SORD cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SORD
Entrez Gene ID	6652
Full Name	sorbitol dehydrogenase
Synonyms	HEL-S-95n,SORD1
General protein information	Preferred Names sorbitol dehydrogenase Names sorbitol dehydrogenase L-iditol 2-dehydrogenase epididymis secretory sperm binding protein Li 95n
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q21.1
Summary	Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010].
Disorder MIM:	182500
Disorder Html:	?Cataract, congenital (2)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003104.6	NP_003095.2	sorbitol dehydrogenase
NM_003104.5	NP_003095.2	sorbitol dehydrogenase

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Sord	NP_058748.2
Drosophila melanogaster (fruit fly)	Sodh-1	NP_477348.1
Drosophila melanogaster (fruit fly)	Sodh-2	NP_524311.1
Saccharomyces cerevisiae (baker's yeast)	SOR2	NP_010035.1
Kluyveromyces lactis	KLLA0D05511g	XP_453306.1
Pan troglodytes (chimpanzee)	SORD	XP_003952695.1
Canis lupus familiaris (dog)	SORD	XP_544659.2
Mus musculus (house mouse)	Sord	NP_666238.1
Gallus gallus (chicken)	SORD	XP_413719.1
Schizosaccharomyces pombe (fission yeast)	tms1	NP_595120.1
Xenopus tropicalis (tropical clawed frog)	sord	NP_001011264.1
Bos taurus (cattle)	SORD	NP_001032397.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003584	XP_313338.3
Caenorhabditis elegans (roundworm)	CELE_R04B5.5	NP_505591.1
Saccharomyces cerevisiae (baker's yeast)	SOR1	NP_012693.1
Magnaporthe oryzae (rice blast fungus)	MGG_01176	XP_003714060.1
	SORD	XP_001111041.1
Eremothecium gossypii	AGOS_ABR229C	NP_983178.1
Neurospora crassa	NCU00891	XP_964807.1
Homo sapiens (human)	SORD	NP_003095.2
Danio rerio (zebrafish)	LOC570613	NP_001165890.1
Caenorhabditis elegans (roundworm)	CELE_R04B5.6	NP_505590.1
Arabidopsis thaliana (thale cress)	AT5G51970	NP_200010.1
Oryza sativa (rice)	Os08g0545200	NP_001062412.1

Gene Ontology
Bibliography

Related articles in PubMed

Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5.
Winges A, Garcia TB, Prager P, Wiedemann P, Kohen L, Bringmann A, Hollborn M
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie254(12)2387-2400(2016 Dec)

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Sorbitol dehydrogenase: structure, function and ligand design.
El-Kabbani O, Darmanin C, Chung RP
Current medicinal chemistry11(4)465-76(2004 Feb)

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.
Pauly TA, Ekstrom JL, Beebe DA, Chrunyk B, Cunningham D, Griffor M, Kamath A, Lee SE, Madura R, Mcguire D, Subashi T, Wasilko D, Watts P, Mylari BL, Oates PJ, Adams PD, Rath VL
Structure (London, England : 1993)11(9)1071-85(2003 Sep)

Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase.
Darmanin C, Iwata T, Carper DA, Sparrow LG, Chung RP, El-Kabbani O
Acta crystallographica. Section D, Biological crystallography59(Pt 3)558-60(2003 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SDH gene expression was increased by hypoxia and oxidative stress, but not extracellular hyperosmolarity. Hyperosmolarity and hypoxia did not alter the SDH protein level.
Title: Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5.

One of the most striking changes involved sorbitol dehydrogenase, a key enzyme in the polyol pathway. Validation studies revealed dramatically increased sorbitol dehydrogenase concentrations and activity in adenomas and cancer cell lines, along with important changes in the expression of other enzymes in the same (AKR1B1) and related (KHK) pathways.
Title: Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study.

Thus, our findings suggest that the -888G > C polymorphism in the SORD gene is not involved in the pathogenesis of diabtic retinopathy in type 2 diabetes.
Title: Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians.

The SDH level was significantly decreased in patients with proliferative compared with non-proliferative retinopathy in both insulin and oral diabetic groups.
Title: Aldo-keto reductase and sorbitol dehydrogenase enzymes in Egyptian diabetic patients with and without proliferative diabetic retinopathy.

Meta-analysis of gene-disease association. (HuGE Navigator)
Title: Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".

The following SORD gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SORD cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55559	NM_003104.6 Latest version!	Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu55559	NM_003104.5	Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SORD ( NM_003104.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_003095.2 Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55559
Clone ID Related Accession (Same CDS sequence)	NM_003104.6 , NM_003104.5
Accession Version	NM_003104.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	sorbitol dehydrogenase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U07361.1, BI258813.1, BC021085.2, DA530494.1 and AC091117.5. On Nov 23, 2018 this sequence version replaced NM_003104.5. Transcript Variant: This variant (1) represents the protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.10961.1, SRR1660805.25593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000267814.14/ ENSP00000267814.9 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CGGCCAAGCC CAACAACCTT TCCCTGGTGG TGCACGGACC GGGGGACTTG 
CGCCTGGAGA ACTATCCTAT CCCTGAACCA GGCCCAAATG AGGTCTTGCT GAGGATGCAT 
TCTGTTGGAA TCTGTGGCTC AGATGTCCAC TACTGGGAGT ATGGTCGAAT TGGGAATTTT 
ATTGTGAAAA AGCCCATGGT GCTGGGACAT GAAGCTTCGG GAACAGTCGA AAAAGTGGGA 
TCATCGGTAA AGCACCTAAA ACCAGGTGAT CGTGTTGCCA TCGAGCCTGG TGCTCCCCGA 
GAAAATGATG AATTCTGCAA GATGGGCCGA TACAATCTGT CACCTTCCAT CTTCTTCTGT 
GCCACGCCCC CCGATGACGG GAACCTCTGC CGGTTCTATA AGCACAATGC AGCCTTTTGT 
TACAAGCTTC CTGACAATGT CACCTTTGAG GAAGGCGCCC TGATCGAGCC ACTTTCTGTG 
GGGATCCATG CCTGCAGGAG AGGCGGAGTT ACCCTGGGAC ACAAGGTCCT TGTGTGTGGA 
GCTGGGCCAA TCGGGATGGT CACTTTGCTC GTGGCCAAAG CAATGGGAGC AGCTCAAGTA 
GTGGTGACTG ATCTGTCTGC TACCCGATTG TCCAAAGCCA AGGAGATTGG GGCTGATTTA 
GTCCTCCAGA TCTCCAAGGA GAGCCCTCAG GAAATCGCCA GGAAAGTAGA AGGTCAGCTG 
GGGTGCAAGC CGGAAGTCAC CATCGAGTGC ACGGGGGCAG AGGCCTCCAT CCAGGCGGGC 
ATCTACGCCA CTCGCTCTGG TGGGAACCTC GTGCTTGTGG GGCTGGGCTC TGAGATGACC 
ACCGTACCCC TACTGCATGC AGCCATCCGG GAGGTGGATA TCAAGGGCGT GTTTCGATAC 
TGCAACACGT GGCCAGTGGC GATTTCGATG CTTGCGTCCA AGTCTGTGAA TGTAAAACCC 
CTCGTCACCC ATAGGTTTCC TCTGGAGAAA GCTCTGGAGG CCTTTGAAAC ATTTAAAAAG 
GGATTGGGGT TGAAAATCAT GCTCAAGTGT GACCCCAGTG ACCAGAATCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003095.2
CDS	90..1163
Translation	MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP

Target ORF information:

RefSeq Version	NM_003104.6
Organism	Homo sapiens(human)
Definition	Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003104.6

ORF Insert Sequence:

ATGGCGGCGG CGGCCAAGCC CAACAACCTT TCCCTGGTGG TGCACGGACC GGGGGACTTG 
CGCCTGGAGA ACTATCCTAT CCCTGAACCA GGCCCAAATG AGGTCTTGCT GAGGATGCAT 
TCTGTTGGAA TCTGTGGCTC AGATGTCCAC TACTGGGAGT ATGGTCGAAT TGGGAATTTT 
ATTGTGAAAA AGCCCATGGT GCTGGGACAT GAAGCTTCGG GAACAGTCGA AAAAGTGGGA 
TCATCGGTAA AGCACCTAAA ACCAGGTGAT CGTGTTGCCA TCGAGCCTGG TGCTCCCCGA 
GAAAATGATG AATTCTGCAA GATGGGCCGA TACAATCTGT CACCTTCCAT CTTCTTCTGT 
GCCACGCCCC CCGATGACGG GAACCTCTGC CGGTTCTATA AGCACAATGC AGCCTTTTGT 
TACAAGCTTC CTGACAATGT CACCTTTGAG GAAGGCGCCC TGATCGAGCC ACTTTCTGTG 
GGGATCCATG CCTGCAGGAG AGGCGGAGTT ACCCTGGGAC ACAAGGTCCT TGTGTGTGGA 
GCTGGGCCAA TCGGGATGGT CACTTTGCTC GTGGCCAAAG CAATGGGAGC AGCTCAAGTA 
GTGGTGACTG ATCTGTCTGC TACCCGATTG TCCAAAGCCA AGGAGATTGG GGCTGATTTA 
GTCCTCCAGA TCTCCAAGGA GAGCCCTCAG GAAATCGCCA GGAAAGTAGA AGGTCAGCTG 
GGGTGCAAGC CGGAAGTCAC CATCGAGTGC ACGGGGGCAG AGGCCTCCAT CCAGGCGGGC 
ATCTACGCCA CTCGCTCTGG TGGGAACCTC GTGCTTGTGG GGCTGGGCTC TGAGATGACC 
ACCGTACCCC TACTGCATGC AGCCATCCGG GAGGTGGATA TCAAGGGCGT GTTTCGATAC 
TGCAACACGT GGCCAGTGGC GATTTCGATG CTTGCGTCCA AGTCTGTGAA TGTAAAACCC 
CTCGTCACCC ATAGGTTTCC TCTGGAGAAA GCTCTGGAGG CCTTTGAAAC ATTTAAAAAG 
GGATTGGGGT TGAAAATCAT GCTCAAGTGT GACCCCAGTG ACCAGAATCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SORD ( NM_003104.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003095.2 Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55559
Clone ID Related Accession (Same CDS sequence)	NM_003104.6 , NM_003104.5
Accession Version	NM_003104.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	sorbitol dehydrogenase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB031906.1, U07361.1, BI258813.1, BC021085.2 and DA530494.1. On Jul 9, 2010 this sequence version replaced NM_003104.4. Transcript Variant: This variant (1) represents the protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.47868.1, SRR1660809.11240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGG CGGCCAAGCC CAACAACCTT TCCCTGGTGG TGCACGGACC GGGGGACTTG 
CGCCTGGAGA ACTATCCTAT CCCTGAACCA GGCCCAAATG AGGTCTTGCT GAGGATGCAT 
TCTGTTGGAA TCTGTGGCTC AGATGTCCAC TACTGGGAGT ATGGTCGAAT TGGGAATTTT 
ATTGTGAAAA AGCCCATGGT GCTGGGACAT GAAGCTTCGG GAACAGTCGA AAAAGTGGGA 
TCATCGGTAA AGCACCTAAA ACCAGGTGAT CGTGTTGCCA TCGAGCCTGG TGCTCCCCGA 
GAAAATGATG AATTCTGCAA GATGGGCCGA TACAATCTGT CACCTTCCAT CTTCTTCTGT 
GCCACGCCCC CCGATGACGG GAACCTCTGC CGGTTCTATA AGCACAATGC AGCCTTTTGT 
TACAAGCTTC CTGACAATGT CACCTTTGAG GAAGGCGCCC TGATCGAGCC ACTTTCTGTG 
GGGATCCATG CCTGCAGGAG AGGCGGAGTT ACCCTGGGAC ACAAGGTCCT TGTGTGTGGA 
GCTGGGCCAA TCGGGATGGT CACTTTGCTC GTGGCCAAAG CAATGGGAGC AGCTCAAGTA 
GTGGTGACTG ATCTGTCTGC TACCCGATTG TCCAAAGCCA AGGAGATTGG GGCTGATTTA 
GTCCTCCAGA TCTCCAAGGA GAGCCCTCAG GAAATCGCCA GGAAAGTAGA AGGTCAGCTG 
GGGTGCAAGC CGGAAGTCAC CATCGAGTGC ACGGGGGCAG AGGCCTCCAT CCAGGCGGGC 
ATCTACGCCA CTCGCTCTGG TGGGAACCTC GTGCTTGTGG GGCTGGGCTC TGAGATGACC 
ACCGTACCCC TACTGCATGC AGCCATCCGG GAGGTGGATA TCAAGGGCGT GTTTCGATAC 
TGCAACACGT GGCCAGTGGC GATTTCGATG CTTGCGTCCA AGTCTGTGAA TGTAAAACCC 
CTCGTCACCC ATAGGTTTCC TCTGGAGAAA GCTCTGGAGG CCTTTGAAAC ATTTAAAAAG 
GGATTGGGGT TGAAAATCAT GCTCAAGTGT GACCCCAGTG ACCAGAATCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003095.2
CDS	181..1254
Translation	MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP

Target ORF information:

RefSeq Version	NM_003104.5
Organism	Homo sapiens(human)
Definition	Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003104.5

ORF Insert Sequence:

ATGGCGGCGG CGGCCAAGCC CAACAACCTT TCCCTGGTGG TGCACGGACC GGGGGACTTG 
CGCCTGGAGA ACTATCCTAT CCCTGAACCA GGCCCAAATG AGGTCTTGCT GAGGATGCAT 
TCTGTTGGAA TCTGTGGCTC AGATGTCCAC TACTGGGAGT ATGGTCGAAT TGGGAATTTT 
ATTGTGAAAA AGCCCATGGT GCTGGGACAT GAAGCTTCGG GAACAGTCGA AAAAGTGGGA 
TCATCGGTAA AGCACCTAAA ACCAGGTGAT CGTGTTGCCA TCGAGCCTGG TGCTCCCCGA 
GAAAATGATG AATTCTGCAA GATGGGCCGA TACAATCTGT CACCTTCCAT CTTCTTCTGT 
GCCACGCCCC CCGATGACGG GAACCTCTGC CGGTTCTATA AGCACAATGC AGCCTTTTGT 
TACAAGCTTC CTGACAATGT CACCTTTGAG GAAGGCGCCC TGATCGAGCC ACTTTCTGTG 
GGGATCCATG CCTGCAGGAG AGGCGGAGTT ACCCTGGGAC ACAAGGTCCT TGTGTGTGGA 
GCTGGGCCAA TCGGGATGGT CACTTTGCTC GTGGCCAAAG CAATGGGAGC AGCTCAAGTA 
GTGGTGACTG ATCTGTCTGC TACCCGATTG TCCAAAGCCA AGGAGATTGG GGCTGATTTA 
GTCCTCCAGA TCTCCAAGGA GAGCCCTCAG GAAATCGCCA GGAAAGTAGA AGGTCAGCTG 
GGGTGCAAGC CGGAAGTCAC CATCGAGTGC ACGGGGGCAG AGGCCTCCAT CCAGGCGGGC 
ATCTACGCCA CTCGCTCTGG TGGGAACCTC GTGCTTGTGG GGCTGGGCTC TGAGATGACC 
ACCGTACCCC TACTGCATGC AGCCATCCGG GAGGTGGATA TCAAGGGCGT GTTTCGATAC 
TGCAACACGT GGCCAGTGGC GATTTCGATG CTTGCGTCCA AGTCTGTGAA TGTAAAACCC 
CTCGTCACCC ATAGGTTTCC TCTGGAGAAA GCTCTGGAGG CCTTTGAAAC ATTTAAAAAG 
GGATTGGGGT TGAAAATCAT GCTCAAGTGT GACCCCAGTG ACCAGAATCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie254(12)2387-2400(2016 Dec)
Winges A,Garcia TB,Prager P,Wiedemann P,Kohen L,Bringmann A,Hollborn M

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Sorbitol dehydrogenase: structure, function and ligand design.
Current medicinal chemistry11(4)465-76(2004 Feb)
El-Kabbani O,Darmanin C,Chung RP

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.
Structure (London, England : 1993)11(9)1071-85(2003 Sep)
Pauly TA,Ekstrom JL,Beebe DA,Chrunyk B,Cunningham D,Griffor M,Kamath A,Lee SE,Madura R,Mcguire D,Subashi T,Wasilko D,Watts P,Mylari BL,Oates PJ,Adams PD,Rath VL

Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase.
Acta crystallographica. Section D, Biological crystallography59(Pt 3)558-60(2003 Mar)
Darmanin C,Iwata T,Carper DA,Sparrow LG,Chung RP,El-Kabbani O

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SORD cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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