Gene Symbol | SRC |
Entrez Gene ID | 6714 |
Full Name | SRC proto-oncogene, non-receptor tyrosine kinase |
Synonyms | ASV,SRC1,THC6,c-SRC,p60-Src |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Colon cancer, advanced, somatic, 114500 (3); ?Thrombocytopenia 6, 616937 (3) |