STIM1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STIM1
Entrez Gene ID	6786
Full Name	stromal interaction molecule 1
Synonyms	D11S4896E,GOK,IMD10,STRMK,TAM,TAM1
General protein information	Preferred Names stromal interaction molecule 1 Names stromal interaction molecule 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4
Summary	This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013].
Disorder MIM:	605921
Disorder Html:	Immunodeficiency 10, 612783 (3); Myopathy, tubular aggregate, 1 160565 (3); Stormorken syndrome, 185070 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001277961.1	NP_001264890.1	stromal interaction molecule 1 isoform 1 precursor
NM_001277962.1	NP_001264891.1	stromal interaction molecule 1 isoform 3 precursor
NM_003156.3	NP_003147.2	stromal interaction molecule 1 isoform 2 precursor
NM_001277962.2	NP_001264891.1	stromal interaction molecule 1 isoform 3 precursor

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	stim-1	NP_741073.1
Danio rerio (zebrafish)	stim1a	NP_001038264.1
Xenopus tropicalis (tropical clawed frog)	stim1	NP_991397.1
Pan troglodytes (chimpanzee)	STIM1	XP_003951854.1
Bos taurus (cattle)	STIM1	NP_001030486.1
Mus musculus (house mouse)	Stim1	NP_033313.2
Rattus norvegicus (Norway rat)	Stim1	NP_001101966.2
Drosophila melanogaster (fruit fly)	Stim	NP_523357.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000175	XP_310961.4
Homo sapiens (human)	STIM1	NP_001264890.1
	STIM1	XP_001112949.1
Canis lupus familiaris (dog)	STIM1	XP_005633633.1
Gallus gallus (chicken)	STIM1	NP_001026009.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1.
Kilch T, Alansary D, Peglow M, D?rr K, Rychkov G, Rieger H, Peinelt C, Niemeyer BA
The Journal of biological chemistry288(3)1653-64(2013 Jan)

STIM proteins: dynamic calcium signal transducers.
Soboloff J, Rothberg BS, Madesh M, Gill DL
Nature reviews. Molecular cell biology13(9)549-65(2012 Sep)

STIM1L is a new actin-binding splice variant involved in fast repetitive Ca2+ release.
Darbellay B, Arnaudeau S, Bader CR, Konig S, Bernheim L
The Journal of cell biology194(2)335-46(2011 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RASSF4 controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes.
Title: RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P

The STIM1 protein play important roles in TGF-beta-induced EMT and these effects are related to both store-operated calcium entry and non-store-operated calcium entry.
Title: STIM1 and STIM2 differently regulate endogenous Ca

STIM1-induced Ca(2+) signaling activates Pyk2 to inhibit the interaction of VE-PTP and VE-cadherin and hence increase endothelial permeability.
Title: Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca

STIM1L and TRPC1/4 are working together in myotubes to ensure efficient store refilling and a proper differentiation program.
Title: TRPC1 and TRPC4 channels functionally interact with STIM1L to promote myogenesis and maintain fast repetitive Ca

conformational changes in STIM1 upon calcium release
Title: Molecular Dynamics Simulations of Membrane-Bound STIM1 to Investigate Conformational Changes during STIM1 Activation upon Calcium Release.

The following STIM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STIM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18426	NM_003156.3 Latest version!	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu21429	NM_001277961.1 Latest version!	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu21722	NM_001277962.2 Latest version!	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu21722	NM_001277962.1	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STIM1 ( NM_003156.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003147.2 Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18426
Clone ID Related Accession (Same CDS sequence)	NM_003156.3
Accession Version	NM_003156.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	stromal interaction molecule 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U52426.1, BC021300.2, BI820627.1, CX873095.1 and BM127091.1. This sequence is a reference standard in the RefSeqGene project. On Jan 24, 2009 this sequence version replaced NM_003156.2. Transcript Variant: This variant (2, also known as STIM1S) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC021300.2, U52426.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GGGATTTGAC CCATTCCGAT 
TCGGAGTCCT CCCTCCACAT GAGTGACCGC CAGCGTGTGG CCCCCAAACC TCCTCAGATG 
AGCCGTGCTG CAGACGAGGC TCTCAATGCC ATGACTTCCA ATGGCAGCCA CCGGCTGATC 
GAGGGGGTCC ACCCAGGGTC TCTGGTGGAG AAACTGCCTG ACAGCCCTGC CCTGGCCAAG 
AAGGCATTAC TGGCGCTGAA CCATGGGCTG GACAAGGCCC ACAGCCTGAT GGAGCTGAGC 
CCCTCAGCCC CACCTGGTGG CTCTCCACAT TTGGATTCTT CCCGTTCTCA CAGCCCCAGC 
TCCCCAGACC CAGACACACC ATCTCCAGTT GGGGACAGCC GAGCCCTGCA AGCCAGCCGA 
AACACACGCA TTCCCCACCT GGCTGGCAAG AAGGCTGTGG CTGAGGAGGA TAATGGCTCT 
ATTGGCGAGG AAACAGACTC CAGCCCAGGC CGGAAGAAGT TTCCCCTCAA AATCTTTAAG 
AAGCCTCTTA AGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003147.2
CDS	569..2626
Translation	MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK

Target ORF information:

RefSeq Version	NM_003156.3
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003156.3

ORF Insert Sequence:

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GGGATTTGAC CCATTCCGAT 
TCGGAGTCCT CCCTCCACAT GAGTGACCGC CAGCGTGTGG CCCCCAAACC TCCTCAGATG 
AGCCGTGCTG CAGACGAGGC TCTCAATGCC ATGACTTCCA ATGGCAGCCA CCGGCTGATC 
GAGGGGGTCC ACCCAGGGTC TCTGGTGGAG AAACTGCCTG ACAGCCCTGC CCTGGCCAAG 
AAGGCATTAC TGGCGCTGAA CCATGGGCTG GACAAGGCCC ACAGCCTGAT GGAGCTGAGC 
CCCTCAGCCC CACCTGGTGG CTCTCCACAT TTGGATTCTT CCCGTTCTCA CAGCCCCAGC 
TCCCCAGACC CAGACACACC ATCTCCAGTT GGGGACAGCC GAGCCCTGCA AGCCAGCCGA 
AACACACGCA TTCCCCACCT GGCTGGCAAG AAGGCTGTGG CTGAGGAGGA TAATGGCTCT 
ATTGGCGAGG AAACAGACTC CAGCCCAGGC CGGAAGAAGT TTCCCCTCAA AATCTTTAAG 
AAGCCTCTTA AGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM1 ( NM_001277961.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001264890.1 Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21429
Clone ID Related Accession (Same CDS sequence)	NM_001277961.1
Accession Version	NM_001277961.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Homo sapiens(human)
Product	stromal interaction molecule 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090804.8 and HQ317451.1. Transcript Variant: This variant (1, also known as STIM1L) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HQ317451.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GGTTGGTAGA GGGCGAGGCT 
GGCCACTTCT TGACAAGCCG GGTATCTCTG CGGCGAATGC GCAGCCTTTC ATCTGGACAG 
TCTTTCAGTT CTGAAGGCTA CGGGACCAGC TCTCCATCTG CCTCTGCTGC TGCTTCTTGC 
TCCTCTTCCA TCACCACCAT CACCACTACC ACCACCACCA CCACCACCTT CACCACCGTC 
CATGTCCACC CTGTTTATTA CCACCACAGC ACTTCCTATT TCCTCCAGAT GGAGCCCTAC 
CCTGACACAC CCCCTTCTGA CAGCACCGCT GTGATGCCTG GGCATTCAGA GAGCTTGGGG 
GATTTGACCC ATTCCGATTC GGAGTCCTCC CTCCACATGA GTGACCGCCA GCGTGTGGCC 
CCCAAACCTC CTCAGATGAG CCGTGCTGCA GACGAGGCTC TCAATGCCAT GACTTCCAAT 
GGCAGCCACC GGCTGATCGA GGGGGTCCAC CCAGGGTCTC TGGTGGAGAA ACTGCCTGAC 
AGCCCTGCCC TGGCCAAGAA GGCATTACTG GCGCTGAACC ATGGGCTGGA CAAGGCCCAC 
AGCCTGATGG AGCTGAGCCC CTCAGCCCCA CCTGGTGGCT CTCCACATTT GGATTCTTCC 
CGTTCTCACA GCCCCAGCTC CCCAGACCCA GACACACCAT CTCCAGTTGG GGACAGCCGA 
GCCCTGCAAG CCAGCCGAAA CACACGCATT CCCCACCTGG CTGGCAAGAA GGCTGTGGCT 
GAGGAGGATA ATGGCTCTAT TGGCGAGGAA ACAGACTCCA GCCCAGGCCG GAAGAAGTTT 
CCCCTCAAAA TCTTTAAGAA GCCTCTTAAG AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264890.1
CDS	569..2944
Translation	MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRLVEGEAGHFLTSRVSLRRMRSLSSGQSFSSEGYGTSSPSASAAASCSSSITTITTTTTTTTTFTTVHVHPVYYHHSTSYFLQMEPYPDTPPSDSTAVMPGHSESLGDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGGSPHLDSSRSHSPSSPDPDTPSPVGDSRALQASRNTRIPHLAGKKAVAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK

Target ORF information:

RefSeq Version	NM_001277961.1
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277961.1

ORF Insert Sequence:

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GGTTGGTAGA GGGCGAGGCT 
GGCCACTTCT TGACAAGCCG GGTATCTCTG CGGCGAATGC GCAGCCTTTC ATCTGGACAG 
TCTTTCAGTT CTGAAGGCTA CGGGACCAGC TCTCCATCTG CCTCTGCTGC TGCTTCTTGC 
TCCTCTTCCA TCACCACCAT CACCACTACC ACCACCACCA CCACCACCTT CACCACCGTC 
CATGTCCACC CTGTTTATTA CCACCACAGC ACTTCCTATT TCCTCCAGAT GGAGCCCTAC 
CCTGACACAC CCCCTTCTGA CAGCACCGCT GTGATGCCTG GGCATTCAGA GAGCTTGGGG 
GATTTGACCC ATTCCGATTC GGAGTCCTCC CTCCACATGA GTGACCGCCA GCGTGTGGCC 
CCCAAACCTC CTCAGATGAG CCGTGCTGCA GACGAGGCTC TCAATGCCAT GACTTCCAAT 
GGCAGCCACC GGCTGATCGA GGGGGTCCAC CCAGGGTCTC TGGTGGAGAA ACTGCCTGAC 
AGCCCTGCCC TGGCCAAGAA GGCATTACTG GCGCTGAACC ATGGGCTGGA CAAGGCCCAC 
AGCCTGATGG AGCTGAGCCC CTCAGCCCCA CCTGGTGGCT CTCCACATTT GGATTCTTCC 
CGTTCTCACA GCCCCAGCTC CCCAGACCCA GACACACCAT CTCCAGTTGG GGACAGCCGA 
GCCCTGCAAG CCAGCCGAAA CACACGCATT CCCCACCTGG CTGGCAAGAA GGCTGTGGCT 
GAGGAGGATA ATGGCTCTAT TGGCGAGGAA ACAGACTCCA GCCCAGGCCG GAAGAAGTTT 
CCCCTCAAAA TCTTTAAGAA GCCTCTTAAG AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM1 ( NM_001277962.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001264891.1 Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.

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CloneID	OHu21722
Clone ID Related Accession (Same CDS sequence)	NM_001277962.1 , NM_001277962.2
Accession Version	NM_001277962.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	stromal interaction molecule 1 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090804.8, HQ317451.1, AK314928.1 and U52426.1. Transcript Variant: This variant (3) contains an alternate exon and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting protein (isoform 3) has a distinct C-terminus and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.91723.1, SRR1803615.253242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GAGGATCATC TCTAAAGGCA 
AACAGGCTCT CTAGTAAGGG ATTTGACCCA TTCCGATTCG GAGTCCTCCC TCCACATGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264891.1
CDS	569..2191
Translation	MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRGSSLKANRLSSKGFDPFRFGVLPPHE

Target ORF information:

RefSeq Version	NM_001277962.1
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277962.1

ORF Insert Sequence:

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GAGGATCATC TCTAAAGGCA 
AACAGGCTCT CTAGTAAGGG ATTTGACCCA TTCCGATTCG GAGTCCTCCC TCCACATGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM1 ( NM_001277962.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001264891.1 Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.

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CloneID	OHu21722
Clone ID Related Accession (Same CDS sequence)	NM_001277962.1 , NM_001277962.2
Accession Version	NM_001277962.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	stromal interaction molecule 1 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC090804.8, HQ317451.1, AK314928.1 and U52426.1. On Jun 2, 2019 this sequence version replaced NM_001277962.1. Transcript Variant: This variant (3) contains an alternate exon and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting protein (isoform 3) has a distinct C-terminus and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.91723.1, SRR1803615.253242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GAGGATCATC TCTAAAGGCA 
AACAGGCTCT CTAGTAAGGG ATTTGACCCA TTCCGATTCG GAGTCCTCCC TCCACATGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001264891.1
CDS	608..2230
Translation	MDVCVRLALWLLWGLLLHQGQSLSHSHSEKATGTSSGANSEESTAAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVVQWLITYVELPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRGSSLKANRLSSKGFDPFRFGVLPPHE

Target ORF information:

RefSeq Version	NM_001277962.2
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 1 (STIM1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001277962.2

ORF Insert Sequence:

ATGGATGTAT GCGTCCGTCT TGCCCTGTGG CTCCTCTGGG GACTCCTCCT GCACCAGGGC 
CAGAGCCTCA GCCATAGTCA CAGTGAGAAG GCGACAGGAA CCAGCTCGGG GGCCAACTCT 
GAGGAGTCCA CTGCAGCAGA GTTTTGCCGA ATTGACAAGC CCCTGTGTCA CAGTGAGGAT 
GAGAAACTCA GCTTCGAGGC AGTCCGTAAC ATCCACAAAC TGATGGACGA TGATGCCAAT 
GGTGATGTGG ATGTGGAAGA AAGTGATGAG TTCCTGAGGG AAGACCTCAA TTACCATGAC 
CCAACAGTGA AACACAGCAC CTTCCATGGT GAGGATAAGC TCATCAGCGT GGAGGACCTG 
TGGAAGGCAT GGAAGTCATC AGAAGTATAC AATTGGACCG TGGATGAGGT GGTACAGTGG 
CTGATCACAT ATGTGGAGCT GCCTCAGTAT GAGGAGACCT TCCGGAAGCT GCAGCTCAGT 
GGCCATGCCA TGCCAAGGCT GGCTGTCACC AACACCACCA TGACAGGGAC TGTGCTGAAG 
ATGACAGACC GGAGTCATCG GCAGAAGCTG CAGCTGAAGG CTCTGGATAC AGTGCTCTTT 
GGGCCTCCTC TCTTGACTCG CCATAATCAC CTCAAGGACT TCATGCTGGT GGTGTCTATC 
GTTATTGGTG TGGGCGGCTG CTGGTTTGCC TATATCCAGA ACCGTTACTC CAAGGAGCAC 
ATGAAGAAGA TGATGAAGGA CTTGGAGGGG TTACACCGAG CTGAGCAGAG TCTGCATGAC 
CTTCAGGAAA GGCTGCACAA GGCCCAGGAG GAGCACCGCA CAGTGGAGGT GGAGAAGGTC 
CATCTGGAAA AGAAGCTGCG CGATGAGATC AACCTTGCTA AGCAGGAAGC CCAGCGGCTG 
AAGGAGCTGC GGGAGGGTAC TGAGAATGAG CGGAGCCGCC AAAAATATGC TGAGGAGGAG 
TTGGAGCAGG TTCGGGAGGC CTTGAGGAAA GCAGAGAAGG AGCTAGAATC TCACAGCTCA 
TGGTATGCTC CAGAGGCCCT TCAGAAGTGG CTGCAGCTGA CACATGAGGT GGAGGTGCAA 
TATTACAACA TCAAGAAGCA AAATGCTGAG AAGCAGCTGC TGGTGGCCAA GGAGGGGGCT 
GAGAAGATAA AAAAGAAGAG AAACACACTC TTTGGCACCT TCCACGTGGC CCACAGCTCT 
TCCCTGGATG ATGTAGATCA TAAAATTCTA ACAGCTAAGC AAGCACTGAG CGAGGTGACA 
GCAGCATTGC GGGAGCGCCT GCACCGCTGG CAACAGATCG AGATCCTCTG TGGCTTCCAG 
ATTGTCAACA ACCCTGGCAT CCACTCACTG GTGGCTGCCC TCAACATAGA CCCCAGCTGG 
ATGGGCAGTA CACGCCCCAA CCCTGCTCAC TTCATCATGA CTGACGACGT GGATGACATG 
GATGAGGAGA TTGTGTCTCC CTTGTCCATG CAGTCCCCTA GCCTGCAGAG CAGTGTTCGG 
CAGCGCCTGA CGGAGCCACA GCATGGCCTG GGATCTCAGA GAGGATCATC TCTAAAGGCA 
AACAGGCTCT CTAGTAAGGG ATTTGACCCA TTCCGATTCG GAGTCCTCCC TCCACATGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1.
The Journal of biological chemistry288(3)1653-64(2013 Jan)
Kilch T,Alansary D,Peglow M,D?rr K,Rychkov G,Rieger H,Peinelt C,Niemeyer BA

STIM proteins: dynamic calcium signal transducers.
Nature reviews. Molecular cell biology13(9)549-65(2012 Sep)
Soboloff J,Rothberg BS,Madesh M,Gill DL

STIM1L is a new actin-binding splice variant involved in fast repetitive Ca2+ release.
The Journal of cell biology194(2)335-46(2011 Jul)
Darbellay B,Arnaudeau S,Bader CR,Konig S,Bernheim L

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STIM1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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