PPP1R11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PPP1R11
Entrez Gene ID	6992
Full Name	protein phosphatase 1 regulatory inhibitor subunit 11
Synonyms	CFAP255,HCG-V,HCGV,IPP3,TCTE5,TCTEX5
General protein information	Preferred Names protein phosphatase 1 regulatory inhibitor subunit 11 Names protein phosphatase 1 regulatory subunit 11 HCG V hemochromatosis candidate gene V protein inhibitor-3 protein phosphatase 1, regulatory (inhibitor) subunit 11 protein phosphatase inhibitor 3 t-complex-associated-testis-expressed 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.1
Summary	This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008].
Disorder MIM:	606670

mRNA and Protein(s)

mRNA	Protein	Name
NM_021959.2	NP_068778.1	protein phosphatase 1 regulatory subunit 11
NM_021959.3	NP_068778.1	E3 ubiquitin-protein ligase PPP1R11
XM_006715174.4	XP_006715237.1	E3 ubiquitin-protein ligase PPP1R11 isoform X1
XM_006715174.3	XP_006715237.1	protein phosphatase 1 regulatory subunit 11 isoform X1

Pathways from BioSystems

Homologies

	PPP1R11	NP_001040601.1
Canis lupus familiaris (dog)	PPP1R11	XP_849792.1
Mus musculus (house mouse)	Ppp1r11	NP_083908.1
Danio rerio (zebrafish)	ppp1r11	NP_001017627.1
Pan troglodytes (chimpanzee)	PPP1R11	NP_001065285.1
Rattus norvegicus (Norway rat)	Ppp1r11	NP_997707.2
Homo sapiens (human)	PPP1R11	NP_068778.1
Bos taurus (cattle)	PPP1R11	NP_001093765.1
Xenopus tropicalis (tropical clawed frog)	ppp1r11	NP_001004815.1

Gene Ontology
Bibliography

Related articles in PubMed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Yadav L, Tamene F, G??s H, van Drogen A, Katainen R, Aebersold R, Gstaiger M, Varjosalo M
Cell systems4(4)430-444.e5(2017 Apr)

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.
McKelvey AC, Lear TB, Dunn SR, Evankovich J, Londino JD, Bednash JS, Zhang Y, McVerry BJ, Liu Y, Chen BB
eLife5(2016 11)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.
Eiteneuer A, Seiler J, Weith M, Beullens M, Lesage B, Krenn V, Musacchio A, Bollen M, Meyer H
The EMBO journal33(22)2704-20(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Lentiviral gene transfer or knockdown of PPP1R11 in mouse lungs significantly affects lung inflammation and the clearance of Staphylococcus aureus. There is a negative correlation between PPP1R11 and TLR2 levels in white blood cell samples isolated from patients with Staphylococcus aureus infections
Title: RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.

a model in which I3 regulates an SDS22-mediated PP1 activation step in solution that precedes SDS22 dissociation and transfer of PP1 to kinetochores, and which is required for PP1 to efficiently antagonize Aurora B.
Title: Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.

Observational study of gene-disease association. (HuGE Navigator)
Title: High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

Inh3 has two domains that are required for its interaction with PP1.
Title: Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1.

inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response
Title: Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response.

The following PPP1R11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP1R11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26040	NM_021959.3 Latest version!	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu40447	XM_006715174.4 Latest version!	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu26040	NM_021959.2	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu40447	XM_006715174.3	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PPP1R11 ( NM_021959.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_068778.1 Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.

Price & Availability↑

CloneID	OHu26040
Clone ID Related Accession (Same CDS sequence)	NM_021959.2 , NM_021959.3
Accession Version	NM_021959.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB126242.1 and AL669914.2. On Jun 23, 2006 this sequence version replaced NM_021959.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X81003.1, SRR1163658.368322.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGAGG CAGGGGCTGG GCTGAGCGAG ACCGTCACTG AGACAACGGT TACCGTGACA 
ACCGAGCCCG AGAACCGGAG CCTTACCATC AAACTTCGGA AACGGAAGCC AGAGAAAAAG 
GTAGAATGGA CAAGTGACAC TGTGGACAAT GAACACATGG GCCGCCGCTC ATCCAAATGC 
TGCTGTATTT ATGAGAAACC TCGGGCCTTT GGCGAGAGCT CCACGGAAAG TGATGAGGAG 
GAAGAAGAGG GCTGTGGTCA TACACACTGT GTACGTGGCC ACCGCAAAGG ACGGCGTCGT 
GCAACCCTAG GACCGACCCC CACCACCCCT CCCCAGCCTC CTGACCCTTC CCAGCCCCCT 
CCAGGGCCAA TGCAGCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068778.1
CDS	257..637
Translation	MAEAGAGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPPPGPMQH

Target ORF information:

RefSeq Version	NM_021959.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021959.2

ORF Insert Sequence:

ATGGCCGAGG CAGGGGCTGG GCTGAGCGAG ACCGTCACTG AGACAACGGT TACCGTGACA 
ACCGAGCCCG AGAACCGGAG CCTTACCATC AAACTTCGGA AACGGAAGCC AGAGAAAAAG 
GTAGAATGGA CAAGTGACAC TGTGGACAAT GAACACATGG GCCGCCGCTC ATCCAAATGC 
TGCTGTATTT ATGAGAAACC TCGGGCCTTT GGCGAGAGCT CCACGGAAAG TGATGAGGAG 
GAAGAAGAGG GCTGTGGTCA TACACACTGT GTACGTGGCC ACCGCAAAGG ACGGCGTCGT 
GCAACCCTAG GACCGACCCC CACCACCCCT CCCCAGCCTC CTGACCCTTC CCAGCCCCCT 
CCAGGGCCAA TGCAGCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R11 ( NM_021959.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068778.1 Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.

Price & Availability↑

CloneID	OHu26040
Clone ID Related Accession (Same CDS sequence)	NM_021959.2 , NM_021959.3
Accession Version	NM_021959.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase PPP1R11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB126242.1 and AL669914.2. On Nov 23, 2018 this sequence version replaced NM_021959.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1144568.1, SRR3476690.458544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000376772.8/ ENSP00000365963.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGAGG CAGGGGCTGG GCTGAGCGAG ACCGTCACTG AGACAACGGT TACCGTGACA 
ACCGAGCCCG AGAACCGGAG CCTTACCATC AAACTTCGGA AACGGAAGCC AGAGAAAAAG 
GTAGAATGGA CAAGTGACAC TGTGGACAAT GAACACATGG GCCGCCGCTC ATCCAAATGC 
TGCTGTATTT ATGAGAAACC TCGGGCCTTT GGCGAGAGCT CCACGGAAAG TGATGAGGAG 
GAAGAAGAGG GCTGTGGTCA TACACACTGT GTACGTGGCC ACCGCAAAGG ACGGCGTCGT 
GCAACCCTAG GACCGACCCC CACCACCCCT CCCCAGCCTC CTGACCCTTC CCAGCCCCCT 
CCAGGGCCAA TGCAGCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068778.1
CDS	214..594
Translation	MAEAGAGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPPPGPMQH

Target ORF information:

RefSeq Version	NM_021959.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021959.3

ORF Insert Sequence:

ATGGCCGAGG CAGGGGCTGG GCTGAGCGAG ACCGTCACTG AGACAACGGT TACCGTGACA 
ACCGAGCCCG AGAACCGGAG CCTTACCATC AAACTTCGGA AACGGAAGCC AGAGAAAAAG 
GTAGAATGGA CAAGTGACAC TGTGGACAAT GAACACATGG GCCGCCGCTC ATCCAAATGC 
TGCTGTATTT ATGAGAAACC TCGGGCCTTT GGCGAGAGCT CCACGGAAAG TGATGAGGAG 
GAAGAAGAGG GCTGTGGTCA TACACACTGT GTACGTGGCC ACCGCAAAGG ACGGCGTCGT 
GCAACCCTAG GACCGACCCC CACCACCCCT CCCCAGCCTC CTGACCCTTC CCAGCCCCCT 
CCAGGGCCAA TGCAGCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R11 ( XM_006715174.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715237.1 Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40447
Clone ID Related Accession (Same CDS sequence)	XM_006715174.4 , XM_006715174.3
Accession Version	XM_006715174.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase PPP1R11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006715174.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGTCACA CCCGGAAGCG GCGAGCCGGA AGTGGGGAGA ACCGGAGCCT TACCATCAAA 
CTTCGGAAAC GGAAGCCAGA GAAAAAGGTA GAATGGACAA GTGACACTGT GGACAATGAA 
CACATGGGCC GCCGCTCATC CAAATGCTGC TGTATTTATG AGAAACCTCG GGCCTTTGGC 
GAGAGCTCCA CGGAAAGTGA TGAGGAGGAA GAAGAGGGCT GTGGTCATAC ACACTGTGTA 
CGTGGCCACC GCAAAGGACG GCGTCGTGCA ACCCTAGGAC CGACCCCCAC CACCCCTCCC 
CAGCCTCCTG ACCCTTCCCA GCCCCCTCCA GGGCCAATGC AGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715237.1
CDS	242..589
Translation	MRHTRKRRAGSGENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPPPGPMQH

Target ORF information:

RefSeq Version	XM_006715174.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715174.4

ORF Insert Sequence:

ATGCGTCACA CCCGGAAGCG GCGAGCCGGA AGTGGGGAGA ACCGGAGCCT TACCATCAAA 
CTTCGGAAAC GGAAGCCAGA GAAAAAGGTA GAATGGACAA GTGACACTGT GGACAATGAA 
CACATGGGCC GCCGCTCATC CAAATGCTGC TGTATTTATG AGAAACCTCG GGCCTTTGGC 
GAGAGCTCCA CGGAAAGTGA TGAGGAGGAA GAAGAGGGCT GTGGTCATAC ACACTGTGTA 
CGTGGCCACC GCAAAGGACG GCGTCGTGCA ACCCTAGGAC CGACCCCCAC CACCCCTCCC 
CAGCCTCCTG ACCCTTCCCA GCCCCCTCCA GGGCCAATGC AGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R11 ( XM_006715174.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715237.1 Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40447
Clone ID Related Accession (Same CDS sequence)	XM_006715174.4 , XM_006715174.3
Accession Version	XM_006715174.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715174.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGTCACA CCCGGAAGCG GCGAGCCGGA AGTGGGGAGA ACCGGAGCCT TACCATCAAA 
CTTCGGAAAC GGAAGCCAGA GAAAAAGGTA GAATGGACAA GTGACACTGT GGACAATGAA 
CACATGGGCC GCCGCTCATC CAAATGCTGC TGTATTTATG AGAAACCTCG GGCCTTTGGC 
GAGAGCTCCA CGGAAAGTGA TGAGGAGGAA GAAGAGGGCT GTGGTCATAC ACACTGTGTA 
CGTGGCCACC GCAAAGGACG GCGTCGTGCA ACCCTAGGAC CGACCCCCAC CACCCCTCCC 
CAGCCTCCTG ACCCTTCCCA GCCCCCTCCA GGGCCAATGC AGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715237.1
CDS	247..594
Translation	MRHTRKRRAGSGENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPPPGPMQH

Target ORF information:

RefSeq Version	XM_006715174.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory inhibitor subunit 11 (PPP1R11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715174.3

ORF Insert Sequence:

ATGCGTCACA CCCGGAAGCG GCGAGCCGGA AGTGGGGAGA ACCGGAGCCT TACCATCAAA 
CTTCGGAAAC GGAAGCCAGA GAAAAAGGTA GAATGGACAA GTGACACTGT GGACAATGAA 
CACATGGGCC GCCGCTCATC CAAATGCTGC TGTATTTATG AGAAACCTCG GGCCTTTGGC 
GAGAGCTCCA CGGAAAGTGA TGAGGAGGAA GAAGAGGGCT GTGGTCATAC ACACTGTGTA 
CGTGGCCACC GCAAAGGACG GCGTCGTGCA ACCCTAGGAC CGACCCCCAC CACCCCTCCC 
CAGCCTCCTG ACCCTTCCCA GCCCCCTCCA GGGCCAATGC AGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Cell systems4(4)430-444.e5(2017 Apr)
Yadav L,Tamene F,G??s H,van Drogen A,Katainen R,Aebersold R,Gstaiger M,Varjosalo M

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.
eLife5(2016 11)
McKelvey AC,Lear TB,Dunn SR,Evankovich J,Londino JD,Bednash JS,Zhang Y,McVerry BJ,Liu Y,Chen BB

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.
The EMBO journal33(22)2704-20(2014 Nov)
Eiteneuer A,Seiler J,Weith M,Beullens M,Lesage B,Krenn V,Musacchio A,Bollen M,Meyer H

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PPP1R11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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