Gene Symbol | TBCD |
Entrez Gene ID | 6904 |
Full Name | tubulin folding cofactor D |
Synonyms | PEBAT,SSD-1,tfcD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum, 617193 (3) |