KLF5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KLF5
Entrez Gene ID	688
Full Name	Kruppel like factor 5
Synonyms	BTEB2,CKLF,IKLF
General protein information	Preferred Names Kruppel like factor 5 Names Krueppel-like factor 5 (intestinal Kruppel-like factor BTE-binding protein 2 GC box binding protein 2 Klf5C isoform Kruppel-like factor 5 (intestinal) basic transcription element binding protein 2 colon krueppel-like factor colon kruppel-like factor intestinal-enriched krueppel-like factor intestinal-enriched kruppel-like factor transcription factor BTEB2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q22.1
Summary	This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013].
Disorder MIM:	602903

mRNA and Protein(s)

mRNA	Protein	Name
NM_001730.4	NP_001721.2	Krueppel-like factor 5 isoform 1
NM_001286818.1	NP_001273747.1	Krueppel-like factor 5 isoform 2
NM_001730.5	NP_001721.2	Krueppel-like factor 5 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KLF5	NP_001721.2
Pan troglodytes (chimpanzee)	KLF5	XP_001136935.1
Bos taurus (cattle)	KLF5	NP_001077196.1
Mus musculus (house mouse)	Klf5	NP_033899.2
Danio rerio (zebrafish)	LOC100006043	XP_001344916.5
	KLF5	XP_002808197.1
Canis lupus familiaris (dog)	KLF5	XP_849076.1
Rattus norvegicus (Norway rat)	Klf5	NP_445846.2
Gallus gallus (chicken)	KLF5	XP_417013.4
Xenopus tropicalis (tropical clawed frog)	klf5	XP_002931975.2

Gene Ontology
Bibliography

Related articles in PubMed

Minimal essential region for kr?ppel-like factor 5 expression and the regulation by specificity protein 3-GC box binding.
Mihara N, Chiba T, Yamaguchi K, Sudo H, Yagishita H, Imai K
Gene60136-43(2017 Feb)

miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5.
Zhou W, Song F, Wu Q, Liu R, Wang L, Liu C, Peng Y, Mao S, Feng J, Chen C
PloS one12(4)e0176395(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

demonstrate that a 186bp region is the minimal essential region and that Sp3-GC1 binding is essential to the basal expression of KLF5
Title: Minimal essential region for kr?ppel-like factor 5 expression and the regulation by specificity protein 3-GC box binding.

miR-217 suppresses triple-negative breast cancer cell growth, migration, and invasion. MiR-217 suppresses triple-negative breast cancer, at least partially, through down-regulating the KLF5 expression.
Title: miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5.

Data reveal that the presence of rs200996365, a SNP in high-linkage disequilibrium with rs8102137 residing in the center of a KLF5 motif, alters KLF5 binding to this genomic region and provide evidence that KLF5 binds CCNE1 polymorphic intronic enhancer to confer increased bladder cancer risk.
Title: Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk.

Data suggest both KLF5 and FYN (FYN proto-oncogene) are important in regulation of migration in bladder cancer cells; KLF5 up-regulates cell migration, lamellipodia formation, expression of FYN, and phosphorylation of FAK (focal adhesion kinase).
Title: KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells.

We provide the first evidence that the expression of KLF5 is up-regulated in small airways and pulmonary vessels of patients with COPD and may be involved in the tissue remodeling of COPD.
Title: Possible role of Kr?ppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease.

The following KLF5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLF5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21278	NM_001730.5 Latest version!	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu21324	NM_001286818.1 Latest version!	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu21278	NM_001730.4	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KLF5 ( NM_001730.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001721.2 Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21278
Clone ID Related Accession (Same CDS sequence)	NM_001730.4 , NM_001730.5
Accession Version	NM_001730.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-10
Organism	Homo sapiens(human)
Product	Krueppel-like factor 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF132818.1, BC007695.1, BC014302.2, AK131397.1 and BM982025.1. On Nov 16, 2013 this sequence version replaced NM_001730.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF132818.1, AF287272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACAA GGGTGCTGAG CATGAGCGCC CGCCTGGGAC CCGTGCCCCA GCCGCCGGCG 
CCGCAGGACG AGCCGGTGTT CGCGCAGCTC AAGCCGGTGC TGGGCGCCGC GAATCCGGCC 
CGCGACGCGG CGCTCTTCCC CGGCGAGGAG CTGAAGCACG CGCACCACCG CCCGCAGGCG 
CAGCCCGCGC CCGCGCAGGC CCCGCAGCCG GCCCAGCCGC CCGCCACCGG CCCGCGGCTG 
CCTCCAGAGG ACCTGGTCCA GACAAGATGT GAAATGGAGA AGTATCTGAC ACCTCAGCTT 
CCTCCAGTTC CTATAATTCC AGAGCATAAA AAGTATAGAC GAGACAGTGC CTCAGTCGTA 
GACCAGTTCT TCACTGACAC TGAAGGGTTA CCTTACAGTA TCAACATGAA CGTCTTCCTC 
CCTGACATCA CTCACCTGAG AACTGGCCTC TACAAATCCC AGAGACCGTG CGTAACACAC 
ATCAAGACAG AACCTGTTGC CATTTTCAGC CACCAGAGTG AAACGACTGC CCCTCCTCCG 
GCCCCGACCC AGGCCCTCCC TGAGTTCACC AGTATATTCA GCTCACACCA GACCGCAGCT 
CCAGAGGTGA ACAATATTTT CATCAAACAA GAACTTCCTA CACCAGATCT TCATCTTTCT 
GTCCCTACCC AGCAGGGCCA CCTGTACCAG CTACTGAATA CACCGGATCT AGATATGCCC 
AGTTCTACAA ATCAGACAGC AGCAATGGAC ACTCTTAATG TTTCTATGTC AGCTGCCATG 
GCAGGCCTTA ACACACACAC CTCTGCTGTT CCGCAGACTG CAGTGAAACA ATTCCAGGGC 
ATGCCCCCTT GCACATACAC AATGCCAAGT CAGTTTCTTC CACAACAGGC CACTTACTTT 
CCCCCGTCAC CACCAAGCTC AGAGCCTGGA AGTCCAGATA GACAAGCAGA GATGCTCCAG 
AATTTAACCC CACCTCCATC CTATGCTGCT ACAATTGCTT CTAAACTGGC AATTCACAAT 
CCAAATTTAC CCACCACCCT GCCAGTTAAC TCACAAAACA TCCAACCTGT CAGATACAAT 
AGAAGGAGTA ACCCCGATTT GGAGAAACGA CGCATCCACT ACTGCGATTA CCCTGGTTGC 
ACAAAAGTTT ATACCAAGTC TTCTCATTTA AAAGCTCACC TGAGGACTCA CACTGGTGAA 
AAGCCATACA AGTGTACCTG GGAAGGCTGC GACTGGAGGT TCGCGCGATC GGATGAGCTG 
ACCCGCCACT ACCGGAAGCA CACAGGCGCC AAGCCCTTCC AGTGCGGGGT GTGCAACCGC 
AGCTTCTCGC GCTCTGACCA CCTGGCCCTG CATATGAAGA GGCACCAGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001721.2
CDS	537..1910
Translation	MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

Target ORF information:

RefSeq Version	NM_001730.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001730.4

ORF Insert Sequence:

ATGGCTACAA GGGTGCTGAG CATGAGCGCC CGCCTGGGAC CCGTGCCCCA GCCGCCGGCG 
CCGCAGGACG AGCCGGTGTT CGCGCAGCTC AAGCCGGTGC TGGGCGCCGC GAATCCGGCC 
CGCGACGCGG CGCTCTTCCC CGGCGAGGAG CTGAAGCACG CGCACCACCG CCCGCAGGCG 
CAGCCCGCGC CCGCGCAGGC CCCGCAGCCG GCCCAGCCGC CCGCCACCGG CCCGCGGCTG 
CCTCCAGAGG ACCTGGTCCA GACAAGATGT GAAATGGAGA AGTATCTGAC ACCTCAGCTT 
CCTCCAGTTC CTATAATTCC AGAGCATAAA AAGTATAGAC GAGACAGTGC CTCAGTCGTA 
GACCAGTTCT TCACTGACAC TGAAGGGTTA CCTTACAGTA TCAACATGAA CGTCTTCCTC 
CCTGACATCA CTCACCTGAG AACTGGCCTC TACAAATCCC AGAGACCGTG CGTAACACAC 
ATCAAGACAG AACCTGTTGC CATTTTCAGC CACCAGAGTG AAACGACTGC CCCTCCTCCG 
GCCCCGACCC AGGCCCTCCC TGAGTTCACC AGTATATTCA GCTCACACCA GACCGCAGCT 
CCAGAGGTGA ACAATATTTT CATCAAACAA GAACTTCCTA CACCAGATCT TCATCTTTCT 
GTCCCTACCC AGCAGGGCCA CCTGTACCAG CTACTGAATA CACCGGATCT AGATATGCCC 
AGTTCTACAA ATCAGACAGC AGCAATGGAC ACTCTTAATG TTTCTATGTC AGCTGCCATG 
GCAGGCCTTA ACACACACAC CTCTGCTGTT CCGCAGACTG CAGTGAAACA ATTCCAGGGC 
ATGCCCCCTT GCACATACAC AATGCCAAGT CAGTTTCTTC CACAACAGGC CACTTACTTT 
CCCCCGTCAC CACCAAGCTC AGAGCCTGGA AGTCCAGATA GACAAGCAGA GATGCTCCAG 
AATTTAACCC CACCTCCATC CTATGCTGCT ACAATTGCTT CTAAACTGGC AATTCACAAT 
CCAAATTTAC CCACCACCCT GCCAGTTAAC TCACAAAACA TCCAACCTGT CAGATACAAT 
AGAAGGAGTA ACCCCGATTT GGAGAAACGA CGCATCCACT ACTGCGATTA CCCTGGTTGC 
ACAAAAGTTT ATACCAAGTC TTCTCATTTA AAAGCTCACC TGAGGACTCA CACTGGTGAA 
AAGCCATACA AGTGTACCTG GGAAGGCTGC GACTGGAGGT TCGCGCGATC GGATGAGCTG 
ACCCGCCACT ACCGGAAGCA CACAGGCGCC AAGCCCTTCC AGTGCGGGGT GTGCAACCGC 
AGCTTCTCGC GCTCTGACCA CCTGGCCCTG CATATGAAGA GGCACCAGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLF5 ( NM_001730.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001721.2 Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21278
Clone ID Related Accession (Same CDS sequence)	NM_001730.4 , NM_001730.5
Accession Version	NM_001730.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	Krueppel-like factor 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF132818.1, BC007695.1, BC014302.2, AK131397.1 and BM982025.1. On Nov 23, 2018 this sequence version replaced NM_001730.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF132818.1, SRR1660805.54979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377687.6/ ENSP00000366915.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTACAA GGGTGCTGAG CATGAGCGCC CGCCTGGGAC CCGTGCCCCA GCCGCCGGCG 
CCGCAGGACG AGCCGGTGTT CGCGCAGCTC AAGCCGGTGC TGGGCGCCGC GAATCCGGCC 
CGCGACGCGG CGCTCTTCCC CGGCGAGGAG CTGAAGCACG CGCACCACCG CCCGCAGGCG 
CAGCCCGCGC CCGCGCAGGC CCCGCAGCCG GCCCAGCCGC CCGCCACCGG CCCGCGGCTG 
CCTCCAGAGG ACCTGGTCCA GACAAGATGT GAAATGGAGA AGTATCTGAC ACCTCAGCTT 
CCTCCAGTTC CTATAATTCC AGAGCATAAA AAGTATAGAC GAGACAGTGC CTCAGTCGTA 
GACCAGTTCT TCACTGACAC TGAAGGGTTA CCTTACAGTA TCAACATGAA CGTCTTCCTC 
CCTGACATCA CTCACCTGAG AACTGGCCTC TACAAATCCC AGAGACCGTG CGTAACACAC 
ATCAAGACAG AACCTGTTGC CATTTTCAGC CACCAGAGTG AAACGACTGC CCCTCCTCCG 
GCCCCGACCC AGGCCCTCCC TGAGTTCACC AGTATATTCA GCTCACACCA GACCGCAGCT 
CCAGAGGTGA ACAATATTTT CATCAAACAA GAACTTCCTA CACCAGATCT TCATCTTTCT 
GTCCCTACCC AGCAGGGCCA CCTGTACCAG CTACTGAATA CACCGGATCT AGATATGCCC 
AGTTCTACAA ATCAGACAGC AGCAATGGAC ACTCTTAATG TTTCTATGTC AGCTGCCATG 
GCAGGCCTTA ACACACACAC CTCTGCTGTT CCGCAGACTG CAGTGAAACA ATTCCAGGGC 
ATGCCCCCTT GCACATACAC AATGCCAAGT CAGTTTCTTC CACAACAGGC CACTTACTTT 
CCCCCGTCAC CACCAAGCTC AGAGCCTGGA AGTCCAGATA GACAAGCAGA GATGCTCCAG 
AATTTAACCC CACCTCCATC CTATGCTGCT ACAATTGCTT CTAAACTGGC AATTCACAAT 
CCAAATTTAC CCACCACCCT GCCAGTTAAC TCACAAAACA TCCAACCTGT CAGATACAAT 
AGAAGGAGTA ACCCCGATTT GGAGAAACGA CGCATCCACT ACTGCGATTA CCCTGGTTGC 
ACAAAAGTTT ATACCAAGTC TTCTCATTTA AAAGCTCACC TGAGGACTCA CACTGGTGAA 
AAGCCATACA AGTGTACCTG GGAAGGCTGC GACTGGAGGT TCGCGCGATC GGATGAGCTG 
ACCCGCCACT ACCGGAAGCA CACAGGCGCC AAGCCCTTCC AGTGCGGGGT GTGCAACCGC 
AGCTTCTCGC GCTCTGACCA CCTGGCCCTG CATATGAAGA GGCACCAGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001721.2
CDS	324..1697
Translation	MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

Target ORF information:

RefSeq Version	NM_001730.5
Organism	Homo sapiens(human)
Definition	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001730.5

ORF Insert Sequence:

ATGGCTACAA GGGTGCTGAG CATGAGCGCC CGCCTGGGAC CCGTGCCCCA GCCGCCGGCG 
CCGCAGGACG AGCCGGTGTT CGCGCAGCTC AAGCCGGTGC TGGGCGCCGC GAATCCGGCC 
CGCGACGCGG CGCTCTTCCC CGGCGAGGAG CTGAAGCACG CGCACCACCG CCCGCAGGCG 
CAGCCCGCGC CCGCGCAGGC CCCGCAGCCG GCCCAGCCGC CCGCCACCGG CCCGCGGCTG 
CCTCCAGAGG ACCTGGTCCA GACAAGATGT GAAATGGAGA AGTATCTGAC ACCTCAGCTT 
CCTCCAGTTC CTATAATTCC AGAGCATAAA AAGTATAGAC GAGACAGTGC CTCAGTCGTA 
GACCAGTTCT TCACTGACAC TGAAGGGTTA CCTTACAGTA TCAACATGAA CGTCTTCCTC 
CCTGACATCA CTCACCTGAG AACTGGCCTC TACAAATCCC AGAGACCGTG CGTAACACAC 
ATCAAGACAG AACCTGTTGC CATTTTCAGC CACCAGAGTG AAACGACTGC CCCTCCTCCG 
GCCCCGACCC AGGCCCTCCC TGAGTTCACC AGTATATTCA GCTCACACCA GACCGCAGCT 
CCAGAGGTGA ACAATATTTT CATCAAACAA GAACTTCCTA CACCAGATCT TCATCTTTCT 
GTCCCTACCC AGCAGGGCCA CCTGTACCAG CTACTGAATA CACCGGATCT AGATATGCCC 
AGTTCTACAA ATCAGACAGC AGCAATGGAC ACTCTTAATG TTTCTATGTC AGCTGCCATG 
GCAGGCCTTA ACACACACAC CTCTGCTGTT CCGCAGACTG CAGTGAAACA ATTCCAGGGC 
ATGCCCCCTT GCACATACAC AATGCCAAGT CAGTTTCTTC CACAACAGGC CACTTACTTT 
CCCCCGTCAC CACCAAGCTC AGAGCCTGGA AGTCCAGATA GACAAGCAGA GATGCTCCAG 
AATTTAACCC CACCTCCATC CTATGCTGCT ACAATTGCTT CTAAACTGGC AATTCACAAT 
CCAAATTTAC CCACCACCCT GCCAGTTAAC TCACAAAACA TCCAACCTGT CAGATACAAT 
AGAAGGAGTA ACCCCGATTT GGAGAAACGA CGCATCCACT ACTGCGATTA CCCTGGTTGC 
ACAAAAGTTT ATACCAAGTC TTCTCATTTA AAAGCTCACC TGAGGACTCA CACTGGTGAA 
AAGCCATACA AGTGTACCTG GGAAGGCTGC GACTGGAGGT TCGCGCGATC GGATGAGCTG 
ACCCGCCACT ACCGGAAGCA CACAGGCGCC AAGCCCTTCC AGTGCGGGGT GTGCAACCGC 
AGCTTCTCGC GCTCTGACCA CCTGGCCCTG CATATGAAGA GGCACCAGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLF5 ( NM_001286818.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273747.1 Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21324
Clone ID Related Accession (Same CDS sequence)	NM_001286818.1
Accession Version	NM_001286818.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	Krueppel-like factor 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302280.1, AF132818.1, AK131397.1 and BM982025.1. On Nov 16, 2013 this sequence version replaced XM_005266508.1. Transcript Variant: This variant (2, also known as tKLF5) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF208215.1, AK302280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAGT ATCTGACACC TCAGCTTCCT CCAGTTCCTA TAATTCCAGA GCATAAAAAG 
TATAGACGAG ACAGTGCCTC AGTCGTAGAC CAGTTCTTCA CTGACACTGA AGGGTTACCT 
TACAGTATCA ACATGAACGT CTTCCTCCCT GACATCACTC ACCTGAGAAC TGGCCTCTAC 
AAATCCCAGA GACCGTGCGT AACACACATC AAGACAGAAC CTGTTGCCAT TTTCAGCCAC 
CAGAGTGAAA CGACTGCCCC TCCTCCGGCC CCGACCCAGG CCCTCCCTGA GTTCACCAGT 
ATATTCAGCT CACACCAGAC CGCAGCTCCA GAGGTGAACA ATATTTTCAT CAAACAAGAA 
CTTCCTACAC CAGATCTTCA TCTTTCTGTC CCTACCCAGC AGGGCCACCT GTACCAGCTA 
CTGAATACAC CGGATCTAGA TATGCCCAGT TCTACAAATC AGACAGCAGC AATGGACACT 
CTTAATGTTT CTATGTCAGC TGCCATGGCA GGCCTTAACA CACACACCTC TGCTGTTCCG 
CAGACTGCAG TGAAACAATT CCAGGGCATG CCCCCTTGCA CATACACAAT GCCAAGTCAG 
TTTCTTCCAC AACAGGCCAC TTACTTTCCC CCGTCACCAC CAAGCTCAGA GCCTGGAAGT 
CCAGATAGAC AAGCAGAGAT GCTCCAGAAT TTAACCCCAC CTCCATCCTA TGCTGCTACA 
ATTGCTTCTA AACTGGCAAT TCACAATCCA AATTTACCCA CCACCCTGCC AGTTAACTCA 
CAAAACATCC AACCTGTCAG ATACAATAGA AGGAGTAACC CCGATTTGGA GAAACGACGC 
ATCCACTACT GCGATTACCC TGGTTGCACA AAAGTTTATA CCAAGTCTTC TCATTTAAAA 
GCTCACCTGA GGACTCACAC TGGTGAAAAG CCATACAAGT GTACCTGGGA AGGCTGCGAC 
TGGAGGTTCG CGCGATCGGA TGAGCTGACC CGCCACTACC GGAAGCACAC AGGCGCCAAG 
CCCTTCCAGT GCGGGGTGTG CAACCGCAGC TTCTCGCGCT CTGACCACCT GGCCCTGCAT 
ATGAAGAGGC ACCAGAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273747.1
CDS	196..1296
Translation	MEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

Target ORF information:

RefSeq Version	NM_001286818.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Kruppel like factor 5 (KLF5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286818.1

ORF Insert Sequence:

ATGGAGAAGT ATCTGACACC TCAGCTTCCT CCAGTTCCTA TAATTCCAGA GCATAAAAAG 
TATAGACGAG ACAGTGCCTC AGTCGTAGAC CAGTTCTTCA CTGACACTGA AGGGTTACCT 
TACAGTATCA ACATGAACGT CTTCCTCCCT GACATCACTC ACCTGAGAAC TGGCCTCTAC 
AAATCCCAGA GACCGTGCGT AACACACATC AAGACAGAAC CTGTTGCCAT TTTCAGCCAC 
CAGAGTGAAA CGACTGCCCC TCCTCCGGCC CCGACCCAGG CCCTCCCTGA GTTCACCAGT 
ATATTCAGCT CACACCAGAC CGCAGCTCCA GAGGTGAACA ATATTTTCAT CAAACAAGAA 
CTTCCTACAC CAGATCTTCA TCTTTCTGTC CCTACCCAGC AGGGCCACCT GTACCAGCTA 
CTGAATACAC CGGATCTAGA TATGCCCAGT TCTACAAATC AGACAGCAGC AATGGACACT 
CTTAATGTTT CTATGTCAGC TGCCATGGCA GGCCTTAACA CACACACCTC TGCTGTTCCG 
CAGACTGCAG TGAAACAATT CCAGGGCATG CCCCCTTGCA CATACACAAT GCCAAGTCAG 
TTTCTTCCAC AACAGGCCAC TTACTTTCCC CCGTCACCAC CAAGCTCAGA GCCTGGAAGT 
CCAGATAGAC AAGCAGAGAT GCTCCAGAAT TTAACCCCAC CTCCATCCTA TGCTGCTACA 
ATTGCTTCTA AACTGGCAAT TCACAATCCA AATTTACCCA CCACCCTGCC AGTTAACTCA 
CAAAACATCC AACCTGTCAG ATACAATAGA AGGAGTAACC CCGATTTGGA GAAACGACGC 
ATCCACTACT GCGATTACCC TGGTTGCACA AAAGTTTATA CCAAGTCTTC TCATTTAAAA 
GCTCACCTGA GGACTCACAC TGGTGAAAAG CCATACAAGT GTACCTGGGA AGGCTGCGAC 
TGGAGGTTCG CGCGATCGGA TGAGCTGACC CGCCACTACC GGAAGCACAC AGGCGCCAAG 
CCCTTCCAGT GCGGGGTGTG CAACCGCAGC TTCTCGCGCT CTGACCACCT GGCCCTGCAT 
ATGAAGAGGC ACCAGAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Minimal essential region for kr?ppel-like factor 5 expression and the regulation by specificity protein 3-GC box binding.
Gene60136-43(2017 Feb)
Mihara N,Chiba T,Yamaguchi K,Sudo H,Yagishita H,Imai K

miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5.
PloS one12(4)e0176395(2017)
Zhou W,Song F,Wu Q,Liu R,Wang L,Liu C,Peng Y,Mao S,Feng J,Chen C

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

KLF5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報