Gene Symbol | SOS1 |
Entrez Gene ID | 6654 |
Full Name | SOS Ras/Rac guanine nucleotide exchange factor 1 |
Synonyms | GF1,GGF1,GINGF,HGF,NS4,SOS-1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | ?Fibromatosis, gingival, 1, 135300 (3); Noonan syndrome 4, 610733 (3) |