Gene Symbol | AURKC |
Entrez Gene ID | 6795 |
Full Name | aurora kinase C |
Synonyms | AIE2,AIK3,ARK3,AurC,HEL-S-90,SPGF5,STK13,aurora-C |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Spermatogenic failure 5, 243060 (3) |