Gene Symbol | SUV39H1 |
Entrez Gene ID | 6839 |
Full Name | suppressor of variegation 3-9 homolog 1 |
Synonyms | H3-K9-HMTase 1,KMT1A,MG44,SUV39H |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. |
Disorder MIM: |