MRPS24 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MRPS24
Entrez Gene ID	64951
Full Name	mitochondrial ribosomal protein S24
Synonyms	HSPC335,MRP-S24,S24mt,bMRP-47,bMRP47
General protein information	Preferred Names mitochondrial ribosomal protein S24 Names 28S ribosomal protein S24, mitochondrial mitochondrial 28S ribosomal protein S24 mitochondrial small ribosomal subunit protein uS3m
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p13
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene. [provided by RefSeq, Mar 2011].
Disorder MIM:	611986

mRNA and Protein(s)

mRNA	Protein	Name
NM_032014.2	NP_114403.1	28S ribosomal protein S24, mitochondrial precursor
NM_032014.3	NP_114403.1	28S ribosomal protein S24, mitochondrial precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	MRPS24	NP_114403.1
Bos taurus (cattle)	MRPS24	NP_001040066.1
Rattus norvegicus (Norway rat)	Mrps24	NP_001071127.1
Xenopus tropicalis (tropical clawed frog)	mrps24	NP_001016526.1
Mus musculus (house mouse)	Mrps24	NP_080356.1
Caenorhabditis elegans (roundworm)	mrps-24	NP_001023176.1
Pan troglodytes (chimpanzee)	MRPS24	XP_001135905.1
	MRPS24	XP_001095116.1
Danio rerio (zebrafish)	mrps24	NP_001018518.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004404	XP_003436804.1
Drosophila melanogaster (fruit fly)	mRpS24	NP_524476.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012833	XP_306739.3

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.
Zhang Z, Gerstein M
Genomics81(5)468-80(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following MRPS24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRPS24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17262	NM_032014.3 Latest version!	Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu17262	NM_032014.2	Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MRPS24 ( NM_032014.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114403.1 Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.

Price & Availability↑

CloneID	OHu17262
Clone ID Related Accession (Same CDS sequence)	NM_032014.2 , NM_032014.3
Accession Version	NM_032014.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	28S ribosomal protein S24, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA413186.1 and BC012167.1. On Nov 14, 2006 this sequence version replaced NM_032014.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA413186.1, SRR1163657.147287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCT CCGTGTGCAG CGGGTTGCTG GGGCCACGGG TGCTGTCCTG GAGCCGAGAG 
CTGCCTTGCG CTTGGCGCGC CCTGCACACC TCCCCGGTCT GCGCCAAGAA CCGGGCGGCC 
CGAGTACGCG TAAGCAAGGG GGACAAGCCG GTGACCTACG AGGAGGCACA CGCGCCGCAC 
TACATCGCCC ACCGTAAAGG CTGGCTGTCG CTGCACACAG GTAACCTGGA TGGAGAGGAC 
CATGCCGCAG AGCGAACGGT GGAGGATGTT TTCCTTCGCA AGTTCATGTG GGGTACCTTC 
CCAGGCTGCC TGGCTGACCA GCTGGTTTTA AAGCGCCGGG GTAACCAGTT GGAGATCTGT 
GCCGTGGTCC TGAGGCAGTT GTCTCCACAC AAGTACTACT TCCTCGTGGG CTACAGTGAA 
ACTTTGCTGT CCTACTTTTA CAAATGTCCT GTGCGACTCC ACCTCCAAAC TGTGCCCTCA 
AAGGTTGTGT ATAAGTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114403.1
CDS	52..555
Translation	MAASVCSGLLGPRVLSWSRELPCAWRALHTSPVCAKNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEICAVVLRQLSPHKYYFLVGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL

Target ORF information:

RefSeq Version	NM_032014.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032014.2

ORF Insert Sequence:

ATGGCGGCCT CCGTGTGCAG CGGGTTGCTG GGGCCACGGG TGCTGTCCTG GAGCCGAGAG 
CTGCCTTGCG CTTGGCGCGC CCTGCACACC TCCCCGGTCT GCGCCAAGAA CCGGGCGGCC 
CGAGTACGCG TAAGCAAGGG GGACAAGCCG GTGACCTACG AGGAGGCACA CGCGCCGCAC 
TACATCGCCC ACCGTAAAGG CTGGCTGTCG CTGCACACAG GTAACCTGGA TGGAGAGGAC 
CATGCCGCAG AGCGAACGGT GGAGGATGTT TTCCTTCGCA AGTTCATGTG GGGTACCTTC 
CCAGGCTGCC TGGCTGACCA GCTGGTTTTA AAGCGCCGGG GTAACCAGTT GGAGATCTGT 
GCCGTGGTCC TGAGGCAGTT GTCTCCACAC AAGTACTACT TCCTCGTGGG CTACAGTGAA 
ACTTTGCTGT CCTACTTTTA CAAATGTCCT GTGCGACTCC ACCTCCAAAC TGTGCCCTCA 
AAGGTTGTGT ATAAGTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPS24 ( NM_032014.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114403.1 Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.

Price & Availability↑

CloneID	OHu17262
Clone ID Related Accession (Same CDS sequence)	NM_032014.2 , NM_032014.3
Accession Version	NM_032014.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	28S ribosomal protein S24, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA413186.1 and BC012167.1. On Nov 23, 2018 this sequence version replaced NM_032014.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.140263.1, SRR1163657.40186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000317534.6/ ENSP00000318158.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCT CCGTGTGCAG CGGGTTGCTG GGGCCACGGG TGCTGTCCTG GAGCCGAGAG 
CTGCCTTGCG CTTGGCGCGC CCTGCACACC TCCCCGGTCT GCGCCAAGAA CCGGGCGGCC 
CGAGTACGCG TAAGCAAGGG GGACAAGCCG GTGACCTACG AGGAGGCACA CGCGCCGCAC 
TACATCGCCC ACCGTAAAGG CTGGCTGTCG CTGCACACAG GTAACCTGGA TGGAGAGGAC 
CATGCCGCAG AGCGAACGGT GGAGGATGTT TTCCTTCGCA AGTTCATGTG GGGTACCTTC 
CCAGGCTGCC TGGCTGACCA GCTGGTTTTA AAGCGCCGGG GTAACCAGTT GGAGATCTGT 
GCCGTGGTCC TGAGGCAGTT GTCTCCACAC AAGTACTACT TCCTCGTGGG CTACAGTGAA 
ACTTTGCTGT CCTACTTTTA CAAATGTCCT GTGCGACTCC ACCTCCAAAC TGTGCCCTCA 
AAGGTTGTGT ATAAGTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114403.1
CDS	23..526
Translation	MAASVCSGLLGPRVLSWSRELPCAWRALHTSPVCAKNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEICAVVLRQLSPHKYYFLVGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL

Target ORF information:

RefSeq Version	NM_032014.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein S24 (MRPS24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032014.3

ORF Insert Sequence:

ATGGCGGCCT CCGTGTGCAG CGGGTTGCTG GGGCCACGGG TGCTGTCCTG GAGCCGAGAG 
CTGCCTTGCG CTTGGCGCGC CCTGCACACC TCCCCGGTCT GCGCCAAGAA CCGGGCGGCC 
CGAGTACGCG TAAGCAAGGG GGACAAGCCG GTGACCTACG AGGAGGCACA CGCGCCGCAC 
TACATCGCCC ACCGTAAAGG CTGGCTGTCG CTGCACACAG GTAACCTGGA TGGAGAGGAC 
CATGCCGCAG AGCGAACGGT GGAGGATGTT TTCCTTCGCA AGTTCATGTG GGGTACCTTC 
CCAGGCTGCC TGGCTGACCA GCTGGTTTTA AAGCGCCGGG GTAACCAGTT GGAGATCTGT 
GCCGTGGTCC TGAGGCAGTT GTCTCCACAC AAGTACTACT TCCTCGTGGG CTACAGTGAA 
ACTTTGCTGT CCTACTTTTA CAAATGTCCT GTGCGACTCC ACCTCCAAAC TGTGCCCTCA 
AAGGTTGTGT ATAAGTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.
Genomics81(5)468-80(2003 May)
Zhang Z,Gerstein M

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MRPS24 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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