SLC18A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC18A3
Entrez Gene ID	6572
Full Name	solute carrier family 18 member A3
Synonyms	CMS21,VACHT
General protein information	Preferred Names solute carrier family 18 member A3 Names vesicular acetylcholine transporter solute carrier family 18 (vesicular acetylcholine transporter), member 3 solute carrier family 18 (vesicular acetylcholine), member 3 solute carrier family 18, member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q11.23
Summary	This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	600336
Disorder Html:	Myasthenic syndrome, congenital, 21, presynaptic, 617239 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003055.2	NP_003046.2	vesicular acetylcholine transporter
NM_003055.3	NP_003046.2	vesicular acetylcholine transporter

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC18A3	XP_001138996.1
Rattus norvegicus (Norway rat)	Slc18a3	NP_113851.1
Danio rerio (zebrafish)	slc18a3b	NP_957401.1
Caenorhabditis elegans (roundworm)	unc-17	NP_001023602.1
Xenopus tropicalis (tropical clawed frog)	slc18a3	NP_001072859.1
	SLC18A3	XP_001107292.1
Bos taurus (cattle)	SLC18A3	XP_002699016.1
Gallus gallus (chicken)	SLC18A3	NP_996865.1
Danio rerio (zebrafish)	slc18a3a	NP_001071018.1
Homo sapiens (human)	SLC18A3	NP_003046.2
Canis lupus familiaris (dog)	SLC18A3	XP_543901.2
Mus musculus (house mouse)	Slc18a3	NP_068358.2
Drosophila melanogaster (fruit fly)	VAChT	NP_477138.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002369	XP_312587.5

Gene Ontology
Bibliography

Related articles in PubMed

Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome.
Aran A, Segel R, Kaneshige K, Gulsuner S, Renbaum P, Oliphant S, Meirson T, Weinberg-Shukron A, Hershkovitz Y, Zeligson S, Lee MK, Samson AO, Parsons SM, King MC, Levy-Lahad E, Walsh T
Neurology88(11)1021-1028(2017 Mar)

Gene expression profiles in peripheral blood mononuclear cells of Asian obstructive sleep apnea patients.
Lin SW, Tsai CN, Lee YS, Chu SF, Chen NH
Biomedical journal37(2)60-70(2014 Mar-Apr)

Upregulation of Lhx8 increase VAChT expression and ACh release in neuronal cell line SHSY5Y.
Li H, Jin G, Zhu P, Zou L, Shi J, Yi X, Zhang X, Tian M, Qin J
Neuroscience letters559184-8(2014 Jan)

Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma.
Lau JK, Brown KC, Thornhill BA, Crabtree CM, Dom AM, Witte TR, Hardman WE, McNees CA, Stover CA, Carpenter AB, Luo H, Chen YC, Shiflett BS, Dasgupta P
Cancer research73(4)1328-39(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of this study suggest that the Gly360Arg mutant VAChT protein undergoes posttranslational degradation.
Title: Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome.

PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations
Title: Gene expression profiles in peripheral blood mononuclear cells of Asian obstructive sleep apnea patients.

Expression of VAChT is increased in neuronal cell lines following upregulation of Lhx8.
Title: Upregulation of Lhx8 increase VAChT expression and ACh release in neuronal cell line SHSY5Y.

alpha-Synuclein expression in axons to the distal gut correlates closely with expression of the cholinergic marker, VAChT.
Title: Selective expression of ?-synuclein-immunoreactivity in vesicular acetylcholine transporter-immunoreactive axons in the guinea pig rectum and human colon.

Data indicate that siRNA-mediated attenuation of vesicular acetylcholine transporter (VAChT, SLC18A3) reversed the apoptotic activity of vesamicol.
Title: Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma.

The following SLC18A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC18A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30133	NM_003055.3 Latest version!	Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu30133	NM_003055.2	Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC18A3 ( NM_003055.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003046.2 Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.

Price & Availability↑

CloneID	OHu30133
Clone ID Related Accession (Same CDS sequence)	NM_003055.2 , NM_003055.3
Accession Version	NM_003055.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	vesicular acetylcholine transporter
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U09210.1, BC007765.2 and AC073366.4. This sequence is a reference standard in the RefSeqGene project. On Dec 1, 2006 this sequence version replaced NM_003055.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: U09210.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCCG CGGAACCTGC GGGCCAGGCC CGGGCGGCGG CCACCAAGCT GTCGGAGGCT 
GTGGGCGCGG CGCTGCAGGA GCCCCGGCGG CAGAGGCGCC TGGTGCTTGT TATCGTGTGC 
GTGGCGCTGT TACTGGACAA CATGCTGTAC ATGGTCATCG TGCCCATAGT GCCCGACTAC 
ATCGCCCACA TGCGCGGGGG CGGCGAGGGC CCCACCCGGA CTCCCGAGGT GTGGGAGCCC 
ACCCTGCCGC TGCCCACTCC GGCCAATGCC AGCGCCTACA CGGCCAACAC CTCGGCGTCC 
CCGACAGCTG CGTGGCCAGC GGGCTCAGCC CTTCGGCCCC GCTACCCTAC GGAGAGCGAA 
GACGTGAAGA TCGGGGTGCT GTTTGCTTCC AAGGCTATCC TGCAGCTGCT AGTGAACCCC 
TTGAGCGGGC CCTTCATCGA CCGCATGAGC TACGACGTGC CGCTGCTGAT CGGCCTGGGC 
GTCATGTTCG CCTCTACAGT CCTGTTCGCC TTCGCCGAGG ACTACGCCAC GCTGTTCGCG 
GCGCGCAGCC TGCAGGGCCT GGGCTCAGCC TTCGCCGACA CGTCTGGCAT AGCCATGATC 
GCCGATAAGT ACCCGGAGGA GCCGGAGCGC AGTCGTGCAC TGGGCGTGGC GCTGGCCTTC 
ATTAGCTTCG GAAGCCTAGT GGCCCCGCCC TTCGGGGGCA TCCTCTATGA GTTCGCCGGC 
AAGCGCGTGC CCTTCTTGGT GCTAGCTGCC GTGTCGCTCT TTGACGCGCT GTTGCTGCTG 
GCAGTGGCCA AACCCTTCTC GGCGGCTGCA CGGGCTCGGG CCAACCTGCC AGTGGGCACT 
CCCATCCACC GCCTCATGCT AGACCCCTAC ATTGCCGTGG TGGCCGGCGC GCTCACCACC 
TGTAACATTC CCCTCGCCTT CCTCGAACCC ACCATTGCCA CGTGGATGAA GCATACGATG 
GCGGCTTCCG AGTGGGAGAT GGGCATGGCC TGGCTGCCGG CCTTCGTGCC TCATGTGCTG 
GGCGTCTACC TCACCGTGCG CCTGGCGGCG CGCTACCCAC ACCTGCAGTG GCTGTACGGC 
GCGCTTGGGC TGGCTGTGAT CGGCGCCAGC TCGTGCATCG TGCCCGCCTG CCGCTCCTTC 
GCGCCGCTAG TGGTCTCACT ATGCGGCCTC TGTTTTGGCA TAGCCCTAGT CGACACAGCA 
CTGCTGCCCA CGCTCGCCTT CCTGGTGGAC GTGCGCCATG TCTCAGTCTA TGGCAGCGTC 
TACGCCATCG CCGACATCTC CTATTCGGTG GCCTACGCGC TCGGGCCCAT AGTGGCAGGC 
CACATTGTGC ACTCGCTGGG CTTTGAGCAG CTCAGCCTTG GCATGGGACT GGCCAACCTG 
CTCTATGCTC CCGTCTTGCT GCTGCTCCGC AACGTGGGCC TCCTGACGCG CTCCCGTTCC 
GAGCGCGATG TGCTGCTTGA TGAGCCACCG CAAGGTCTGT ACGATGCGGT GCGCCTGCGT 
GAGCGTCCTG TGTCTGGCCA GGACGGCGAG CCTCGCAGCC CGCCTGGCCC TTTTGATGCG 
TGCGAGGACG ACTACAACTA CTACTACACC CGCAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003046.2
CDS	441..2039
Translation	MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS

Target ORF information:

RefSeq Version	NM_003055.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003055.2

ORF Insert Sequence:

ATGGAATCCG CGGAACCTGC GGGCCAGGCC CGGGCGGCGG CCACCAAGCT GTCGGAGGCT 
GTGGGCGCGG CGCTGCAGGA GCCCCGGCGG CAGAGGCGCC TGGTGCTTGT TATCGTGTGC 
GTGGCGCTGT TACTGGACAA CATGCTGTAC ATGGTCATCG TGCCCATAGT GCCCGACTAC 
ATCGCCCACA TGCGCGGGGG CGGCGAGGGC CCCACCCGGA CTCCCGAGGT GTGGGAGCCC 
ACCCTGCCGC TGCCCACTCC GGCCAATGCC AGCGCCTACA CGGCCAACAC CTCGGCGTCC 
CCGACAGCTG CGTGGCCAGC GGGCTCAGCC CTTCGGCCCC GCTACCCTAC GGAGAGCGAA 
GACGTGAAGA TCGGGGTGCT GTTTGCTTCC AAGGCTATCC TGCAGCTGCT AGTGAACCCC 
TTGAGCGGGC CCTTCATCGA CCGCATGAGC TACGACGTGC CGCTGCTGAT CGGCCTGGGC 
GTCATGTTCG CCTCTACAGT CCTGTTCGCC TTCGCCGAGG ACTACGCCAC GCTGTTCGCG 
GCGCGCAGCC TGCAGGGCCT GGGCTCAGCC TTCGCCGACA CGTCTGGCAT AGCCATGATC 
GCCGATAAGT ACCCGGAGGA GCCGGAGCGC AGTCGTGCAC TGGGCGTGGC GCTGGCCTTC 
ATTAGCTTCG GAAGCCTAGT GGCCCCGCCC TTCGGGGGCA TCCTCTATGA GTTCGCCGGC 
AAGCGCGTGC CCTTCTTGGT GCTAGCTGCC GTGTCGCTCT TTGACGCGCT GTTGCTGCTG 
GCAGTGGCCA AACCCTTCTC GGCGGCTGCA CGGGCTCGGG CCAACCTGCC AGTGGGCACT 
CCCATCCACC GCCTCATGCT AGACCCCTAC ATTGCCGTGG TGGCCGGCGC GCTCACCACC 
TGTAACATTC CCCTCGCCTT CCTCGAACCC ACCATTGCCA CGTGGATGAA GCATACGATG 
GCGGCTTCCG AGTGGGAGAT GGGCATGGCC TGGCTGCCGG CCTTCGTGCC TCATGTGCTG 
GGCGTCTACC TCACCGTGCG CCTGGCGGCG CGCTACCCAC ACCTGCAGTG GCTGTACGGC 
GCGCTTGGGC TGGCTGTGAT CGGCGCCAGC TCGTGCATCG TGCCCGCCTG CCGCTCCTTC 
GCGCCGCTAG TGGTCTCACT ATGCGGCCTC TGTTTTGGCA TAGCCCTAGT CGACACAGCA 
CTGCTGCCCA CGCTCGCCTT CCTGGTGGAC GTGCGCCATG TCTCAGTCTA TGGCAGCGTC 
TACGCCATCG CCGACATCTC CTATTCGGTG GCCTACGCGC TCGGGCCCAT AGTGGCAGGC 
CACATTGTGC ACTCGCTGGG CTTTGAGCAG CTCAGCCTTG GCATGGGACT GGCCAACCTG 
CTCTATGCTC CCGTCTTGCT GCTGCTCCGC AACGTGGGCC TCCTGACGCG CTCCCGTTCC 
GAGCGCGATG TGCTGCTTGA TGAGCCACCG CAAGGTCTGT ACGATGCGGT GCGCCTGCGT 
GAGCGTCCTG TGTCTGGCCA GGACGGCGAG CCTCGCAGCC CGCCTGGCCC TTTTGATGCG 
TGCGAGGACG ACTACAACTA CTACTACACC CGCAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC18A3 ( NM_003055.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003046.2 Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.

Price & Availability↑

CloneID	OHu30133
Clone ID Related Accession (Same CDS sequence)	NM_003055.2 , NM_003055.3
Accession Version	NM_003055.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	vesicular acetylcholine transporter
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U09210.1, BC007765.2 and AC073366.4. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003055.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC007765.2, U09210.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000374115.5/ ENSP00000363229.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAATCCG CGGAACCTGC GGGCCAGGCC CGGGCGGCGG CCACCAAGCT GTCGGAGGCT 
GTGGGCGCGG CGCTGCAGGA GCCCCGGCGG CAGAGGCGCC TGGTGCTTGT TATCGTGTGC 
GTGGCGCTGT TACTGGACAA CATGCTGTAC ATGGTCATCG TGCCCATAGT GCCCGACTAC 
ATCGCCCACA TGCGCGGGGG CGGCGAGGGC CCCACCCGGA CTCCCGAGGT GTGGGAGCCC 
ACCCTGCCGC TGCCCACTCC GGCCAATGCC AGCGCCTACA CGGCCAACAC CTCGGCGTCC 
CCGACAGCTG CGTGGCCAGC GGGCTCAGCC CTTCGGCCCC GCTACCCTAC GGAGAGCGAA 
GACGTGAAGA TCGGGGTGCT GTTTGCTTCC AAGGCTATCC TGCAGCTGCT AGTGAACCCC 
TTGAGCGGGC CCTTCATCGA CCGCATGAGC TACGACGTGC CGCTGCTGAT CGGCCTGGGC 
GTCATGTTCG CCTCTACAGT CCTGTTCGCC TTCGCCGAGG ACTACGCCAC GCTGTTCGCG 
GCGCGCAGCC TGCAGGGCCT GGGCTCAGCC TTCGCCGACA CGTCTGGCAT AGCCATGATC 
GCCGATAAGT ACCCGGAGGA GCCGGAGCGC AGTCGTGCAC TGGGCGTGGC GCTGGCCTTC 
ATTAGCTTCG GAAGCCTAGT GGCCCCGCCC TTCGGGGGCA TCCTCTATGA GTTCGCCGGC 
AAGCGCGTGC CCTTCTTGGT GCTAGCTGCC GTGTCGCTCT TTGACGCGCT GTTGCTGCTG 
GCAGTGGCCA AACCCTTCTC GGCGGCTGCA CGGGCTCGGG CCAACCTGCC AGTGGGCACT 
CCCATCCACC GCCTCATGCT AGACCCCTAC ATTGCCGTGG TGGCCGGCGC GCTCACCACC 
TGTAACATTC CCCTCGCCTT CCTCGAACCC ACCATTGCCA CGTGGATGAA GCATACGATG 
GCGGCTTCCG AGTGGGAGAT GGGCATGGCC TGGCTGCCGG CCTTCGTGCC TCATGTGCTG 
GGCGTCTACC TCACCGTGCG CCTGGCGGCG CGCTACCCAC ACCTGCAGTG GCTGTACGGC 
GCGCTTGGGC TGGCTGTGAT CGGCGCCAGC TCGTGCATCG TGCCCGCCTG CCGCTCCTTC 
GCGCCGCTAG TGGTCTCACT ATGCGGCCTC TGTTTTGGCA TAGCCCTAGT CGACACAGCA 
CTGCTGCCCA CGCTCGCCTT CCTGGTGGAC GTGCGCCATG TCTCAGTCTA TGGCAGCGTC 
TACGCCATCG CCGACATCTC CTATTCGGTG GCCTACGCGC TCGGGCCCAT AGTGGCAGGC 
CACATTGTGC ACTCGCTGGG CTTTGAGCAG CTCAGCCTTG GCATGGGACT GGCCAACCTG 
CTCTATGCTC CCGTCTTGCT GCTGCTCCGC AACGTGGGCC TCCTGACGCG CTCCCGTTCC 
GAGCGCGATG TGCTGCTTGA TGAGCCACCG CAAGGTCTGT ACGATGCGGT GCGCCTGCGT 
GAGCGTCCTG TGTCTGGCCA GGACGGCGAG CCTCGCAGCC CGCCTGGCCC TTTTGATGCG 
TGCGAGGACG ACTACAACTA CTACTACACC CGCAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003046.2
CDS	432..2030
Translation	MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS

Target ORF information:

RefSeq Version	NM_003055.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 18 member A3 (SLC18A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003055.3

ORF Insert Sequence:

ATGGAATCCG CGGAACCTGC GGGCCAGGCC CGGGCGGCGG CCACCAAGCT GTCGGAGGCT 
GTGGGCGCGG CGCTGCAGGA GCCCCGGCGG CAGAGGCGCC TGGTGCTTGT TATCGTGTGC 
GTGGCGCTGT TACTGGACAA CATGCTGTAC ATGGTCATCG TGCCCATAGT GCCCGACTAC 
ATCGCCCACA TGCGCGGGGG CGGCGAGGGC CCCACCCGGA CTCCCGAGGT GTGGGAGCCC 
ACCCTGCCGC TGCCCACTCC GGCCAATGCC AGCGCCTACA CGGCCAACAC CTCGGCGTCC 
CCGACAGCTG CGTGGCCAGC GGGCTCAGCC CTTCGGCCCC GCTACCCTAC GGAGAGCGAA 
GACGTGAAGA TCGGGGTGCT GTTTGCTTCC AAGGCTATCC TGCAGCTGCT AGTGAACCCC 
TTGAGCGGGC CCTTCATCGA CCGCATGAGC TACGACGTGC CGCTGCTGAT CGGCCTGGGC 
GTCATGTTCG CCTCTACAGT CCTGTTCGCC TTCGCCGAGG ACTACGCCAC GCTGTTCGCG 
GCGCGCAGCC TGCAGGGCCT GGGCTCAGCC TTCGCCGACA CGTCTGGCAT AGCCATGATC 
GCCGATAAGT ACCCGGAGGA GCCGGAGCGC AGTCGTGCAC TGGGCGTGGC GCTGGCCTTC 
ATTAGCTTCG GAAGCCTAGT GGCCCCGCCC TTCGGGGGCA TCCTCTATGA GTTCGCCGGC 
AAGCGCGTGC CCTTCTTGGT GCTAGCTGCC GTGTCGCTCT TTGACGCGCT GTTGCTGCTG 
GCAGTGGCCA AACCCTTCTC GGCGGCTGCA CGGGCTCGGG CCAACCTGCC AGTGGGCACT 
CCCATCCACC GCCTCATGCT AGACCCCTAC ATTGCCGTGG TGGCCGGCGC GCTCACCACC 
TGTAACATTC CCCTCGCCTT CCTCGAACCC ACCATTGCCA CGTGGATGAA GCATACGATG 
GCGGCTTCCG AGTGGGAGAT GGGCATGGCC TGGCTGCCGG CCTTCGTGCC TCATGTGCTG 
GGCGTCTACC TCACCGTGCG CCTGGCGGCG CGCTACCCAC ACCTGCAGTG GCTGTACGGC 
GCGCTTGGGC TGGCTGTGAT CGGCGCCAGC TCGTGCATCG TGCCCGCCTG CCGCTCCTTC 
GCGCCGCTAG TGGTCTCACT ATGCGGCCTC TGTTTTGGCA TAGCCCTAGT CGACACAGCA 
CTGCTGCCCA CGCTCGCCTT CCTGGTGGAC GTGCGCCATG TCTCAGTCTA TGGCAGCGTC 
TACGCCATCG CCGACATCTC CTATTCGGTG GCCTACGCGC TCGGGCCCAT AGTGGCAGGC 
CACATTGTGC ACTCGCTGGG CTTTGAGCAG CTCAGCCTTG GCATGGGACT GGCCAACCTG 
CTCTATGCTC CCGTCTTGCT GCTGCTCCGC AACGTGGGCC TCCTGACGCG CTCCCGTTCC 
GAGCGCGATG TGCTGCTTGA TGAGCCACCG CAAGGTCTGT ACGATGCGGT GCGCCTGCGT 
GAGCGTCCTG TGTCTGGCCA GGACGGCGAG CCTCGCAGCC CGCCTGGCCC TTTTGATGCG 
TGCGAGGACG ACTACAACTA CTACTACACC CGCAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome.
Neurology88(11)1021-1028(2017 Mar)
Aran A,Segel R,Kaneshige K,Gulsuner S,Renbaum P,Oliphant S,Meirson T,Weinberg-Shukron A,Hershkovitz Y,Zeligson S,Lee MK,Samson AO,Parsons SM,King MC,Levy-Lahad E,Walsh T

Gene expression profiles in peripheral blood mononuclear cells of Asian obstructive sleep apnea patients.
Biomedical journal37(2)60-70(2014 Mar-Apr)
Lin SW,Tsai CN,Lee YS,Chu SF,Chen NH

Upregulation of Lhx8 increase VAChT expression and ACh release in neuronal cell line SHSY5Y.
Neuroscience letters559184-8(2014 Jan)
Li H,Jin G,Zhu P,Zou L,Shi J,Yi X,Zhang X,Tian M,Qin J

Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma.
Cancer research73(4)1328-39(2013 Feb)
Lau JK,Brown KC,Thornhill BA,Crabtree CM,Dom AM,Witte TR,Hardman WE,McNees CA,Stover CA,Carpenter AB,Luo H,Chen YC,Shiflett BS,Dasgupta P

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SLC18A3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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