GSTT2B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GSTT2B
Entrez Gene ID	653689
Full Name	glutathione S-transferase theta 2B (gene/pseudogene)
Synonyms	GSTT2P
General protein information	Preferred Names glutathione S-transferase theta 2B (gene/pseudogene) Names glutathione S-transferase theta-2B GST class-theta-2 glutathione S-transferase theta 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q11.23
Summary	The protein encoded by this gene, glutathione S-transferase (GST) theta 2B (GSTT2B), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2B gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080843.4	NP_001074312.1	glutathione S-transferase theta-2B isoform 1
NM_001080843.3	NP_001074312.1	glutathione S-transferase theta-2B isoform 1
XM_005261715.4	XP_005261772.1	glutathione S-transferase theta-2B isoform X1
NM_001363804.1	NP_001350733.1	glutathione S-transferase theta-2B isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	GSTT2	NP_000845.1
	GSTT2	XP_001088025.1
Canis lupus familiaris (dog)	LOC100686488	XP_003433484.1
Homo sapiens (human)	GSTT2B	NP_001074312.1
Pan troglodytes (chimpanzee)	GSTT2	XP_515243.2
Mus musculus (house mouse)	Gstt2	NP_034491.2
Rattus norvegicus (Norway rat)	Gstt2	NP_036928.1

Gene Ontology
Bibliography

Related articles in PubMed

Explorative genetic association study of GSTT2B copy number variant in complex disease risks.
Iorio A, Polimanti R, Calandro M, Graziano ME, Piacentini S, Bucossi S, Squitti R, Lazzarin N, Scano G, Limbruno GM, Manfellotto D, Fuciarelli M
Annals of human biology43(3)279-84(2016 May)

Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes.
Bustamante M, Danileviciute A, Espinosa A, Gonzalez JR, Subirana I, Cordier S, Chevrier C, Chatzi L, Grazuleviciene R, Sunyer J, Ibarluzea J, Ballester F, Villanueva CM, Nieuwenhuijsen M, Estivill X, Kogevinas M
BJOG : an international journal of obstetrics and gynaecology119(9)1141-6(2012 Aug)

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, K?hnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, D?ring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hypp?nen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, K?hn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, W?rtz P, Xu C, Yerges-Armstrong LM, , , , , , , , Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietil?inen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, V?lzke H, Schadt EE, Scott J, J?rvelin MR, Elliott P, Kooner JS
Nature genetics43(11)1131-8(2011 Oct)

Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.
Matejcic M, Li D, Prescott NJ, Lewis CM, Mathew CG, Parker MI
PloS one6(12)e29366(2011)

Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.
Zhao Y, Marotta M, Eichler EE, Eng C, Tanaka H
PLoS genetics5(5)e1000472(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data highlights that GSTT2B copy number variant is not associated with the investigated complex diseases in Italian patients.
Title: Explorative genetic association study of GSTT2B copy number variant in complex disease risks.

Results GSTT2B insertion allele was associated with an increased risk of being small for gestational age indicate that
Title: Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes.

results suggest that the presence of the recently described GSTT2B deletion may have a protective effect on the risk of OSCC in the Mixed Ancestry South African population
Title: Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.

study describes a previously uncharacterized 38-kilo-base (kb) long deletion polymorphism of GSTT2B located within a 61-kb DNA inverted repeat
Title: Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.

The following GSTT2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSTT2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02660	NM_001080843.4 Latest version!	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu53670	NM_001363804.1 Latest version!	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu53670	XM_005261715.4 Latest version!	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu02660	NM_001080843.3	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GSTT2B ( NM_001080843.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074312.1 Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02660
Clone ID Related Accession (Same CDS sequence)	NM_001080843.4 , NM_001080843.3
Accession Version	NM_001080843.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-02
Organism	Homo sapiens(human)
Product	glutathione S-transferase theta-2B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC253536.1. On Dec 31, 2019 this sequence version replaced NM_001080843.3. ##Evidence-Data-START## Transcript exon combination :: BC071700.1, BX376669.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 19424424 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGGTGACAC TGGCTGATCT CATGGCCCTG GAGGAGCTGA TGCAGCCGGT GGCTCTCGGC 
TATGAACTGT TTGAGGGACG GCCACGACTG GCAGCATGGC GTGGACGAGT GGAGGCTTTC 
CTGGGTGCTG AGCTATGCCA GGAGGCCCAC AGCATCATCT TGAGCATCCT GGAACAGGCG 
GCCAAGAAAA CCCTCCCAAC ACCCTCACCA GAGGCCTATC AGGCTATGCT GCTTCGAATC 
GCCAGGATCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074312.1
CDS	65..799
Translation	MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP

Target ORF information:

RefSeq Version	NM_001080843.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080843.4

ORF Insert Sequence:

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGGTGACAC TGGCTGATCT CATGGCCCTG GAGGAGCTGA TGCAGCCGGT GGCTCTCGGC 
TATGAACTGT TTGAGGGACG GCCACGACTG GCAGCATGGC GTGGACGAGT GGAGGCTTTC 
CTGGGTGCTG AGCTATGCCA GGAGGCCCAC AGCATCATCT TGAGCATCCT GGAACAGGCG 
GCCAAGAAAA CCCTCCCAAC ACCCTCACCA GAGGCCTATC AGGCTATGCT GCTTCGAATC 
GCCAGGATCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTT2B ( NM_001080843.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074312.1 Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02660
Clone ID Related Accession (Same CDS sequence)	NM_001080843.4 , NM_001080843.3
Accession Version	NM_001080843.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	glutathione S-transferase theta-2B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000350.1, BC071700.1 and AC253536.1. On Jan 17, 2014 this sequence version replaced NM_001080843.2. ##Evidence-Data-START## Transcript exon combination :: BC071700.1, BC002415.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 19424424 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGGTGACAC TGGCTGATCT CATGGCCCTG GAGGAGCTGA TGCAGCCGGT GGCTCTCGGC 
TATGAACTGT TTGAGGGACG GCCACGACTG GCAGCATGGC GTGGACGAGT GGAGGCTTTC 
CTGGGTGCTG AGCTATGCCA GGAGGCCCAC AGCATCATCT TGAGCATCCT GGAACAGGCG 
GCCAAGAAAA CCCTCCCAAC ACCCTCACCA GAGGCCTATC AGGCTATGCT GCTTCGAATC 
GCCAGGATCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074312.1
CDS	51..785
Translation	MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP

Target ORF information:

RefSeq Version	NM_001080843.3
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080843.3

ORF Insert Sequence:

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGGTGACAC TGGCTGATCT CATGGCCCTG GAGGAGCTGA TGCAGCCGGT GGCTCTCGGC 
TATGAACTGT TTGAGGGACG GCCACGACTG GCAGCATGGC GTGGACGAGT GGAGGCTTTC 
CTGGGTGCTG AGCTATGCCA GGAGGCCCAC AGCATCATCT TGAGCATCCT GGAACAGGCG 
GCCAAGAAAA CCCTCCCAAC ACCCTCACCA GAGGCCTATC AGGCTATGCT GCTTCGAATC 
GCCAGGATCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTT2B ( NM_001363804.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350733.1 Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu53670
Clone ID Related Accession (Same CDS sequence)	XM_005261715.4 , NM_001363804.1
Accession Version	NM_001363804.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-02
Organism	Homo sapiens(human)
Product	glutathione S-transferase theta-2B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC253536.1. On Jun 3, 2018 this sequence version replaced XM_005261715.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.39395.1, SRR5189655.42506.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 19424424 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGCCGGTGG CTCTCGGCTA TGAACTGTTT GAGGGACGGC CACGACTGGC AGCATGGCGT 
GGACGAGTGG AGGCTTTCCT GGGTGCTGAG CTATGCCAGG AGGCCCACAG CATCATCTTG 
AGCATCCTGG AACAGGCGGC CAAGAAAACC CTCCCAACAC CCTCACCAGA GGCCTATCAG 
GCTATGCTGC TTCGAATCGC CAGGATCCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350733.1
CDS	76..768
Translation	MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP

Target ORF information:

RefSeq Version	NM_001363804.1
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363804.1

ORF Insert Sequence:

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGCCGGTGG CTCTCGGCTA TGAACTGTTT GAGGGACGGC CACGACTGGC AGCATGGCGT 
GGACGAGTGG AGGCTTTCCT GGGTGCTGAG CTATGCCAGG AGGCCCACAG CATCATCTTG 
AGCATCCTGG AACAGGCGGC CAAGAAAACC CTCCCAACAC CCTCACCAGA GGCCTATCAG 
GCTATGCTGC TTCGAATCGC CAGGATCCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSTT2B ( XM_005261715.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005261772.1 Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu53670
Clone ID Related Accession (Same CDS sequence)	XM_005261715.4 , NM_001363804.1
Accession Version	XM_005261715.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	glutathione S-transferase theta-2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005261715.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGCCGGTGG CTCTCGGCTA TGAACTGTTT GAGGGACGGC CACGACTGGC AGCATGGCGT 
GGACGAGTGG AGGCTTTCCT GGGTGCTGAG CTATGCCAGG AGGCCCACAG CATCATCTTG 
AGCATCCTGG AACAGGCGGC CAAGAAAACC CTCCCAACAC CCTCACCAGA GGCCTATCAG 
GCTATGCTGC TTCGAATCGC CAGGATCCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005261772.1
CDS	71..763
Translation	MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP

Target ORF information:

RefSeq Version	XM_005261715.4
Organism	Homo sapiens(human)
Definition	Homo sapiens glutathione S-transferase theta 2B (gene/pseudogene) (GSTT2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005261715.4

ORF Insert Sequence:

ATGGGCCTAG AGCTGTTTCT TGACCTGGTG TCCCAGCCCA GCCGCGCCGT CTACATCTTC 
GCCAAGAAGA ATGGCATCCC CTTAGAGCTG CGCACCGTGG ATTTGGTCAA AGGGCAGCAC 
AAGAGCAAGG AGTTCTTGCA GATCAACAGC CTGGGGAAAC TGCCGACGCT CAAGGATGGT 
GATTTCATCT TGACCGAAAG CTCGGCCATC CTGATTTACC TGAGCTGTAA GTACCAGACG 
CCGGACCACT GGTATCCATC TGACCTGCAG GCTCGTGCCC GTGTTCATGA GTACCTGGGC 
TGGCATGCCG ACTGCATCCG TGGCACCTTT GGTATACCCC TGTGGGTCCA GGTGTTGGGG 
CCACTCATTG GGGTCCAGGT GCCCGAGGAG AAGGTGGAAC GCAACAGGAC TGCCATGGAC 
CAGGCCCTGC AATGGCTGGA GGACAAGTTC CTGGGGGACA GGCCCTTCCT CGCTGGCCAG 
CAGCCGGTGG CTCTCGGCTA TGAACTGTTT GAGGGACGGC CACGACTGGC AGCATGGCGT 
GGACGAGTGG AGGCTTTCCT GGGTGCTGAG CTATGCCAGG AGGCCCACAG CATCATCTTG 
AGCATCCTGG AACAGGCGGC CAAGAAAACC CTCCCAACAC CCTCACCAGA GGCCTATCAG 
GCTATGCTGC TTCGAATCGC CAGGATCCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Explorative genetic association study of GSTT2B copy number variant in complex disease risks.
Annals of human biology43(3)279-84(2016 May)
Iorio A,Polimanti R,Calandro M,Graziano ME,Piacentini S,Bucossi S,Squitti R,Lazzarin N,Scano G,Limbruno GM,Manfellotto D,Fuciarelli M

Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes.
BJOG : an international journal of obstetrics and gynaecology119(9)1141-6(2012 Aug)
Bustamante M,Danileviciute A,Espinosa A,Gonzalez JR,Subirana I,Cordier S,Chevrier C,Chatzi L,Grazuleviciene R,Sunyer J,Ibarluzea J,Ballester F,Villanueva CM,Nieuwenhuijsen M,Estivill X,Kogevinas M

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nature genetics43(11)1131-8(2011 Oct)
Chambers JC,Zhang W,Sehmi J,Li X,Wass MN,Van der Harst P,Holm H,Sanna S,Kavousi M,Baumeister SE,Coin LJ,Deng G,Gieger C,Heard-Costa NL,Hottenga JJ,K?hnel B,Kumar V,Lagou V,Liang L,Luan J,Vidal PM,Mateo Leach I,O'Reilly PF,Peden JF,Rahmioglu N,Soininen P,Speliotes EK,Yuan X,Thorleifsson G,Alizadeh BZ,Atwood LD,Borecki IB,Brown MJ,Charoen P,Cucca F,Das D,de Geus EJ,Dixon AL,D?ring A,Ehret G,Eyjolfsson GI,Farrall M,Forouhi NG,Friedrich N,Goessling W,Gudbjartsson DF,Harris TB,Hartikainen AL,Heath S,Hirschfield GM,Hofman A,Homuth G,Hypp?nen E,Janssen HL,Johnson T,Kangas AJ,Kema IP,K?hn JP,Lai S,Lathrop M,Lerch MM,Li Y,Liang TJ,Lin JP,Loos RJ,Martin NG,Moffatt MF,Montgomery GW,Munroe PB,Musunuru K,Nakamura Y,O'Donnell CJ,Olafsson I,Penninx BW,Pouta A,Prins BP,Prokopenko I,Puls R,Ruokonen A,Savolainen MJ,Schlessinger D,Schouten JN,Seedorf U,Sen-Chowdhry S,Siminovitch KA,Smit JH,Spector TD,Tan W,Teslovich TM,Tukiainen T,Uitterlinden AG,Van der Klauw MM,Vasan RS,Wallace C,Wallaschofski H,Wichmann HE,Willemsen G,W?rtz P,Xu C,Yerges-Armstrong LM,,,,,,,,Abecasis GR,Ahmadi KR,Boomsma DI,Caulfield M,Cookson WO,van Duijn CM,Froguel P,Matsuda K,McCarthy MI,Meisinger C,Mooser V,Pietil?inen KH,Schumann G,Snieder H,Sternberg MJ,Stolk RP,Thomas HC,Thorsteinsdottir U,Uda M,Waeber G,Wareham NJ,Waterworth DM,Watkins H,Whitfield JB,Witteman JC,Wolffenbuttel BH,Fox CS,Ala-Korpela M,Stefansson K,Vollenweider P,V?lzke H,Schadt EE,Scott J,J?rvelin MR,Elliott P,Kooner JS

Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.
PloS one6(12)e29366(2011)
Matejcic M,Li D,Prescott NJ,Lewis CM,Mathew CG,Parker MI

Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.
PLoS genetics5(5)e1000472(2009 May)
Zhao Y,Marotta M,Eichler EE,Eng C,Tanaka H

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GSTT2B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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