SSTR5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SSTR5
Entrez Gene ID	6755
Full Name	somatostatin receptor 5
Synonyms	SS-5-R
General protein information	Preferred Names somatostatin receptor 5 Names somatostatin receptor type 5 somatostatin receptor subtype 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3
Summary	Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010].
Disorder MIM:	182455
Disorder Html:	Somatostatin analog, resistance to (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001172560.1	NP_001166031.1	somatostatin receptor type 5
NM_001053.4	NP_001044.1	somatostatin receptor type 5
XM_006720936.2	XP_006720999.1	somatostatin receptor type 5 isoform X1
NM_001053.3	NP_001044.1	somatostatin receptor type 5

Pathways from BioSystems

Homologies

Homo sapiens (human)	SSTR5	NP_001166031.1
Mus musculus (house mouse)	Sstr5	NP_035555.1
Danio rerio (zebrafish)	zgc:85682	NP_998462.1
Xenopus tropicalis (tropical clawed frog)	sstr5	XP_002932329.2
Canis lupus familiaris (dog)	SSTR5	XP_003434920.1
Rattus norvegicus (Norway rat)	Sstr5	NP_037014.2
Pan troglodytes (chimpanzee)	SSTR5	XP_003314946.1
Bos taurus (cattle)	SSTR5	XP_005224651.1
Gallus gallus (chicken)	SSTR5	NP_001020005.1

Gene Ontology
Bibliography

Related articles in PubMed

The oncogenic role of the spliced somatostatin receptor sst5TMD4 variant in prostate cancer.
Hormaechea-Agulla D, Jim?nez-Vacas JM, G?mez-G?mez E, L-L?pez F, Carrasco-Valiente J, Valero-Rosa J, Moreno MM, S?nchez-S?nchez R, Ortega-Salas R, Gracia-Navarro F, Culler MD, Ib??ez-Costa A, Gahete MD, Requena MJ, Casta?o JP, Luque RM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4682-4696(2017 Nov)

Clinical Importance of Somatostatin Receptor 2 (SSTR2) and Somatostatin Receptor 5 (SSTR5) Expression in Thyrotropin-Producing Pituitary Adenoma (TSHoma).
Yu B, Zhang Z, Song H, Chi Y, Shi C, Xu M
Medical science monitor : international medical journal of experimental and clinical research231947-1955(2017 Apr)

Somatostatin receptor 5 is a prominent regulator of signaling pathways in cells with coexpression of Cannabinoid receptors 1.
Zou S, Somvanshi RK, Kumar U
Neuroscience340218-231(2017 Jan)

The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients.
Gahete MD, Rinc?n-Fern?ndez D, Dur?n-Prado M, Hergueta-Redondo M, Ib??ez-Costa A, Rojo-Sebasti?n A, Gracia-Navarro F, Culler MD, Casanovas O, Moreno-Bueno G, Luque RM, Casta?o JP
Oncotarget7(37)60110-60122(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

sst5TMD4 is overexpressed in PCa, especially in those patients with a worse prognosis, and plays an important pathophysiologic role in PCa, which suggesting its potential as a biomarker and/or therapeutic target
Title: The oncogenic role of the spliced somatostatin receptor sst5TMD4 variant in prostate cancer.

In cotransfected HEK-293 cells, SSTR5 and CB1R existed in a constitutive heteromeric complex under basal condition, which was disrupted upon agonist treatments. Furthermore, concurrent receptor activation led to preferential formation of SSTR5 homodimer and dissociation of CB1R homodimer.
Title: Somatostatin receptor 5 is a prominent regulator of signaling pathways in cells with coexpression of Cannabinoid receptors 1.

Combination treatment increased both SSTR2 and SSTR5 mRNA and protein levels in DU-145 cells. The data suggest that this combination therapy may be a good candidate for patients with advanced metastatic Prostate cancer (PCa) do not respond to androgen deprivation.
Title: Octreotide in combination with AT-101 induces cytotoxicity and apoptosis through up-regulation of somatostatin receptors 2 and 5 in DU-145 prostate cancer cells.

A truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors.
Title: Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors.

Data showed that the distribution of somatostatin receptor (SSTR) subtypes among the 199 pancreatic neuroendocrine tumors (PNETs) was: SSTR2 (54.8%), SSTR1 (53.3%), SSTR4 (51.8%), SSTR5 (33.7%), and SSTR3 (28.6%).
Title: Prognostic Value of Somatostatin Receptor Subtypes in Pancreatic Neuroendocrine Tumors.

The following SSTR5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SSTR5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15729	NM_001053.4 Latest version!	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu15729	NM_001172560.1 Latest version!	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu15729	XM_006720936.2 Latest version!	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu15729	NM_001053.3	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SSTR5 ( NM_001172560.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166031.1 Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15729
Clone ID Related Accession (Same CDS sequence)	NM_001172560.1 , NM_001053.4 , XM_006720936.2 , NM_001053.3
Accession Version	NM_001172560.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	somatostatin receptor type 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009041.10. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) has an alternate 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK308381.1, DA558178.1 [ECO:0000331] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166031.1
CDS	72..1166
Translation	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL

Target ORF information:

RefSeq Version	NM_001172560.1
Organism	Homo sapiens(human)
Definition	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172560.1

ORF Insert Sequence:

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SSTR5 ( NM_001053.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001044.1 Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15729
Clone ID Related Accession (Same CDS sequence)	NM_001172560.1 , NM_001053.4 , XM_006720936.2 , NM_001053.3
Accession Version	NM_001053.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	somatostatin receptor type 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009041.10. On Jun 2, 2019 this sequence version replaced NM_001053.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AK308381.1, SRR6380202.55195.5 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001044.1
CDS	44..1138
Translation	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL

Target ORF information:

RefSeq Version	NM_001053.4
Organism	Homo sapiens(human)
Definition	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001053.4

ORF Insert Sequence:

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SSTR5 ( NM_001053.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001044.1 Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15729
Clone ID Related Accession (Same CDS sequence)	NM_001172560.1 , NM_001053.4 , XM_006720936.2 , NM_001053.3
Accession Version	NM_001053.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	somatostatin receptor type 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009041.10. On Feb 24, 2010 this sequence version replaced NM_001053.2. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001044.1
CDS	89..1183
Translation	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL

Target ORF information:

RefSeq Version	NM_001053.3
Organism	Homo sapiens(human)
Definition	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001053.3

ORF Insert Sequence:

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SSTR5 ( XM_006720936.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006720999.1 Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant X1, mRNA.

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CloneID	OHu15729
Clone ID Related Accession (Same CDS sequence)	NM_001172560.1 , NM_001053.4 , XM_006720936.2 , NM_001053.3
Accession Version	XM_006720936.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	somatostatin receptor type 5 isoform X1
Comment

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006720999.1
Translation	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL

Target ORF information:

RefSeq Version	XM_006720936.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens somatostatin receptor 5 (SSTR5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006720936.2

ORF Insert Sequence:

ATGGAGCCCC TGTTCCCAGC CTCCACGCCC AGCTGGAACG CCTCCTCCCC GGGGGCTGCC 
TCTGGAGGCG GTGACAACAG GACGCTGGTG GGGCCGGCGC CCTCGGCAGG GGCCCGGGCG 
GTGCTGGTGC CCGTGCTGTA CCTGCTGGTG TGTGCGGCCG GGCTGGGCGG GAACACGCTG 
GTCATCTACG TGGTGCTGCG CTTCGCCAAG ATGAAGACCG TCACCAACAT CTACATTCTC 
AACCTGGCAG TGGCCGACGT CCTGTACATG CTGGGGCTGC CTTTCCTGGC CACGCAGAAC 
GCCGCGTCCT TCTGGCCCTT CGGCCCCGTC CTGTGCCGCC TGGTCATGAC GCTGGACGGC 
GTCAACCAGT TCACCAGTGT CTTCTGCCTG ACAGTCATGA GCGTGGACCG CTACCTGGCA 
GTGGTGCACC CGCTGAGCTC GGCCCGCTGG CGCCGCCCGC GTGTGGCCAA GCTGGCGAGC 
GCCGCGGCCT GGGTCCTGTC TCTGTGCATG TCGCTGCCGC TCCTGGTGTT CGCGGACGTG 
CAGGAGGGCG GTACCTGCAA CGCCAGCTGG CCGGAGCCCG TGGGGCTGTG GGGCGCCGTC 
TTCATCATCT ACACGGCCGT GCTGGGCTTC TTCGCGCCGC TGCTGGTCAT CTGCCTGTGC 
TACCTGCTCA TCGTGGTGAA GGTGAGGGCG GCGGGCGTGC GCGTGGGCTG CGTGCGGCGG 
CGCTCGGAGC GGAAGGTGAC GCGCATGGTG TTGGTGGTGG TGCTGGTGTT TGCGGGATGT 
TGGCTGCCCT TCTTCACCGT CAACATCGTC AACCTGGCCG TGGCGCTGCC CCAGGAGCCC 
GCCTCCGCCG GCCTCTACTT CTTCGTGGTC ATCCTCTCCT ACGCCAACAG CTGTGCCAAC 
CCCGTCCTCT ACGGCTTCCT CTCTGACAAC TTCCGCCAGA GCTTCCAGAA GGTTCTGTGC 
CTCCGCAAGG GCTCTGGTGC CAAGGACGCT GACGCCACGG AGCCGCGTCC AGACAGGATC 
CGGCAGCAGC AGGAGGCCAC GCCACCCGCG CACCGCGCCG CAGCCAACGG GCTTATGCAG 
ACCAGCAAGC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The oncogenic role of the spliced somatostatin receptor sst5TMD4 variant in prostate cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4682-4696(2017 Nov)
Hormaechea-Agulla D,Jim?nez-Vacas JM,G?mez-G?mez E,L-L?pez F,Carrasco-Valiente J,Valero-Rosa J,Moreno MM,S?nchez-S?nchez R,Ortega-Salas R,Gracia-Navarro F,Culler MD,Ib??ez-Costa A,Gahete MD,Requena MJ,Casta?o JP,Luque RM

Clinical Importance of Somatostatin Receptor 2 (SSTR2) and Somatostatin Receptor 5 (SSTR5) Expression in Thyrotropin-Producing Pituitary Adenoma (TSHoma).
Medical science monitor : international medical journal of experimental and clinical research231947-1955(2017 Apr)
Yu B,Zhang Z,Song H,Chi Y,Shi C,Xu M

Somatostatin receptor 5 is a prominent regulator of signaling pathways in cells with coexpression of Cannabinoid receptors 1.
Neuroscience340218-231(2017 Jan)
Zou S,Somvanshi RK,Kumar U

The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients.
Oncotarget7(37)60110-60122(2016 Sep)
Gahete MD,Rinc?n-Fern?ndez D,Dur?n-Prado M,Hergueta-Redondo M,Ib??ez-Costa A,Rojo-Sebasti?n A,Gracia-Navarro F,Culler MD,Casanovas O,Moreno-Bueno G,Luque RM,Casta?o JP

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SSTR5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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