SNTA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SNTA1
Entrez Gene ID	6640
Full Name	syntrophin alpha 1
Synonyms	LQT12,SNT1,TACIP1,dJ1187J4.5
General protein information	Preferred Names syntrophin alpha 1 Names alpha-1-syntrophin 59 kDa dystrophin-associated protein A1 acidic component 1 acidic alpha 1 syntrophin dystrophin-associated protein A1, 59kDa, acidic component pro-TGF-alpha cytoplasmic domain-interacting protein 1 syntrophin-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q11.21
Summary	Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].
Disorder MIM:	601017
Disorder Html:	Long QT syndrome 12, 612955 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005260517.1	XP_005260574.1	alpha-1-syntrophin isoform X1
NM_003098.2	NP_003089.1	alpha-1-syntrophin
XM_024451971.1	XP_024307739.1	alpha-1-syntrophin isoform X4
NM_003098.3	NP_003089.1	alpha-1-syntrophin
XM_011529008.1	XP_011527310.1	alpha-1-syntrophin isoform X3
XM_011529007.1	XP_011527309.1	alpha-1-syntrophin isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Snta1	NP_033254.2
Xenopus tropicalis (tropical clawed frog)	snta1	NP_001072684.1
Canis lupus familiaris (dog)	SNTA1	XP_005635403.1
Rattus norvegicus (Norway rat)	Snta1	NP_001094371.1
Pan troglodytes (chimpanzee)	SNTA1	XP_003316908.1
Homo sapiens (human)	SNTA1	NP_003089.1
	SNTA1	XP_001105682.1
Bos taurus (cattle)	SNTA1	NP_001069366.1

Gene Ontology
Bibliography

Related articles in PubMed

The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.
Rein-Fischboeck L, Pohl R, Haberl EM, Weiss TS, Buechler C
Experimental and molecular pathology103(2)204-209(2017 10)

The gene encoding the inwardly rectifying potassium channel Kir4.1 may be involved in sudden infant death syndrome.
Opdal SH, Vege ?, Stray-Pedersen A, Rognum TO
Acta paediatrica (Oslo, Norway : 1992)106(9)1474-1480(2017 Sep)

Endogenous N-terminal Domain Cleavage Modulates ?1D-Adrenergic Receptor Pharmacodynamics.
Kountz TS, Lee KS, Aggarwal-Howarth S, Curran E, Park JM, Harris DA, Stewart A, Hendrickson J, Camp ND, Wolf-Yadlin A, Wang EH, Scott JD, Hague C
The Journal of biological chemistry291(35)18210-21(2016 08)

?1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.
Choi JI, Wang C, Thomas MJ, Pitt GS
PloS one11(3)e0152355(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Low SNTA expression is associated with non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.
Title: The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.

A novel SNTA1 variant is likely causative for drug induced long-QT syndrome by augmenting the late sodium current.
Title: ?1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.

In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes.
Title: The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.

our results present a possible mechanism of Rac1 activation involving SNTA1 and emphasise its role in ROS generation, cell migration, and acquisition of malignancy.
Title: Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells.

alpha-Syntrophin, which resides in nuclei of myocytes, functions as the upstream mediator of nuclear nNOS translocation and nNOS-dependent mitochondrial biogenesis.
Title: Nuclear recruitment of neuronal nitric-oxide synthase by ?-syntrophin is crucial for the induction of mitochondrial biogenesis.

The following SNTA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNTA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19503	NM_003098.3 Latest version!	Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu105154	XM_024451971.1 Latest version!	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu53095	XM_005260517.1 Latest version!	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu60658	XM_011529007.1 Latest version!	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu60659	XM_011529008.1 Latest version!	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu19503	NM_003098.2	Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SNTA1 ( NM_003098.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003089.1 Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.

Price & Availability↑

CloneID	OHu19503
Clone ID Related Accession (Same CDS sequence)	NM_003098.2 , NM_003098.3
Accession Version	NM_003098.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U40571.1 and AU118614.1. This sequence is a reference standard in the RefSeqGene project. On Feb 19, 2002 this sequence version replaced NM_003098.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC026215.2, SRR1163657.476723.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCAGCT GGACCTGCAC 
TCGTGTCCCA AAACCATAGT CTTCATCATC CACTCCTTCC TGTCGGCCAA AGTCACCCGC 
CTCGGGCTGT TGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003089.1
CDS	273..1790
Translation	MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA

Target ORF information:

RefSeq Version	NM_003098.2
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003098.2

ORF Insert Sequence:

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCAGCT GGACCTGCAC 
TCGTGTCCCA AAACCATAGT CTTCATCATC CACTCCTTCC TGTCGGCCAA AGTCACCCGC 
CTCGGGCTGT TGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNTA1 ( NM_003098.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003089.1 Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.

Price & Availability↑

CloneID	OHu19503
Clone ID Related Accession (Same CDS sequence)	NM_003098.2 , NM_003098.3
Accession Version	NM_003098.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355392.7. On Aug 31, 2019 this sequence version replaced NM_003098.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291994.1, BC026215.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCAGCT GGACCTGCAC 
TCGTGTCCCA AAACCATAGT CTTCATCATC CACTCCTTCC TGTCGGCCAA AGTCACCCGC 
CTCGGGCTGT TGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003089.1
CDS	144..1661
Translation	MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA

Target ORF information:

RefSeq Version	NM_003098.3
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003098.3

ORF Insert Sequence:

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCAGCT GGACCTGCAC 
TCGTGTCCCA AAACCATAGT CTTCATCATC CACTCCTTCC TGTCGGCCAA AGTCACCCGC 
CTCGGGCTGT TGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNTA1 ( XM_024451971.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307739.1 Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu105154
Clone ID Related Accession (Same CDS sequence)	XM_024451971.1
Accession Version	XM_024451971.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTATTC TCATTTCCAA GATCTTCAAG GGATTGGCAG CTGACCAGAC AGAGGCCCTT 
TTTGTGGGGG ATGCCATCCT GTCTGTGAAT GGGGAAGACT TGTCCTCTGC TACCCATGAT 
GAGGCGGTGC AGGTCCTCAA GAAGACAGGC AAGGAGGTGG TGCTGGAGGT CAAGTATATG 
AAGGACGTCT CACCGTATTT CAAGAACTCT ACTGGTGGGA CCTCGGTCGG CTGGGACTCA 
CCTCCTGCCT CACCCCTTCA GCGGCAGCCT TCCTCCCCTG GCCCCACACC CCGGAACTTC 
AGCGAGGCCA AACACATGTC CTTGAAGATG GCATATGTCT CGAAGAGGTG CACCCCCAAT 
GACCCGGAGC CCAGGTATCT GGAGATCTGC TCGGCAGATG GTCAAGACAC CCTCTTCCTG 
AGGGCCAAGG ATGAGGCTAG TGCGAGGTCG TGGGCGACTG CCATCCAAGC CCAGGTCAAT 
ACTCTGACGC CGCGGGTCAA GGATGAGCTG CAGGCACTGT TGGCAGCCAC CAGCACAGCT 
GGGAGCCAGG ACATCAAGCA GATTGGCTGG CTAACTGAGC AGCTGCCCAG TGGGGGCACA 
GCCCCCACCC TGGCCCTGCT AACTGAAAAG GAACTGCTCC TCTACTTGTC TCTCCCCGAG 
ACCCGCGAGG CCCTGAGCCG GCCAGCCCGT ACTGCCCCAC TCATCGCCAC CAGACTGGTG 
CACTCAGGCC CCTCCAAGGG CTCAGTGCCC TACGATGCAG AGCTCTCTTT TGCCCTGCGC 
ACGGGCACGC GTCACGGTGT GGACACTCAC CTGTTCAGCG TGGAGTCACC GCAGGAGCTG 
GCTGCCTGGA CCCGCCAGCT TGTGGATGGC TGTCACCGGG CCGCCGAGGG TGTGCAGGAG 
GTGTCTACAG CCTGCACGTG GAATGGGCGT CCCTGCAGCC TGTCTGTGCA CATCGACAAG 
GGCTTCACAC TGTGGGCGGC TGAGCCAGGT GCAGCCCGAG CTGTGCTCCT GCGACAGCCC 
TTCGAGAAGC TGCAGATGTC TTCAGATGAC GGTGCCAGTC TCCTTTTCCT GGATTTTGGA 
GGTGCTGAAG GCGAGATCCA GCTGGACCTG CACTCGTGTC CCAAAACCAT AGTCTTCATC 
ATCCACTCCT TCCTGTCGGC CAAAGTCACC CGCCTCGGGC TGTTGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307739.1
CDS	273..1463
Translation	MPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA

Target ORF information:

RefSeq Version	XM_024451971.1
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451971.1

ORF Insert Sequence:

ATGCCTATTC TCATTTCCAA GATCTTCAAG GGATTGGCAG CTGACCAGAC AGAGGCCCTT 
TTTGTGGGGG ATGCCATCCT GTCTGTGAAT GGGGAAGACT TGTCCTCTGC TACCCATGAT 
GAGGCGGTGC AGGTCCTCAA GAAGACAGGC AAGGAGGTGG TGCTGGAGGT CAAGTATATG 
AAGGACGTCT CACCGTATTT CAAGAACTCT ACTGGTGGGA CCTCGGTCGG CTGGGACTCA 
CCTCCTGCCT CACCCCTTCA GCGGCAGCCT TCCTCCCCTG GCCCCACACC CCGGAACTTC 
AGCGAGGCCA AACACATGTC CTTGAAGATG GCATATGTCT CGAAGAGGTG CACCCCCAAT 
GACCCGGAGC CCAGGTATCT GGAGATCTGC TCGGCAGATG GTCAAGACAC CCTCTTCCTG 
AGGGCCAAGG ATGAGGCTAG TGCGAGGTCG TGGGCGACTG CCATCCAAGC CCAGGTCAAT 
ACTCTGACGC CGCGGGTCAA GGATGAGCTG CAGGCACTGT TGGCAGCCAC CAGCACAGCT 
GGGAGCCAGG ACATCAAGCA GATTGGCTGG CTAACTGAGC AGCTGCCCAG TGGGGGCACA 
GCCCCCACCC TGGCCCTGCT AACTGAAAAG GAACTGCTCC TCTACTTGTC TCTCCCCGAG 
ACCCGCGAGG CCCTGAGCCG GCCAGCCCGT ACTGCCCCAC TCATCGCCAC CAGACTGGTG 
CACTCAGGCC CCTCCAAGGG CTCAGTGCCC TACGATGCAG AGCTCTCTTT TGCCCTGCGC 
ACGGGCACGC GTCACGGTGT GGACACTCAC CTGTTCAGCG TGGAGTCACC GCAGGAGCTG 
GCTGCCTGGA CCCGCCAGCT TGTGGATGGC TGTCACCGGG CCGCCGAGGG TGTGCAGGAG 
GTGTCTACAG CCTGCACGTG GAATGGGCGT CCCTGCAGCC TGTCTGTGCA CATCGACAAG 
GGCTTCACAC TGTGGGCGGC TGAGCCAGGT GCAGCCCGAG CTGTGCTCCT GCGACAGCCC 
TTCGAGAAGC TGCAGATGTC TTCAGATGAC GGTGCCAGTC TCCTTTTCCT GGATTTTGGA 
GGTGCTGAAG GCGAGATCCA GCTGGACCTG CACTCGTGTC CCAAAACCAT AGTCTTCATC 
ATCCACTCCT TCCTGTCGGC CAAAGTCACC CGCCTCGGGC TGTTGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNTA1 ( XM_005260517.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005260574.1 Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu53095
Clone ID Related Accession (Same CDS sequence)	XM_005260517.1
Accession Version	XM_005260517.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCTGGA CCTGCACTCG 
TGTCCCAAAA CCATAGTCTT CATCATCCAC TCCTTCCTGT CGGCCAAAGT CACCCGCCTC 
GGGCTGTTGG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005260574.1
CDS	234..1748
Translation	MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEILDLHSCPKTIVFIIHSFLSAKVTRLGLLA

Target ORF information:

RefSeq Version	XM_005260517.1
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005260517.1

ORF Insert Sequence:

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGCCT GCACGTGGAA TGGGCGTCCC 
TGCAGCCTGT CTGTGCACAT CGACAAGGGC TTCACACTGT GGGCGGCTGA GCCAGGTGCA 
GCCCGAGCTG TGCTCCTGCG ACAGCCCTTC GAGAAGCTGC AGATGTCTTC AGATGACGGT 
GCCAGTCTCC TTTTCCTGGA TTTTGGAGGT GCTGAAGGCG AGATCCTGGA CCTGCACTCG 
TGTCCCAAAA CCATAGTCTT CATCATCCAC TCCTTCCTGT CGGCCAAAGT CACCCGCCTC 
GGGCTGTTGG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNTA1 ( XM_011529007.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527309.1 Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu60658
Clone ID Related Accession (Same CDS sequence)	XM_011529007.1
Accession Version	XM_011529007.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGGTG TGCTGGGAGG ATCTGGGAGT 
GTCCCTCTGC CTGCACGTGG AATGGGCGTC CCTGCAGCCT GTCTGTGCAC ATCGACAAGG 
GCTTCACACT GTGGGCGGCT GAGCCAGGTG CAGCCCGAGC TGTGCTCCTG CGACAGCCCT 
TCGAGAAGCT GCAGATGTCT TCAGATGACG GTGCCAGTCT CCTTTTCCTG GATTTTGGAG 
GTGCTGAAGG CGAGATCCAG CTGGACCTGC ACTCGTGTCC CAAAACCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527309.1
CDS	234..1724
Translation	MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTGVLGGSGSVPLPARGMGVPAACLCTSTRASHCGRLSQVQPELCSCDSPSRSCRCLQMTVPVSFSWILEVLKARSSWTCTRVPKP

Target ORF information:

RefSeq Version	XM_011529007.1
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529007.1

ORF Insert Sequence:

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGGTG TGCTGGGAGG ATCTGGGAGT 
GTCCCTCTGC CTGCACGTGG AATGGGCGTC CCTGCAGCCT GTCTGTGCAC ATCGACAAGG 
GCTTCACACT GTGGGCGGCT GAGCCAGGTG CAGCCCGAGC TGTGCTCCTG CGACAGCCCT 
TCGAGAAGCT GCAGATGTCT TCAGATGACG GTGCCAGTCT CCTTTTCCTG GATTTTGGAG 
GTGCTGAAGG CGAGATCCAG CTGGACCTGC ACTCGTGTCC CAAAACCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNTA1 ( XM_011529008.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527310.1 Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu60659
Clone ID Related Accession (Same CDS sequence)	XM_011529008.1
Accession Version	XM_011529008.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1488bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alpha-1-syntrophin isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGGTG TGCTGGGAGG ATCTGGGAGT 
GTCCCTCTGC CTGCACGTGG AATGGGCGTC CCTGCAGCCT GTCTGTGCAC ATCGACAAGG 
GCTTCACACT GTGGGCGGCT GAGCCAGGTG CAGCCCGAGC TGTGCTCCTG CGACAGCCCT 
TCGAGAAGCT GCAGATGTCT TCAGATGACG GTGCCAGTCT CCTTTTCCTG GATTTTGGAG 
GTGCTGAAGG CGAGATCCTG GACCTGCACT CGTGTCCCAA AACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527310.1
CDS	234..1721
Translation	MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTGVLGGSGSVPLPARGMGVPAACLCTSTRASHCGRLSQVQPELCSCDSPSRSCRCLQMTVPVSFSWILEVLKARSWTCTRVPKP

Target ORF information:

RefSeq Version	XM_011529008.1
Organism	Homo sapiens(human)
Definition	Homo sapiens syntrophin alpha 1 (SNTA1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529008.1

ORF Insert Sequence:

ATGGCGTCCG GCAGGCGCGC CCCGCGCACC GGGCTGCTGG AGCTGCGCGC CGGGGCGGGC 
TCGGGGGCCG GCGGCGAGCG ATGGCAGCGG GTGCTGCTGA GTCTGGCGGA GGACGTGCTG 
ACCGTGAGCC CCGCCGACGG CGACCCTGGT CCCGAGCCCG GCGCTCCGCG GGAGCAGGAG 
CCCGCGCAGC TCAACGGCGC CGCGGAGCCG GGCGCCGGGC CCCCGCAGCT GCCAGAGGCG 
CTACTGCTCC AGCGGCGCCG CGTGACGGTG CGCAAGGCCG ACGCCGGTGG GCTGGGCATC 
AGCATCAAAG GCGGCCGGGA GAACAAGATG CCTATTCTCA TTTCCAAGAT CTTCAAGGGA 
TTGGCAGCTG ACCAGACAGA GGCCCTTTTT GTGGGGGATG CCATCCTGTC TGTGAATGGG 
GAAGACTTGT CCTCTGCTAC CCATGATGAG GCGGTGCAGG TCCTCAAGAA GACAGGCAAG 
GAGGTGGTGC TGGAGGTCAA GTATATGAAG GACGTCTCAC CGTATTTCAA GAACTCTACT 
GGTGGGACCT CGGTCGGCTG GGACTCACCT CCTGCCTCAC CCCTTCAGCG GCAGCCTTCC 
TCCCCTGGCC CCACACCCCG GAACTTCAGC GAGGCCAAAC ACATGTCCTT GAAGATGGCA 
TATGTCTCGA AGAGGTGCAC CCCCAATGAC CCGGAGCCCA GGTATCTGGA GATCTGCTCG 
GCAGATGGTC AAGACACCCT CTTCCTGAGG GCCAAGGATG AGGCTAGTGC GAGGTCGTGG 
GCGACTGCCA TCCAAGCCCA GGTCAATACT CTGACGCCGC GGGTCAAGGA TGAGCTGCAG 
GCACTGTTGG CAGCCACCAG CACAGCTGGG AGCCAGGACA TCAAGCAGAT TGGCTGGCTA 
ACTGAGCAGC TGCCCAGTGG GGGCACAGCC CCCACCCTGG CCCTGCTAAC TGAAAAGGAA 
CTGCTCCTCT ACTTGTCTCT CCCCGAGACC CGCGAGGCCC TGAGCCGGCC AGCCCGTACT 
GCCCCACTCA TCGCCACCAG ACTGGTGCAC TCAGGCCCCT CCAAGGGCTC AGTGCCCTAC 
GATGCAGAGC TCTCTTTTGC CCTGCGCACG GGCACGCGTC ACGGTGTGGA CACTCACCTG 
TTCAGCGTGG AGTCACCGCA GGAGCTGGCT GCCTGGACCC GCCAGCTTGT GGATGGCTGT 
CACCGGGCCG CCGAGGGTGT GCAGGAGGTG TCTACAGGTG TGCTGGGAGG ATCTGGGAGT 
GTCCCTCTGC CTGCACGTGG AATGGGCGTC CCTGCAGCCT GTCTGTGCAC ATCGACAAGG 
GCTTCACACT GTGGGCGGCT GAGCCAGGTG CAGCCCGAGC TGTGCTCCTG CGACAGCCCT 
TCGAGAAGCT GCAGATGTCT TCAGATGACG GTGCCAGTCT CCTTTTCCTG GATTTTGGAG 
GTGCTGAAGG CGAGATCCTG GACCTGCACT CGTGTCCCAA AACCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.
Experimental and molecular pathology103(2)204-209(2017 10)
Rein-Fischboeck L,Pohl R,Haberl EM,Weiss TS,Buechler C

The gene encoding the inwardly rectifying potassium channel Kir4.1 may be involved in sudden infant death syndrome.
Acta paediatrica (Oslo, Norway : 1992)106(9)1474-1480(2017 Sep)
Opdal SH,Vege ?,Stray-Pedersen A,Rognum TO

Endogenous N-terminal Domain Cleavage Modulates ?1D-Adrenergic Receptor Pharmacodynamics.
The Journal of biological chemistry291(35)18210-21(2016 08)
Kountz TS,Lee KS,Aggarwal-Howarth S,Curran E,Park JM,Harris DA,Stewart A,Hendrickson J,Camp ND,Wolf-Yadlin A,Wang EH,Scott JD,Hague C

?1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.
PloS one11(3)e0152355(2016)
Choi JI,Wang C,Thomas MJ,Pitt GS

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SNTA1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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