1
CDS	88..2277
Translation	MMDASKELRSHFVAQAGVLWLFTAAIIAHCSLKLLGSSDSPTSVSRVTGITELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK

Target ORF information:

RefSeq Version	XM_011534042.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534042.1

ORF Insert Sequence:

ATGATGGATG CATCAAAAGA GTTGAGGTCT CACTTTGTTG CCCAGGCTGG CGTGTTGTGG 
CTATTCACAG CTGCAATCAT AGCTCACTGC AGCCTCAAAC TCCTGGGCTC AAGTGATTCT 
CCCACCTCAG TCTCCCGAGT AACCGGGATT ACAGAGCTGC AAGTTCTCCA CATTGACTTC 
TTGAATCAGG ACAACGCCGT TTCTCACCAC ACATGGGAGT TCCAAACGAG CAGTCCTGTG 
TTCCGGCGAG GACAGGTGTT TCACCTGCGG CTGGTGCTGA ACCAGCCCCT ACAATCCTAC 
CACCAACTGA AACTGGAATT CAGCACAGGG CCGAATCCTA GCATCGCCAA ACACACCCTG 
GTGGTGCTCG ACCCGAGGAC GCCCTCAGAC CACTACAACT GGCAGGCAAC CCTTCAAAAT 
GAGTCTGGCA AAGAGGTCAC AGTGGCTGTC ACCAGTTCCC CCAATGCCAT CCTGGGCAAG 
TACCAACTAA ACGTGAAAAC TGGAAACCAC ATCCTTAAGT CTGAAGAAAA CATCCTATAC 
CTTCTCTTCA ACCCATGGTG TAAAGAGGAC ATGGTTTTCA TGCCTGATGA GGACGAGCGC 
AAAGAGTACA TCCTCAATGA CACGGGCTGC CATTACGTGG GGGCTGCCAG AAGTATCAAA 
TGCAAACCCT GGAACTTTGG TCAGTTTGAG AAAAATGTCC TGGACTGCTG CATTTCCCTG 
CTGACTGAGA GCTCCCTCAA GCCCACAGAT AGGAGGGACC CCGTGCTGGT GTGCAGGGCC 
ATGTGTGCTA TGATGAGCTT TGAGAAAGGC CAGGGCGTGC TCATTGGGAA TTGGACTGGG 
GACTACGAAG GTGGCACAGC CCCATACAAG TGGACAGGCA GTGCCCCGAT CCTGCAGCAG 
TACTACAACA CGAAGCAGGC TGTGTGCTTT GGCCAGTGCT GGGTGTTTGC TGGGATCCTG 
ACTACAGTGC TGAGAGCGTT GGGCATCCCA GCACGCAGTG TGACAGGCTT CGATTCAGCT 
CACGACACAG AAAGGAACCT CACGGTGGAC ACCTATGTGA ATGAGAATGG CGAGAAAATC 
ACCAGTATGA CCCACGACTC TGTCTGGAAT TTCCATGTGT GGACGGATGC CTGGATGAAG 
CGACCGGATC TGCCCAAGGG CTACGACGGC TGGCAGGCTG TGGACGCAAC GCCGCAGGAG 
CGAAGCCAGG GTGTCTTCTG CTGTGGGCCA TCACCACTGA CCGCCATCCG CAAAGGTGAC 
ATCTTTATTG TCTATGACAC CAGATTCGTC TTCTCAGAAG TGAATGGTGA CAGGCTCATC 
TGGTTGGTGA AGATGGTGAA TGGGCAGGAG GAGTTACACG TAATTTCAAT GGAGACCACA 
AGCATCGGGA AAAACATCAG CACCAAGGCA GTGGGCCAAG ACAGGCGGAG AGATATCACC 
TATGAGTACA AGTATCCAGA AGGCTCCTCT GAGGAGAGGC AGGTCATGGA TCATGCCTTC 
CTCCTTCTCA GTTCTGAGAG GGAGCACAGA CGACCTGTAA AAGAGAACTT TCTTCACATG 
TCGGTACAAT CAGATGATGT GCTGCTGGGA AACTCTGTTA ATTTCACCGT GATTCTTAAA 
AGGAAGACCG CTGCCCTACA GAATGTCAAC ATCTTGGGCT CCTTTGAACT ACAGTTGTAC 
ACTGGCAAGA AGATGGCAAA ACTGTGTGAC CTCAATAAGA CCTCGCAGAT CCAAGGTCAA 
GTATCAGAAG TGACTCTGAC CTTGGACTCC AAGACCTACA TCAACAGCCT GGCTATATTA 
GATGATGAGC CAGTTATCAG AGGTTTCATC ATTGCGGAAA TTGTGGAGTC TAAGGAAATC 
ATGGCCTCTG AAGTATTCAC GTCTTTCCAG TACCCTGAGT TCTCTATAGA GTTGCCTAAC 
ACAGGCAGAA TTGGCCAGCT ACTTGTCTGC AATTGTATCT TCAAGAATAC CCTGGCCATC 
CCTTTGACTG ACGTCAAGTT CTCTTTGGAA AGCCTGGGCA TCTCCTCACT ACAGACCTCT 
GACCATGGGA CGGTGCAGCC TGGTGAGACC ATCCAATCCC AAATAAAATG CACCCCAATA 
AAAACTGGAC CCAAGAAATT TATCGTCAAG TTAAGTTCCA AACAAGTGAA AGAGATTAAT 
GCTCAGAAGA TTGTTCTCAT CACCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TGM4 ( XM_011534042.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532344.1 Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu60977
Clone ID Related Accession (Same CDS sequence)	XM_011534042.1 , XM_011534042.2
Accession Version	XM_011534042.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein-glutamine gamma-glutamyltransferase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011534042.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGATG CATCAAAAGA GTTGAGGTCT CACTTTGTTG CCCAGGCTGG CGTGTTGTGG 
CTATTCACAG CTGCAATCAT AGCTCACTGC AGCCTCAAAC TCCTGGGCTC AAGTGATTCT 
CCCACCTCAG TCTCCCGAGT AACCGGGATT ACAGAGCTGC AAGTTCTCCA CATTGACTTC 
TTGAATCAGG ACAACGCCGT TTCTCACCAC ACATGGGAGT TCCAAACGAG CAGTCCTGTG 
TTCCGGCGAG GACAGGTGTT TCACCTGCGG CTGGTGCTGA ACCAGCCCCT ACAATCCTAC 
CACCAACTGA AACTGGAATT CAGCACAGGG CCGAATCCTA GCATCGCCAA ACACACCCTG 
GTGGTGCTCG ACCCGAGGAC GCCCTCAGAC CACTACAACT GGCAGGCAAC CCTTCAAAAT 
GAGTCTGGCA AAGAGGTCAC AGTGGCTGTC ACCAGTTCCC CCAATGCCAT CCTGGGCAAG 
TACCAACTAA ACGTGAAAAC TGGAAACCAC ATCCTTAAGT CTGAAGAAAA CATCCTATAC 
CTTCTCTTCA ACCCATGGTG TAAAGAGGAC ATGGTTTTCA TGCCTGATGA GGACGAGCGC 
AAAGAGTACA TCCTCAATGA CACGGGCTGC CATTACGTGG GGGCTGCCAG AAGTATCAAA 
TGCAAACCCT GGAACTTTGG TCAGTTTGAG AAAAATGTCC TGGACTGCTG CATTTCCCTG 
CTGACTGAGA GCTCCCTCAA GCCCACAGAT AGGAGGGACC CCGTGCTGGT GTGCAGGGCC 
ATGTGTGCTA TGATGAGCTT TGAGAAAGGC CAGGGCGTGC TCATTGGGAA TTGGACTGGG 
GACTACGAAG GTGGCACAGC CCCATACAAG TGGACAGGCA GTGCCCCGAT CCTGCAGCAG 
TACTACAACA CGAAGCAGGC TGTGTGCTTT GGCCAGTGCT GGGTGTTTGC TGGGATCCTG 
ACTACAGTGC TGAGAGCGTT GGGCATCCCA GCACGCAGTG TGACAGGCTT CGATTCAGCT 
CACGACACAG AAAGGAACCT CACGGTGGAC ACCTATGTGA ATGAGAATGG CGAGAAAATC 
ACCAGTATGA CCCACGACTC TGTCTGGAAT TTCCATGTGT GGACGGATGC CTGGATGAAG 
CGACCGGATC TGCCCAAGGG CTACGACGGC TGGCAGGCTG TGGACGCAAC GCCGCAGGAG 
CGAAGCCAGG GTGTCTTCTG CTGTGGGCCA TCACCACTGA CCGCCATCCG CAAAGGTGAC 
ATCTTTATTG TCTATGACAC CAGATTCGTC TTCTCAGAAG TGAATGGTGA CAGGCTCATC 
TGGTTGGTGA AGATGGTGAA TGGGCAGGAG GAGTTACACG TAATTTCAAT GGAGACCACA 
AGCATCGGGA AAAACATCAG CACCAAGGCA GTGGGCCAAG ACAGGCGGAG AGATATCACC 
TATGAGTACA AGTATCCAGA AGGCTCCTCT GAGGAGAGGC AGGTCATGGA TCATGCCTTC 
CTCCTTCTCA GTTCTGAGAG GGAGCACAGA CGACCTGTAA AAGAGAACTT TCTTCACATG 
TCGGTACAAT CAGATGATGT GCTGCTGGGA AACTCTGTTA ATTTCACCGT GATTCTTAAA 
AGGAAGACCG CTGCCCTACA GAATGTCAAC ATCTTGGGCT CCTTTGAACT ACAGTTGTAC 
ACTGGCAAGA AGATGGCAAA ACTGTGTGAC CTCAATAAGA CCTCGCAGAT CCAAGGTCAA 
GTATCAGAAG TGACTCTGAC CTTGGACTCC AAGACCTACA TCAACAGCCT GGCTATATTA 
GATGATGAGC CAGTTATCAG AGGTTTCATC ATTGCGGAAA TTGTGGAGTC TAAGGAAATC 
ATGGCCTCTG AAGTATTCAC GTCTTTCCAG TACCCTGAGT TCTCTATAGA GTTGCCTAAC 
ACAGGCAGAA TTGGCCAGCT ACTTGTCTGC AATTGTATCT TCAAGAATAC CCTGGCCATC 
CCTTTGACTG ACGTCAAGTT CTCTTTGGAA AGCCTGGGCA TCTCCTCACT ACAGACCTCT 
GACCATGGGA CGGTGCAGCC TGGTGAGACC ATCCAATCCC AAATAAAATG CACCCCAATA 
AAAACTGGAC CCAAGAAATT TATCGTCAAG TTAAGTTCCA AACAAGTGAA AGAGATTAAT 
GCTCAGAAGA TTGTTCTCAT CACCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532344.1
CDS	72..2261
Translation	MMDASKELRSHFVAQAGVLWLFTAAIIAHCSLKLLGSSDSPTSVSRVTGITELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK

Target ORF information:

RefSeq Version	XM_011534042.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transglutaminase 4 (TGM4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534042.2

ORF Insert Sequence:

ATGATGGATG CATCAAAAGA GTTGAGGTCT CACTTTGTTG CCCAGGCTGG CGTGTTGTGG 
CTATTCACAG CTGCAATCAT AGCTCACTGC AGCCTCAAAC TCCTGGGCTC AAGTGATTCT 
CCCACCTCAG TCTCCCGAGT AACCGGGATT ACAGAGCTGC AAGTTCTCCA CATTGACTTC 
TTGAATCAGG ACAACGCCGT TTCTCACCAC ACATGGGAGT TCCAAACGAG CAGTCCTGTG 
TTCCGGCGAG GACAGGTGTT TCACCTGCGG CTGGTGCTGA ACCAGCCCCT ACAATCCTAC 
CACCAACTGA AACTGGAATT CAGCACAGGG CCGAATCCTA GCATCGCCAA ACACACCCTG 
GTGGTGCTCG ACCCGAGGAC GCCCTCAGAC CACTACAACT GGCAGGCAAC CCTTCAAAAT 
GAGTCTGGCA AAGAGGTCAC AGTGGCTGTC ACCAGTTCCC CCAATGCCAT CCTGGGCAAG 
TACCAACTAA ACGTGAAAAC TGGAAACCAC ATCCTTAAGT CTGAAGAAAA CATCCTATAC 
CTTCTCTTCA ACCCATGGTG TAAAGAGGAC ATGGTTTTCA TGCCTGATGA GGACGAGCGC 
AAAGAGTACA TCCTCAATGA CACGGGCTGC CATTACGTGG GGGCTGCCAG AAGTATCAAA 
TGCAAACCCT GGAACTTTGG TCAGTTTGAG AAAAATGTCC TGGACTGCTG CATTTCCCTG 
CTGACTGAGA GCTCCCTCAA GCCCACAGAT AGGAGGGACC CCGTGCTGGT GTGCAGGGCC 
ATGTGTGCTA TGATGAGCTT TGAGAAAGGC CAGGGCGTGC TCATTGGGAA TTGGACTGGG 
GACTACGAAG GTGGCACAGC CCCATACAAG TGGACAGGCA GTGCCCCGAT CCTGCAGCAG 
TACTACAACA CGAAGCAGGC TGTGTGCTTT GGCCAGTGCT GGGTGTTTGC TGGGATCCTG 
ACTACAGTGC TGAGAGCGTT GGGCATCCCA GCACGCAGTG TGACAGGCTT CGATTCAGCT 
CACGACACAG AAAGGAACCT CACGGTGGAC ACCTATGTGA ATGAGAATGG CGAGAAAATC 
ACCAGTATGA CCCACGACTC TGTCTGGAAT TTCCATGTGT GGACGGATGC CTGGATGAAG 
CGACCGGATC TGCCCAAGGG CTACGACGGC TGGCAGGCTG TGGACGCAAC GCCGCAGGAG 
CGAAGCCAGG GTGTCTTCTG CTGTGGGCCA TCACCACTGA CCGCCATCCG CAAAGGTGAC 
ATCTTTATTG TCTATGACAC CAGATTCGTC TTCTCAGAAG TGAATGGTGA CAGGCTCATC 
TGGTTGGTGA AGATGGTGAA TGGGCAGGAG GAGTTACACG TAATTTCAAT GGAGACCACA 
AGCATCGGGA AAAACATCAG CACCAAGGCA GTGGGCCAAG ACAGGCGGAG AGATATCACC 
TATGAGTACA AGTATCCAGA AGGCTCCTCT GAGGAGAGGC AGGTCATGGA TCATGCCTTC 
CTCCTTCTCA GTTCTGAGAG GGAGCACAGA CGACCTGTAA AAGAGAACTT TCTTCACATG 
TCGGTACAAT CAGATGATGT GCTGCTGGGA AACTCTGTTA ATTTCACCGT GATTCTTAAA 
AGGAAGACCG CTGCCCTACA GAATGTCAAC ATCTTGGGCT CCTTTGAACT ACAGTTGTAC 
ACTGGCAAGA AGATGGCAAA ACTGTGTGAC CTCAATAAGA CCTCGCAGAT CCAAGGTCAA 
GTATCAGAAG TGACTCTGAC CTTGGACTCC AAGACCTACA TCAACAGCCT GGCTATATTA 
GATGATGAGC CAGTTATCAG AGGTTTCATC ATTGCGGAAA TTGTGGAGTC TAAGGAAATC 
ATGGCCTCTG AAGTATTCAC GTCTTTCCAG TACCCTGAGT TCTCTATAGA GTTGCCTAAC 
ACAGGCAGAA TTGGCCAGCT ACTTGTCTGC AATTGTATCT TCAAGAATAC CCTGGCCATC 
CCTTTGACTG ACGTCAAGTT CTCTTTGGAA AGCCTGGGCA TCTCCTCACT ACAGACCTCT 
GACCATGGGA CGGTGCAGCC TGGTGAGACC ATCCAATCCC AAATAAAATG CACCCCAATA 
AAAACTGGAC CCAAGAAATT TATCGTCAAG TTAAGTTCCA AACAAGTGAA AGAGATTAAT 
GCTCAGAAGA TTGTTCTCAT CACCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transglutaminase 4 as a prostate autoantigen in male subfertility.
Science translational medicine7(292)292ra101(2015 Jun)
Landegren N,Sharon D,Shum AK,Khan IS,Fasano KJ,Hallgren ?,Kampf C,Freyhult E,Ardesj?-Lundgren B,Alimohammadi M,Rathsman S,Ludvigsson JF,Lundh D,Motrich R,Rivero V,Fong L,Giwercman A,Gustafsson J,Perheentupa J,Husebye ES,Anderson MS,Snyder M,K?mpe O

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Nature communications54020(2014 Jun)
Navarini AA,Simpson MA,Weale M,Knight J,Carlavan I,Reiniche P,Burden DA,Layton A,Bataille V,Allen M,Pleass R,Pink A,Creamer D,English J,Munn S,Walton S,,Willis C,D?ret S,Voegel JJ,Spector T,Smith CH,Trembath RC,Barker JN

Overexpression of transglutaminase 4 and prostate cancer progression: a potential predictor of less favourable outcomes.
Asian journal of andrology15(6)742-6(2013 Nov)
Cao Z,Wang Y,Liu ZY,Zhang ZS,Ren SC,Yu YW,Qiao M,Zhai BB,Sun YH

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance.
Nucleic acids research40(11)4825-40(2012 Jun)
Rivera-Gonzalez GC,Droop AP,Rippon HJ,Tiemann K,Pellacani D,Georgopoulos LJ,Maitland NJ

Analysis of laser-microdissected prostate cancer tissues reveals potential tumor markers.
International journal of molecular medicine28(4)605-11(2011 Oct)
Shaikhibrahim Z,Lindstrot A,Buettner R,Wernert N

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TGM4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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