TFR2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TFR2
Entrez Gene ID	7036
Full Name	transferrin receptor 2
Synonyms	HFE3,TFRC2
General protein information	Preferred Names transferrin receptor 2 Names transferrin receptor protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q22.1
Summary	This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
Disorder MIM:	604720
Disorder Html:	Hemochromatosis, type 3, 604250 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005250553.4	XP_005250610.1	transferrin receptor protein 2 isoform X1
NM_001206855.2	NP_001193784.1	transferrin receptor protein 2 isoform 2
XM_017012573.1	XP_016868062.1	transferrin receptor protein 2 isoform X1
XM_005250553.3	XP_005250610.1	transferrin receptor protein 2 isoform X1
NM_001206855.1	NP_001193784.1	transferrin receptor protein 2 isoform 2
NM_003227.3	NP_003218.2	transferrin receptor protein 2 isoform 1
NM_003227.4	NP_003218.2	transferrin receptor protein 2 isoform 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TFR2	NP_001171212.1
Rattus norvegicus (Norway rat)	Tfr2	NP_001099386.1
Mus musculus (house mouse)	Tfr2	NP_056614.3
Homo sapiens (human)	TFR2	NP_003218.2
Pan troglodytes (chimpanzee)	TFR2	XP_003318698.1
	TFR2	XP_001113151.1
Canis lupus familiaris (dog)	TFR2	XP_005621095.1
Danio rerio (zebrafish)	tfr2	NP_001009916.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical significance of TFR2 and EPOR expression in bone marrow cells in myelodysplastic syndromes.
Di Savino A, Gaidano V, Palmieri A, Crasto F, Volpengo A, Lorenzatti R, Scaravaglio P, Manello A, Nicoli P, Gottardi E, Saglio G, Cilloni D, De Gobbi M
British journal of haematology176(3)491-495(2017 Feb)

Next-generation sequencing of hereditary hemochromatosis-related genes: Novel likely pathogenic variants found in the Portuguese population.
Faria R, Silva B, Silva C, Loureiro P, Queiroz A, Fraga S, Esteves J, Mendes D, Fleming R, Vieira L, Gon?alves J, Faustino P
Blood cells, molecules & diseases6110-5(2016 Oct)

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells.
Mehta K, Busbridge M, Renshaw D, Evans RW, Farnaud S, Patel VB
Blood cells, molecules & diseases6137-45(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

unreported iron metabolism-related genes in non-classic hereditary hemochromatosis patients that were predicted to be potentially pathogenic were three novel mutations in TFR2 [two missense (p.Leu750Pro and p.Ala777Val) and one intronic splicing mutation (c.967-1G>C)], one missense mutation in HFE (p.Tyr230Cys), and one mutation in the 5'-UTR of HAMP gene (c.-25G>A)
Title: Next-generation sequencing of hereditary hemochromatosis-related genes: Novel likely pathogenic variants found in the Portuguese population.

TFR2 expression altered within 4h of HAMP treatment, while HFE expression altered later at 24h and 48h, suggesting that TFR2 may function prior to HFE in HAMP regulation.
Title: Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells.

Transferrin facilitates the formation of DNA double-strand breaks (DNA-DSBs) via transferrin receptor TfR1 but not TfR2.
Title: Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer.

Of the non-HFE forms of iron overload, TFR2-, HFE2-, and HAMP-related forms are predicted to be rare, with pathogenic allele frequencies in the range of 0.00007 to 0.0005. Significantly, SLC40A1 variants that have been previously associated with autosomal-dominant ferroportin disease were identified in several populations (pathogenic allele frequency 0.0004), being most prevalent among Africans
Title: The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing data.

Our results indicate that membrane transferrin receptor-2, a sensor of circulating iron, is released from the cell membrane in iron deficiency.
Title: Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.

The following TFR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TFR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18638	NM_003227.4 Latest version!	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18638	XM_017012573.1 Latest version!	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18638	XM_005250553.4 Latest version!	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu16938	NM_001206855.1 Latest version!	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu106955	NM_001206855.2 Latest version!	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu18638	XM_005250553.3	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18638	NM_003227.3	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TFR2 ( NM_003227.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003218.2 Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18638
Clone ID Related Accession (Same CDS sequence)	XM_005250553.4 , XM_017012573.1 , XM_005250553.3 , NM_003227.3 , NM_003227.4
Accession Version	NM_003227.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004213.1, AF067864.1 and BI917390.1. This sequence is a reference standard in the RefSeqGene project. On Jul 7, 2006 this sequence version replaced NM_003227.2. Transcript Variant: This variant (1) encodes the longer isoform (1, also known as alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF067864.1, BC142630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003218.2
CDS	42..2447
Translation	MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	NM_003227.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003227.3

ORF Insert Sequence:

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( NM_003227.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003218.2 Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18638
Clone ID Related Accession (Same CDS sequence)	XM_005250553.4 , XM_017012573.1 , XM_005250553.3 , NM_003227.3 , NM_003227.4
Accession Version	NM_003227.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC099394.6, DR004213.1, AF067864.1 and BI917390.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003227.3. Transcript Variant: This variant (1) encodes the longer isoform (1, also known as alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC142630.1, AF067864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000223051.8/ ENSP00000223051.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003218.2
CDS	44..2449
Translation	MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	NM_003227.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003227.4

ORF Insert Sequence:

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( XM_005250553.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250610.1 Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu18638
Clone ID Related Accession (Same CDS sequence)	XM_005250553.4 , XM_017012573.1 , XM_005250553.3 , NM_003227.3 , NM_003227.4
Accession Version	XM_005250553.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250553.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250610.1
CDS	348..2753
Translation	MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	XM_005250553.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250553.4

ORF Insert Sequence:

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( XM_017012573.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868062.1 Homo sapiens transferrin receptor 2 (TFR2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu18638
Clone ID Related Accession (Same CDS sequence)	XM_005250553.4 , XM_017012573.1 , XM_005250553.3 , NM_003227.3 , NM_003227.4
Accession Version	XM_017012573.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868062.1
CDS	150..2555
Translation	MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	XM_017012573.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012573.1

ORF Insert Sequence:

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( XM_005250553.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250610.1 Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu18638
Clone ID Related Accession (Same CDS sequence)	XM_005250553.4 , XM_017012573.1 , XM_005250553.3 , NM_003227.3 , NM_003227.4
Accession Version	XM_005250553.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	transferrin receptor protein 2 isoform X1
Comment

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005250610.1

Translation

MERLWGLFQRAQQLSPRSSQTVYQRVEGPRKGHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	XM_005250553.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250553.3

ORF Insert Sequence:

ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC 
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG 
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG 
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC 
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG 
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC 
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC 
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC 
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG 
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC 
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC 
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG 
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC 
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG 
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT 
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA 
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT 
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG 
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG 
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC 
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA 
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG 
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC 
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA 
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG 
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC 
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG 
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC 
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG 
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG 
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC 
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC 
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC 
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG 
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG 
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG 
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG 
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC 
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC 
TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( NM_001206855.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193784.1 Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16938
Clone ID Related Accession (Same CDS sequence)	NM_001206855.1
Accession Version	NM_001206855.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX384750.2 and AF067864.1. Transcript Variant: This variant (2) differs at the 5' end compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in an isoform (2, also known as beta) with a shorter N-terminus (lacking the transmembrane domain) compared to isoform 1. While there is transcript support for this variant (PMID:10409623), the protein is predicted. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2155590, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG 
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC 
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG 
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG 
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG 
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA 
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC 
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT 
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC 
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG 
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC 
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC 
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG 
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC 
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAA 
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG 
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT 
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG 
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC 
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC 
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG 
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC 
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC 
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG 
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG 
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG 
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC 
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG 
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT 
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC 
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193784.1
CDS	135..2027
Translation	MAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	NM_001206855.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206855.1

ORF Insert Sequence:

ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG 
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC 
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG 
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG 
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG 
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA 
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC 
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT 
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC 
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG 
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC 
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC 
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG 
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC 
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAA 
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG 
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT 
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG 
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC 
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC 
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG 
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC 
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC 
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG 
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG 
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG 
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC 
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG 
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT 
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC 
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TFR2 ( NM_001206855.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193784.1 Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu106955
Clone ID Related Accession (Same CDS sequence)	NM_001206855.2
Accession Version	NM_001206855.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	transferrin receptor protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC099394.6. On Aug 25, 2018 this sequence version replaced NM_001206855.1. Transcript Variant: This variant (2) differs at the 5' end compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in an isoform (2, also known as beta) with a shorter N-terminus (lacking the transmembrane domain) compared to isoform 1. While there is transcript support for this variant (PMID:10409623), the protein is predicted. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.94578.1, SRR1803611.70407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG 
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC 
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG 
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG 
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG 
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA 
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC 
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT 
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC 
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG 
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC 
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC 
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG 
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC 
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAG 
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG 
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT 
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG 
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC 
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC 
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG 
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC 
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC 
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG 
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG 
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG 
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC 
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG 
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT 
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC 
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193784.1
CDS	135..2027
Translation	MAALTQDIRAALSRQKLDHVWTDTHYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDPDVYCPYSAIGNVTGELVYAHYGRPEDLQDLRARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEPADFSQDPPKPSLSSQQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVASSGLPSIPAQPISADIASRLLRKLKGPVAPQEWQGSLLGSPYHLGPGPRLRLVVNNHRTSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTSLIESVLKQVDSPNHSGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAFVGVPAVEFSFMEDDQAYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLLRSNSSGTPGATSSTGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Target ORF information:

RefSeq Version	NM_001206855.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206855.2

ORF Insert Sequence:

ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG 
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC 
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG 
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG 
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG 
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA 
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC 
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT 
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC 
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG 
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC 
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC 
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG 
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC 
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAG 
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG 
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT 
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG 
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC 
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC 
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG 
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC 
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC 
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG 
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG 
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG 
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC 
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG 
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT 
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC 
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical significance of TFR2 and EPOR expression in bone marrow cells in myelodysplastic syndromes.
British journal of haematology176(3)491-495(2017 Feb)
Di Savino A,Gaidano V,Palmieri A,Crasto F,Volpengo A,Lorenzatti R,Scaravaglio P,Manello A,Nicoli P,Gottardi E,Saglio G,Cilloni D,De Gobbi M

Next-generation sequencing of hereditary hemochromatosis-related genes: Novel likely pathogenic variants found in the Portuguese population.
Blood cells, molecules & diseases6110-5(2016 Oct)
Faria R,Silva B,Silva C,Loureiro P,Queiroz A,Fraga S,Esteves J,Mendes D,Fleming R,Vieira L,Gon?alves J,Faustino P

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells.
Blood cells, molecules & diseases6137-45(2016 Oct)
Mehta K,Busbridge M,Renshaw D,Evans RW,Farnaud S,Patel VB

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TFR2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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