SLC5A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC5A1
Entrez Gene ID	6523
Full Name	solute carrier family 5 member 1
Synonyms	D22S675,NAGT,SGLT1
General protein information	Preferred Names solute carrier family 5 member 1 Names sodium/glucose cotransporter 1 Na+/glucose cotransporter 1 high affinity sodium-glucose cotransporter solute carrier family 5 (sodium/glucose cotransporter), member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q12.3
Summary	This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
Disorder MIM:	182380
Disorder Html:	Glucose/galactose malabsorption, 606824 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001256314.1	NP_001243243.1	sodium/glucose cotransporter 1 isoform 2
XM_011530331.1	XP_011528633.1	sodium/glucose cotransporter 1 isoform X1
NM_000343.3	NP_000334.1	sodium/glucose cotransporter 1 isoform 1
NM_000343.4	NP_000334.1	sodium/glucose cotransporter 1 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC5A1	NP_001007142.1
Xenopus tropicalis (tropical clawed frog)	LOC100498135	XP_002931963.2
Pan troglodytes (chimpanzee)	SLC5A1	XP_515093.3
Mus musculus (house mouse)	Slc5a1	NP_062784.3
Danio rerio (zebrafish)	slc5a1	NP_956975.1
	SLC5A1	XP_001112212.1
Rattus norvegicus (Norway rat)	Slc5a1	NP_037165.1
Xenopus tropicalis (tropical clawed frog)	LOC100493915	XP_004910646.1
Homo sapiens (human)	SLC5A1	NP_000334.1
Bos taurus (cattle)	SLC5A1	NP_777031.1
Gallus gallus (chicken)	SLC5A1	XP_415247.3

Gene Ontology
Bibliography

Related articles in PubMed

Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia.
Fiorentino TV, Suraci E, Arcidiacono GP, Cimellaro A, Mignogna C, Presta I, Andreozzi F, Hribal ML, Perticone F, Donato G, Luzza F, Sesti G
The Journal of clinical endocrinology and metabolism102(11)3979-3989(2017 Nov)

Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy.
Salker MS, Singh Y, Zeng N, Chen H, Zhang S, Umbach AT, Fakhri H, Kohlhofer U, Quintanilla-Martinez L, Durairaj RRP, Barros FSV, Vrljicak P, Ott S, Brucker SY, Wallwiener D, Vrhovac Maduni? I, Breljak D, Saboli? I, Koepsell H, Brosens JJ, Lang F
Scientific reports7(1)12612(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Duodenal SGLT-1 expression is increased in individuals with 1-hour postload hyperglycemia or impaired glucose tolerance, as well as in subjects with T2 Diabetes mellitus, and it positively correlates with early postload glucose excursion.
Title: Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia.

Homoeriodictyol affects both the glucose metabolism and the serotonin system in Caco-2 cells via a sodium glucose cotransporter 1 protein (SGLT-1)-meditated pathway.
Title: The flavanone homoeriodictyol increases SGLT-1-mediated glucose uptake but decreases serotonin release in differentiated Caco-2 cells.

Binding of RS1-Reg to ODC1 inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.
Title: Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase.

intracellular Na+ and sugar release occurs in a random, independent manner
Title: Stochastic steps in secondary active sugar transport.

JAK3 up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.
Title: Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes.

The following SLC5A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC5A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20381	NM_001256314.1 Latest version!	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu22190	NM_000343.4 Latest version!	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu60551	XM_011530331.1 Latest version!	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu22190	NM_000343.3	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC5A1 ( NM_001256314.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243243.1 Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20381
Clone ID Related Accession (Same CDS sequence)	NM_001256314.1
Accession Version	NM_001256314.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	sodium/glucose cotransporter 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z74021.1, AK297665.1, M24847.1 and Z83839.1. On Jan 19, 2012 this sequence version replaced NR_033411.1. Transcript Variant: This variant (2) lacks several 5' exons compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a weak Kozak sequence and a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316184.1, AK297665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142363, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END##

ATGCCAGAGT ACCTGAGGAA GCGGTTTGGA GGCCAGCGGA TCCAGGTCTA CCTTTCCCTT 
CTGTCCCTGC TGCTCTACAT TTTCACCAAG ATCTCGGCAG ACATCTTCTC GGGGGCCATA 
TTCATCAATC TGGCCTTAGG CCTGAATCTG TATTTAGCCA TCTTTCTCTT ATTGGCAATC 
ACTGCCCTTT ACACAATTAC AGGGGGCCTG GCGGCGGTGA TTTACACGGA CACCTTGCAG 
ACGGTGATCA TGCTGGTGGG GTCTTTAATC CTGACTGGGT TTGCTTTTCA CGAAGTGGGA 
GGCTATGACG CCTTCATGGA AAAGTACATG AAAGCCATTC CAACCATAGT GTCTGATGGC 
AACACCACCT TTCAGGAAAA ATGCTACACT CCAAGGGCCG ACTCCTTCCA CATCTTCCGA 
GATCCCCTCA CGGGAGACCT CCCATGGCCT GGGTTCATCT TTGGGATGTC CATCCTTACC 
TTGTGGTACT GGTGCACAGA TCAGGTCATT GTGCAGCGCT GCCTCTCAGC CAAGAATATG 
TCTCACGTGA AGGGTGGCTG CATCCTGTGT GGGTATCTAA AGCTGATGCC CATGTTCATC 
ATGGTGATGC CAGGAATGAT CAGCCGCATT CTGTACACAG AAAAAATTGC CTGTGTCGTC 
CCTTCAGAAT GTGAGAAATA TTGCGGTACC AAGGTTGGCT GTACCAACAT CGCCTATCCA 
ACCTTAGTGG TGGAGCTCAT GCCCAATGGA CTGCGAGGCC TGATGCTATC AGTCATGCTG 
GCCTCCCTCA TGAGCTCCCT GACCTCCATC TTCAACAGCG CCAGCACCCT CTTCACCATG 
GACATCTACG CCAAGGTCCG CAAGAGAGCA TCTGAGAAAG AGCTCATGAT TGCCGGAAGG 
TTGTTTATCC TGGTGCTGAT TGGCATCAGC ATCGCCTGGG TGCCCATTGT GCAGTCAGCA 
CAAAGTGGGC AACTCTTCGA TTACATCCAG TCCATCACCA GTTACTTGGG ACCACCCATT 
GCGGCTGTCT TCCTGCTTGC TATTTTCTGG AAGAGAGTCA ATGAGCCAGG AGCCTTTTGG 
GGACTGATCC TAGGACTTCT GATTGGGATT TCACGTATGA TTACTGAGTT TGCTTATGGA 
ACCGGGAGCT GCATGGAGCC CAGCAACTGT CCCACGATTA TCTGTGGGGT GCACTACTTG 
TACTTTGCCA TTATCCTCTT CGCCATTTCT TTCATCACCA TCGTGGTCAT CTCCCTCCTC 
ACCAAACCCA TTCCGGATGT GCATCTCTAC CGTCTGTGTT GGAGCCTGCG CAACAGCAAA 
GAGGAGCGTA TTGACCTGGA TGCGGAAGAG GAGAACATCC AAGAAGGCCC TAAGGAGACC 
ATTGAAATAG AAACACAAGT TCCTGAGAAG AAAAAAGGAA TCTTCAGGAG AGCCTATGAC 
CTATTTTGTG GGCTAGAGCA GCACGGTGCA CCCAAGATGA CTGAGGAAGA GGAGAAAGCC 
ATGAAGATGA AGATGACGGA CACCTCTGAG AAGCCTTTGT GGAGGACAGT GTTGAACGTC 
AATGGCATCA TCCTGGTGAC CGTGGCTGTC TTTTGCCATG CATATTTTGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243243.1
CDS	350..1963
Translation	MPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKGIFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHAYFA

Target ORF information:

RefSeq Version	NM_001256314.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256314.1

ORF Insert Sequence:

ATGCCAGAGT ACCTGAGGAA GCGGTTTGGA GGCCAGCGGA TCCAGGTCTA CCTTTCCCTT 
CTGTCCCTGC TGCTCTACAT TTTCACCAAG ATCTCGGCAG ACATCTTCTC GGGGGCCATA 
TTCATCAATC TGGCCTTAGG CCTGAATCTG TATTTAGCCA TCTTTCTCTT ATTGGCAATC 
ACTGCCCTTT ACACAATTAC AGGGGGCCTG GCGGCGGTGA TTTACACGGA CACCTTGCAG 
ACGGTGATCA TGCTGGTGGG GTCTTTAATC CTGACTGGGT TTGCTTTTCA CGAAGTGGGA 
GGCTATGACG CCTTCATGGA AAAGTACATG AAAGCCATTC CAACCATAGT GTCTGATGGC 
AACACCACCT TTCAGGAAAA ATGCTACACT CCAAGGGCCG ACTCCTTCCA CATCTTCCGA 
GATCCCCTCA CGGGAGACCT CCCATGGCCT GGGTTCATCT TTGGGATGTC CATCCTTACC 
TTGTGGTACT GGTGCACAGA TCAGGTCATT GTGCAGCGCT GCCTCTCAGC CAAGAATATG 
TCTCACGTGA AGGGTGGCTG CATCCTGTGT GGGTATCTAA AGCTGATGCC CATGTTCATC 
ATGGTGATGC CAGGAATGAT CAGCCGCATT CTGTACACAG AAAAAATTGC CTGTGTCGTC 
CCTTCAGAAT GTGAGAAATA TTGCGGTACC AAGGTTGGCT GTACCAACAT CGCCTATCCA 
ACCTTAGTGG TGGAGCTCAT GCCCAATGGA CTGCGAGGCC TGATGCTATC AGTCATGCTG 
GCCTCCCTCA TGAGCTCCCT GACCTCCATC TTCAACAGCG CCAGCACCCT CTTCACCATG 
GACATCTACG CCAAGGTCCG CAAGAGAGCA TCTGAGAAAG AGCTCATGAT TGCCGGAAGG 
TTGTTTATCC TGGTGCTGAT TGGCATCAGC ATCGCCTGGG TGCCCATTGT GCAGTCAGCA 
CAAAGTGGGC AACTCTTCGA TTACATCCAG TCCATCACCA GTTACTTGGG ACCACCCATT 
GCGGCTGTCT TCCTGCTTGC TATTTTCTGG AAGAGAGTCA ATGAGCCAGG AGCCTTTTGG 
GGACTGATCC TAGGACTTCT GATTGGGATT TCACGTATGA TTACTGAGTT TGCTTATGGA 
ACCGGGAGCT GCATGGAGCC CAGCAACTGT CCCACGATTA TCTGTGGGGT GCACTACTTG 
TACTTTGCCA TTATCCTCTT CGCCATTTCT TTCATCACCA TCGTGGTCAT CTCCCTCCTC 
ACCAAACCCA TTCCGGATGT GCATCTCTAC CGTCTGTGTT GGAGCCTGCG CAACAGCAAA 
GAGGAGCGTA TTGACCTGGA TGCGGAAGAG GAGAACATCC AAGAAGGCCC TAAGGAGACC 
ATTGAAATAG AAACACAAGT TCCTGAGAAG AAAAAAGGAA TCTTCAGGAG AGCCTATGAC 
CTATTTTGTG GGCTAGAGCA GCACGGTGCA CCCAAGATGA CTGAGGAAGA GGAGAAAGCC 
ATGAAGATGA AGATGACGGA CACCTCTGAG AAGCCTTTGT GGAGGACAGT GTTGAACGTC 
AATGGCATCA TCCTGGTGAC CGTGGCTGTC TTTTGCCATG CATATTTTGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC5A1 ( NM_000343.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000334.1 Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22190
Clone ID Related Accession (Same CDS sequence)	NM_000343.3 , NM_000343.4
Accession Version	NM_000343.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	sodium/glucose cotransporter 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ656053.2, AK312948.1 and Z83839.1. This sequence is a reference standard in the RefSeqGene project. On Mar 26, 2010 this sequence version replaced NM_000343.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M24847.1, AK312948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GTTGTTTATC CTGGTGCTGA TTGGCATCAG CATCGCCTGG 
GTGCCCATTG TGCAGTCAGC ACAAAGTGGG CAACTCTTCG ATTACATCCA GTCCATCACC 
AGTTACTTGG GACCACCCAT TGCGGCTGTC TTCCTGCTTG CTATTTTCTG GAAGAGAGTC 
AATGAGCCAG GAGCCTTTTG GGGACTGATC CTAGGACTTC TGATTGGGAT TTCACGTATG 
ATTACTGAGT TTGCTTATGG AACCGGGAGC TGCATGGAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGGG TGCACTACTT GTACTTTGCC ATTATCCTCT TCGCCATTTC TTTCATCACC 
ATCGTGGTCA TCTCCCTCCT CACCAAACCC ATTCCGGATG TGCATCTCTA CCGTCTGTGT 
TGGAGCCTGC GCAACAGCAA AGAGGAGCGT ATTGACCTGG ATGCGGAAGA GGAGAACATC 
CAAGAAGGCC CTAAGGAGAC CATTGAAATA GAAACACAAG TTCCTGAGAA GAAAAAAGGA 
ATCTTCAGGA GAGCCTATGA CCTATTTTGT GGGCTAGAGC AGCACGGTGC ACCCAAGATG 
ACTGAGGAAG AGGAGAAAGC CATGAAGATG AAGATGACGG ACACCTCTGA GAAGCCTTTG 
TGGAGGACAG TGTTGAACGT CAATGGCATC ATCCTGGTGA CCGTGGCTGT CTTTTGCCAT 
GCATATTTTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000334.1
CDS	251..2245
Translation	MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKGIFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHAYFA

Target ORF information:

RefSeq Version	NM_000343.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000343.3

ORF Insert Sequence:

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GTTGTTTATC CTGGTGCTGA TTGGCATCAG CATCGCCTGG 
GTGCCCATTG TGCAGTCAGC ACAAAGTGGG CAACTCTTCG ATTACATCCA GTCCATCACC 
AGTTACTTGG GACCACCCAT TGCGGCTGTC TTCCTGCTTG CTATTTTCTG GAAGAGAGTC 
AATGAGCCAG GAGCCTTTTG GGGACTGATC CTAGGACTTC TGATTGGGAT TTCACGTATG 
ATTACTGAGT TTGCTTATGG AACCGGGAGC TGCATGGAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGGG TGCACTACTT GTACTTTGCC ATTATCCTCT TCGCCATTTC TTTCATCACC 
ATCGTGGTCA TCTCCCTCCT CACCAAACCC ATTCCGGATG TGCATCTCTA CCGTCTGTGT 
TGGAGCCTGC GCAACAGCAA AGAGGAGCGT ATTGACCTGG ATGCGGAAGA GGAGAACATC 
CAAGAAGGCC CTAAGGAGAC CATTGAAATA GAAACACAAG TTCCTGAGAA GAAAAAAGGA 
ATCTTCAGGA GAGCCTATGA CCTATTTTGT GGGCTAGAGC AGCACGGTGC ACCCAAGATG 
ACTGAGGAAG AGGAGAAAGC CATGAAGATG AAGATGACGG ACACCTCTGA GAAGCCTTTG 
TGGAGGACAG TGTTGAACGT CAATGGCATC ATCCTGGTGA CCGTGGCTGT CTTTTGCCAT 
GCATATTTTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC5A1 ( NM_000343.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000334.1 Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22190
Clone ID Related Accession (Same CDS sequence)	NM_000343.3 , NM_000343.4
Accession Version	NM_000343.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	sodium/glucose cotransporter 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ656053.2, AK312948.1 and Z83839.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_000343.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M24847.1, CR456579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000266088.9/ ENSP00000266088.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GTTGTTTATC CTGGTGCTGA TTGGCATCAG CATCGCCTGG 
GTGCCCATTG TGCAGTCAGC ACAAAGTGGG CAACTCTTCG ATTACATCCA GTCCATCACC 
AGTTACTTGG GACCACCCAT TGCGGCTGTC TTCCTGCTTG CTATTTTCTG GAAGAGAGTC 
AATGAGCCAG GAGCCTTTTG GGGACTGATC CTAGGACTTC TGATTGGGAT TTCACGTATG 
ATTACTGAGT TTGCTTATGG AACCGGGAGC TGCATGGAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGGG TGCACTACTT GTACTTTGCC ATTATCCTCT TCGCCATTTC TTTCATCACC 
ATCGTGGTCA TCTCCCTCCT CACCAAACCC ATTCCGGATG TGCATCTCTA CCGTCTGTGT 
TGGAGCCTGC GCAACAGCAA AGAGGAGCGT ATTGACCTGG ATGCGGAAGA GGAGAACATC 
CAAGAAGGCC CTAAGGAGAC CATTGAAATA GAAACACAAG TTCCTGAGAA GAAAAAAGGA 
ATCTTCAGGA GAGCCTATGA CCTATTTTGT GGGCTAGAGC AGCACGGTGC ACCCAAGATG 
ACTGAGGAAG AGGAGAAAGC CATGAAGATG AAGATGACGG ACACCTCTGA GAAGCCTTTG 
TGGAGGACAG TGTTGAACGT CAATGGCATC ATCCTGGTGA CCGTGGCTGT CTTTTGCCAT 
GCATATTTTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000334.1
CDS	22..2016
Translation	MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKGIFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHAYFA

Target ORF information:

RefSeq Version	NM_000343.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000343.4

ORF Insert Sequence:

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GTTGTTTATC CTGGTGCTGA TTGGCATCAG CATCGCCTGG 
GTGCCCATTG TGCAGTCAGC ACAAAGTGGG CAACTCTTCG ATTACATCCA GTCCATCACC 
AGTTACTTGG GACCACCCAT TGCGGCTGTC TTCCTGCTTG CTATTTTCTG GAAGAGAGTC 
AATGAGCCAG GAGCCTTTTG GGGACTGATC CTAGGACTTC TGATTGGGAT TTCACGTATG 
ATTACTGAGT TTGCTTATGG AACCGGGAGC TGCATGGAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGGG TGCACTACTT GTACTTTGCC ATTATCCTCT TCGCCATTTC TTTCATCACC 
ATCGTGGTCA TCTCCCTCCT CACCAAACCC ATTCCGGATG TGCATCTCTA CCGTCTGTGT 
TGGAGCCTGC GCAACAGCAA AGAGGAGCGT ATTGACCTGG ATGCGGAAGA GGAGAACATC 
CAAGAAGGCC CTAAGGAGAC CATTGAAATA GAAACACAAG TTCCTGAGAA GAAAAAAGGA 
ATCTTCAGGA GAGCCTATGA CCTATTTTGT GGGCTAGAGC AGCACGGTGC ACCCAAGATG 
ACTGAGGAAG AGGAGAAAGC CATGAAGATG AAGATGACGG ACACCTCTGA GAAGCCTTTG 
TGGAGGACAG TGTTGAACGT CAATGGCATC ATCCTGGTGA CCGTGGCTGT CTTTTGCCAT 
GCATATTTTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC5A1 ( XM_011530331.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528633.1 Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant X1, mRNA.

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CloneID	OHu60551
Clone ID Related Accession (Same CDS sequence)	XM_011530331.1
Accession Version	XM_011530331.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sodium/glucose cotransporter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GGAGCCTTTT GGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528633.1
CDS	233..1531
Translation	MDSSTWSPKTTAVTRPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGREPFGD

Target ORF information:

RefSeq Version	XM_011530331.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 5 member 1 (SLC5A1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530331.1

ORF Insert Sequence:

ATGGACAGTA GCACCTGGAG CCCCAAGACC ACCGCGGTCA CCCGGCCTGT TGAGACCCAC 
GAGCTCATTC GCAATGCAGC CGATATCTCC ATCATCGTTA TCTACTTCGT GGTAGTGATG 
GCCGTCGGAC TGTGGGCTAT GTTTTCCACC AATCGTGGGA CTGTTGGAGG CTTCTTCCTG 
GCAGGCCGAA GTATGGTGTG GTGGCCGATT GGAGCCTCCC TCTTTGCTAG TAACATTGGA 
AGTGGCCACT TTGTGGGGCT GGCCGGGACT GGGGCAGCTT CAGGCATCGC CATTGGAGGC 
TTTGAATGGA ATGCCCTGGT TTTGGTGGTT GTGCTGGGCT GGCTGTTTGT CCCCATCTAT 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGGTTTGG AGGCCAGCGG 
ATCCAGGTCT ACCTTTCCCT TCTGTCCCTG CTGCTCTACA TTTTCACCAA GATCTCGGCA 
GACATCTTCT CGGGGGCCAT ATTCATCAAT CTGGCCTTAG GCCTGAATCT GTATTTAGCC 
ATCTTTCTCT TATTGGCAAT CACTGCCCTT TACACAATTA CAGGGGGCCT GGCGGCGGTG 
ATTTACACGG ACACCTTGCA GACGGTGATC ATGCTGGTGG GGTCTTTAAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGCTATGAC GCCTTCATGG AAAAGTACAT GAAAGCCATT 
CCAACCATAG TGTCTGATGG CAACACCACC TTTCAGGAAA AATGCTACAC TCCAAGGGCC 
GACTCCTTCC ACATCTTCCG AGATCCCCTC ACGGGAGACC TCCCATGGCC TGGGTTCATC 
TTTGGGATGT CCATCCTTAC CTTGTGGTAC TGGTGCACAG ATCAGGTCAT TGTGCAGCGC 
TGCCTCTCAG CCAAGAATAT GTCTCACGTG AAGGGTGGCT GCATCCTGTG TGGGTATCTA 
AAGCTGATGC CCATGTTCAT CATGGTGATG CCAGGAATGA TCAGCCGCAT TCTGTACACA 
GAAAAAATTG CCTGTGTCGT CCCTTCAGAA TGTGAGAAAT ATTGCGGTAC CAAGGTTGGC 
TGTACCAACA TCGCCTATCC AACCTTAGTG GTGGAGCTCA TGCCCAATGG ACTGCGAGGC 
CTGATGCTAT CAGTCATGCT GGCCTCCCTC ATGAGCTCCC TGACCTCCAT CTTCAACAGC 
GCCAGCACCC TCTTCACCAT GGACATCTAC GCCAAGGTCC GCAAGAGAGC ATCTGAGAAA 
GAGCTCATGA TTGCCGGAAG GGAGCCTTTT GGGGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia.
The Journal of clinical endocrinology and metabolism102(11)3979-3989(2017 Nov)
Fiorentino TV,Suraci E,Arcidiacono GP,Cimellaro A,Mignogna C,Presta I,Andreozzi F,Hribal ML,Perticone F,Donato G,Luzza F,Sesti G

Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy.
Scientific reports7(1)12612(2017 Oct)
Salker MS,Singh Y,Zeng N,Chen H,Zhang S,Umbach AT,Fakhri H,Kohlhofer U,Quintanilla-Martinez L,Durairaj RRP,Barros FSV,Vrljicak P,Ott S,Brucker SY,Wallwiener D,Vrhovac Maduni? I,Breljak D,Saboli? I,Koepsell H,Brosens JJ,Lang F

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SLC5A1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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