Gene Symbol | TCF7L2 |
Entrez Gene ID | 6934 |
Full Name | transcription factor 7 like 2 |
Synonyms | TCF-4,TCF4 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]. |
Disorder MIM: | |
Disorder Html: | {Diabetes mellitus, type 2, susceptibility to}, 125853 (3) |